Page last updated: 2024-10-22

acetazolamide and Uveitis

acetazolamide has been researched along with Uveitis in 32 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Uveitis: Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To study the effect of acetazolamide on cystoid macular edema in patients with uveitis."9.08A randomized, masked, cross-over trial of acetazolamide for cystoid macular edema in patients with uveitis. ( Chew, EY; Csaky, KG; Nussenblatt, RB; Perry, CH; Podgor, MJ; Whitcup, SM, 1996)
"We report a case of pustular psoriasis precipitated by acetazolamide, a carbonic anhydrase inhibitor."7.69Pustular psoriasis precipitated by acetazolamide. ( Fujita, M; Kojima, T; Kuroda, K; Shinkai, H; Tanabe, E, 1995)
" (1988), who first used acetazolamide (Diamox) for treatment of macular edema of various origin in a higher number of patients, let assume a positive effect of this therapy on fluid accumulation specifically inside the inner retinal layers."7.68[Therapy of cystoid diffuse macular edema after uveitis and cataract surgery with the carbonic anhydrase inhibitor acetazolamide (Diamox)]. ( Pauleikhoff, D; Schilling, H; Schrenk, M; Wessing, A, 1993)
"To study the effect of acetazolamide on cystoid macular edema in patients with uveitis."5.08A randomized, masked, cross-over trial of acetazolamide for cystoid macular edema in patients with uveitis. ( Chew, EY; Csaky, KG; Nussenblatt, RB; Perry, CH; Podgor, MJ; Whitcup, SM, 1996)
" A majority of eyes also required systemic acetazolamide (UG: 79% OFG: 87%) and had undergone at least one glaucoma-related operation prior to the Baerveldt 250 implant ((UG: 1."4.12A comparison of long-term results after Baerveldt 250 implantation in advanced uveitic vs. other forms of glaucoma. ( Anton, A; Böhringer, D; Cazana, IM; Lübke, J; Ness, T; Reinhard, T, 2022)
"We report a case of pustular psoriasis precipitated by acetazolamide, a carbonic anhydrase inhibitor."3.69Pustular psoriasis precipitated by acetazolamide. ( Fujita, M; Kojima, T; Kuroda, K; Shinkai, H; Tanabe, E, 1995)
" (1988), who first used acetazolamide (Diamox) for treatment of macular edema of various origin in a higher number of patients, let assume a positive effect of this therapy on fluid accumulation specifically inside the inner retinal layers."3.68[Therapy of cystoid diffuse macular edema after uveitis and cataract surgery with the carbonic anhydrase inhibitor acetazolamide (Diamox)]. ( Pauleikhoff, D; Schilling, H; Schrenk, M; Wessing, A, 1993)
"Initial angiographic cystoid macular edema was comparable and significantly improved after therapy in the two treatment groups."2.67[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema]. ( Guex-Crosier, Y; Herbort, CP; Othenin-Girard, P, 1992)
"Oral acetazolamide was required for IOP control in 64."1.72High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis. ( Bennett, S; Chew, S; Ma, T; Niederer, RL; Sims, JL, 2022)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199017 (53.13)18.7374
1990's8 (25.00)18.2507
2000's2 (6.25)29.6817
2010's3 (9.38)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Cazana, IM1
Böhringer, D1
Reinhard, T1
Anton, A1
Ness, T1
Lübke, J1
Ma, T1
Sims, JL1
Bennett, S1
Chew, S1
Niederer, RL1
Liu, X1
Zhang, M1
Ossewaarde-van Norel, A1
Rothova, A2
Ossewaarde-van Norel, J1
Berg, EM1
Sijssens, KM1
WARREN, CM1
GHOSH, M1
LEVY, PM1
LEOPOLD, IH1
Thurau, SR1
Sivaprasad, S1
Ikeji, F1
Xing, W1
Lightman, S1
Arrell, RW1
Molteno, AC1
Ancker, E1
Van Biljon, G1
Herschler, J1
Davis, EB1
Schilling, H1
Pauleikhoff, D1
Schrenk, M1
Wessing, A1
Kuroda, K1
Kojima, T1
Tanabe, E1
Fujita, M1
Shinkai, H1
Whitcup, SM1
Csaky, KG1
Podgor, MJ1
Chew, EY1
Perry, CH1
Nussenblatt, RB1
Flach, A1
Rho, D1
Zierhut, M1
Thiel, HJ1
Schlote, T1
Roth, M1
Simmons, RJ1
Guex-Crosier, Y1
Othenin-Girard, P1
Herbort, CP1
Sawa, M1
Brockhurst, RJ1
Schepens, CL1
Okamura, ID1
Regan, CD1
McMeel, JW1
Nissen, OI1
Hoppe, RF1
Merté, HJ1
Johnston, SS1
Ware, CF1
Brown, RM1
Mendis, U1
O'Rourke, J1
Macri, FJ1
Hale, LM1
Hopkins, DJ1
Horan, EC1
Williamson, J1
Russell, F1
Doig, WM1
Paterson, RW1
Martin, B1
Pohjola, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000115]Phase 20 participants Interventional1990-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetazolamide and Uveitis

ArticleYear
Clinical review: Update on treatment of inflammatory macular edema.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:1

    Topics: Acetazolamide; Adrenal Cortex Hormones; Algorithms; Anti-Inflammatory Agents; Drug Implants; Humans;

2011

Trials

3 trials available for acetazolamide and Uveitis

ArticleYear
Subfoveal serous retinal detachment in patients with uveitic macular edema.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2011, Volume: 129, Issue:2

    Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Female; Foll

2011
A randomized, masked, cross-over trial of acetazolamide for cystoid macular edema in patients with uveitis.
    Ophthalmology, 1996, Volume: 103, Issue:7

    Topics: Acetazolamide; Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Chronic Disease; Cross-Over S

1996
[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema].
    Klinische Monatsblatter fur Augenheilkunde, 1992, Volume: 200, Issue:5

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Diclofenac; Female; Humans; Injections; Lenses, Intra

1992

Other Studies

28 other studies available for acetazolamide and Uveitis

ArticleYear
A comparison of long-term results after Baerveldt 250 implantation in advanced uveitic vs. other forms of glaucoma.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2022, Volume: 260, Issue:9

    Topics: Acetazolamide; Follow-Up Studies; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure

2022
High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis.
    The British journal of ophthalmology, 2022, Volume: 106, Issue:11

    Topics: Acetazolamide; Female; Glaucoma; HLA-B27 Antigen; Humans; Male; Middle Aged; Ocular Hypertension; Uv

2022
[Uveitic macular edema and the pharmacotherapy].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2015, Volume: 51, Issue:2

    Topics: Acetazolamide; Adrenal Cortex Hormones; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized;

2015
DANGERS OF STEROIDS IN OPHTHALMOLOGY WITH REPORT OF A CASE OF MYCOTIC PERFORATING CORNEAL ULCER.
    Journal of the Medical Association of the State of Alabama, 1964, Volume: 33

    Topics: Acetazolamide; Bendroflumethiazide; Betamethasone; Cornea; Corneal Ulcer; Dexamethasone; Eye Injurie

1964
THERAPY OF TOXOPLASMOSIS UVEITIS.
    American journal of ophthalmology, 1965, Volume: 59

    Topics: Acetazolamide; Administration, Topical; Ascorbic Acid; Chorioretinitis; Drug Therapy; Eye; Humans; M

1965
[Cystoid macular edema in uveitis].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2005, Volume: 102, Issue:5

    Topics: Acetazolamide; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Blood-Retinal Barri

2005
Tomographic assessment of therapeutic response to uveitic macular oedema.
    Clinical & experimental ophthalmology, 2007, Volume: 35, Issue:8

    Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal;

2007
Acute tuberculous panophthalmitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1967, Volume: 78, Issue:1

    Topics: Acetazolamide; Aged; Aminosalicylic Acids; Atropine; Choroid Neoplasms; Exophthalmos; Female; Glauco

1967
Surgical technique for advanced juvenile glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:1

    Topics: Acetazolamide; Adolescent; Adult; Carbachol; Child; Child, Preschool; Colchicine; Drainage; Follow-U

1984
Modified goniotomy for inflammatory glaucoma. Histologic evidence for the mechanism of pressure reduction.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1980, Volume: 98, Issue:4

    Topics: Acetazolamide; Adult; Cataract Extraction; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressu

1980
[Therapy of cystoid diffuse macular edema after uveitis and cataract surgery with the carbonic anhydrase inhibitor acetazolamide (Diamox)].
    Klinische Monatsblatter fur Augenheilkunde, 1993, Volume: 202, Issue:3

    Topics: Acetazolamide; Adult; Aged; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Admi

1993
Pustular psoriasis precipitated by acetazolamide.
    The Journal of dermatology, 1995, Volume: 22, Issue:10

    Topics: Acetazolamide; Adult; Arthritis, Psoriatic; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Male; P

1995
Acetazolamide treatment of CME in patients with uveitis.
    Ophthalmology, 1996, Volume: 103, Issue:11

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chronic Disease; Humans; Macular Edema; Randomized Con

1996
Acetazolamide treatment of CME in patients with uveitis.
    Ophthalmology, 1996, Volume: 103, Issue:11

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chronic Disease; Humans; Macular Edema; Randomized Con

1996
Treatment of uveitic macular edema with acetazolamide.
    Documenta ophthalmologica. Advances in ophthalmology, 1999, Volume: 97, Issue:3-4

    Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Child; Drug Therapy, Combination; F

1999
Glaucoma associated with precipitates on the trabecular meshwork.
    Ophthalmology, 1979, Volume: 86, Issue:9

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Dexamethasone

1979
Clinical application of laser flare-cell meter.
    Japanese journal of ophthalmology, 1990, Volume: 34, Issue:3

    Topics: Acetazolamide; Adult; Age Factors; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous H

1990
Scleral buckling procedures. 8. Preoperative complications.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 74, Issue:6

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Anesthetics, Local; Choroid; Conjunctivitis; Dacryocysti

1965
The facility of aqueous outflow calculated from the rate of fall in applanation pressure after intravenous acetazolamide in man.
    Acta ophthalmologica, 1974, Volume: 52, Issue:3

    Topics: Acetazolamide; Adolescent; Adult; Aged; Aqueous Humor; Cataract; Diabetes Mellitus; Epinephrine; Eye

1974
[Secondary glaucoma, pathogenesis and clinic (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1974, Volume: 165, Issue:3

    Topics: Acetazolamide; Anti-Inflammatory Agents; Aqueous Humor; Eye; Eye Diseases; Eye Injuries; Glaucoma; G

1974
Iris involvement in leukaemia.
    The British journal of ophthalmology, 1973, Volume: 57, Issue:5

    Topics: Acetazolamide; Atropine; Cerebrospinal Fluid; Child, Preschool; Eye Diseases; Female; Humans; Intrao

1973
Retinal arteritis complicating herpes zoster ophthalmicus.
    The British journal of ophthalmology, 1973, Volume: 57, Issue:5

    Topics: Acetazolamide; Arteritis; Atropine; Female; Fluorescein Angiography; Fundus Oculi; Herpes Zoster Oph

1973
Studies in uveal physiology. II. Clinical studies of the anterior chamber clearance of isotopic tracers.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1970, Volume: 84, Issue:4

    Topics: Acetazolamide; Adult; Aged; Anterior Chamber; Antipyrine; Aqueous Humor; Biological Transport; Capil

1970
Emergency eye care.
    American family physician, 1972, Volume: 6, Issue:3

    Topics: Acetazolamide; Acids; Alkalies; Conjunctiva; Conjunctivitis; Corneal Injuries; Eye Burns; Eye Diseas

1972
Glaucoma in the Hallermann-Streiff syndrome.
    The British journal of ophthalmology, 1970, Volume: 54, Issue:6

    Topics: Acetazolamide; Adult; Cataract; Child, Preschool; Epinephrine; Female; Glaucoma; Hallermann's Syndro

1970
Estimation of sodium fusidate levels in human serum, aqueous humour, and vitreous body.
    The British journal of ophthalmology, 1970, Volume: 54, Issue:2

    Topics: Acetazolamide; Aged; Aqueous Humor; Cataract; Cataract Extraction; Female; Fusidic Acid; Humans; Mal

1970
Infiltration of the iris in chronic lymphatic leukaemia.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:10

    Topics: Acetazolamide; Chlorambucil; Chronic Disease; Glaucoma; Humans; Intraocular Pressure; Iris; Leukemia

1968
The glucose content of the aqueous humour in man.
    Acta ophthalmologica, 1966

    Topics: Acetazolamide; Adolescent; Adult; Aged; Animals; Aqueous Humor; Cataract; Diabetes Mellitus; Female;

1966