acetazolamide has been researched along with Tuberculosis, Meningeal in 6 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Tuberculosis, Meningeal: A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS. The organism seeds the meninges and forms microtuberculomas which subsequently rupture. The clinical course tends to be subacute, with progressions occurring over a period of several days or longer. Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA. The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes. (From Adams et al., Principles of Neurology, 6th ed, pp717-9)
Excerpt | Relevance | Reference |
---|---|---|
"There has been reports on pediatric TB meningitis manifesting with fever and seizures, altered sensorium or focal deficits." | 1.56 | Tuberculous meningitis manifesting with neuroregression in a eleven month child. ( Kasinathan, A; Palanisamy, S; Serane, VK, 2020) |
"Patients with non-communicating hydrocephalus received ventriculo-peritoneal shunts shortly after admission while communicating hydrocephalus was treated with oral acetazolamide (100 mg/kg/day) and furosemide (1 mg/kg/day) in 3-4 divided doses." | 1.31 | Long-term follow up of childhood tuberculous meningitis. ( Burger, M; Donald, P; Fertig, G; Schoeman, J; Springer, P; van Rensburg, AJ; van Zyl, F; Wait, J, 2002) |
"Noncommunicating hydrocephalus (37 children), as determined by air encephalography, was treated by ventriculoperitoneal (VP) shunting and communicating hydrocephalus (181 children), by means of daily acetazolamide and frusemide." | 1.31 | Serial lumbar CSF presure measurements and cranial computed tomographic findings in childhood tuberculous meningitits. ( Donald, PR; Laubscher, JA; Schoeman, JF, 2000) |
"Eight patients with obstructive hydrocephalus were treated surgically." | 1.26 | Hydrocephalus in tuberculous meningitis in children: treatment with acetazolamide and repeated lumbar puncture. ( Chiemchanya, S; Visudhiphan, P, 1979) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (33.33) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Authors | Studies |
---|---|
Kasinathan, A | 1 |
Serane, VK | 1 |
Palanisamy, S | 1 |
Schoeman, J | 2 |
Wait, J | 2 |
Burger, M | 1 |
van Zyl, F | 1 |
Fertig, G | 1 |
van Rensburg, AJ | 1 |
Springer, P | 1 |
Donald, P | 2 |
RICCI, G | 1 |
COPAITICH, T | 1 |
Schoeman, JF | 1 |
Laubscher, JA | 1 |
Donald, PR | 1 |
Visudhiphan, P | 1 |
Chiemchanya, S | 1 |
van Zyl, L | 1 |
Keet, M | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Randomized Double Blind Placebo Controlled Trial of Adjunctive Dexamethasone for the Treatment of HIV-infected Adults With Tuberculous Meningitis[NCT03092817] | Phase 3 | 520 participants (Actual) | Interventional | 2017-05-25 | Active, not recruiting | ||
A Randomized Double Blind Placebo Controlled Non-inferiority Trial of Adjunctive Dexamethasone for the Treatment of HIV-uninfected Adults With Tuberculous Meningitis Stratified by Leukotriene A4 Hydrolase Genotype[NCT03100786] | Phase 3 | 640 participants (Anticipated) | Interventional | 2018-02-08 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 trial available for acetazolamide and Tuberculosis, Meningeal
Article | Year |
---|---|
Tuberculous hydrocephalus: comparison of different treatments with regard to ICP, ventricular size and clinical outcome.
Topics: Acetazolamide; Antitubercular Agents; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Child; Child, | 1991 |
Tuberculous hydrocephalus: comparison of different treatments with regard to ICP, ventricular size and clinical outcome.
Topics: Acetazolamide; Antitubercular Agents; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Child; Child, | 1991 |
Tuberculous hydrocephalus: comparison of different treatments with regard to ICP, ventricular size and clinical outcome.
Topics: Acetazolamide; Antitubercular Agents; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Child; Child, | 1991 |
Tuberculous hydrocephalus: comparison of different treatments with regard to ICP, ventricular size and clinical outcome.
Topics: Acetazolamide; Antitubercular Agents; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Child; Child, | 1991 |
5 other studies available for acetazolamide and Tuberculosis, Meningeal
Article | Year |
---|---|
Tuberculous meningitis manifesting with neuroregression in a eleven month child.
Topics: Acetazolamide; Antitubercular Agents; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid; Early Medi | 2020 |
Long-term follow up of childhood tuberculous meningitis.
Topics: Acetazolamide; Anti-Inflammatory Agents; Antitubercular Agents; Brain; Child; Cognition Disorders; D | 2002 |
[Trial acetazolamide therapy of hydrocephalus in tuberculous meningitis].
Topics: Acetazolamide; Humans; Hydrocephalus; Tuberculosis, Meningeal | 1959 |
Serial lumbar CSF presure measurements and cranial computed tomographic findings in childhood tuberculous meningitits.
Topics: Acetazolamide; Antitubercular Agents; Cerebrospinal Fluid Pressure; Child; Combined Modality Therapy | 2000 |
Hydrocephalus in tuberculous meningitis in children: treatment with acetazolamide and repeated lumbar puncture.
Topics: Acetazolamide; Adolescent; Brain Edema; Child; Child, Preschool; Humans; Hydrocephalus; Infant; Spin | 1979 |