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acetazolamide and Retinal Pigment Epithelial Detachment

acetazolamide has been researched along with Retinal Pigment Epithelial Detachment in 39 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"The intraocular pressure response to a standardized dose of intravenous acetazolamide (5mg/kg) was evaluated in a "case" group of 15 patients undergoing retinal detachment (RD) surgery and in a control group of 15 patients undergoing epiretinal membrane peeling."9.19[Tonometric response to acetazolamide in patients with retinal detachment]. ( Arndt, C; Barbe, C; Ducasse, A; Zambrowski, O, 2014)
"A 36 year-old woman with idiopathic intracranial hypertension was treated with topiramate and acetazolamide."7.91Macular neurosensory retinal detachment associated with topiramate use. ( de Las Morenas Iglesias, J; Espiñeira Periñán, MÁ; Franco Ruedas, C; López-Herrero, F; Muñoz Morales, A; Sánchez-Vicente, JL, 2019)
"Treatment with acetazolamide, at a dosage of 0."5.28[Serous retinal detachment. Value of acetazolamide]. ( Gonzalez, C, 1992)
"Retinal detachments were created in one eye of each of eight cynomolgus monkeys."5.27Experimental retinal detachment. X. Effect of acetazolamide on vitreous fluorescein disappearance. ( Pederson, JE; Tsuboi, S, 1985)
"The intraocular pressure response to a standardized dose of intravenous acetazolamide (5mg/kg) was evaluated in a "case" group of 15 patients undergoing retinal detachment (RD) surgery and in a control group of 15 patients undergoing epiretinal membrane peeling."5.19[Tonometric response to acetazolamide in patients with retinal detachment]. ( Arndt, C; Barbe, C; Ducasse, A; Zambrowski, O, 2014)
"A 36 year-old woman with idiopathic intracranial hypertension was treated with topiramate and acetazolamide."3.91Macular neurosensory retinal detachment associated with topiramate use. ( de Las Morenas Iglesias, J; Espiñeira Periñán, MÁ; Franco Ruedas, C; López-Herrero, F; Muñoz Morales, A; Sánchez-Vicente, JL, 2019)
"005% and acetazolamide 250 mg were administered in order to reduce intraocular pressure, improve uveoscleral outflow, and facilitate resolution of uveal effusion."3.80Medical therapy for uveal effusion syndrome. ( Andrijević Derk, B; Benčić, G; Corluka, V; Vatavuk, Z; Zorić Geber, M, 2014)
"We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS)."3.74High altitude and retinal detachment. ( Cottrell, DG; Morris, DS; Severn, PS; Smith, J; Somner, JE; Stannard, KP, 2007)
" Detachment height was measured using a dual He-Ne beam YAG laser focusing system, and the fluid absorption rate was calculated before and after intravenous injections of saline, acetazolamide or benzolamide."1.31Inhibition of membrane-bound carbonic anhydrase enhances subretinal fluid absorption and retinal adhesiveness. ( Chiang, RK; Marmor, MF; Takeuchi, A; Wolfensberger, TJ, 2000)
"An 84-year-old woman with unstable angina pectoris was treated with subcutaneous enoxaparine (Clexane) for several days before presenting with severe pain and decreased vision in her left eye."1.31Massive choroidal hemorrhage associated with low molecular weight heparin therapy. ( Goldstein, M; Leibovitch, I; Loewenstein, A; Neudorfer, M, 2002)
"Treatment with acetazolamide, at a dosage of 0."1.28[Serous retinal detachment. Value of acetazolamide]. ( Gonzalez, C, 1992)
"Treatment with Acetazolamide provided quick recovery in the bilateral case, whereas the unilateral exudative detachment recovered without treatment after delivery."1.28Exudative retinal detachment in familial pulmonary hypertension. ( Gíslason, I; Jónasson, F; Stefánsson, E, 1991)
"Retinal detachments were created in one eye of each of eight cynomolgus monkeys."1.27Experimental retinal detachment. X. Effect of acetazolamide on vitreous fluorescein disappearance. ( Pederson, JE; Tsuboi, S, 1985)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199010 (25.64)18.7374
1990's12 (30.77)18.2507
2000's5 (12.82)29.6817
2010's12 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Muñoz Morales, A1
Sánchez-Vicente, JL1
Franco Ruedas, C1
de Las Morenas Iglesias, J1
Espiñeira Periñán, MÁ1
López-Herrero, F1
Park, JH1
Lee, EK1
Jovanović, S1
Oros, A1
Lješević, L1
Peković, S1
Vučićević-Trobok, J1
Gvozdenović, L1
Arndt, C1
Zambrowski, O1
Barbe, C1
Ducasse, A1
Andrijević Derk, B2
Benčić, G2
Corluka, V2
Zorić Geber, M2
Vatavuk, Z2
Wang, BZ1
Clark, B1
McKelvie, P1
Matthews, BJ1
Buttery, RG1
Chandra, A1
Prakash, P1
De Salvo, G1
Lotery, AJ1
Buyukyildiz, HZ1
Gulkilik, G1
Kumcuoglu, YZ1
Ossewaarde-van Norel, J1
Berg, EM1
Sijssens, KM1
Rothova, A1
Ascaso, FJ1
Rojo, M1
Minguez, E1
Cohen, SM1
Yang, SS1
Martínez-Castillo, S1
Gallego-Pinazo, R1
Díaz-Llopis, M1
SANTONI, A1
HATSUDA, T1
VARY, I1
PALFALVI, M1
Passemard, M1
Lafontaine, PO1
Creuzot-Garcher, C1
Morris, DS1
Severn, PS1
Smith, J1
Somner, JE1
Stannard, KP1
Cottrell, DG1
Mehra, KS1
Gupta, MK1
Campbell, DG1
Marmor, MF3
Maack, T1
Fujitani, A1
Hayasaka, S1
Kusaka, S1
Mano, T1
Ohashi, Y1
Althaus, C1
Sundmacher, R1
Edmunds, B1
Canning, CR1
Hammond, CJ1
Chauhan, DS1
Stanford, MS1
Snady-McCoy, L1
Krupin, T1
Wolfensberger, TJ1
Chiang, RK1
Takeuchi, A1
Leys, A1
Vandenberghe, P1
Neudorfer, M1
Leibovitch, I1
Goldstein, M1
Loewenstein, A1
Gonzalez, C1
Ravalico, G1
Battaglia Parodi, M1
Weene, LE1
Kita, M1
Gíslason, I1
Jónasson, F1
Stefánsson, E1
Tsuboi, S1
Pederson, JE1
Brockhurst, RJ1
Schepens, CL1
Okamura, ID1
Regan, CD1
McMeel, JW1
Hartley, RE1
Marsh, RJ1
Schwartz, A1

Trials

4 trials available for acetazolamide and Retinal Pigment Epithelial Detachment

ArticleYear
[Tonometric response to acetazolamide in patients with retinal detachment].
    Journal francais d'ophtalmologie, 2014, Volume: 37, Issue:2

    Topics: Acetazolamide; Epiretinal Membrane; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ophthal

2014
Subfoveal serous retinal detachment in patients with uveitic macular edema.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2011, Volume: 129, Issue:2

    Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Female; Foll

2011
The effect of prophylactic acetazolamide in patients undergoing extensive retinal detachment repair.
    Eye (London, England), 1996, Volume: 10 ( Pt 3)

    Topics: Acetazolamide; Female; Humans; Intraocular Pressure; Length of Stay; Male; Middle Aged; Ocular Hyper

1996
In office retinal detachment surgery: pneumatic retinopexy, a Rhode Island experience.
    Medicine and health, Rhode Island, 1999, Volume: 82, Issue:2

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Cryosurgery; Female;

1999

Other Studies

35 other studies available for acetazolamide and Retinal Pigment Epithelial Detachment

ArticleYear
Macular neurosensory retinal detachment associated with topiramate use.
    Archivos de la Sociedad Espanola de Oftalmologia, 2019, Volume: 94, Issue:12

    Topics: Acetazolamide; Adult; Antihypertensive Agents; Female; Fundus Oculi; Humans; Intracranial Hypertensi

2019
Medical therapy for bilateral uveal effusion syndrome in nanophthalmos.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2017, Volume: 52, Issue:6

    Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Benzophenones; Brom

2017
Ocular findings in patient with primary familial pulmonary hypertension.
    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2013, Volume: 10, Issue:1

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Familial Primary Pulmonary

2013
Medical therapy for uveal effusion syndrome.
    Eye (London, England), 2014, Volume: 28, Issue:8

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Antihypertensive Agents; Carbon

2014
Four quadrant sclerotomies for uveal effusion syndrome.
    Eye (London, England), 2015, Volume: 29, Issue:4

    Topics: Acetazolamide; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Choroid Diseases; Female; Hum

2015
Reply to: 'Four quadrant sclerotomies for uveal effusion syndrome'.
    Eye (London, England), 2015, Volume: 29, Issue:4

    Topics: Acetazolamide; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Choroid Diseases; Female; Hum

2015
Morning glory with serous macular detachment responds to oral acetazolamide.
    Eye (London, England), 2010, Volume: 24, Issue:11

    Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Macula Lu

2010
Early serous macular detachment after phacoemulsification surgery.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:11

    Topics: Acetazolamide; Cefuroxime; Female; Fluorescein Angiography; Humans; Macular Edema; Male; Middle Aged

2010
Diagnostic and therapeutic challenges.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:3

    Topics: Acetazolamide; Central Serous Chorioretinopathy; Female; Fluorescein Angiography; Glucocorticoids; H

2011
Early macular thickening versus pseudophakic cystoid macular edema.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:4

    Topics: Acetazolamide; Cefuroxime; Fluorescein Angiography; Humans; Macular Edema; Phacoemulsification; Post

2011
[Possibility of influencing the reabsorption of subretinal fluid in the preoperative phase of detachment by the administration of diamox].
    Annali di ottalmologia e clinica oculistica, 1957, Volume: 83, Issue:10

    Topics: Acetazolamide; Humans; Retina; Retinal Detachment; Subretinal Fluid; Vitreous Body

1957
[A CASE OF CHOROIDAL DETACHMENT AFTER FILTERING OPERATION].
    Nihon ganka kiyo, 1963, Volume: 14

    Topics: Acetazolamide; Atropine; Choroid; Choroid Diseases; Filtering Surgery; Glaucoma; Humans; Mydriatics;

1963
[DATA ON RARE FORMS OF CORNEAL TRANSPLANTATION].
    Szemeszet, 1964, Volume: 101

    Topics: Acetazolamide; Corneal Transplantation; Eye Diseases; Eye Injuries; Humans; Intraocular Pressure; Pi

1964
[Persistent foveal retinal detachment after successful rhegmatogenous retinal detachment surgery by scleral buckling].
    Journal francais d'ophtalmologie, 2007, Volume: 30, Issue:4

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cryotherapy; Humans; Male; Retinal Detachment;

2007
High altitude and retinal detachment.
    High altitude medicine & biology, 2007,Winter, Volume: 8, Issue:4

    Topics: Acetazolamide; Adult; Altitude; Altitude Sickness; Carbonic Anhydrase Inhibitors; Humans; Male; Moun

2007
RETINAL DETACHMENT AND GLAUCOMA.
    The British journal of ophthalmology, 1962, Volume: 46, Issue:12

    Topics: Acetazolamide; Child; Eye Injuries; Glaucoma; Glucocorticoids; Humans; Intraocular Pressure; Male; R

1962
Iris retraction associated with rhegmatogenous retinal detachment syndrome and hypotony. A new explanation.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:10

    Topics: Acetazolamide; Adult; Aged; Aqueous Humor; Female; Glaucoma; Humans; Intraocular Pressure; Iris; Iri

1984
Enhancement of retinal adhesion and subretinal fluid resorption by acetazolamide.
    Investigative ophthalmology & visual science, 1982, Volume: 23, Issue:1

    Topics: Acetazolamide; Adhesiveness; Animals; Anura; Dose-Response Relationship, Drug; Humans; Pigment Epith

1982
Concurrent acute angle-closure glaucoma, choroidal detachment and exudative retinal detachment in a patient with spontaneous carotid cavernous fistula.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1995, Volume: 209, Issue:4

    Topics: Acetazolamide; Acute Disease; Adrenergic beta-Antagonists; Arteriovenous Fistula; Carbonic Anhydrase

1995
Transient myopia after pars plana vitrectomy.
    Ophthalmic surgery and lasers, 1996, Volume: 27, Issue:1

    Topics: Acetazolamide; Adult; Humans; Intraocular Pressure; Male; Myopia; Remission, Spontaneous; Retinal De

1996
[Combination therapy of circumscribed choroid hemangioma in contralateral Sturge-Weber syndrome with acetazolamide and laser coagulation].
    Klinische Monatsblatter fur Augenheilkunde, 1996, Volume: 208, Issue:4

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Choroid Neoplasms; Combined Modality Therapy; F

1996
Pulmonary hypertension and diffuse macular edema responsive to acetazolamide.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:11

    Topics: Acetazolamide; Adult; Blood Pressure; Edema; Female; Fluorescein Angiography; Fundus Oculi; Humans;

1998
Marfan syndrome, lens subluxation, and open-angle glaucoma.
    Journal of glaucoma, 1999, Volume: 8, Issue:6

    Topics: Acetazolamide; Adult; Cataract Extraction; Drug Therapy, Combination; Female; Glaucoma, Open-Angle;

1999
Inhibition of membrane-bound carbonic anhydrase enhances subretinal fluid absorption and retinal adhesiveness.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2000, Volume: 238, Issue:1

    Topics: Absorption; Acetazolamide; Adhesiveness; Animals; Benzolamide; Carbonic Anhydrase Inhibitors; Carbon

2000
Serous macular detachments in a patient with IgM paraproteinemia: an optical coherence tomography study.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:6

    Topics: Acetazolamide; Aged; Diabetes Mellitus, Type 2; Diagnostic Techniques, Ophthalmological; Fluorescein

2001
Massive choroidal hemorrhage associated with low molecular weight heparin therapy.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2002, Volume: 13, Issue:3

    Topics: Acetazolamide; Aged; Aged, 80 and over; Angina, Unstable; Anticoagulants; Choroid Hemorrhage; Drug T

2002
[Serous retinal detachment. Value of acetazolamide].
    Journal francais d'ophtalmologie, 1992, Volume: 15, Issue:10

    Topics: Acetazolamide; Aging; Drug Evaluation; Female; Fluorescein Angiography; Humans; Macular Degeneration

1992
Exudative retinal detachment subsequent to retinal vein occlusion.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1992, Volume: 205, Issue:2

    Topics: Acetazolamide; Aged; Aged, 80 and over; Exudates and Transudates; Female; Fluorescein Angiography; F

1992
Cystoid macular edema after scleral buckling responsive to acetazolamide.
    Annals of ophthalmology, 1992, Volume: 24, Issue:11

    Topics: Acetazolamide; Cell Membrane; Fundus Oculi; Humans; Macular Edema; Male; Middle Aged; Postoperative

1992
Retinal adhesive force in living rabbit, cat, and monkey eyes. Normative data and enhancement by mannitol and acetazolamide.
    Investigative ophthalmology & visual science, 1992, Volume: 33, Issue:6

    Topics: Acetazolamide; Adhesiveness; Animals; Cats; Injections, Intravenous; Macaca mulatta; Mannitol; Rabbi

1992
Exudative retinal detachment in familial pulmonary hypertension.
    Acta ophthalmologica, 1991, Volume: 69, Issue:6

    Topics: Acetazolamide; Adult; Female; Fluorescein Angiography; Fundus Oculi; Humans; Hypertension, Pulmonary

1991
Experimental retinal detachment. X. Effect of acetazolamide on vitreous fluorescein disappearance.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:10

    Topics: Acetazolamide; Animals; Fluorescein; Fluoresceins; Macaca fascicularis; Retinal Detachment; Retinal

1985
Scleral buckling procedures. 8. Preoperative complications.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 74, Issue:6

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Anesthetics, Local; Choroid; Conjunctivitis; Dacryocysti

1965
An analysis of 13 cases of severe anterior chamber shallowing following retinal detachment surgery.
    Modern problems in ophthalmology, 1974, Volume: 12, Issue:0

    Topics: Acetazolamide; Anterior Chamber; Eye Diseases; Female; Fluorescein Angiography; Glaucoma; Gonioscopy

1974
Chronic open-angle glaucoma secondary to rhegmatogenous retinal detachment.
    American journal of ophthalmology, 1973, Volume: 75, Issue:2

    Topics: Acetazolamide; Adolescent; Adult; Betamethasone; Child; Cortisone; Electrocoagulation; Epinephrine;

1973