acetazolamide has been researched along with Pulmonary Hypertension in 36 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Excerpt | Relevance | Reference |
---|---|---|
"We tested the effect of acetazolamide on blood mechanical properties and pulmonary vascular resistance (PVR) during chronic hypoxia." | 7.78 | Acetazolamide and chronic hypoxia: effects on haemorheology and pulmonary haemodynamics. ( Brunet, J; Connes, P; Cymbalista, F; Favret, F; Levy, BI; Maignan, M; Marchant, D; Pichon, A; Quidu, P; Richalet, JP; Safeukui, I; Vilar, J, 2012) |
"Arrhythmias were rare and similar with all treatments." | 6.79 | Effect of oxygen and acetazolamide on nocturnal cardiac conduction, repolarization, and arrhythmias in precapillary pulmonary hypertension and sleep-disturbed breathing. ( Bloch, KE; Hasler, ED; Hildenbrand, FF; Keusch, S; Müller-Mottet, S; Schumacher, DS; Speich, R; Ulrich, S, 2014) |
"5%, 8 h/d and 6 d/week) and divided into hypoxia group and hypoxia plus acetazolamide (Acz) group (hypoxic rats were treated with ig acetazolamide (Acz) 80 mg x kg(-1) d(-1)) ." | 3.79 | [The selective dilatation effects of iptakalim on pulmonary arterioles in hypoxic pulmonary hypertensive rat]. ( Deng, HH; Duan, RF; Guo, YH; Han, WZ; Huang, JH; Liu, W; Wang, H; Zhang, YF, 2013) |
"We tested the effect of acetazolamide on blood mechanical properties and pulmonary vascular resistance (PVR) during chronic hypoxia." | 3.78 | Acetazolamide and chronic hypoxia: effects on haemorheology and pulmonary haemodynamics. ( Brunet, J; Connes, P; Cymbalista, F; Favret, F; Levy, BI; Maignan, M; Marchant, D; Pichon, A; Quidu, P; Richalet, JP; Safeukui, I; Vilar, J, 2012) |
"Arrhythmias were rare and similar with all treatments." | 2.79 | Effect of oxygen and acetazolamide on nocturnal cardiac conduction, repolarization, and arrhythmias in precapillary pulmonary hypertension and sleep-disturbed breathing. ( Bloch, KE; Hasler, ED; Hildenbrand, FF; Keusch, S; Müller-Mottet, S; Schumacher, DS; Speich, R; Ulrich, S, 2014) |
" The data show that a low prophylactic dosage of acetazolamide, but not gingko biloba, mitigates the early increase of PASP in a quick ascent profile." | 2.78 | Effect of acetazolamide and gingko biloba on the human pulmonary vascular response to an acute altitude ascent. ( Chen, J; Chen, Y; Hu, Y; Ke, T; Liu, M; Luo, W; Shen, X; Swenson, ER; Wang, J; Yang, Q; Zhang, W; Zhang, X; Zhao, F, 2013) |
" However, evidence indicates that reduced dosage schemes compared to the current recommendations are warranted." | 2.58 | Advances in the available non-biological pharmacotherapy prevention and treatment of acute mountain sickness and high altitude cerebral and pulmonary oedema. ( Balanos, GM; Imray, CHE; Joyce, KE; Lucas, SJE; Wright, AD, 2018) |
"Acute diarrhea was the most common ailment reported among the participants (18%), followed closely by musculoskeletal problems (17%)." | 1.56 | Morbidity Among Athletes Presenting for Medical Care During 3 Iterations of an Ultratrail Race in the Himalayas. ( Basyal, B; Dawadi, S; Subedi, Y, 2020) |
"Treatment with Acetazolamide provided quick recovery in the bilateral case, whereas the unilateral exudative detachment recovered without treatment after delivery." | 1.28 | Exudative retinal detachment in familial pulmonary hypertension. ( Gíslason, I; Jónasson, F; Stefánsson, E, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (25.00) | 18.7374 |
1990's | 2 (5.56) | 18.2507 |
2000's | 2 (5.56) | 29.6817 |
2010's | 18 (50.00) | 24.3611 |
2020's | 5 (13.89) | 2.80 |
Authors | Studies |
---|---|
Luks, AM | 2 |
Hackett, PH | 1 |
Hundt, N | 1 |
Apel, C | 1 |
Bertsch, D | 1 |
Cerfontaine, C | 1 |
van der Giet, M | 1 |
van der Giet, S | 1 |
Graß, M | 1 |
Haunolder, M | 1 |
Heussen, NM | 1 |
Jäger, J | 1 |
Kühn, C | 1 |
Morrison, A | 1 |
Museo, S | 1 |
Timmermann, L | 1 |
Wernitz, K | 1 |
Gieseler, U | 1 |
Küpper, T | 1 |
Swenson, ER | 2 |
Dawadi, S | 1 |
Basyal, B | 1 |
Subedi, Y | 1 |
Deniz, S | 1 |
Uysal, TK | 1 |
Capasso, C | 1 |
Supuran, CT | 1 |
Ozensoy Guler, O | 1 |
Davis, C | 1 |
Hackett, P | 1 |
Parise, I | 1 |
Nieto Estrada, VH | 2 |
Molano Franco, D | 2 |
Medina, RD | 1 |
Gonzalez Garay, AG | 2 |
Martí-Carvajal, AJ | 2 |
Arevalo-Rodriguez, I | 3 |
Basnyat, B | 1 |
Hofmeyr, R | 1 |
Tölken, G | 1 |
De Decker, R | 1 |
Simancas-Racines, D | 1 |
Osorio, D | 1 |
Franco, JV | 1 |
Xu, Y | 1 |
Hidalgo, R | 1 |
Joyce, KE | 1 |
Lucas, SJE | 1 |
Imray, CHE | 1 |
Balanos, GM | 1 |
Wright, AD | 1 |
Li, Y | 1 |
Zhang, Y | 2 |
Ke, T | 1 |
Wang, J | 1 |
Zhang, X | 1 |
Hu, Y | 1 |
Chen, Y | 1 |
Liu, M | 1 |
Zhang, W | 1 |
Zhao, F | 1 |
Shen, X | 1 |
Yang, Q | 1 |
Chen, J | 1 |
Luo, W | 1 |
Huang, JH | 1 |
Han, WZ | 1 |
Zhang, YF | 1 |
Duan, RF | 1 |
Deng, HH | 1 |
Guo, YH | 1 |
Liu, W | 1 |
Wang, H | 1 |
Ulrich, S | 2 |
Keusch, S | 2 |
Hildenbrand, FF | 2 |
Lo Cascio, C | 1 |
Huber, LC | 1 |
Tanner, FC | 1 |
Speich, R | 2 |
Bloch, KE | 2 |
Schumacher, DS | 1 |
Müller-Mottet, S | 1 |
Hasler, ED | 1 |
O'Hara, R | 1 |
Serres, J | 1 |
Dodson, W | 1 |
Bruce, W | 1 |
Ordway, J | 1 |
Powell, E | 1 |
Wade, M | 1 |
Lüscher, TF | 1 |
Bultas, J | 1 |
Richalet, JP | 3 |
Larmignat, P | 1 |
Poitrine, E | 1 |
Letournel, M | 1 |
Canouï-Poitrine, F | 1 |
Pichon, A | 1 |
Connes, P | 1 |
Quidu, P | 1 |
Marchant, D | 1 |
Brunet, J | 1 |
Levy, BI | 1 |
Vilar, J | 1 |
Safeukui, I | 1 |
Cymbalista, F | 1 |
Maignan, M | 2 |
Favret, F | 1 |
Jones, BE | 1 |
Stokes, S | 1 |
McKenzie, S | 1 |
Nilles, E | 1 |
Stoddard, GJ | 1 |
SCHWARTZ, WB | 1 |
RELMAN, AS | 1 |
LEAF, A | 1 |
TAYMOR, RC | 1 |
BRICAUD, H | 2 |
BROUSTET, P | 2 |
TAQUINI, AC | 1 |
RONCORONI, AJ | 1 |
ARAMENDIA, P | 1 |
ROS, AM | 1 |
BROMBERG-SZNEK, S | 1 |
RAFALOWICZ, A | 1 |
AGOTE POVEDA, IP | 1 |
VILLANUEVA EDO, A | 1 |
MUETZ, R | 1 |
Rivera-Ch, M | 2 |
León-Velarde, F | 2 |
Huicho, L | 1 |
Privat, C | 1 |
Pham, I | 1 |
Macarlupu, JL | 1 |
Petitjean, O | 1 |
Meyers, D | 1 |
Hammond, CJ | 1 |
Chauhan, DS | 1 |
Stanford, MS | 1 |
Gíslason, I | 1 |
Jónasson, F | 1 |
Stefánsson, E | 1 |
Kühn, P | 1 |
Probst, P | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Multicenter Randomized Double-Blind Control Trial Evaluating the Utility of Continuous Positive Airway Pressure (CPAP) in the Treatment of High Altitude Pulmonary Edema (HAPE)[NCT04186598] | 264 participants (Anticipated) | Interventional | 2020-01-20 | Recruiting | |||
Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension (CSRPH)[NCT01427192] | Phase 2 | 23 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
Controlled Hyperventilation as Prophylaxis for Acute Mountain Sickness: A Randomized Controlled Trial[NCT02972411] | 30 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
Study of Periodic Breathing in Healthy Humans[NCT02201875] | 120 participants (Anticipated) | Observational | 2014-09-30 | Not yet recruiting | |||
Calibration of a New Reflectance Oximeter.[NCT02842255] | 10 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
Multicentric Evaluation of the Impact on Hypoxia Sensitivity of Patients With COVID-19[NCT05167357] | 90 participants (Anticipated) | Interventional | 2021-03-18 | Recruiting | |||
Hypoventilation and High Altitude Chronic Polycythemia: Acetazolamide as a Possible Treatment[NCT00424970] | Phase 4 | 55 participants (Anticipated) | Interventional | 2007-01-31 | Completed | ||
Randomized Controlled Trial of N-acetylcysteine and Acetazolamide in Treatment of Chronic Mountain Sickness[NCT01187108] | Phase 1/Phase 2 | 85 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
11 reviews available for acetazolamide and Pulmonary Hypertension
Article | Year |
---|---|
Medical Conditions and High-Altitude Travel.
Topics: Acetazolamide; Altitude; Altitude Sickness; Brain Edema; Chronic Disease; Dexamethasone; Female; Hum | 2022 |
COVID-19 Lung Injury and High-Altitude Pulmonary Edema. A False Equation with Dangerous Implications.
Topics: Acetazolamide; Altitude Sickness; Betacoronavirus; Carbonic Anhydrase Inhibitors; Coronavirus Infect | 2020 |
Advances in the Prevention and Treatment of High Altitude Illness.
Topics: Acetazolamide; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Anticonvulsants; Brain Edema; | 2017 |
Travelling safely to places at high altitude - Understanding and preventing altitude illness.
Topics: Acclimatization; Acetazolamide; Altitude; Altitude Sickness; Anticonvulsants; Antiemetics; Calcium C | 2017 |
Interventions for preventing high altitude illness: Part 1. Commonly-used classes of drugs.
Topics: Acetazolamide; Adolescent; Adult; Aged; Altitude Sickness; Brain Edema; Budesonide; Carbonic Anhydra | 2017 |
Interventions for treating acute high altitude illness.
Topics: Acetazolamide; Acute Disease; Adolescent; Adult; Altitude Sickness; Amines; Anticonvulsants; Atmosph | 2018 |
Advances in the available non-biological pharmacotherapy prevention and treatment of acute mountain sickness and high altitude cerebral and pulmonary oedema.
Topics: Acetazolamide; Acute Disease; Altitude; Altitude Sickness; Animals; Brain Edema; Calcium Channel Blo | 2018 |
Research advances in pathogenesis and prophylactic measures of acute high altitude illness.
Topics: Acetazolamide; Acute Disease; Altitude Sickness; Calcium Channel Blockers; Carbonic Anhydrase Inhibi | 2018 |
Interventions for preventing high altitude illness: Part 3. Miscellaneous and non-pharmacological interventions.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Ginkgo biloba; Humans; Hypertension, Pulmonary; Medro | 2019 |
The use of dexamethasone in support of high-altitude ground operations and physical performance: review of the literature.
Topics: Acclimatization; Acetazolamide; Altitude; Altitude Sickness; Carbonic Anhydrase Inhibitors; Cognitio | 2014 |
Treatment of chronic mountain sickness: critical reappraisal of an old problem.
Topics: Acclimatization; Acetazolamide; Altitude; Altitude Sickness; Angiotensin-Converting Enzyme Inhibitor | 2007 |
4 trials available for acetazolamide and Pulmonary Hypertension
Article | Year |
---|---|
Effect of acetazolamide and gingko biloba on the human pulmonary vascular response to an acute altitude ascent.
Topics: Acetazolamide; Acute Disease; Adolescent; Altitude Sickness; Antihypertensive Agents; Double-Blind M | 2013 |
Effect of nocturnal oxygen and acetazolamide on exercise performance in patients with pre-capillary pulmonary hypertension and sleep-disturbed breathing: randomized, double-blind, cross-over trial.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Combined Modality Therapy; C | 2015 |
Effect of oxygen and acetazolamide on nocturnal cardiac conduction, repolarization, and arrhythmias in precapillary pulmonary hypertension and sleep-disturbed breathing.
Topics: Acetazolamide; Administration, Oral; Aged; Arrhythmias, Cardiac; Carbonic Anhydrase Inhibitors; Cros | 2014 |
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu | 2008 |
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu | 2008 |
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu | 2008 |
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu | 2008 |
21 other studies available for acetazolamide and Pulmonary Hypertension
Article | Year |
---|---|
Variables Influencing the Pressure and Volume of the Pulmonary Circulation as Risk Factors for Developing High Altitude Pulmonary Edema (HAPE).
Topics: Acetazolamide; Aged; Altitude; Altitude Sickness; Humans; Hypertension, Pulmonary; Pulmonary Circula | 2022 |
Morbidity Among Athletes Presenting for Medical Care During 3 Iterations of an Ultratrail Race in the Himalayas.
Topics: Acetazolamide; Adult; Altitude; Altitude Sickness; Athletic Injuries; Carbonic Anhydrase Inhibitors; | 2020 |
Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection?
Topics: Acetazolamide; Acid-Base Equilibrium; Altitude Sickness; Anticonvulsants; Antiviral Agents; Bicarbon | 2021 |
Acute high-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Chemoprevention; Diuretics; Humans; Hypertension, Pul | 2017 |
[The selective dilatation effects of iptakalim on pulmonary arterioles in hypoxic pulmonary hypertensive rat].
Topics: Acetazolamide; Animals; Arterioles; Hypertension, Pulmonary; Hypoxia; Male; Propylamines; Pulmonary | 2013 |
Pulmonary embolism and pulmonary hypertension: two issues often neglected in cardiology.
Topics: Acetazolamide; Antihypertensive Agents; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Oxygen; | 2015 |
[Mountain sickness].
Topics: Acetazolamide; Acute Disease; Adaptation, Physiological; Altitude; Altitude Sickness; Brain Edema; C | 2015 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte | 2012 |
Acetazolamide and chronic hypoxia: effects on haemorheology and pulmonary haemodynamics.
Topics: Acetazolamide; Altitude Sickness; Animals; Blood Viscosity; Blood Volume; Carbonic Anhydrase Inhibit | 2012 |
Management of high altitude pulmonary edema in the Himalaya: a review of 56 cases presenting at Pheriche medical aid post (4240 m).
Topics: Acetazolamide; Altitude Sickness; Dexamethasone; Emergency Treatment; Female; Humans; Hypertension, | 2013 |
Oral administration of a potent carbonic anhydrase inhibitor (diamox). III. Its use as a diuretic in patients with severe congestive heart failure due to cor pulmonale.
Topics: Acetazolamide; Administration, Oral; Carbonic Anhydrase Inhibitors; Chronic Disease; Diuretics; Hear | 1955 |
Mechanism and use of diamox in heart failure and cor pulmonale.
Topics: Acetazolamide; Cardiotonic Agents; Diuretics; Heart Arrest; Heart Failure; Hydro-Lyases; Hypertensio | 1955 |
[Acetazolamide in the treatment of chronic pulmonary heart disease].
Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease | 1956 |
[Acetazolamide in the treatment of chronic pulmonary heart disease].
Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease | 1956 |
[Acetazolamide in the treatment of chronic pulmonary heart disease].
Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease | 1956 |
[Acetazolamide in the treatment of chronic pulmonary heart disease].
Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease | 1956 |
Sensitivity of respiratory center to carbon dioxide in emphysema and cor pulmonale: effects of carbonic anhydrase inhibition.
Topics: Acetazolamide; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chronic Disease; | 1957 |
[Effects of diamox in cor pulmonale].
Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease | 1958 |
[Acetazolamide in the treatment of chronic cor pulmonale].
Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease | 1958 |
[PATHOPHYSIOLOGY AND THERAPY OF PULMONARY EMPHYSEMA WITH RESPIRATORY ACIDOSIS AND COR PULMONALE].
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Anti-Bacterial Agents; Cardiac Glycosides; Exercise | 1963 |
Acetazolamide in the mountains.
Topics: Acetazolamide; Altitude Sickness; Humans; Hypertension, Pulmonary; Hypoxia | 1981 |
Pulmonary hypertension and diffuse macular edema responsive to acetazolamide.
Topics: Acetazolamide; Adult; Blood Pressure; Edema; Female; Fluorescein Angiography; Fundus Oculi; Humans; | 1998 |
Exudative retinal detachment in familial pulmonary hypertension.
Topics: Acetazolamide; Adult; Female; Fluorescein Angiography; Fundus Oculi; Humans; Hypertension, Pulmonary | 1991 |
[Acid-base equilibrium and blood gas analysis in clinical cardiology].
Topics: Acetazolamide; Acid-Base Equilibrium; Bicarbonates; Blood Gas Analysis; Body Weight; Diagnosis, Diff | 1970 |