acetazolamide and Pseudotumor Cerebri studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Pseudotumor Cerebri: A condition marked by raised intracranial pressure and characterized clinically by HEADACHES; NAUSEA; PAPILLEDEMA, peripheral constriction of the visual fields, transient visual obscurations, and pulsatile TINNITUS. OBESITY is frequently associated with this condition, which primarily affects women between 20 and 44 years of age. Chronic PAPILLEDEMA may lead to optic nerve injury (see OPTIC NERVE DISEASES) and visual loss (see BLINDNESS).

Research Excerpts

Excerpt	Relevance	Reference
" Currently, no standardized treatment guidelines are available and the current management focuses on weight loss and acetazolamide use."	9.41	Should topiramate be initial therapy in the management of idiopathic intracranial hypertension?: A literature review. ( Goyal, A; Zarroli, K, 2023)
"Patients underwent weight loss and treatment with acetazolamide during a 24-week period."	9.08	The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri) ( Johnson, LN; Krohel, GB; Madsen, RW; March, GA, 1998)
" The information regarding fetal effects of acetazolamide use during pregnancy and lactation is sparse."	9.05	Brief report: Metabolic acidosis in newborn infants following maternal use of acetazolamide during pregnancy. ( Hussain, N; Ibrahim, A, 2020)
"Although laboratory finding of metabolic acidosis is common among patients with idiopathic intracranial hypertension treated with acetazolamide, it is not correlated with clinics."	8.84	The manifestations of metabolic acidosis during acetazolamide treatment in a cohort of pediatric idiopathic intracranial hypertension. ( Barnoy, N; Bulkowstein, Y; Gilboa, T; Nitzan-Luques, A; Reif, S; Schnapp, A; Volovesky, O, 2024)
"Acetazolamide (ACZ) lowers intraocular pressure (IOP), acutely in normal eyes and both acutely and chronically in eyes with glaucoma, and cerebrospinal fluid pressure (CSFp), chronically in patients with idiopathic intracranial hypertension (IIH)."	7.91	The Effect of Acetazolamide and Weight Loss on Intraocular Pressure in Idiopathic Intracranial Hypertension Patients. ( Banik, R; Garvin, MK; Kupersmith, MJ; Wang, JK, 2019)
" Acetazolamide is widely used as the initial treatment option; however, previously published evidence suggests that this drug may also increase the risk of nephrolithiasis."	7.83	Acetazolamide-Induced Nephrolithiasis in Idiopathic Intracranial Hypertension Patients. ( Au, JN; Huisingh, C; McGwin, G; Tanne, E; Waslo, CS, 2016)
"There is no convincing evidence for an adverse effect for acetazolamide use in human pregnancy, even when prescribed prior to the 13th week of gestation."	7.79	The use of acetazolamide during pregnancy in intracranial hypertension patients. ( Falardeau, J; Golden, S; Lobb, BM; Maxfield, SD; Tanne, E, 2013)
"To describe the pregnancy outcomes after the use of acetazolamide in pregnant patients with idiopathic intracranial hypertension (IIH)."	7.73	The use of acetazolamide in idiopathic intracranial hypertension during pregnancy. ( Capozzoli, T; Falardeau, J; Kardon, RH; Lee, AG; Pless, M; Wall, M, 2005)
"To describe the hemodynamic effect of oral acetazolamide administration on ocular perfusion in a patient with pseudotumor cerebri associated with Crohn disease."	7.71	Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease. ( Arnaud, B; Greenfield, DS; Harris, A; Pageaux, GP; Veyrac, M; Villain, MA, 2002)
"To describe a case of pseudotumor cerebri associated with the administration of intermediate-dose cytarabine."	7.70	Pseudotumor cerebri secondary to intermediate-dose cytarabine HCl. ( Fort, JA; Smith, LD, 1999)
"The purpose of this study was to investigate the efficacy of combined therapy with acetazolamide and furosemide in normalizing intracranial pressure in children with pseudotumor cerebri."	7.69	Childhood pseudotumor cerebri: clinical and intracranial pressure response to acetazolamide and furosemide treatment in a case series. ( Schoeman, JF, 1994)
"We treated four patients who had acute, severe visual loss associated with pseudotumor cerebri with intravenous methylprednisolone (250 mg four times per day) for five days followed by an oral taper, in combination with acetazolamide and ranitidine."	7.69	High-dose methylprednisolone and acetazolamide for visual loss in pseudotumor cerebri. ( Glaser, JS; Liu, GT; Schatz, NJ, 1994)
"Treatment with acetazolamide for pseudotumor cerebri (PTC) in a renal transplant patient led to an acute, but reversible deterioration in renal function."	7.68	Deteriorating renal function with acetazolamide in a renal transplant patient with pseudotumor cerebri. ( Chagnac, A; Floru, S; Gafter, U; Korzets, A; Zevin, D, 1993)
"Acetazolamide is a carbonic anhydrase inhibitor that is used to treat idiopathic intracranial hypertension, glaucoma, and epilepsy."	5.43	Possible association between acetazolamide administration during pregnancy and multiple congenital malformations. ( Al-Jobair, AM; Al-Saleem, AI, 2016)
" Currently, no standardized treatment guidelines are available and the current management focuses on weight loss and acetazolamide use."	5.41	Should topiramate be initial therapy in the management of idiopathic intracranial hypertension?: A literature review. ( Goyal, A; Zarroli, K, 2023)
"Frisén score fails to reflect the photographic area and OCT volume of papilledema after treatment with acetazolamide."	5.27	The Relationship Between Optic Disc Volume, Area, and Frisén Score in Patients With Idiopathic Intracranial Hypertension. ( Blanchard, LM; Feldon, SE; Fischer, WS; Hollar, RA; Sheils, CR, 2018)
" The Idiopathic Intracranial Hypertension Treatment Trial, a large, randomized, collaborative clinical trial, evaluated the efficacy of acetazolamide with weight loss versus placebo with weight loss in participants."	5.22	Pseudotumor cerebri: What We Have Learned from the Idiopathic Intracranial Hypertension Treatment Trial. ( Johnson, LN; Johnson, MA; Krohel, GB; Thakore, RV, 2016)
"To assess treatment efficacy using spectral-domain (SD) optical coherence tomography (OCT) measurements of papilledema in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT), which evaluated the effects of acetazolamide and weight management and of placebo and weight management in eyes with mild visual loss."	5.20	Papilledema Outcomes from the Optical Coherence Tomography Substudy of the Idiopathic Intracranial Hypertension Treatment Trial. ( , 2015)
" The Idiopathic Intracranial Hypertension Treatment Trial was an adult, multicenter study that examined the use of acetazolamide and weight loss on the course of PIH."	5.12	Pediatric Intracranial Hypertension: A Spotlight on Imaging, the Idiopathic Intracranial Hypertension Treatment Trial, and COVID-19 Associated Cases. ( Aylward, SC; Brun, BN, 2021)
"Patients underwent weight loss and treatment with acetazolamide during a 24-week period."	5.08	The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri) ( Johnson, LN; Krohel, GB; Madsen, RW; March, GA, 1998)
" The information regarding fetal effects of acetazolamide use during pregnancy and lactation is sparse."	5.05	Brief report: Metabolic acidosis in newborn infants following maternal use of acetazolamide during pregnancy. ( Hussain, N; Ibrahim, A, 2020)
" Treatment options are serial lumbar punctures combined with body weight reduction as well as medication with carbonic anhydrase inhibitors, such as acetazolamide and topiramate or diuretic therapy with furosemide."	4.91	[Characteristic neurological features, differential diagnostic criteria and medicinal treatment of idiopathic intracranial hypertension]. ( Nacimiento, W; Willenborg, KD, 2015)
"Although laboratory finding of metabolic acidosis is common among patients with idiopathic intracranial hypertension treated with acetazolamide, it is not correlated with clinics."	4.84	The manifestations of metabolic acidosis during acetazolamide treatment in a cohort of pediatric idiopathic intracranial hypertension. ( Barnoy, N; Bulkowstein, Y; Gilboa, T; Nitzan-Luques, A; Reif, S; Schnapp, A; Volovesky, O, 2024)
"This open-label, single-center pilot study suggests that GLP-1-RAs are an effective and safe treatment option for achieving significant weight loss with a favorable effect on headache, leading to reduced acetazolamide dosage in pwIIH."	4.31	Treatment with GLP-1 receptor agonists is associated with significant weight loss and favorable headache outcomes in idiopathic intracranial hypertension. ( Bsteh, G; Harreiter, J; Itariu, B; Krajnc, N; Macher, S; Marik, W; Michl, M; Novak, K; Pemp, B; Wöber, C, 2023)
"VSS is an effective and safe procedure resulting in significant improvement of headaches, visual impairment, dizziness, and tinnitus, acetazolamide and topiramate usage were lower after VSS in patients with IIH."	4.12	Dural Venous Sinus Stenting in Idiopathic Intracranial Hypertension: A National Database Study of 541 Patients. ( Kan, P; Lall, R; Nia, AM; Srinivasan, VM, 2022)
"Acetazolamide (ACZ) lowers intraocular pressure (IOP), acutely in normal eyes and both acutely and chronically in eyes with glaucoma, and cerebrospinal fluid pressure (CSFp), chronically in patients with idiopathic intracranial hypertension (IIH)."	3.91	The Effect of Acetazolamide and Weight Loss on Intraocular Pressure in Idiopathic Intracranial Hypertension Patients. ( Banik, R; Garvin, MK; Kupersmith, MJ; Wang, JK, 2019)
" The most common symptom was headache (69%) and acetazolamide was the most used medication (69%)."	3.88	Pseudotumor cerebri in childhood and adolescence: data from a specialized service. ( Balbi, GGM; Fraga, MM; Len, CA; Matas, SL; Sousa, IO; Terreri, MT, 2018)
" Acetazolamide is widely used as the initial treatment option; however, previously published evidence suggests that this drug may also increase the risk of nephrolithiasis."	3.83	Acetazolamide-Induced Nephrolithiasis in Idiopathic Intracranial Hypertension Patients. ( Au, JN; Huisingh, C; McGwin, G; Tanne, E; Waslo, CS, 2016)
" Following lumbar puncture with opening pressure of 350 mmHg, a diagnosis of pseudotumor cerebri was made and treatment with acetazolamide was started."	3.79	Unilateral papilledema in pseudotumor cerebri. ( Brosh, K; Strassman, I, 2013)
"There is no convincing evidence for an adverse effect for acetazolamide use in human pregnancy, even when prescribed prior to the 13th week of gestation."	3.79	The use of acetazolamide during pregnancy in intracranial hypertension patients. ( Falardeau, J; Golden, S; Lobb, BM; Maxfield, SD; Tanne, E, 2013)
" The authors present 2 patients with Alagille syndrome who, before the age of 3 years old, developed idiopathic intracranial hypertension with documented increased intracranial pressure by lumbar puncture and papilledema, which was responsive to acetazolamide."	3.76	Idiopathic intracranial hypertension in two patients with Alagille syndrome. ( Furuya, KN; Mouzaki, M; Nichter, C; Qureshi, M; Rountree, B, 2010)
" The diagnosis of a pseudotumor cerebri, secondary to Behçet disease was raised and the patient was treated with colchicine and acetazolamide."	3.76	[Pseudotumor cerebri secondary to Behçet disease. Report of one case]. ( Castiglione, E; Durán, J; Eymin, G; Gutiérrez, MA; Jacobelli, S; Jurado, M; Valenzuela, R, 2010)
" One child with PTC demonstrated improvement in visual acuity and optic nerve appearance after acetazolamide and weight loss therapy."	3.74	Pseudotumor cerebri in children with Down syndrome. ( Bradfield, YS; Esmaili, N, 2007)
"To describe the pregnancy outcomes after the use of acetazolamide in pregnant patients with idiopathic intracranial hypertension (IIH)."	3.73	The use of acetazolamide in idiopathic intracranial hypertension during pregnancy. ( Capozzoli, T; Falardeau, J; Kardon, RH; Lee, AG; Pless, M; Wall, M, 2005)
" This was managed non-operatively with lumbar cerebrospinal fluid tap, weight reduction, nicotinic acid and acetazolamide."	3.73	Non-operative management of benign intracranial hypertension presenting with complete visual loss and deafness. ( Idowu, OE; Malomo, AO; Nwaorgu, OG; Oluleye, TS; Shokunbi, MT, 2006)
"To describe the hemodynamic effect of oral acetazolamide administration on ocular perfusion in a patient with pseudotumor cerebri associated with Crohn disease."	3.71	Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease. ( Arnaud, B; Greenfield, DS; Harris, A; Pageaux, GP; Veyrac, M; Villain, MA, 2002)
"Tetracyclines have long been recognized as a cause of pseudotumor cerebri in adults, but the role of tetracyclines in the pediatric age group has not been well characterized in the literature and there have been few reported cases."	3.70	Pediatric tetracycline-induced pseudotumor cerbri. ( Buncic, JR; Quinn, AG; Singer, SB, 1999)
"To describe a case of pseudotumor cerebri associated with the administration of intermediate-dose cytarabine."	3.70	Pseudotumor cerebri secondary to intermediate-dose cytarabine HCl. ( Fort, JA; Smith, LD, 1999)
"Idiopathic intracranial hypertension (IIH, pseudotumor cerebri) was diagnosed in 4 patients who had been treated with tetracycline."	3.69	[Idiopathic intracranial hypertension and tetracycline]. ( Schwartz, M; Sharf, B; Sierpinski-Barth, J; Weller, B, 1994)
"The purpose of this study was to investigate the efficacy of combined therapy with acetazolamide and furosemide in normalizing intracranial pressure in children with pseudotumor cerebri."	3.69	Childhood pseudotumor cerebri: clinical and intracranial pressure response to acetazolamide and furosemide treatment in a case series. ( Schoeman, JF, 1994)
"We treated four patients who had acute, severe visual loss associated with pseudotumor cerebri with intravenous methylprednisolone (250 mg four times per day) for five days followed by an oral taper, in combination with acetazolamide and ranitidine."	3.69	High-dose methylprednisolone and acetazolamide for visual loss in pseudotumor cerebri. ( Glaser, JS; Liu, GT; Schatz, NJ, 1994)
"Treatment with acetazolamide for pseudotumor cerebri (PTC) in a renal transplant patient led to an acute, but reversible deterioration in renal function."	3.68	Deteriorating renal function with acetazolamide in a renal transplant patient with pseudotumor cerebri. ( Chagnac, A; Floru, S; Gafter, U; Korzets, A; Zevin, D, 1993)
" The course was complicated by superior sagittal sinus thrombosis which we believe to be related to acetazolamide therapy."	3.66	Benign intracranial hypertension, monoclonal gammopathy, and superior sagittal sinus thrombosis. ( Davis, CE; Gilman, JK; Hibri, N; Smith, CH, 1983)
"In the IIHTT, subjects were randomly assigned to placebo-plus-diet or maximally tolerated dosage of acetazolamide-plus-diet."	2.84	The Longitudinal Idiopathic Intracranial Hypertension Trial: Outcomes From Months 6-12. ( Auinger, P; Kupersmith, MJ; Moss, EA; Moss, HE; Thurtell, MJ; Wall, M, 2017)
"To examine the tolerability and adverse events reported in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT)."	2.82	Safety and Tolerability of Acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial. ( Friedman, DI; Irrcher, I; McDermott, MP; Patel, AD; ten Hove, MW; Wall, M, 2016)
"Acetazolamide is a common treatment but has never been examined in a randomised controlled trial."	2.76	A randomised controlled trial of treatment for idiopathic intracranial hypertension. ( Ball, AK; Burdon, MA; Clarke, CE; Davies, MB; Furmston, A; Howell, S; Howman, A; Jacks, AS; Lawden, M; Matthews, T; Sharrack, B; Sinclair, AJ; Sivaguru, A; Wheatley, K, 2011)
"Prominent weight loss was recorded in the topiramate group."	2.73	Treatment of idiopathic intracranial hypertension: topiramate vs acetazolamide, an open-label study. ( Akyürekli, O; Celebisoy, N; Gökçay, F; Sirin, H, 2007)
"Parents of school-age children with idiopathic intracranial hypertension were asked to fill out a questionnaire and to rank the child's behavioral patterns before and after the diagnosis and treatment of the disease."	2.73	Behavioral disorders in children with idiopathic intracranial hypertension. ( Leiba, H; Margalit, D; Parness-Yossifon, R; Pollack, A, 2008)
"The headache associated with idiopathic intracranial hypertension frequently has a migrainous phenotype."	2.72	Diagnosis and treatment of idiopathic intracranial hypertension. ( Hoffmann, J; Raoof, N, 2021)
"The acetazolamide (AZA) test is a well-accepted method for measuring the vascular reactivity of the cerebral arteries."	2.70	Cerebrovascular reactivity in patients under long-term acetazolamide treatment. ( Gadot, N; Kesler, A; Lampl, Y; Lorberboyn, M; Sadeh, M, 2002)
"Symptomatic treatment of headache is recommended."	2.61	[Idiopathic intracranial hypertension - Swedish consensus guidelines]. ( Gustavsson, B; Hellgren, K; Lundvall, M; Nilsson Remahl, I; Söderman, M; Sundholm, A; Träisk, F, 2019)
"Idiopathic intracranial hypertension is a vision-threatening disorder that predominantly affects obese women of childbearing age."	2.58	An update of idiopathic intracranial hypertension. ( Cestari, DM; Madriz Peralta, G, 2018)
"Prior to the IIHTT, clinicians managed idiopathic intracranial hypertension based on data from small, unmasked trials, expert opinion, and clinical experience."	2.55	The Idiopathic Intracranial Hypertension Treatment Trial: A Review of the Outcomes. ( Friedman, DI; Smith, SV, 2017)
"Idiopathic intracranial hypertension is characterized by signs and symptoms of raised intracranial pressure with no established pathogenesis."	2.55	[Idiopathic intracranial hypertension]. ( Bäuerle, J; Egger, K; Harloff, A, 2017)
"Obesity is an important risk factor for primary and secondary PTC in post-pubertal children."	2.53	Pediatric pseudotumor cerebri. ( Phillips, PH; Rook, BS, 2016)
"In high-pressure hydrocephalus, the volume of the CSF is increased, resulting either from increased production or reduced absorption."	2.48	[Headache from increased cerebrospinal fluid pressure]. ( Göbel, C; Göbel, H; Heinze, A, 2012)
"Some theories - such as the dural sinus stenosis theory - seem to ignore the relationship with weight gain; others have proposed a direct link between obesity and raised intracranial pressure through a specific fat distribution in the body; others through the production of lipokines; and yet others have suggested a converse causation with raised intracranial pressure giving rise to obesity."	2.47	The syndrome of pseudotumour cerebri and idiopathic intracranial hypertension. ( Fraser, C; Plant, GT, 2011)
"Although the demographics of pediatric idiopathic intracranial hypertension have been well described, the best approaches to its management are less well defined."	2.44	Advances in evaluation and management of pediatric idiopathic intracranial hypertension. ( Hutcheson, KA; Wolf, A, 2008)
"Pseudotumor cerebri is an unusual presentation of Lyme disease."	2.40	Pseudotumor cerebri in Lyme disease: a case report and literature review. ( Kan, L; Maytal, J; Sood, SK, 1998)
"This retrospective single-center study evaluated the change in required dosage of acetazolamide and topiramate before and after dural venous sinus stent placement (VSSP) for idiopathic intracranial hypertension (IIH)."	1.91	Dural Venous Sinus Stent Placement Reduces Dosage Requirements for Carbonic Anhydrase Inhibitors in Patients with Idiopathic Intracranial Hypertension. ( Martin, J; Sanborn, MR, 2023)
"Acetazolamide therapy was started, and papilledema in both eyes resolved within weeks."	1.72	Recurrent Intracranial Hypertension in a Toddler with Graves' Disease. ( de Bruin, C; Notting, IC; Peeters-Scholte, CMPCD; Vuijk, FA, 2022)
"Although weight gain is expected in pregnancy, excessive weight gain may exacerbate IIH and increase maternal and fetal complications; evidence-based recommendations for non-IIH pregnancies may help in guiding optimal gestational weight gain."	1.72	Managing idiopathic intracranial hypertension in pregnancy: practical advice. ( Abbott, S; Mollan, SP; Sinclair, AJ; Tahrani, AA; Thaller, M; Wakerley, BR, 2022)
"We sought to characterize this bias for idiopathic intracranial hypertension (IIH) and evaluate strategies to reduce it."	1.72	Predictive Value of International Classification of Diseases Codes for Idiopathic Intracranial Hypertension in a University Health System. ( Khushzad, F; Kumar, R; Moss, HE; Muminovic, I, 2022)
" IOPs preoperatively and postoperatively were recorded along with the acetazolamide dosage and whether there was evidence of posterior scleral or globe indentation on preoperative MRI."	1.72	The Effect of Optic Nerve Sheath Fenestration on Intraocular Pressure in Patients With Idiopathic Intracranial Hypertension. ( Ford, WC; Mancini, R; Mullen, M; Scofield-Kaplan, SM, 2022)
"A robust predictor of visual outcome in idiopathic intracranial hypertension (IIH) would be useful in management, but there is limited information on this point."	1.51	Visual Field Mean Deviation at Diagnosis of Idiopathic Intracranial Hypertension Predicts Visual Outcome. ( Cornblath, WT; De Lott, L; Mikkilineni, S; Trobe, JD, 2019)
"He had bilateral sixth nerve palsy worse on the left eye and bilateral hypometric saccade."	1.51	Co-occurrence of acute ophthalmoplegia (without ataxia) and idiopathic intracranial hypertension. ( Mohamad, NF; Singh, S; Yeak, J; Zahari, M, 2019)
"Patients with idiopathic intracranial hypertension commonly present with a headache, transient visual obscurations, and intracranial noises with some cranial nerves occasionally involved, most commonly CN VI."	1.51	Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report. ( Berry, B; Ghannam, M; Ghazaleh, D; Samara, A, 2019)
"Recurrences were noted in 23%."	1.51	Idiopathic intracranial hypertension: Are there predictors for visual outcome or recurrences? ( Celebisoy, N; Gokcay, F; Kisabay, A; Tata, G, 2019)
"Acetazolamide treatment is effective in most cases, and it represents a viable alternative to repeated LP."	1.51	Pseudotumour cerebri in children: Aetiology, clinical features, and progression. ( Aguilera Albesa, S; Azcona Ganuza, G; Gembero Esarte, E; Iridoy Zulet, M; Mosquera Gorostidi, A; Yoldi Petri, ME, 2019)
"Purpose/Aim: Pseudotumor cerebri or idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure of unknown etiology."	1.46	A case series of dural venous sinus stenting in idiopathic intracranial hypertension: association of outcomes with optical coherence tomography. ( Abraham, MG; Arnold, PM; Camarata, PJ; Peterson, JC; Smith, KA; Whittaker, TJ, 2017)
"Acetazolamide is a carbonic anhydrase inhibitor that is used to treat idiopathic intracranial hypertension, glaucoma, and epilepsy."	1.43	Possible association between acetazolamide administration during pregnancy and multiple congenital malformations. ( Al-Jobair, AM; Al-Saleem, AI, 2016)
"Pseudotumor cerebri is an idiopathic increase in intracranial pressure, which commonly affects obese women of fertile age."	1.42	[Intracranial hypertension and jugular vein thrombosis]. ( Helbig, H; Konrad, J; Oberacher-Velten, I; Vogt, R, 2015)
"The patient was diagnosed with idiopathic intracranial hypertension and treated with azetazolamide."	1.39	[Idiopathic intracranial hypertension is a rare cause of headache in children]. ( Hansen, JK; Møller, HU; Viuff, AC, 2013)
"Acetazolamide was the drug of choice, with relatively low dosages used."	1.39	Pseudotumor cerebri in childhood and adolescence -- results of a Germany-wide ESPED-survey. ( Distelmaier, F; Mayatepek, E; Tibussek, D; von Kries, R, 2013)
"Pseudotumor cerebri or idiopathic intracranial hypertension is characterized by normal spinal fluid composition and increased intracranial pressure in the absence of a space-occupying lesion."	1.39	Viral-induced intracranial hypertension mimicking pseudotumor cerebri. ( Kassis, I; Kra-Oz, Z; Ravid, S; Shachor-Meyouhas, Y; Shahar, E, 2013)
"Pseudotumor cerebri is an avoidable cause of visual loss, both in adults and children."	1.39	Clinical spectrum of the pseudotumor cerebri in children: etiological, clinical features, treatment and prognosis. ( Canpolat, M; Doğan, H; Gümüş, H; Karaküçük, S; Kumandaş, S; Per, H; Poyrazoğlu, HG; Yıkılmaz, A, 2013)
"A 14 year-old Caucasian boy with idiopathic intracranial hypertension (IIH) presented with blurred vision in his left eye."	1.39	Intravitreal bevacizumab in the treatment of peripapillary choroidal neovascular membrane secondary to idiopathic intracranial hypertension. ( Kwan, AS; Lee, IJ; Maccheron, LJ, 2013)
"Acetazolamide was used as the first drug and was effective in only 4 patients who had no underlying cause."	1.38	Pseudotumour cerebri in children: etiological, clinical features and treatment modalities. ( Hacifazlioglu Eldes, N; Yilmaz, Y, 2012)
"The patient was diagnosed as having idiopathic intracranial hypertension and treated with oral acetazolamide."	1.37	A case of pediatric idiopathic intracranial hypertension presenting with divergence insufficiency. ( Kang, HM; Kim, HY, 2011)
"Pseudotumor cerebri has only been described after successful surgery for Cushing's disease (CD) in case reports."	1.36	Pseudotumor cerebri after surgical remission of Cushing's disease. ( Keil, M; Kiehna, EN; Lodish, M; Oldfield, EH; Stratakis, C, 2010)
"Along with the progression, bilateral 6th nerve palsy, impairment of visual acuity and bilateral papilledema appeared."	1.36	[Benign but not harmless intracranial hypertension: a case report]. ( Bonnin, N; Chazal, J; Chiambaretta, F; Dalens, H; Deméocq, F; Duclos, C; Kanold, J; Lacombe, P; Merlin, E; Viorel, A, 2010)
"Treatment with acetazolamide reduced the cerebrospinal pressure."	1.35	[Idiopathic intracranial hypertension without headache detected during a routine health check]. ( Niino, M; Sakushima, K; Sasaki, H; Tsuji, S; Yabe, I, 2008)
"For a diagnosis of idiopathic intracranial hypertension (IIH), she was treated with acetazolamide and methylprednisolone, but vision worsened, so she underwent bilateral optic sheath fenestration (ONSF)."	1.35	Progressive optic neuropathy in idiopathic intracranial hypertension after optic nerve sheath fenestration. ( Siatkowski, RM; Wilkes, BN, 2009)
"Although a stenosis of the transverse sinus has been observed in many IIH patients, the role this feature plays in IIH is in dispute."	1.34	Idiopathic intracranial hypertension and transverse sinus stenosis: a modelling study. ( Hamschin, B; Lakin, WD; Penar, PL; Previte, M; Stevens, SA; Thakore, NJ, 2007)
"Facial paralysis is an uncommon sequela of IIH."	1.34	Facial palsy and fallopian canal expansion associated with idiopathic intracranial hypertension. ( Brackmann, DE; Doherty, JK, 2007)
"However, prompt diagnosis of idiopathic intracranial hypertension and initiation of medical therapy lead to improved symptoms and restored vision."	1.33	Idiopathic intracranial hypertension and sickle cell disease: two case reports. ( Discepola, M; Segal, L, 2005)
"Of 1140 cases of idiopathic intracranial hypertension, six patients had juxtapapillary SRNVM."	1.33	Subretinal neovascular membrane in idiopathic intracranial hypertension. ( Boldt, HC; Kardon, RH; Lee, AG; Wall, M; Wendel, L, 2006)
"Although papilledema is described in various anemias, only one case of PTC with idiopathic aplastic anemia has been reported in the English literature."	1.32	Pseudotumor cerebri in idiopathic aplastic anemia. ( Nazir, SA; Siatkowski, RM, 2003)
"Acetazolamide dosage was given while the patients underwent an immunosuppressive regimen."	1.31	Pseudotumor cerebri in two adolescents with acquired aplastic anemia. ( Bhakta, M; Helton, K; Jeng, MR; Rieman, M; Wang, WC, 2002)
"Minocycline and obesity are recognized as precipitating factors in pseudotumor cerebri syndrome."	1.31	[Bilateral papilledema in young women: two case reports of benign intracranial hypertension?]. ( Cochener, B; Colin, J; Kling, F, 2002)
"Cover test revealed an intermittent esotropia at distance, with full ocular motilities."	1.31	Pseudotumor cerebri in a pre-pubescent child--case report. ( Langford, CM, 2002)
"Complications of otitis media are relatively infrequent, especially since the introduction of effective antimicrobial agents and specific surgical techniques."	1.31	[Sigmoid sinus thrombosis as a complication of otitis media]. ( Ayala Curiel , J; Gracia Remiro , R; Herrera Martín , M; Hortelano López , M; Jiménez Moya , AI; Romero Escos , D; Santana Rodríguez , C, 2000)
"After resolution of the optic disc edema, these three patients were maintained on CPAP but discontinued acetazolamide."	1.31	Sleep apnea and intracranial hypertension in men. ( Eggenberger, E; Golnik, K; Kardon, R; Lee, AG; Wall, M; Yedavally, S, 2002)
"In comparison with patients who have idiopathic intracranial hypertension, our small series of 14 patients diagnosed after the age of 44 years were more often men, were less often obese, were less symptomatic, and had identifiable causes of intracranial hypertension in a substantial minority (29%)."	1.31	Clinical features of late-onset pseudotumor cerebri fulfilling the modified dandy criteria. ( Bandyopadhyay, S; Jacobson, DM, 2002)
"Presenting symptoms of idiopathic intracranial hypertension are known to vary with age."	1.31	Asymptomatic idiopathic intracranial hypertension in young children. ( Weig, SG, 2002)
"Pseudotumor cerebri is a clinical syndrome characterized by increased intracranial pressure in the absence of an intracranial tumor."	1.30	Pseudotumor cerebri as a presenting symptom of acute sinusitis in a child. ( Keren, T; Lahat, E, 1998)
"A 6-year-old girl developed symptoms of benign intracranial hypertension following reduction of oral corticosteroid therapy."	1.30	[Benign intracranial hypertension: an unrecognized complication of corticosteroid therapy]. ( Bader-Meunier, B; Dommergues, JP; Lorrot, M; Sébire, G, 1999)
"To report the features of idiopathic intracranial hypertension in prepubertal children, with emphasis on presentation, treatment, and outcome."	1.30	Idiopathic intracranial hypertension in prepubertal pediatric patients: characteristics, treatment, and outcome. ( Borchert, MS; Cinciripini, GS; Donahue, S, 1999)
"Dural sinus thrombosis is a rare and potentially serious complication of suboccipital craniotomy and translabyrinthine craniectomy."	1.30	Dural sinus thrombosis and pseudotumor cerebri: unexpected complications of suboccipital craniotomy and translabyrinthine craniectomy. ( Keiper, GL; Sherman, JD; Tew, JM; Tomsick, TA, 1999)
"Papilledema from benign intracranial hypertension can cause severe loss of visual acuity and visual field, with an optic neuropathy."	1.30	[Intra-orbital decompression of the optic nerve by opening the peri-optic meninges in the treatment of severe optic neuropathies complicating benign intracranial hypertension]. ( Adenis, JP; Arnaud, B; Candon, E; Frerebeau, P; Villain, M, 1999)
"We report the occurrence of idiopathic intracranial hypertension in a patient treated with ofloxacin, a fluoroquinolone antimicrobial agent, for 16 months."	1.29	Idiopathic intracranial hypertension after ofloxacin treatment. ( Aimard, G; Croisile, B; Getenet, JC; Goudable, B; Grochowicki, M; Trillet, M; Vighetto, A, 1993)
"We report two cases of idiopathic intracranial hypertension causing chronic daily headache with migrainous features in the absence of associated papilledema."	1.29	Chronic daily headache with migrainous features due to papilledema-negative idiopathic intracranial hypertension. ( Huff, AL; Hupp, SL; Rothrock, JF, 1996)
"In previous accounts of idiopathic intracranial hypertension in children, concomitant papilledema, visual symptoms and/or palsy of the sixth cranial nerve are described."	1.29	Idiopathic intracranial hypertension in a young child without visual symptoms or signs. ( Bello, L; Winner, P, 1996)
"Pseudotumor cerebri is a central nervous disorder with elevated intracranial pressure that is most common among young obese women."	1.28	[Pseudotumor cerebri, clinical parameters and therapeutic modalities]. ( Blumer, B; Burde, RM; Killer, HE, 1992)
" We deem the initial dosage of 16 mg Millicorten/day to be therapeutically effective and adequate."	1.28	[Pseudotumor cerebri in pregnancy]. ( Benz, J; Zeller, R, 1990)
"No pregnancy was adversely affected, but symptoms of pseudotumor increased in 9 of 11 pregnancies."	1.28	Pseudotumor cerebri and pregnancy. ( Cefalo, RC; Katz, VL; Peterson, R, 1989)
"After pseudotumor cerebri was diagnosed and the appropriate treatment begun, the papilledema disappeared, but the visual field defect persisted."	1.27	Permanent inferior binasal quadrantanopsia in pseudotumor cerebri. ( Nichelli, P; Penne, A, 1983)
"Pseudotumor cerebri is characterized by increased intracranial pressure and papilledema, with an essentially normal neurologic examination."	1.27	Pseudotumor cerebri. ( Bowman, MA, 1987)
"A review of the most recent 23 cases of benign intracranial hypertension (BIH), admitted to the War Memorial Children's Hospital in London, Ontario, provided a compendium of the clinical manifestations of this disorder in children and adolescents."	1.27	Spectrum of benign intracranial hypertension in children and adolescents. ( Amacher, AL; Spence, JD, 1985)
"A series of 28 patients presenting with benign intracranial hypertension is reported."	1.26	Benign intracranial hypertension: clinical features and diagnosis using computed tomography and treatment. ( Uttley, D; Vassilouthis, J, 1979)

Research

Studies (222)

Authors

Clinical Trials (4)

Trial Overview

Trial Outcomes

Mean Change in Perimetric Mean Deviation

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (8.56)	18.7374
1990's	38 (17.12)	18.2507
2000's	46 (20.72)	29.6817
2010's	99 (44.59)	24.3611
2020's	20 (9.01)	2.80

Authors	Studies
Brun, BN	1
Aylward, SC	2
Vuijk, FA	1
de Bruin, C	1
Peeters-Scholte, CMPCD	1
Notting, IC	1
Thaller, M	1
Wakerley, BR	1
Abbott, S	1
Tahrani, AA	1
Mollan, SP	2
Sinclair, AJ	3
Khushzad, F	1
Kumar, R	1
Muminovic, I	1
Moss, HE	3
Mullen, M	1
Scofield-Kaplan, SM	1
Ford, WC	1
Mancini, R	1
Nia, AM	1
Srinivasan, VM	1
Lall, R	1
Kan, P	1
Souza, MNP	1
Costa, BAL	1
Santos, FRDR	1
Fortini, I	1
Price, M	2
Hofman, PL	2
Hsiao, K	2
Jones, HF	2
Tilak, AM	1
Yang, LC	1
Morgan, J	1
Peña-Garcia, J	1
Thompson, M	1
Burleson, S	1
Atkins, A	1
Sheehan, D	1
Cho, DY	1
Woodworth, BA	1
Grayson, JW	1
Martin, J	1
Sanborn, MR	1
Güngör Tunçer, Ö	1
Nalbantoglu, M	1
Sengul, EA	1
Baykan, B	1
Krajnc, N	1
Itariu, B	1
Macher, S	1
Marik, W	1
Harreiter, J	1
Michl, M	1
Novak, K	1
Wöber, C	1
Pemp, B	1
Bsteh, G	1
Bulkowstein, Y	1
Nitzan-Luques, A	1
Schnapp, A	1
Barnoy, N	1
Reif, S	2
Gilboa, T	1
Volovesky, O	1
Goyal, A	1
Zarroli, K	1
Batur Caglayan, HZ	1
Ucar, M	1
Hasanreisoglu, M	1
Nazliel, B	1
Tokgoz, N	1
Costello, F	1
Skolnik, K	1
Sarna, J	1
Varughese, R	1
Ibrahim, A	1
Hussain, N	1
Ybarra, M	1
Santos, TJD	1
Queiroz, ES	1
Rachid, L	1
Franco, RR	1
Cominato, L	1
Moura, FC	1
Velhote, MC	1
Damiani, D	1
Hollar, RA	2
Fischer, WS	2
Feldon, SE	4
Daou, BJ	1
Sweid, A	1
Weinberg, JH	1
Starke, RM	1
Sergott, RC	2
Doermann, AS	1
Hauge, J	1
Zanaty, M	1
Chalouhi, N	1
Gooch, R	1
Herial, N	1
Zarzour, H	1
Jabbour, P	1
Rosenwasser, RH	1
Tjoumakaris, S	1
Raoof, N	1
Hoffmann, J	1
Berkowitz, E	1
Kopelman, Y	1
Kadosh, D	1
Carasso, S	1
Tiosano, B	1
Kesler, A	5
Geva-Zatorsky, N	1
Juhász, J	1
Lindner, T	1
Jansen, O	1
Margraf, NG	1
Rohr, A	1
Kaufman, DI	1
Friedman, DI	5
Wang, JK	3
Kardon, RH	3
Ledolter, J	1
Sibony, PA	2
Kupersmith, MJ	5
Garvin, MK	2
Albrecht, P	1
Blasberg, C	1
Ringelstein, M	1
Müller, AK	1
Finis, D	1
Guthoff, R	1
Kadas, EM	1
Lagreze, W	1
Aktas, O	1
Hartung, HP	1
Paul, F	1
Brandt, AU	1
Methner, A	1
Smith, SV	1
Tovia, E	1
Oren, A	1
Mitelpunkt, A	1
Fattal-Valevski, A	1
Rossor, T	1
Lim, M	1
VanDenEshof, K	1
Gringras, P	1
Way, AL	1
Raggi, A	1
Grazzi, L	1
Bianchi Marzoli, S	1
Ciasca, P	2
Chiapparini, L	2
Erbetta, A	2
Faragò, G	1
Leonardi, M	1
D'Amico, D	2
Carlisle, A	1
Kennedy, JL	1
Chervinskiy, S	1
Jones, SM	1
Pesek, RD	1
Park, H	1
Lim, GY	1
Eom, TH	1
Sheils, CR	1
Blanchard, LM	1
Noda, M	1
Sonoda, Y	1
Takemoto, M	1
Kira, R	1
Mikkilineni, S	1
Trobe, JD	1
Cornblath, WT	2
De Lott, L	1
Madriz Peralta, G	1
Cestari, DM	1
Yeak, J	1
Zahari, M	1
Singh, S	1
Mohamad, NF	1
Umfress, AC	1
Mawn, LA	1
Joos, KM	1
Balbi, GGM	1
Matas, SL	1
Len, CA	1
Fraga, MM	1
Sousa, IO	1
Terreri, MT	1
Banik, R	1
Ozgonul, C	1
Moinuddin, O	1
Munie, M	1
Lee, MS	2
Bhatti, MT	1
Landau, K	2
Van Stavern, GP	1
Mackay, DD	1
Lebas, M	1
DeLott, LB	1
Besirli, CG	1
Samara, A	1
Ghazaleh, D	1
Berry, B	1
Ghannam, M	1
Tata, G	1
Kisabay, A	1
Gokcay, F	2
Celebisoy, N	2
Sundholm, A	1
Träisk, F	1
Hellgren, K	1
Lundvall, M	1
Söderman, M	1
Gustavsson, B	1
Nilsson Remahl, I	1
Mohammad, Y	1
Aljafen, BN	1
Alnafisah, MS	1
Al-Hussain, FA	1
Viuff, AC	1
Hansen, JK	1
Møller, HU	1
Başar, Ö	1
Başar, N	1
Tuna, Y	1
Yüksel, H	1
Çoban, Ş	1
Tibussek, D	2
Distelmaier, F	2
von Kries, R	1
Mayatepek, E	2
Kupferminc, M	1
Brosh, K	1
Strassman, I	1
Ranganathan, S	1
Lee, SH	1
Checkver, A	1
Sklar, E	1
Lam, BL	2
Danton, GH	1
Alperin, N	1
Ravid, S	1
Shachor-Meyouhas, Y	1
Shahar, E	1
Kra-Oz, Z	1
Kassis, I	1
Aragonès, JM	1
Alonso-Valdés, F	1
McDermott, MP	5
Kieburtz, K	1
Kupersmith, M	2
Stoutenburg, A	1
Keltner, JL	3
Schron, E	1
Corbett, JJ	2
Wall, M	13
Curone, M	1
Farago', G	1
Bianchi-Marzoli, S	1
Bussone, G	1
Younes, S	1
Aissi, M	1
Chérif, Y	1
Daoussi, N	1
Boughammoura, A	1
Frih Ayed, M	1
Sfar, MH	1
Jerbi, S	1
Rodà, D	1
Fons-Estupiña, MC	1
Vidal-Santacana, M	1
Mallery, RM	1
Liu, GT	3
Micieli, JA	1
Al-Obthani, M	1
Sundaram, AN	1
Woolley, R	1
McDermott, M	1
Sun, LW	1
Horton, JC	1
Molobe, LT	1
Shifa, J	1
Silava, C	1
Mojela, K	1
Cainelli, F	1
Vento, S	1
Butori, P	1
Jean-Charles, A	1
Elana, G	1
Merle, H	1
Konrad, J	1
Vogt, R	1
Helbig, H	1
Oberacher-Velten, I	1
Supuran, CT	1
Willenborg, KD	1
Nacimiento, W	1
ten Hove, MW	1
Patel, AD	1
Irrcher, I	1
Au, JN	1
Waslo, CS	1
McGwin, G	1
Huisingh, C	1
Tanne, E	2
Cello, KE	2
Johnson, CA	2
Mathew, M	1
Salahuddin, A	1
Mathew, NR	1
Nandhagopal, R	1
Smith, KA	1
Peterson, JC	1
Arnold, PM	1
Camarata, PJ	1
Whittaker, TJ	1
Abraham, MG	1
Beck, RW	1
Zamba, KD	1
Loo, KG	1
Lim, SA	1
Lim, IL	1
Chan, DW	1
Thakore, RV	1
Johnson, MA	1
Krohel, GB	2
Johnson, LN	2
Al-Saleem, AI	1
Al-Jobair, AM	1
Kwon, YJ	1
Allen, JL	1
McCormack, SE	1
Rook, BS	1
Phillips, PH	1
Espino Barros Palau, A	1
Morgan, ML	1
Yalamanchili, S	1
Lee, AG	5
Abdelfatah, MA	1
Bruce, BB	2
Digre, KB	2
Schron, EB	1
Karenfort, M	1
Harmsen, S	1
Klee, D	1
Libien, J	1
Blaner, W	1
Gao, S	1
Liu, Y	1
Corbett, J	1
Garvin, M	1
Kardon, R	2
Mosquera Gorostidi, A	1
Iridoy Zulet, M	1
Azcona Ganuza, G	1
Gembero Esarte, E	1
Yoldi Petri, ME	1
Aguilera Albesa, S	1
Bäuerle, J	1
Egger, K	1
Harloff, A	1
Gharib, A	1
Khokhar, A	1
Caperton, CV	1
Hamadani, ST	1
Thurtell, MJ	2
Moss, EA	1
Auinger, P	1
Scott, NL	1
Stryjewski, TP	1
Rizzo, JF	1
Marton, E	1
Feletti, A	1
Mazzucco, GM	1
Longatti, P	1
Kuzman, MR	1
Jovanovic, N	1
Vukelja, D	1
Medved, V	1
Hotujac, L	1
Sakushima, K	1
Tsuji, S	1
Niino, M	1
Yabe, I	1
Sasaki, H	1
Wolf, A	1
Hutcheson, KA	1
Parentin, F	1
Marchetti, F	1
Faleschini, E	1
Tonini, G	1
Pensiero, S	1
Mowl, AD	1
Grogg, JA	1
Klein, J	1
Wilkes, BN	1
Siatkowski, RM	3
Kiehna, EN	1
Keil, M	1
Lodish, M	1
Stratakis, C	1
Oldfield, EH	1
Lamirel, C	1
Newman, N	1
Biousse, V	1
Mouzaki, M	1
Nichter, C	1
Qureshi, M	1
Rountree, B	1
Furuya, KN	1
Durán, J	1
Jurado, M	1
Jacobelli, S	1
Eymin, G	1
Castiglione, E	1
Valenzuela, R	1
Gutiérrez, MA	1
Battaglia, F	1
Franques, J	1
Somma-Mauvais, H	1
Roche, PH	1
Skau, M	1
Sander, B	1
Milea, D	1
Jensen, R	1
Duclos, C	1
Bonnin, N	1
Merlin, E	1
Viorel, A	1
Lacombe, P	1
Dalens, H	1
Chiambaretta, F	1
Deméocq, F	1
Chazal, J	1
Kanold, J	1
Fraser, C	1
Plant, GT	1
Ball, AK	1
Howman, A	1
Wheatley, K	1
Burdon, MA	1
Matthews, T	1
Jacks, AS	1
Lawden, M	1
Sivaguru, A	1
Furmston, A	1
Howell, S	1
Sharrack, B	1
Davies, MB	1
Clarke, CE	1
Dessardo, NS	1
Dessardo, S	1
Sasso, A	1
Sarunić, AV	1
Dezulović, MS	1
Patiroglu, T	1
Ozcan, A	1
Karakukcu, M	1
Ozdemir, MA	1
Poyrazoglu, G	1
Canpolat, M	2
Unal, E	1
Kaeser, PF	1
Borruat, FX	1
Kang, HM	1
Kim, HY	1
Hacifazlioglu Eldes, N	1
Yilmaz, Y	1
Dolinsky, DH	1
Armstrong, S	1
Martínez-Varea, A	1
Diago-Almela, VJ	1
Abad-Carrascosa, A	1
Perales-Marín, A	1
Skone, K	1
Abbott, J	1
Wacogne, ID	1
Falardeau, J	2
Lobb, BM	1
Golden, S	1
Maxfield, SD	1
Williams, MW	1
Vishwanath, M	1
Göbel, H	1
Göbel, C	1
Heinze, A	1
Per, H	1
Gümüş, H	1
Poyrazoğlu, HG	1
Yıkılmaz, A	1
Karaküçük, S	1
Doğan, H	1
Kumandaş, S	1
Yang, L	1
Hashemi, N	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
A Multicenter, Double-blind, Randomized, Placebo-controlled Study of Weight-Reduction and/or Low Sodium Diet Plus Acetazolamide vs Diet Plus Placebo in Subjects With Idiopathic Intracranial Hypertension With Mild Visual Loss[NCT01003639]	Phase 2/Phase 3	165 participants (Actual)	Interventional	2010-01-31	Completed
Neurocognitive Outcome in Children Who Suffered From Idiopathic Increased Intracranial Hypertension (IIH)[NCT02857335]		15 participants (Actual)	Interventional	2016-01-31	Active, not recruiting
Acetazolamide for Treating NPH in Shunt-candidates Patients: an Open Label Feasibility Trial[NCT03779594]	Phase 2	15 participants (Anticipated)	Interventional	2018-12-31	Recruiting
Novel Compliant Scaffold With Specific Design for the Treatment of Non-thrombotic Stenosis of Internal Jugular Veins in Patients With Chronic Headache Poor Responder to Best Medical Therapy[NCT04352218]	Phase 2	60 participants (Anticipated)	Interventional	2020-09-30	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Treatment Effects on the Primary Outcome Variable, Mean change From Baseline to Month 6 in Perimetric Mean Deviation (PMD) in the Study Eye. Perimetric mean deviation is a measure of global visual field loss (mean deviation from age-corrected normal values), with a range of 2 to -32 dB; larger negative values indicate greater vision loss. (NCT01003639)
Timeframe: base line and 6 months

Mean Change of Papilledema Grade on Fundus Photography

Intervention	dB (Mean)
Acetazolamide	1.43
Sugar Pill	0.71

Mean change at month 6 as compared to baseline. Frisén papilledema grade is an ordinal scale that uses ocular fundus features to rate the severity of papilledema; grade 0 indicates no features of papilledema and grade 5 indicates severe papilledema. (NCT01003639)
Timeframe: Baseline and 6 Months

Visual Acuity (No. of Correct Letters)

Visual Function Questionnaire (VFQ-25)

Intervention	units on a scale (Mean)
	Study eye	Fellow eye
Acetazolamide	-1.31	-1.14
Sugar Pill	-0.61	-0.52

Intervention	correct letters (Mean)
	Study Eye	Fellow Eye
Acetazolamide	56.8	58.3
Sugar Pill	55.6	56.2

Visual Function Questionnaire (VFQ-25) total score, VFQ-25 10-item neuro-ophthalmic supplement total score: 0-100 (higher scores indicate better quality of life) (NCT01003639)
Timeframe: baseline

Article	Year
Pediatric Intracranial Hypertension: A Spotlight on Imaging, the Idiopathic Intracranial Hypertension Treatment Trial, and COVID-19 Associated Cases. Seminars in pediatric neurology, 2021, Volume: 40 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Child; Combined Modality Therapy; C	2021
Update on Idiopathic Intracranial Hypertension Management. Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:5 Suppl 1 Topics: Acetazolamide; Headache; Humans; Intracranial Hypertension; Obesity; Pseudotumor Cerebri; Vision Dis	2022
Should topiramate be initial therapy in the management of idiopathic intracranial hypertension?: A literature review. Medicine, 2023, Oct-20, Volume: 102, Issue:42 Topics: Acetazolamide; Female; Headache; Humans; Intracranial Hypertension; Intracranial Pressure; Pseudotum	2023
Brief report: Metabolic acidosis in newborn infants following maternal use of acetazolamide during pregnancy. Journal of neonatal-perinatal medicine, 2020, Volume: 13, Issue:3 Topics: Acetazolamide; Acidosis; Carbonic Anhydrase Inhibitors; Female; Humans; Infant, Newborn; Infant, New	2020
Diagnosis and treatment of idiopathic intracranial hypertension. Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:4 Topics: Acetazolamide; Analgesics; Headache; Headache Disorders; Humans; Intracranial Hypertension; Migraine	2021
Should Acetazolamide Be the First-Line Treatment for Patients With Idiopathic Intracranial Hypertension? Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2017, Volume: 37, Issue:2 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Decision Making; Humans; Intracranial Pressure; Magnet	2017
The Idiopathic Intracranial Hypertension Treatment Trial: A Review of the Outcomes. Headache, 2017, Volume: 57, Issue:8 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Humans; Multicenter Studies as Topic; Pseudotumor Cere	2017
Pediatric Intracranial Hypertension: a Current Literature Review. Current pain and headache reports, 2018, Feb-13, Volume: 22, Issue:2 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Early Diagnosis; Humans; Pseudotumor Cerebri; Q	2018
An update of idiopathic intracranial hypertension. Current opinion in ophthalmology, 2018, Volume: 29, Issue:6 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Humans; Intracranial Pressure; Papilledema; Pseudotumo	2018
[Idiopathic intracranial hypertension - Swedish consensus guidelines]. Lakartidningen, 2019, May-15, Volume: 116 Topics: Acetazolamide; Bariatric Surgery; Carbonic Anhydrase Inhibitors; Consensus; Critical Pathways; Diagn	2019
Idiopathic intracranial hypertension and pregnancy. Clinical obstetrics and gynecology, 2013, Volume: 56, Issue:2 Topics: Acetazolamide; Diuretics; Female; Humans; Incidence; Pregnancy; Pregnancy Complications, Cardiovascu	2013
[Idiopathic intracranial hypertension and factor V Leiden mutation]. Journal des maladies vasculaires, 2014, Volume: 39, Issue:4 Topics: Acetazolamide; Activated Protein C Resistance; Brain Ischemia; Factor V; Humans; Magnetic Resonance	2014
Headache and the pseudotumor cerebri syndrome. Current pain and headache reports, 2014, Volume: 18, Issue:9 Topics: Acetazolamide; Back Pain; Diagnosis, Differential; Diuretics; Fructose; Furosemide; Headache Disorde	2014
Acetazolamide for the treatment of idiopathic intracranial hypertension. Expert review of neurotherapeutics, 2015, Volume: 15, Issue:8 Topics: Acetazolamide; Animals; Brain; Carbonic Anhydrase Inhibitors; Humans; Pseudotumor Cerebri	2015
[Characteristic neurological features, differential diagnostic criteria and medicinal treatment of idiopathic intracranial hypertension]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2015, Volume: 112, Issue:10 Topics: Acetazolamide; Cerebrospinal Fluid Shunts; Combined Modality Therapy; Diagnosis, Differential; Fruct	2015
Pediatric pseudotumor cerebri. Current opinion in ophthalmology, 2016, Volume: 27, Issue:5 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Pressure; Child; Humans; Magnetic	2016
Update on Idiopathic Intracranial Hypertension. Neurologic clinics, 2017, Volume: 35, Issue:1 Topics: Acetazolamide; Diuretics; Humans; Papilledema; Pseudotumor Cerebri; Randomized Controlled Trials as	2017
[Idiopathic intracranial hypertension]. Der Nervenarzt, 2017, Volume: 88, Issue:2 Topics: Acetazolamide; Blindness; Combined Modality Therapy; Diagnosis, Differential; Diet Therapy; Evidence	2017
Advances in evaluation and management of pediatric idiopathic intracranial hypertension. Current opinion in ophthalmology, 2008, Volume: 19, Issue:5 Topics: Acetazolamide; Cerebrospinal Fluid Shunts; Child, Preschool; Female; Humans; Infant; Intracranial Pr	2008
The syndrome of pseudotumour cerebri and idiopathic intracranial hypertension. Current opinion in neurology, 2011, Volume: 24, Issue:1 Topics: Acetazolamide; Body Mass Index; Carbonic Anhydrase Inhibitors; Constriction, Pathologic; Humans; Int	2011
[Headache from increased cerebrospinal fluid pressure]. Schmerz (Berlin, Germany), 2012, Volume: 26, Issue:3 Topics: Acetazolamide; Algorithms; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Shunts; Combined Modali	2012
Diagnosis and treatment of idiopathic intracranial hypertension (IIH) in children and adolescents. Current neurology and neuroscience reports, 2013, Volume: 13, Issue:3 Topics: Acetazolamide; Adolescent; Cerebrospinal Fluid Shunts; Child; Diuretics; Headache; Humans; Intracran	2013
Pseudotumor cerebri. Current opinion in ophthalmology, 2003, Volume: 14, Issue:6 Topics: Acetazolamide; Adrenal Cortex Hormones; Carbonic Anhydrase Inhibitors; Diagnosis, Differential; Huma	2003
Drugs used in childhood idiopathic or benign intracranial hypertension. Archives of disease in childhood. Education and practice edition, 2008, Volume: 93, Issue:1 Topics: Acetazolamide; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Cer	2008
[Effect of osmotic diuretics, enzyme-inhibiting diuretics and neuroleptics on cerebral perfusion pressure]. Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1983, Volume: 24, Issue:9 Topics: Acetazolamide; Adrenal Cortex Hormones; Animals; Antipsychotic Agents; Brain Edema; Brain Injuries;	1983
Idiopathic intracranial hypertension after L-thyroxine therapy for acquired primary hypothyroidism. Clinical pediatrics, 1995, Volume: 34, Issue:6 Topics: Acetazolamide; Child; Dose-Response Relationship, Drug; Female; Humans; Hypothyroidism; Pseudotumor	1995
Pseudotumor cerebri in Lyme disease: a case report and literature review. Pediatric neurology, 1998, Volume: 18, Issue:5 Topics: Abducens Nerve; Acetazolamide; Borrelia burgdorferi Group; Carbonic Anhydrase Inhibitors; Ceftriaxon	1998

Article	Year
Retinal vessel diameter changes after 6 months of treatment in the Idiopathic Intracranial Hypertension Treatment Trial. The British journal of ophthalmology, 2020, Volume: 104, Issue:10 Topics: Acetazolamide; Adult; Arterioles; Blood Pressure; Carbonic Anhydrase Inhibitors; Diet Therapy; Doubl	2020
Peripapillary Retinal Pigment Epithelium Layer Shape Changes From Acetazolamide Treatment in the Idiopathic Intracranial Hypertension Treatment Trial. Investigative ophthalmology & visual science, 2017, 05-01, Volume: 58, Issue:5 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Pressure; Female; Follow-Up	2017
The Relationship Between Optic Disc Volume, Area, and Frisén Score in Patients With Idiopathic Intracranial Hypertension. American journal of ophthalmology, 2018, Volume: 195 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid; Double-Blind Method; Femal	2018
Magnetic resonance imaging finding of empty sella in obesity related idiopathic intracranial hypertension is associated with enlarged sella turcica. Neuroradiology, 2013, Volume: 55, Issue:8 Topics: Acetazolamide; Adult; Diuretics; Female; Humans; Hypertrophy; Magnetic Resonance Imaging; Male; Obes	2013
The idiopathic intracranial hypertension treatment trial: design considerations and methods. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2014, Volume: 34, Issue:2 Topics: Acetazolamide; Adolescent; Adult; Antihypertensive Agents; Cerebrospinal Fluid Pressure; Double-Blin	2014
Papilledema Outcomes from the Optical Coherence Tomography Substudy of the Idiopathic Intracranial Hypertension Treatment Trial. Ophthalmology, 2015, Volume: 122, Issue:9 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Double-Blind Method; Follow-Up Studies; Humans; Nerve	2015
Safety and Tolerability of Acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2016, Volume: 36, Issue:1 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Combined Modality Therapy; Diet, So	2016
Factors Affecting Visual Field Outcomes in the Idiopathic Intracranial Hypertension Treatment Trial. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2016, Volume: 36, Issue:1 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Combined Modality Therapy; Diet, So	2016
Visual Field Outcomes for the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:3 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Female; Follow-Up Studies; Humans;	2016
Pseudotumor cerebri: What We Have Learned from the Idiopathic Intracranial Hypertension Treatment Trial. Rhode Island medical journal (2013), 2016, May-02, Volume: 99, Issue:5 Topics: Acetazolamide; Adolescent; Adult; Diuretics; Female; Humans; Male; Middle Aged; North America; Obesi	2016
Quality of life at 6 months in the Idiopathic Intracranial Hypertension Treatment Trial. Neurology, 2016, Nov-01, Volume: 87, Issue:18 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Female; Follow-Up Studies; Humans;	2016
Role of vitamin A metabolism in IIH: Results from the idiopathic intracranial hypertension treatment trial. Journal of the neurological sciences, 2017, Jan-15, Volume: 372 Topics: Acetazolamide; Adult; Anticonvulsants; Carotenoids; Chromatography, High Pressure Liquid; Chromatogr	2017
The Effect of Treatment of Idiopathic Intracranial Hypertension on Prevalence of Retinal and Choroidal Folds. American journal of ophthalmology, 2017, Volume: 176 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Choroid; Dose-Response Relationship, Drug; Follow-Up S	2017
The Longitudinal Idiopathic Intracranial Hypertension Trial: Outcomes From Months 6-12. American journal of ophthalmology, 2017, Volume: 176 Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Dose-Response Relationshi	2017
Optic disc haemorrhages at baseline as a risk factor for poor outcome in the Idiopathic Intracranial Hypertension Treatment Trial. The British journal of ophthalmology, 2017, Volume: 101, Issue:9 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Pressure; Combined Modality	2017
Disease activity in idiopathic intracranial hypertension: a 3-month follow-up study. Journal of neurology, 2011, Volume: 258, Issue:2 Topics: Acetazolamide; Adult; Body Mass Index; Diuretics; Female; Follow-Up Studies; Humans; Male; Papillede	2011
A randomised controlled trial of treatment for idiopathic intracranial hypertension. Journal of neurology, 2011, Volume: 258, Issue:5 Topics: Acetazolamide; Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Humans; Male; Middle	2011
Treatment of idiopathic intracranial hypertension: topiramate vs acetazolamide, an open-label study. Acta neurologica Scandinavica, 2007, Volume: 116, Issue:5 Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Body Weight; Carbonic Anhydrase Inhibitors; Cereb	2007
Behavioral disorders in children with idiopathic intracranial hypertension. Journal of child neurology, 2008, Volume: 23, Issue:4 Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Child; Child Behavior Disorders; Follow-Up	2008
The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri) Ophthalmology, 1998, Volume: 105, Issue:12 Topics: Acetazolamide; Adult; Body Mass Index; Body Weight; Female; Humans; Middle Aged; Obesity; Papilledem	1998
Cerebrovascular reactivity in patients under long-term acetazolamide treatment. Acta neurologica Scandinavica, 2002, Volume: 105, Issue:1 Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Blood Flow Velocity; Cerebral Arteries; Cerebrova	2002

Article	Year
Recurrent Intracranial Hypertension in a Toddler with Graves' Disease. Hormone research in paediatrics, 2022, Volume: 95, Issue:1 Topics: Acetazolamide; Child, Preschool; Female; Graves Disease; Humans; Infant; Intracranial Hypertension;	2022
Managing idiopathic intracranial hypertension in pregnancy: practical advice. Practical neurology, 2022, Volume: 22, Issue:4 Topics: Acetazolamide; Female; Humans; Intracranial Hypertension; Obesity; Pregnancy; Pseudotumor Cerebri; W	2022
Predictive Value of International Classification of Diseases Codes for Idiopathic Intracranial Hypertension in a University Health System. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2022, 03-01, Volume: 42, Issue:1 Topics: Acetazolamide; Humans; International Classification of Diseases; Pseudotumor Cerebri; Retrospective	2022
The Effect of Optic Nerve Sheath Fenestration on Intraocular Pressure in Patients With Idiopathic Intracranial Hypertension. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2022, 03-01, Volume: 42, Issue:1 Topics: Acetazolamide; Eye Diseases; Humans; Intraocular Pressure; Optic Nerve; Pseudotumor Cerebri; Retrosp	2022
Dural Venous Sinus Stenting in Idiopathic Intracranial Hypertension: A National Database Study of 541 Patients. World neurosurgery, 2022, Volume: 167 Topics: Acetazolamide; Cranial Sinuses; Dizziness; Female; Headache; Humans; Intracranial Hypertension; Male	2022
The search for a unifying diagnosis involving neurological, endocrine and immune dysfunction: a case report of a novel presentation of DAVID syndrome. BMC pediatrics, 2022, 12-09, Volume: 22, Issue:1 Topics: Acetazolamide; Adrenocorticotropic Hormone; Child; Child, Preschool; Female; Humans; Hydrocortisone;	2022
The search for a unifying diagnosis involving neurological, endocrine and immune dysfunction: a case report of a novel presentation of DAVID syndrome. BMC pediatrics, 2022, 12-09, Volume: 22, Issue:1 Topics: Acetazolamide; Adrenocorticotropic Hormone; Child; Child, Preschool; Female; Humans; Hydrocortisone;	2022
The search for a unifying diagnosis involving neurological, endocrine and immune dysfunction: a case report of a novel presentation of DAVID syndrome. BMC pediatrics, 2022, 12-09, Volume: 22, Issue:1 Topics: Acetazolamide; Adrenocorticotropic Hormone; Child; Child, Preschool; Female; Humans; Hydrocortisone;	2022
The search for a unifying diagnosis involving neurological, endocrine and immune dysfunction: a case report of a novel presentation of DAVID syndrome. BMC pediatrics, 2022, 12-09, Volume: 22, Issue:1 Topics: Acetazolamide; Adrenocorticotropic Hormone; Child; Child, Preschool; Female; Humans; Hydrocortisone;	2022
Optic nerve sheath diameter correlates to intracranial pressure in spontaneous CSF leak patients. International forum of allergy & rhinology, 2023, Volume: 13, Issue:8 Topics: Acetazolamide; Adult; Aged; Female; Humans; Intracranial Hypertension; Intracranial Pressure; Middle	2023
Dural Venous Sinus Stent Placement Reduces Dosage Requirements for Carbonic Anhydrase Inhibitors in Patients with Idiopathic Intracranial Hypertension. Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:8 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Humans; Pseudotumor Cerebri; Retrospective Stud	2023
Metabolic acidosis during the relapse treatment of idiopathic intracranial hypertension. Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2023, Volume: 35, Issue:2 Topics: Acetazolamide; Acidosis; Adult; COVID-19; Female; Humans; Pandemics; Pseudotumor Cerebri	2023
Treatment with GLP-1 receptor agonists is associated with significant weight loss and favorable headache outcomes in idiopathic intracranial hypertension. The journal of headache and pain, 2023, Jul-18, Volume: 24, Issue:1 Topics: Acetazolamide; Adult; Female; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Headache; H	2023
The manifestations of metabolic acidosis during acetazolamide treatment in a cohort of pediatric idiopathic intracranial hypertension. Pediatric nephrology (Berlin, Germany), 2024, Volume: 39, Issue:1 Topics: Acetazolamide; Acidosis; Carbonic Anhydrase Inhibitors; Child; Humans; Pseudotumor Cerebri; Retrospe	2024
Magnetic Resonance Imaging of Idiopathic Intracranial Hypertension: Before and After Treatment. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2019, Volume: 39, Issue:3 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Magnetic Resonance Imaging; Pap	2019
Respiratory Complications Associated With Acetazolamide Use in the Management of Idiopathic Intracranial Hypertension. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2019, Volume: 39, Issue:4 Topics: Acetazolamide; Acidosis; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Middle Aged; Pseudotu	2019
BARIATRIC SURGERY AS A TREATMENT FOR IDIOPATHIC INTRACRANIAL HYPERTENSION IN A MALE ADOLESCENT: CASE REPORT. Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2020, Volume: 38 Topics: Acetazolamide; Adolescent; Aftercare; Bariatric Surgery; Diuretics; Fundus Oculi; Headache; Humans;	2020
Effect of Shunting on Visual Outcomes and Headache in Patients with Idiopathic Intracranial Hypertension. World neurosurgery, 2020, Volume: 142 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Shunts; Cohort Studies; Dip	2020
"More Guts Than Brains?"-The Role of Gut Microbiota in Idiopathic Intracranial Hypertension. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2022, 03-01, Volume: 42, Issue:1 Topics: Acetazolamide; Brain; Female; Gastrointestinal Microbiome; Humans; Obesity; Papilledema; Pseudotumor	2022
Changes in intracranial venous hemodynamics in a patient with idiopathic intracranial hypertension after lumbar puncture precedes therapeutic success. Journal of magnetic resonance imaging : JMRI, 2018, Volume: 47, Issue:1 Topics: Acetazolamide; Adult; Brain; Carbonic Anhydrase Inhibitors; Diagnosis, Differential; Female; Hemodyn	2018
Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension. Journal of neurology, 2017, Volume: 264, Issue:7 Topics: Acetazolamide; Adult; Algorithms; Atrophy; Carbonic Anhydrase Inhibitors; Case-Control Studies; Dise	2017
Treatment Response in Pediatric Patients With Pseudotumor Cerebri Syndrome. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2017, Volume: 37, Issue:4 Topics: Acetazolamide; Adolescent; Brain; Child; Child, Preschool; Diuretics; Drug Therapy, Combination; Fem	2017
Pseudotumor cerebri syndrome in a patient with narcolepsy type 1. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2018, Volume: 22, Issue:1 Topics: Acetazolamide; Adolescent; Female; Humans; Narcolepsy; Pseudotumor Cerebri	2018
The importance of specific rehabilitation for an obese patient with idiopathic intracranial hypertension: a case report. International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, 2018, Volume: 41, Issue:2 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Diet, Reducing; Female; Humans; Obesity; Papill	2018
Successful desensitization in a pediatric patient with acetazolamide allergy. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2018, Volume: 121, Issue:4 Topics: Acetazolamide; Adolescent; Anaphylaxis; Anticonvulsants; Desensitization, Immunologic; Drug Hypersen	2018
Giant arachnoid granulation in a child with benign intracranial hypertension: an unusual case. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018, Volume: 34, Issue:12 Topics: Acetazolamide; Arachnoid; Child; Diuretics; Female; Humans; Pseudotumor Cerebri	2018
[Successful treatment with topiramate in a case of idiopathic intracranial hypertension refractory to acetazolamide]. No to hattatsu = Brain and development, 2017, Volume: 49, Issue:3 Topics: Acetazolamide; Child; Female; Humans; Magnetic Resonance Imaging; Pseudotumor Cerebri; Treatment Out	2017
Visual Field Mean Deviation at Diagnosis of Idiopathic Intracranial Hypertension Predicts Visual Outcome. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2019, Volume: 39, Issue:2 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Diuretics; Drug Therapy, Combinatio	2019
Co-occurrence of acute ophthalmoplegia (without ataxia) and idiopathic intracranial hypertension. European journal of ophthalmology, 2019, Volume: 29, Issue:4 Topics: Abducens Nerve Diseases; Acetazolamide; Acute Disease; Administration, Oral; Adult; Ataxia; Autoanti	2019
Short-term Optic Disc Cupping Reversal in a Patient With Mild Juvenile Open-angle Glaucoma Due to Early Idiopathic Intracranial Hypertension. Journal of glaucoma, 2019, Volume: 28, Issue:4 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Diet, Reducing; Female; Glaucoma, Open-Angle; Humans;	2019
Pseudotumor cerebri in childhood and adolescence: data from a specialized service. Arquivos de neuro-psiquiatria, 2018, Volume: 76, Issue:11 Topics: Acetazolamide; Adolescent; Child; Child, Preschool; Female; Headache; Humans; Male; Papilledema; Pse	2018
The Effect of Acetazolamide and Weight Loss on Intraocular Pressure in Idiopathic Intracranial Hypertension Patients. Journal of glaucoma, 2019, Volume: 28, Issue:4 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Pressure; Femal	2019
Management of Peripapillary Choroidal Neovascular Membrane in Patients With Idiopathic Intracranial Hypertension. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2019, Volume: 39, Issue:4 Topics: Acetazolamide; Adolescent; Adult; Angiogenesis Inhibitors; Carbonic Anhydrase Inhibitors; Choroidal	2019
Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report. Journal of medical case reports, 2019, Apr-19, Volume: 13, Issue:1 Topics: Acetazolamide; Adult; Facial Paralysis; Female; Headache; Humans; Magnetic Resonance Imaging; Obesit	2019
Idiopathic intracranial hypertension: Are there predictors for visual outcome or recurrences? Clinical neurology and neurosurgery, 2019, Volume: 183 Topics: Acetazolamide; Adult; Female; Humans; Hypertension; Intracranial Pressure; Male; Middle Aged; Pseudo	2019
Pseudotumor cerebri induced by topical application of steroid: a case report. The Journal of international medical research, 2019, Volume: 47, Issue:7 Topics: Acetazolamide; Adult; Anti-Inflammatory Agents; Anticonvulsants; Humans; Hydrocortisone; Male; Progn	2019
[Idiopathic intracranial hypertension is a rare cause of headache in children]. Ugeskrift for laeger, 2013, Mar-04, Volume: 175, Issue:10 Topics: Acetazolamide; Child, Preschool; Diuretics; Headache; Humans; Male; Papilledema; Pseudotumor Cerebri	2013
Acetazolamide induced severe hepatotoxicity. Wiener klinische Wochenschrift, 2013, Volume: 125, Issue:7-8 Topics: Acetazolamide; Adult; Chemical and Drug Induced Liver Injury; Diuretics; Female; Humans; Jaundice; P	2013
Pseudotumor cerebri in childhood and adolescence -- results of a Germany-wide ESPED-survey. Klinische Padiatrie, 2013, Volume: 225, Issue:2 Topics: Acetazolamide; Adolescent; Age Factors; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Comorbi	2013
Unilateral papilledema in pseudotumor cerebri. Seminars in ophthalmology, 2013, Volume: 28, Issue:4 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Intracranial Pressure; Obesity;	2013
Viral-induced intracranial hypertension mimicking pseudotumor cerebri. Pediatric neurology, 2013, Volume: 49, Issue:3 Topics: Acetazolamide; Adolescent; Anticonvulsants; Central Nervous System Viral Diseases; Child; Child, Pre	2013
[Benign intracranial hypertension secondary to hypoparathyroidism]. Revista de neurologia, 2014, Jan-16, Volume: 58, Issue:2 Topics: Acetazolamide; Adult; Calcitriol; Calcium Carbonate; Female; Headache; Humans; Hypocalcemia; Hypopar	2014
Intracranial idiopathic hypertension: 1-year follow-up study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35 Suppl 1 Topics: Acetazolamide; Adult; Body Mass Index; Carbonic Anhydrase Inhibitors; Diagnostic Techniques, Ophthal	2014
[Familial idiopathic intracranial hypertension: two paediatric case reports]. Revista de neurologia, 2014, Jul-16, Volume: 59, Issue:2 Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Child; Female; Genetic Predisposition to D	2014
Pseudo-Foster Kennedy syndrome due to idiopathic intracranial hypertension. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2014, Volume: 49, Issue:4 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Optic Nerve Diseases; Overweigh	2014
Idiopathic intracranial hypertension. JAMA, 2014, Sep-10, Volume: 312, Issue:10 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Diet, Sodium-Restricted; Female; Humans; Male; Pseudot	2014
Idiopathic intracranial hypertension--reply. JAMA, 2014, Sep-10, Volume: 312, Issue:10 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Diet, Sodium-Restricted; Female; Humans; Male; Pseudot	2014
Papilledema associated with puberty. Clinical pediatrics, 2015, Volume: 54, Issue:5 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Diagnosis, Differential; Female; Headache; Huma	2015
Primary pseudotumor cerebri syndrome in a young obese African woman. The Israel Medical Association journal : IMAJ, 2014, Volume: 16, Issue:9 Topics: Acetazolamide; Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Antihypertensive Agents; Diuretic	2014
[Pseudotumor cerebri in children with sickle cell disease]. Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:1 Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Anemia, Sickle Cell; Diplopia; Female; Headache;	2015
[Intracranial hypertension and jugular vein thrombosis]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2015, Volume: 112, Issue:12 Topics: Acetazolamide; Adult; Anticoagulants; Carbonic Anhydrase Inhibitors; Coumarins; Diagnosis, Different	2015
Acetazolamide-Induced Nephrolithiasis in Idiopathic Intracranial Hypertension Patients. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2016, Volume: 36, Issue:2 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Case-Control Studies; Female; Follow-Up Studies	2016
Idiopathic intracranial hypertension presenting as postpartum headache. Neurosciences (Riyadh, Saudi Arabia), 2016, Volume: 21, Issue:1 Topics: Acetazolamide; Adult; Cerebral Veins; Diet, Sodium-Restricted; Diuretics; Female; Headache Disorders	2016
A case series of dural venous sinus stenting in idiopathic intracranial hypertension: association of outcomes with optical coherence tomography. The International journal of neuroscience, 2017, Volume: 127, Issue:2 Topics: Acetazolamide; Adult; Anticonvulsants; Endovascular Procedures; Female; Follow-Up Studies; Headache;	2017
The Idiopathic Intracranial Hypertension Treatment Trial: A Long-Time Coming but Worth the Wait. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2016, Volume: 36, Issue:1 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Humans; Pseudotumor Cerebri;	2016
Guiding follow-up of paediatric idiopathic intracranial hypertension with optical coherence tomography. BMJ case reports, 2016, Mar-03, Volume: 2016 Topics: Acetazolamide; Adolescent; Child; Diuretics; Female; Follow-Up Studies; Humans; Papilledema; Pseudot	2016
Possible association between acetazolamide administration during pregnancy and multiple congenital malformations. Drug design, development and therapy, 2016, Volume: 10 Topics: Abnormalities, Multiple; Acetazolamide; Child; Female; Humans; Limb Deformities, Congenital; Male; P	2016
Presumed Pseudotumor Cerebri Syndrome After Withdrawal of Inhaled Glucocorticoids. Pediatrics, 2016, Volume: 137, Issue:6 Topics: Acetazolamide; Administration, Inhalation; Asthma; Child; Diplopia; Female; Glucocorticoids; Growth;	2016
Fulminant idiopathic intracranial hypertension managed with oral acetazolamide. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2016, Volume: 51, Issue:4 Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Pseudotum	2016
Normal Pressure Pseudotumor Cerebri: A Series of Six Patients. Turkish neurosurgery, 2017, Volume: 27, Issue:2 Topics: Acetazolamide; Adult; Cerebrospinal Fluid Pressure; Female; Humans; Intracranial Hypertension; Neuro	2017
Probable pseudotumor cerebri complex in 25 children. Further support of a concept. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2017, Volume: 21, Issue:2 Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Cerebrospinal Fluid Pressure; Child; Child, Pres	2017
Pseudotumour cerebri in children: Aetiology, clinical features, and progression. Neurologia, 2019, Volume: 34, Issue:2 Topics: Acetazolamide; Adolescent; Child; Disease Progression; Female; Humans; Male; Pseudotumor Cerebri; Re	2019
Desensitization to acetazolamide in a patient with previous antimicrobial sulfonamide allergy. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017, Volume: 118, Issue:3 Topics: Acetazolamide; Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Desensitization, Immunologic; D	2017
A Young Woman With Headaches and Blurry Vision. JAMA ophthalmology, 2017, 06-01, Volume: 135, Issue:6 Topics: Acetazolamide; Angiogenesis Inhibitors; Bevacizumab; Carbonic Anhydrase Inhibitors; Choroidal Neovas	2017
Pseudotumor cerebri in pediatric age: role of obesity in the management of neurological impairments. Nutritional neuroscience, 2008, Volume: 11, Issue:1 Topics: Acetazolamide; Adolescent; Cerebrospinal Fluid; Child; Child, Preschool; Cranial Nerve Diseases; Die	2008
Psychiatric symptoms in idiopathic intracranial hypertension. Psychiatry and clinical neurosciences, 2008, Volume: 62, Issue:3 Topics: Acetazolamide; Adult; Borderline Personality Disorder; Depersonalization; Diagnosis, Differential; D	2008
[Idiopathic intracranial hypertension without headache detected during a routine health check]. Rinsho shinkeigaku = Clinical neurology, 2008, Volume: 48, Issue:6 Topics: Acetazolamide; Female; Fundus Oculi; Headache; Humans; Middle Aged; Papilledema; Physical Examinatio	2008
Acute comitant esotropia secondary to idiopathic intracranial hypertension in a child receiving recombinant human growth hormone. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2009, Volume: 44, Issue:1 Topics: Acetazolamide; Acute Disease; Child; Dexamethasone; Diplopia; Drug Therapy, Combination; Esotropia;	2009
Secondary pseudotumour cerebri in a patient undergoing sexual reassignment therapy. Clinical & experimental optometry, 2009, Volume: 92, Issue:5 Topics: Acetazolamide; Androgens; Diuretics; Drug Administration Schedule; Humans; Injections, Intramuscular	2009
Progressive optic neuropathy in idiopathic intracranial hypertension after optic nerve sheath fenestration. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2009, Volume: 29, Issue:4 Topics: Acetazolamide; Adolescent; Decompression, Surgical; Disease Progression; Female; Humans; Methylpredn	2009
Pseudotumor cerebri after surgical remission of Cushing's disease. The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:4 Topics: Acetazolamide; ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Anti-Inflammatory Agents; Carbon	2010
Choroidal infarction in fulminant idiopathic intracranial hypertension. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2010, Volume: 30, Issue:2 Topics: Acetazolamide; Choroid; Choroid Diseases; Diuretics; Female; Headache; Humans; Infarction; Ophthalmi	2010
Idiopathic intracranial hypertension in two patients with Alagille syndrome. Journal of child neurology, 2010, Volume: 25, Issue:8 Topics: Acetazolamide; Age of Onset; Alagille Syndrome; Cerebrospinal Fluid Pressure; Child, Preschool; Diur	2010
[Pseudotumor cerebri secondary to Behçet disease. Report of one case]. Revista medica de Chile, 2010, Volume: 138, Issue:3 Topics: Acetazolamide; Adolescent; Behcet Syndrome; Colchicine; Female; Humans; Pseudotumor Cerebri	2010
[Clinical presentation suggesting Bickerstaff encephalitis and intracranial hypertension]. Revue neurologique, 2011, Volume: 167, Issue:2 Topics: Acetazolamide; Diuretics; Electroencephalography; Electromyography; Encephalitis; Gait Disorders, Ne	2011
[Benign but not harmless intracranial hypertension: a case report]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:12 Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Diplopia; Diuretics; Female; Humans; Meningitis,	2010
Pediatric idiopathic intracranial hypertension: clinical and demographic features. Collegium antropologicum, 2010, Volume: 34 Suppl 2 Topics: Acetazolamide; Adolescent; Child; Diuretics; Female; Humans; Male; Obesity; Ophthalmoscopy; Papilled	2010
Mycophenolate mofetil-induced pseudotumor cerebri in a boy with autoimmune lymphoproliferative disease. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011, Volume: 27, Issue:5 Topics: Acetazolamide; Autoimmune Lymphoproliferative Syndrome; Carbonic Anhydrase Inhibitors; Child, Presch	2011
Peripapillary neovascular membrane: a rare cause of acute vision loss in pediatric idiopathic intracranial hypertension. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2011, Volume: 15, Issue:1 Topics: Acetazolamide; Acute Disease; Administration, Oral; Adolescent; Blindness; Cerebrospinal Fluid Press	2011
A case of pediatric idiopathic intracranial hypertension presenting with divergence insufficiency. Korean journal of ophthalmology : KJO, 2011, Volume: 25, Issue:4 Topics: Acetazolamide; Administration, Oral; Child; Diagnosis, Differential; Diuretics; Esotropia; Exotropia	2011
Pseudotumour cerebri in children: etiological, clinical features and treatment modalities. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:4 Topics: Acetazolamide; Adolescent; Anti-Inflammatory Agents; Anticonvulsants; Cerebrospinal Fluid Pressure;	2012
An 8-year-old girl with headache and syncope. Pediatric annals, 2011, Volume: 40, Issue:12 Topics: Acetazolamide; Child; Diuretics; Female; Headache; Humans; Insulin Resistance; Obesity; Pseudotumor	2011
Progressive visual loss in a pregnant woman with idiopathic intracranial hypertension. European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 163, Issue:1 Topics: Acetazolamide; Adult; Female; Humans; Obesity; Pregnancy; Pregnancy Complications; Pseudotumor Cereb	2012
From menorrhagia to manometers. Archives of disease in childhood. Education and practice edition, 2012, Volume: 97, Issue:3 Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Anemia; Coombs Test; Diuretics; Fatigue; Female;	2012
The use of acetazolamide during pregnancy in intracranial hypertension patients. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2013, Volume: 33, Issue:1 Topics: Acetazolamide; Adult; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnan	2013
Intracranial hypertension: was it really idiopathic? BMJ case reports, 2011, Apr-19, Volume: 2011 Topics: Acetazolamide; Adult; Anticoagulants; Anticonvulsants; Diagnosis, Differential; Drug Therapy, Combin	2011
Clinical spectrum of the pseudotumor cerebri in children: etiological, clinical features, treatment and prognosis. Brain & development, 2013, Volume: 35, Issue:6 Topics: Acetazolamide; Adolescent; Age of Onset; Anticonvulsants; Child; Child, Preschool; Female; Humans; I	2013
Intracranial complications of idiopathic intracranial hypertension. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2012, Volume: 47, Issue:6 Topics: Acetazolamide; Adult; Anticoagulants; Cerebral Veins; Drug Therapy, Combination; Female; Humans; Mag	2012
Intravitreal bevacizumab in the treatment of peripapillary choroidal neovascular membrane secondary to idiopathic intracranial hypertension. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2013, Volume: 33, Issue:2 Topics: Acetazolamide; Adolescent; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab;	2013
Optic nerve sonography to monitor treatment efficacy in idiopathic intracranial hypertension: a case report. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2013, Volume: 23, Issue:4 Topics: Acetazolamide; Antihypertensive Agents; Combined Modality Therapy; Diet Therapy; Female; Humans; Mid	2013
Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease. American journal of ophthalmology, 2002, Volume: 134, Issue:5 Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Choroid; Crohn Disease; F	2002
Pseudotumor cerebri in two adolescents with acquired aplastic anemia. Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:9 Topics: Acetazolamide; Adolescent; Anemia, Aplastic; Anticonvulsants; Brain; Carbonic Anhydrase Inhibitors;	2002
[Bilateral papilledema in young women: two case reports of benign intracranial hypertension?]. Journal francais d'ophtalmologie, 2002, Volume: 25, Issue:8 Topics: Acetazolamide; Adolescent; Adult; Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Female; Fluo	2002
Pseudotumor cerebri in a pre-pubescent child--case report. Optometry (St. Louis, Mo.), 2002, Volume: 73, Issue:11 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Diplopia; Esotropia; Headache; Humans; Intracra	2002
Electrophysiological evidence of trigeminal neuropathy in pseudotumor cerebri. Journal of neurology, 2002, Volume: 249, Issue:11 Topics: Acetazolamide; Adult; Cerebrospinal Fluid Shunts; Female; Humans; Intracranial Hypertension; Neural	2002
Pseudotumor cerebri in idiopathic aplastic anemia. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2003, Volume: 7, Issue:1 Topics: Acetazolamide; Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Humans; Male;	2003
A 14-year-old Nigerian female with idiopathic intracranial hypertension (Pseudotumor cerebri or benign intracranial hypertension). African health sciences, 2002, Volume: 2, Issue:3 Topics: Acetazolamide; Adolescent; Anticonvulsants; Female; Headache Disorders, Secondary; Humans; Nigeria;	2002
PSEUDOTUMOR CEREBRI. REPORT OF SIX CASES COMPARED WITH ONE CASE OF PSEUDOPAPILLEDEMA. The Medical annals of the District of Columbia, 1964, Volume: 33 Topics: Acetazolamide; Brain Diseases; Brain Neoplasms; Chlorothiazide; Diagnosis; Diet, Sodium-Restricted;	1964
The headache of teenage acne. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Jun-08, Volume: 170, Issue:12 Topics: Acetazolamide; Acne Vulgaris; Adolescent; Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Fema	2004
Myxedema, papilledema, and elevated CSF protein. Neurology, 2004, Aug-24, Volume: 63, Issue:4 Topics: Acetazolamide; Anemia, Pernicious; Cerebrospinal Fluid Proteins; Confusion; Diagnosis, Differential;	2004
The use of acetazolamide in idiopathic intracranial hypertension during pregnancy. American journal of ophthalmology, 2005, Volume: 139, Issue:5 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Pregnancy; Pregnancy Complicati	2005
Metamorphopsia as an initial complaint of idiopathic intracranial hypertension. Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:7 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Fluorescein Angiography; Humans; Magnet	2005
Non-operative management of benign intracranial hypertension presenting with complete visual loss and deafness. Pediatric neurosurgery, 2006, Volume: 42, Issue:1 Topics: Acetazolamide; Adolescent; Blindness; Deafness; Diuretics; Female; Humans; Niacin; Pseudotumor Cereb	2006
Idiopathic intracranial hypertension and sickle cell disease: two case reports. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2005, Volume: 40, Issue:6 Topics: Acetazolamide; Adolescent; Adult; Anemia, Sickle Cell; Carbonic Anhydrase Inhibitors; Female; Headac	2005
Subretinal neovascular membrane in idiopathic intracranial hypertension. American journal of ophthalmology, 2006, Volume: 141, Issue:3 Topics: Acetazolamide; Combined Modality Therapy; Diuretics; Female; Furosemide; Humans; Laser Coagulation;	2006
Puberty as a risk factor for less favorable visual outcome in idiopathic intracranial hypertension. American journal of ophthalmology, 2006, Volume: 142, Issue:2 Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Female; Fo	2006
Idiopathic intracranial hypertension and transverse sinus stenosis: a modelling study. Mathematical medicine and biology : a journal of the IMA, 2007, Volume: 24, Issue:1 Topics: Acetazolamide; Algorithms; Cerebrospinal Fluid; Cerebrospinal Fluid Pressure; Cerebrovascular Circul	2007
Pseudotumor cerebri in children with Down syndrome. Ophthalmology, 2007, Volume: 114, Issue:9 Topics: Acetazolamide; Child; Child, Preschool; Diuretics; Down Syndrome; Female; Humans; Intracranial Press	2007
Facial palsy and fallopian canal expansion associated with idiopathic intracranial hypertension. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2007, Volume: 28, Issue:5 Topics: Acetazolamide; Child; Diagnosis, Differential; Facial Paralysis; Geniculate Ganglion; Hearing Loss,	2007
Intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to pseudotumor cerebri. International ophthalmology, 2009, Volume: 29, Issue:3 Topics: Acetazolamide; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Human	2009
Ophthalmodynamometric measurement of central retinal vein pressure as surrogate of intracranial pressure in idiopathic intracranial hypertension. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008, Volume: 246, Issue:7 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Central Venous Pressure; Cerebrospinal Fluid Pr	2008
Asymptomatic idiopathic intracranial hypertension in children. Acta neurologica Scandinavica, 2008, Volume: 118, Issue:4 Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Diuretics; Female; Humans; Male; Ob	2008
Pseudotumor cerebri as a reversible side effect of all-trans retinoic acid treatment in acute promyelocytic leukaemia. European journal of neurology, 2008, Volume: 15, Issue:7 Topics: Acetazolamide; Adult; Anticonvulsants; Antineoplastic Agents; Female; Humans; Idarubicin; Leukemia,	2008
Permanent inferior binasal quadrantanopsia in pseudotumor cerebri. Italian journal of neurological sciences, 1983, Volume: 4, Issue:2 Topics: Acetazolamide; Humans; Male; Middle Aged; Papilledema; Pseudotumor Cerebri; Vision Disorders	1983
Benign intracranial hypertension, monoclonal gammopathy, and superior sagittal sinus thrombosis. Southern medical journal, 1983, Volume: 76, Issue:5 Topics: Acetazolamide; Arm; Cranial Sinuses; Humans; Hypergammaglobulinemia; Immunoglobulin G; Leg; Male; Mi	1983
Pseudotumor cerebri and hypothyroidism. Archives of internal medicine, 1983, Volume: 143, Issue:1 Topics: Acetazolamide; Adult; Body Weight; Drainage; Female; Glucocorticoids; Humans; Hypothyroidism; Intrac	1983
New and old concepts in sarcoidosis. The Western journal of medicine, 1983, Volume: 138, Issue:4 Topics: Acetazolamide; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Prednisone; Prop	1983
[Principles and results of treating the hypertension-hydrocephalic syndrome in children]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:10 Topics: Acetazolamide; Adolescent; Child; Child, Preschool; Electroencephalography; Humans; Hydrocephalus; I	1982
Magnetic resonance visualization of the swollen optic disc in papilledema. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 1995, Volume: 15, Issue:2 Topics: Acetazolamide; Administration, Oral; Child; Diuretics; Fundus Oculi; Gadolinium; Humans; Magnetic Re	1995
Pseudotumor cerebri responsive to acetazolamide. The Annals of pharmacotherapy, 1995, Volume: 29, Issue:3 Topics: Acetazolamide; Adolescent; Dexamethasone; Female; Headache; Humans; Pseudotumor Cerebri; Tetracyclin	1995
[Idiopathic intracranial hypertension and tetracycline]. Harefuah, 1994, Volume: 127, Issue:1-2 Topics: Acetazolamide; Adolescent; Adult; Female; Headache; Humans; Male; Papilledema; Pseudotumor Cerebri;	1994
Childhood pseudotumor cerebri: clinical and intracranial pressure response to acetazolamide and furosemide treatment in a case series. Journal of child neurology, 1994, Volume: 9, Issue:2 Topics: Acetazolamide; Administration, Oral; Adolescent; Child; Child, Preschool; Dose-Response Relationship	1994
High-dose methylprednisolone and acetazolamide for visual loss in pseudotumor cerebri. American journal of ophthalmology, 1994, Jul-15, Volume: 118, Issue:1 Topics: Acetazolamide; Acute Disease; Administration, Oral; Adolescent; Adult; Blindness; Drug Therapy, Comb	1994
Leydig cell tumour of the testicle associated with benign intracranial hypertension. Journal of neurology, 1994, Volume: 241, Issue:3 Topics: Acetazolamide; Adult; Feminization; Gonadal Steroid Hormones; Humans; Leydig Cell Tumor; Male; Pitui	1994
Idiopathic intracranial hypertension and facial diplegia. Neurology, 1994, Volume: 44, Issue:2 Topics: Acetazolamide; Adolescent; Diplopia; Facial Nerve; Facial Paralysis; Female; Headache; Humans; Pseud	1994
A young leukemic patient with headache. Journal of the Tennessee Medical Association, 1993, Volume: 86, Issue:11 Topics: Acetazolamide; Adult; Female; Headache; Humans; Leukemia, Myeloid, Acute; Pseudotumor Cerebri	1993
Idiopathic intracranial hypertension after ofloxacin treatment. Acta neurologica Scandinavica, 1993, Volume: 87, Issue:6 Topics: Acetazolamide; Adult; Femoral Fractures; Humans; Intracranial Pressure; Long-Term Care; Male; Ofloxa	1993
Pseudotumor syndrome associated with cerebral venous sinus occlusion and antiphospholipid antibodies. Stroke, 1993, Volume: 24, Issue:3 Topics: Acetazolamide; Antibodies, Antiphospholipid; Cerebral Angiography; Cerebral Veins; Hearing Loss, Noi	1993
Deteriorating renal function with acetazolamide in a renal transplant patient with pseudotumor cerebri. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1993, Volume: 21, Issue:3 Topics: Acetazolamide; Acute Kidney Injury; Adult; Female; Humans; Kidney Transplantation; Pseudotumor Cereb	1993
Benign intracranial hypertension associated with HIV infection. European neurology, 1993, Volume: 33, Issue:3 Topics: Acetazolamide; Adult; AIDS Dementia Complex; Cerebrospinal Fluid Pressure; Female; HIV Seropositivit	1993
Coexistence of migraine and idiopathic intracranial hypertension without papilledema. Neurology, 1996, Volume: 46, Issue:5 Topics: Acetazolamide; Adolescent; Adult; Dihydroergotamine; Diuretics; Ergotamine; Female; Follow-Up Studie	1996
Chronic daily headache with migrainous features due to papilledema-negative idiopathic intracranial hypertension. Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:6 Topics: Acetazolamide; Adult; Chronic Disease; Female; Headache; Humans; Intracranial Pressure; Middle Aged;	1996
Idiopathic intracranial hypertension in a young child without visual symptoms or signs. Headache, 1996, Volume: 36, Issue:9 Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Headache; Humans; Intracranial Pressure; Male;	1996
Pseudotumor cerebri appearing with unilateral papilledema after trabeculectomy. Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:3 Topics: Acetazolamide; Adult; Antimetabolites; Carbonic Anhydrase Inhibitors; Female; Fluorouracil; Fundus O	1997
Optic nerve sheath fenestration for pseudotumor cerebri. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 1997, Volume: 17, Issue:2 Topics: Acetazolamide; Adolescent; Adult; Diuretics; Female; Follow-Up Studies; Humans; Intracranial Pressur	1997
Pseudotumor cerebri sine papilledema with unilateral sixth nerve palsy. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 1998, Volume: 18, Issue:1 Topics: Abducens Nerve; Acetazolamide; Adolescent; Cranial Nerve Diseases; Diplopia; Female; Headache; Human	1998
[Indications for acetazolamide in neurology]. Der Internist, 1998, Volume: 39, Issue:2 Topics: Acetazolamide; Brain; Epilepsy; Humans; Pseudotumor Cerebri; Vasodilation	1998
Pseudotumor cerebri as a presenting symptom of acute sinusitis in a child. Pediatric neurology, 1998, Volume: 19, Issue:2 Topics: Acetazolamide; Acute Disease; Adolescent; Amoxicillin; Anti-Inflammatory Agents; Drug Therapy, Combi	1998
[Benign intracranial hypertension: an unrecognized complication of corticosteroid therapy]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:1 Topics: Acetazolamide; Administration, Oral; Anti-Inflammatory Agents; Child; Combined Modality Therapy; Diu	1999
Idiopathic intracranial hypertension in prepubertal pediatric patients: characteristics, treatment, and outcome. American journal of ophthalmology, 1999, Volume: 127, Issue:2 Topics: Acetazolamide; Cerebrospinal Fluid Pressure; Child; Child, Preschool; Diplopia; Drug Therapy, Combin	1999
Pediatric tetracycline-induced pseudotumor cerbri. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 1999, Volume: 3, Issue:1 Topics: Acetazolamide; Acne Vulgaris; Adolescent; Anti-Bacterial Agents; Child; Dexamethasone; Diuretics; Dr	1999
Pseudotumor cerebri secondary to intermediate-dose cytarabine HCl. The Annals of pharmacotherapy, 1999, Volume: 33, Issue:5 Topics: Acetazolamide; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Child; Cytarabine;	1999
Dural sinus thrombosis and pseudotumor cerebri: unexpected complications of suboccipital craniotomy and translabyrinthine craniectomy. Journal of neurosurgery, 1999, Volume: 91, Issue:2 Topics: Acetazolamide; Adult; Anti-Inflammatory Agents; Cerebrospinal Fluid Shunts; Cerebrovascular Circulat	1999
[Intra-orbital decompression of the optic nerve by opening the peri-optic meninges in the treatment of severe optic neuropathies complicating benign intracranial hypertension]. Neuro-Chirurgie, 1999, Volume: 45, Issue:2 Topics: Acetazolamide; Adolescent; Adult; Combined Modality Therapy; Decompression, Surgical; Diuretics; Fem	1999
Weight loss, acetazolamide, and pseudotumor cerebri. Ophthalmology, 1999, Volume: 106, Issue:9 Topics: Acetazolamide; Body Weight; Humans; Obesity; Papilledema; Pseudotumor Cerebri; Weight Loss	1999
[Benign intracranial hypertension following minocycline]. Harefuah, 1998, May-15, Volume: 134, Issue:10 Topics: Acetazolamide; Adolescent; Anti-Bacterial Agents; Diuretics; Female; Headache; Humans; Minocycline;	1998
[Distinct papilledema in pseudotumor cerebri in vitamin A hypervitaminosis. A 35-year-old patient with distinct papilledema and double-image perception]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2000, Volume: 97, Issue:7 Topics: Acetazolamide; Adult; Anti-Inflammatory Agents; Anticonvulsants; Diplopia; Humans; Hypervitaminosis	2000
[Sigmoid sinus thrombosis as a complication of otitis media]. Anales espanoles de pediatria, 2000, Volume: 53, Issue:5 Topics: Acetazolamide; Acetone; Anti-Infective Agents; Anticonvulsants; Child, Preschool; Female; Follow-Up	2000
Benign intracranial hypertension: correlation of cerebral blood flow with disease severity. Clinical neurology and neurosurgery, 2001, Volume: 103, Issue:1 Topics: Acetazolamide; Adult; Brain; Cerebrovascular Circulation; Chronic Disease; Diuretics; Female; Humans	2001
Minocycline and Pseudotumor cerebri: The well-known but well-kept secret. Pediatrics, 2001, Volume: 108, Issue:2 Topics: Acetazolamide; Acne Vulgaris; Child; Drug Information Services; Drug Labeling; Humans; Internship an	2001
Pseudotumor cerebri. Archives of neurology, 2001, Volume: 58, Issue:10 Topics: Acetazolamide; Adrenal Cortex Hormones; Diagnosis, Differential; Furosemide; Humans; Pseudotumor Cer	2001
Pseudotumour cerebri occurring in association with the Chiari malformation. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2002, Volume: 9, Issue:1 Topics: Acetazolamide; Arnold-Chiari Malformation; Child; Female; Humans; Magnetic Resonance Imaging; Pseudo	2002
[Treatment of acne with consequences -- pseudotumor cerebri due to hypervitaminosis A]. Praxis, 2002, Jan-09, Volume: 91, Issue:1-2 Topics: Acetazolamide; Acne Vulgaris; Adolescent; Anticonvulsants; Female; Humans; Pseudotumor Cerebri; Spin	2002
Sleep apnea and intracranial hypertension in men. Ophthalmology, 2002, Volume: 109, Issue:3 Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Humans; Intracranial Pressure; Male; Middle Age	2002
Clinical features of late-onset pseudotumor cerebri fulfilling the modified dandy criteria. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2002, Volume: 22, Issue:1 Topics: Acetazolamide; Adult; Age of Onset; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Diuretic	2002
An 18-year-old woman with unexplained vision loss. Journal of emergency nursing, 2002, Volume: 28, Issue:2 Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Female; Humans; Pseudotumor Cerebri	2002
Asymptomatic idiopathic intracranial hypertension in young children. Journal of child neurology, 2002, Volume: 17, Issue:3 Topics: Acetazolamide; Brain; Carbonic Anhydrase Inhibitors; Child, Preschool; Headache; Humans; Male; Papil	2002
A child with venous sinus thrombosis with initial examination findings of pseudotumor syndrome. Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:6 Topics: Acetazolamide; Brain; Ceftriaxone; Child; Drug Therapy, Combination; Female; Heparin, Low-Molecular-	2002
Benign intracranial hypertension: clinical features and diagnosis using computed tomography and treatment. Surgical neurology, 1979, Volume: 12, Issue:5 Topics: Acetazolamide; Adolescent; Adult; Child; Dexamethasone; Female; Humans; Male; Middle Aged; Pseudotum	1979
Asymptomatic unilateral papilledema in pseudotumor cerebri. Journal of clinical neuro-ophthalmology, 1992, Volume: 12, Issue:4 Topics: Acetazolamide; Adult; Female; Fluorescein Angiography; Fundus Oculi; Humans; Papilledema; Pseudotumo	1992
Visual loss in pseudotumor cerebri from branch retinal artery occlusion. American journal of ophthalmology, 1992, Mar-15, Volume: 113, Issue:3 Topics: Acetazolamide; Adolescent; Blindness; Female; Fundus Oculi; Glucocorticoids; Humans; Papilledema; Ps	1992
[Pseudotumor cerebri, clinical parameters and therapeutic modalities]. Klinische Monatsblatter fur Augenheilkunde, 1992, Volume: 200, Issue:5 Topics: Acetazolamide; Adult; Cerebrospinal Fluid Shunts; Child; Female; Humans; Male; Nerve Compression Syn	1992
[Pseudotumor cerebri in pregnancy]. Gynakologische Rundschau, 1990, Volume: 30, Issue:3 Topics: Acetazolamide; Adult; Brain Neoplasms; Diagnosis, Differential; Female; Fetal Death; Humans; Pregnan	1990
[The effect of acetazolamide-induced, endogenous volume stress of the cerebrospinal system on intracranial pressure. Diamox--effect on intracranial pressure]. Neurochirurgia, 1990, Volume: 33, Issue:2 Topics: Acetazolamide; Adolescent; Adult; Blood-Brain Barrier; Cerebrospinal Fluid Shunts; Female; Humans; I	1990
Unilateral papilledema in pseudotumor cerebri. Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:5 Topics: Acetazolamide; Female; Fluorescein Angiography; Fundus Oculi; Humans; Middle Aged; Papilledema; Pseu	1990
Pseudotumour cerebri with focal neurological deficit. Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:4 Topics: Acetazolamide; Adult; Facial Paralysis; Female; Hemiplegia; Humans; Prednisone; Pseudotumor Cerebri	1990
Malignant pseudotumor cerebri. Report of two cases. Journal of neurosurgery, 1989, Volume: 71, Issue:3 Topics: Acetazolamide; Adolescent; Adult; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Shunts; Dexameth	1989
Pseudotumor cerebri and pregnancy. American journal of perinatology, 1989, Volume: 6, Issue:4 Topics: Acetaminophen; Acetazolamide; Codeine; Female; Furosemide; Humans; Infant, Newborn; Male; Pregnancy;	1989
Pseudotumor cerebri in men. Archives of neurology, 1988, Volume: 45, Issue:8 Topics: Acetazolamide; Adolescent; Adult; Body Weight; Female; Humans; Hypertension; Male; Middle Aged; Obes	1988
Complete external ophthalmoplegia in a case of pseudotumor cerebri. Headache, 1987, Volume: 27, Issue:10 Topics: Acetazolamide; Adult; Dexamethasone; Female; Humans; Ophthalmoplegia; Pseudotumor Cerebri	1987
Persistent disturbances of cognitive functions in patients with pseudotumor cerebri. Acta neurologica Scandinavica, 1986, Volume: 73, Issue:3 Topics: Acetazolamide; Adolescent; Adult; Cognition Disorders; Female; Follow-Up Studies; Humans; Learning;	1986
Pseudotumor cerebri. American family physician, 1987, Volume: 35, Issue:1 Topics: Acetazolamide; Adult; Atenolol; Cerebrospinal Fluid Shunts; Female; Humans; Intracranial Pressure; P	1987
Spectrum of benign intracranial hypertension in children and adolescents. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1985, Volume: 1, Issue:2 Topics: Acetazolamide; Adolescent; Anti-Bacterial Agents; Brain Concussion; Cerebrospinal Fluid Shunts; Chil	1985
Pseudotumor cerebri and Lyme disease: a new association. The Journal of pediatrics, 1985, Volume: 107, Issue:6 Topics: Acetazolamide; Child; Female; Humans; Lyme Disease; Penicillins; Prednisone; Pseudotumor Cerebri	1985
Follow-up study of 100 cases of pseudotumor cerebri. Acta neurochirurgica, 1968, Volume: 18, Issue:4 Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Brain Diseases; Child; Child, P	1968
Letter: Benign intracranial hypertension associated with nitrofurantoin therapy. British medical journal, 1974, Dec-28, Volume: 4, Issue:5947 Topics: Acetazolamide; Cephalometry; Humans; Infant; Male; Nitrofurantoin; Pseudotumor Cerebri	1974
Pseudo-tumor cerebri: further studies. Journal of the National Medical Association, 1973, Volume: 65, Issue:3 Topics: Acetazolamide; Adolescent; Adult; Age Factors; Female; Humans; Middle Aged; Pseudotumor Cerebri	1973

acetazolamide and Pseudotumor Cerebri