acetazolamide has been researched along with Peripheral Nerve Injuries in 1 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Peripheral Nerve Injuries: Injuries to the PERIPHERAL NERVES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Finally, we demonstrate that systemic administration of acetazolamide to rats with PNI produces an antiallodynic effect by itself and an enhancement of the peak analgesic effect with a change in the shape of the dose-response curve of the α1-sparing benzodiazepine L-838,417." | 1.40 | Inhibition of carbonic anhydrase augments GABAA receptor-mediated analgesia via a spinal mechanism of action. ( Asiedu, MN; Hübner, CA; Kaila, K; Mejia, GL; Price, TJ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asiedu, MN | 1 |
| Mejia, GL | 1 |
| Hübner, CA | 1 |
| Kaila, K | 1 |
| Price, TJ | 1 |
1 other study available for acetazolamide and Peripheral Nerve Injuries
| Article | Year |
|---|---|
Inhibition of carbonic anhydrase augments GABAA receptor-mediated analgesia via a spinal mechanism of action.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; | 2014 |