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acetazolamide and Paralysis, Hyperkalemic Periodic

acetazolamide has been researched along with Paralysis, Hyperkalemic Periodic in 11 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Paralysis, Hyperkalemic Periodic: An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)

Research Excerpts

ExcerptRelevanceReference
" In one study dichlorphenamide (DCP) vs placebo was tested in two groups of participants: 42 with hypokalemic periodic paralysis (HypoPP) and 31 with hyperkalemic periodic paralysis (HyperPP), based on clinical criteria."4.84Treatment for periodic paralysis. ( Links, TP; Meola, G; Panzeri, M; Rose, MR; Sansone, V, 2008)
"The acetazolamide (AZA) test is a well-accepted method for measuring the vascular reactivity of the cerebral arteries."2.70Cerebrovascular reactivity in patients under long-term acetazolamide treatment. ( Gadot, N; Kesler, A; Lampl, Y; Lorberboyn, M; Sadeh, M, 2002)
"We report a 65 year-old man with hyperkalemic periodic paralysis and late-onset permanent weakness in association with the common T704M mutation in α-subunit, skeletal muscle voltage-gated sodium channel gene."1.39Long-term effectiveness of acetazolamide on permanent weakness in hyperkalemic periodic paralysis. ( Dejthevaporn, C; Jaovisidha, S; Papsing, C; Phakdeekitcharoen, B; Phudhichareonrat, S; Pulkes, T; Witoonpanich, R, 2013)
"However, the incidence of cardiac dysrhythmia was increased after the use of acetazolamide."1.31[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia controlled with imipramine and acetazolamide]. ( Endo, T; Fujimori, J; Itoyama, Y; Onodera, H; Shiga, Y; Takahashi, T; Takeda, A; Tateyama, M; Yoshimoto, T, 2001)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Statland, JM1
Fontaine, B2
Hanna, MG1
Johnson, NE1
Kissel, JT1
Sansone, VA1
Shieh, PB1
Tawil, RN1
Trivedi, J1
Cannon, SC1
Griggs, RC1
Dejthevaporn, C1
Papsing, C1
Phakdeekitcharoen, B1
Jaovisidha, S1
Phudhichareonrat, S1
Witoonpanich, R1
Pulkes, T1
ALLSOP, JL1
GOULSTON, K1
JOHNSTON, C1
KELLY, D1
RAIL, L1
CARSON, MJ1
PEARSON, CM1
TURPIN, R1
CAILLE, B1
LAFOURCADE, J1
BEBE, M1
NAYRAC, P1
WAROT, P1
FOSSATI, P1
MILBLED, G1
MALAFOSSE, M1
MEIGNIE, S1
SAMAHA, FJ1
Sansone, V1
Meola, G1
Links, TP1
Panzeri, M1
Rose, MR1
Endo, T1
Takeda, A1
Shiga, Y1
Fujimori, J1
Takahashi, T1
Tateyama, M1
Onodera, H1
Itoyama, Y1
Yoshimoto, T1
Kishi, M1
Kurihara, T1
Lampl, Y1
Kesler, A1
Lorberboyn, M1
Gadot, N1
Sadeh, M1

Reviews

4 reviews available for acetazolamide and Paralysis, Hyperkalemic Periodic

ArticleYear
Review of the Diagnosis and Treatment of Periodic Paralysis.
    Muscle & nerve, 2018, Volume: 57, Issue:4

    Topics: Acetazolamide; Andersen Syndrome; Anti-Arrhythmia Agents; Behavior Therapy; Carbonic Anhydrase Inhib

2018
Treatment for periodic paralysis.
    The Cochrane database of systematic reviews, 2008, Jan-23, Issue:1

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans; Hypokalemic Periodic Paralys

2008
[Ion-channel related muscular diseases].
    La Revue de medecine interne, 1999, Volume: 20, Issue:9

    Topics: Acetazolamide; Anti-Arrhythmia Agents; Anticonvulsants; Carbamazepine; Humans; Hypokalemic Periodic

1999
[Periodic paralysis with cardiac arrhythmia(Andersen's syndrome)].
    Ryoikibetsu shokogun shirizu, 2001, Issue:35

    Topics: Acetazolamide; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbonic Anhydrase Inhibitors; Diagno

2001

Trials

1 trial available for acetazolamide and Paralysis, Hyperkalemic Periodic

ArticleYear
Cerebrovascular reactivity in patients under long-term acetazolamide treatment.
    Acta neurologica Scandinavica, 2002, Volume: 105, Issue:1

    Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Blood Flow Velocity; Cerebral Arteries; Cerebrova

2002

Other Studies

6 other studies available for acetazolamide and Paralysis, Hyperkalemic Periodic

ArticleYear
Long-term effectiveness of acetazolamide on permanent weakness in hyperkalemic periodic paralysis.
    Neuromuscular disorders : NMD, 2013, Volume: 23, Issue:5

    Topics: Acetazolamide; Aged; Humans; Male; Muscle Weakness; Mutation; Paralysis, Hyperkalemic Periodic; Time

2013
FAMILIAL HYPERKALAEMIC PERIODIC PARALYSIS.
    Australasian annals of medicine, 1964, Volume: 13

    Topics: Acetazolamide; Adolescent; Blood Chemical Analysis; Calcium; Electrocardiography; Electromyography;

1964
FAMILIAL HYPERKALEMIC PERIODIC PARALYSIS WITH MYOTONIC FEATURES.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: 17-Ketosteroids; Acetazolamide; Adolescent; Biopsy; Blood Chemical Analysis; Child; Dextroamphetamin

1964
[A FAMILIAL DISEASE PRESENTING IN CERTAIN SUBJECTS THE APPEARANCE OF EULENBURG'S PARAMYOTONIA AND RESEMBLING IN OTHERS HEREDITARY EPISODIC ADYNAMIA].
    La Presse medicale, 1964, Dec-12, Volume: 72

    Topics: Acetazolamide; Adolescent; Blood; Child; Drug Therapy; Electromyography; Genetics, Medical; Humans;

1964
HYPERKALEMIC PERIODIC PARALYSIS. A GENETIC STUDY, CLINICAL OBSERVATIONS, AND REPORT OF A NEW METHOD OF THERAPY.
    Archives of neurology, 1965, Volume: 12

    Topics: Acetazolamide; Amphetamine; Amphetamines; Chlorothiazide; Electromyography; Genetics, Medical; Human

1965
[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia controlled with imipramine and acetazolamide].
    No to shinkei = Brain and nerve, 2001, Volume: 53, Issue:4

    Topics: Acetazolamide; Adolescent; Adrenergic Uptake Inhibitors; Anticonvulsants; Arrhythmias, Cardiac; Drug

2001