acetazolamide has been researched along with Osteosarcoma in 2 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide is a simple and effective method of achieving urinary alkalinisation with advantages over oral and intravenous bicarbonate." | 1.28 | Acetazolamide for alkalinisation of urine in patients receiving high-dose methotrexate. ( Earl, H; Shamash, J; Souhami, R, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ZANDER-PRINCIPATI, GE | 1 |
| KUZMA, JF | 1 |
| Shamash, J | 1 |
| Earl, H | 1 |
| Souhami, R | 1 |
2 other studies available for acetazolamide and Osteosarcoma
| Article | Year |
|---|---|
REDUCTION OF STRONTIUM-90 BONE CANCER BY ZIRCONIUM CITRATE.
Topics: Acetazolamide; Animals; Bone Neoplasms; Chelating Agents; Citrates; Citric Acid; Metabolism; Mice; N | 1964 |
Acetazolamide for alkalinisation of urine in patients receiving high-dose methotrexate.
Topics: Acetazolamide; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Kidney; Methotrexate; Ost | 1991 |