acetazolamide has been researched along with Osteomalacia in 2 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Osteomalacia: Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe osteomalacia was present in two epileptic patients who were under long-term treatment with congeners of phenytoin, phenobarbital, and acetazolamide." | 7.65 | Acetazolamide-accelerated anticonvulsant osteomalacia. ( Mallette, LE, 1977) |
| "Severe osteomalacia was present in two epileptic patients who were under long-term treatment with congeners of phenytoin, phenobarbital, and acetazolamide." | 3.65 | Acetazolamide-accelerated anticonvulsant osteomalacia. ( Mallette, LE, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mallette, LE | 2 |
2 other studies available for acetazolamide and Osteomalacia
| Article | Year |
|---|---|
Acetazolamide-accelerated anticonvulsant osteomalacia.
Topics: Acetazolamide; Adult; Anticonvulsants; Calcium; Epilepsy; Female; Humans; Mephobarbital; Osteomalaci | 1977 |
Letter: Anticonvulsants, acetazolamide and osteomalacia.
Topics: Acetazolamide; Drug Synergism; Female; Humans; Osteomalacia; Phenytoin | 1975 |