Page last updated: 2024-10-22

acetazolamide and Obesity

acetazolamide has been researched along with Obesity in 45 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Patients underwent weight loss and treatment with acetazolamide during a 24-week period."9.08The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri) ( Johnson, LN; Krohel, GB; Madsen, RW; March, GA, 1998)
"Obesity is an important risk factor for the development of chronic kidney disease."6.80Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. ( Bar Sheshet Itach, S; Chagnac, A; Erman, A; Gafter, U; Herman-Edelstein, M; Ori, Y; Rozen-Zvi, B; Zingerman, B, 2015)
" The Idiopathic Intracranial Hypertension Treatment Trial, a large, randomized, collaborative clinical trial, evaluated the efficacy of acetazolamide with weight loss versus placebo with weight loss in participants."5.22Pseudotumor cerebri: What We Have Learned from the Idiopathic Intracranial Hypertension Treatment Trial. ( Johnson, LN; Johnson, MA; Krohel, GB; Thakore, RV, 2016)
"Patients underwent weight loss and treatment with acetazolamide during a 24-week period."5.08The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri) ( Johnson, LN; Krohel, GB; Madsen, RW; March, GA, 1998)
" Although more controlled studies would be helpful, relatively clear-cut indications for the use of ventilatory stimulants exist for hypercapnic obesity-hypoventilation patients (medroxyprogesterone), myxedema (thyroid replacement), central apnea (acetazolamide), and periodic breathing in congestive heart failure (theophylline)."4.80Pharmacologic treatment of sleep-disordered breathing. ( Hudgel, DW; Thanakitcharu, S, 1998)
" Following lumbar puncture with opening pressure of 350 mmHg, a diagnosis of pseudotumor cerebri was made and treatment with acetazolamide was started."3.79Unilateral papilledema in pseudotumor cerebri. ( Brosh, K; Strassman, I, 2013)
"Obesity is an important risk factor for the development of chronic kidney disease."2.80Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. ( Bar Sheshet Itach, S; Chagnac, A; Erman, A; Gafter, U; Herman-Edelstein, M; Ori, Y; Rozen-Zvi, B; Zingerman, B, 2015)
"In cancer patients with hypersplenism-related thrombocytopenia, PSAE is a safe intervention that effects a durable elevation in platelet counts across a range of malignancies and following the re-initiation of chemotherapy."2.73 ( Aasbrenn, M; Abd El-Aty, AM; Abdu, A; Abraha, HB; Achour, A; Acquaroni, M; Addeo, P; Agback, P; Agback, T; Al-Alwan, M; Al-Mazrou, A; Al-Mohanna, F; Aliste, M; Almquist, J; Andel, J; Ando, M; Angelov, A; Annuar, MSM; Antwi, K; Arroliga, AC; Arruda, SLM; Asch, SM; Averous, G; Ayaz, S; Ayer, GB; Bachellier, P; Ball, S; Banijamali, AR; Barden, TC; Bartoncini, S; Bedanie, G; Bellò, M; Benić, F; Berhe, GG; Bertiger, G; Beumer, JH; Bhandari, B; Bond, DS; Boules, M; Braüner Christensen, J; Brown-Johnson, C; Burgstaller, S; Cao, L; Capasso, C; Carlevato, R; Carvalho, AE; Ceci, F; Chagas, ATA; Chavan, SG; Chen, AP; Chen, HC; Chen, J; Chen, Q; Chen, Y; Chen, YF; Christ, ER; Chu, CW; Covey, JM; Coyne, GO'; Cristea, MC; Currie, MG; Dahdal, DN; Dai, L; Dang, Z; de Abreu, NL; de Carvalho, KMB; de la Plaza Llamas, R; Deandreis, D; Del Prete, S; Dennis, JA; Deur, J; Díaz Candelas, DA; Divyapriya, G; Djanani, A; Dodig, D; Doki, Y; Doroshow, JH; Dos Santos, RC; Durairaj, N; Dutra, ES; Eguchi, H; Eisterer, W; Ekmann, A; Elakkad, A; Evans, WE; Fan, W; Fang, Z; Faria, HP; Farris, SG; Fenoll, J; Fernandez-Botran, R; Flores, P; Fujita, J; Gan, L; Gandara, DR; Gao, X; Garcia, AA; Garrido, I; Gebru, HA; Gerger, A; Germano, P; Ghamande, S; Ghebeh, H; Giver Jensen, T; Go, A; Goichot, B; Goldwater, M; Gontero, P; Greil, R; Gruenberger, B; Guarneri, A; Guo, Y; Gupta, S; Haxholdt Lunn, T; Hayek, AJ; He, ML; Hellín, P; Hepprich, M; Hernández de Rodas, E; Hill, A; Hndeya, AG; Holdsworth, LM; Hookey, L; Howie, W; Hu, G; Huang, JD; Huang, SY; Hubmann, E; Hwang, SY; Imamura, H; Imperiale, A; Jiang, JQ; Jimenez, JL; Jin, F; Jin, H; Johnson, KL; Joseph, A; Juwara, L; Kalapothakis, E; Karami, H; Karayağiz Muslu, G; Kawabata, R; Kerwin, J; Khan, I; Khin, S; Kidanemariam, HG; Kinders, RJ; Klepov, VV; Koehler, S; Korger, M; Kovačić, S; Koyappayil, A; Kroll, MH; Kuban, J; Kummar, S; Kung, HF; Kurokawa, Y; Laengle, F; Lan, J; Leal, HG; Lee, MH; Lemos, KGE; Li, B; Li, G; Li, H; Li, X; Li, Y; Li, Z; Liebl, W; Lillaz, B; Lin, F; Lin, L; Lin, MCM; Lin, Y; Lin, YP; Lipton, RB; Liu, J; Liu, W; Liu, Z; Lu, J; Lu, LY; Lu, YJ; Ludwig, S; Luo, Y; Ma, L; Ma, W; Machado-Coelho, GLL; Mahmoodi, B; Mahoney, M; Mahvash, A; Mansour, FA; Mao, X; Marinho, CC; Masferrer, JL; Matana Kaštelan, Z; Melendez-Araújo, MS; Méndez-Chacón, E; Miletić, D; Miller, B; Miller, E; Miller, SB; Mo, L; Moazzen, M; Mohammadniaei, M; Montaz-Rosset, MS; Mousavi Khaneghah, A; Mühlethaler, K; Mukhopadhyay, S; Mulugeta, A; Nambi, IM; Navarro, S; Nazmara, S; Neumann, HJ; Newman, EM; Nguyen, HTT; Nicolato, AJPG; Nicolotti, DG; Nieva, JJ; Nilvebrant, J; Nocentini, A; Nugent, K; Nunez-Rodriguez, DL; Nygren, PÅ; Oberli, A; Oderda, M; Odisio, B; Oehler, L; Otludil, B; Overman, M; Özdemir, M; Pace, KA; Palm, H; Parchment, RE; Parise, R; Passera, R; Pavlovic, J; Pecherstorfer, M; Peng, Z; Pérez Coll, C; Petzer, A; Philipp-Abbrederis, K; Pichler, P; Piekarz, RL; Pilati, E; Pimentel, JDSM; Posch, F; Prager, G; Pressel, E; Profy, AT; Qi, P; Qi, Y; Qiu, C; Rajasekhar, B; Ramia, JM; Raynor, HA; Reis, VW; Reubi, JC; Ricardi, U; Riedl, JM; Romano, F; Rong, X; Rubinstein, L; Rumboldt, Z; Sabir, S; Safaeinili, N; Sala, BM; Sandoval Castillo, L; Sau, M; Sbhatu, DB; Schulte, T; Scott, V; Shan, H; Shao, Y; Shariatifar, N; Shaw, JG; She, Y; Shen, B; Shernyukov, A; Sheth, RA; Shi, B; Shi, R; Shum, KT; Silva, JC; Singh, A; Sinha, N; Sirajudeen, AAO; Slaven, J; Sliwa, T; Somme, F; Song, S; Steinberg, SM; Subramaniam, R; Suetta, C; Sui, Y; Sun, B; Sun, C; Sun, H; Sun, Y; Supuran, CT; Surger, M; Svartz, G; Takahashi, T; Takeno, A; Tam, AL; Tang, Z; Tanner, JA; Tannich, E; Taye, MG; Tekle, HT; Thomas, GJ; Tian, Y; Tobin, JV; Todd Milne, G; Tong, X; Une, C; Vela, N; Venkateshwaran, U; Villagrán de Tercero, CI; Wakefield, JD; Wampfler, R; Wan, M; Wang, C; Wang, J; Wang, L; Wang, S; Waser, B; Watt, RM; Wei, B; Wei, L; Weldemichael, MY; Wellmann, IA; Wen, A; Wild, D; Wilthoner, K; Winder, T; Wing, RR; Winget, M; Wöll, E; Wong, KL; Wong, KT; Wu, D; Wu, Q; Wu, Y; Xiang, T; Xiang, Z; Xu, F; Xu, L; Yamasaki, M; Yamashita, K; Yan, H; Yan, Y; Yang, C; Yang, H; Yang, J; Yang, N; Yang, Y; Yau, P; Yu, M; Yuan, Q; Zhan, S; Zhang, B; Zhang, H; Zhang, J; Zhang, N; Zhang, Y; Zhao, X; Zheng, BJ; Zheng, H; Zheng, W; Zhou, H; Zhou, X; Zhu, S; Zimmer, DP; Zionts, D; Zitella, A; Zlott, J; Zolfaghari, K; Zuo, D; Zur Loye, HC; Žuža, I, 2007)
"Symptomatic treatment of headache is recommended."2.61[Idiopathic intracranial hypertension - Swedish consensus guidelines]. ( Gustavsson, B; Hellgren, K; Lundvall, M; Nilsson Remahl, I; Söderman, M; Sundholm, A; Träisk, F, 2019)
"Obesity is an important risk factor for primary and secondary PTC in post-pubertal children."2.53Pediatric pseudotumor cerebri. ( Phillips, PH; Rook, BS, 2016)
"Some theories - such as the dural sinus stenosis theory - seem to ignore the relationship with weight gain; others have proposed a direct link between obesity and raised intracranial pressure through a specific fat distribution in the body; others through the production of lipokines; and yet others have suggested a converse causation with raised intracranial pressure giving rise to obesity."2.47The syndrome of pseudotumour cerebri and idiopathic intracranial hypertension. ( Fraser, C; Plant, GT, 2011)
"Although weight gain is expected in pregnancy, excessive weight gain may exacerbate IIH and increase maternal and fetal complications; evidence-based recommendations for non-IIH pregnancies may help in guiding optimal gestational weight gain."1.72Managing idiopathic intracranial hypertension in pregnancy: practical advice. ( Abbott, S; Mollan, SP; Sinclair, AJ; Tahrani, AA; Thaller, M; Wakerley, BR, 2022)
"Acetazolamide prophylaxis was associated with decreased risk of AMS."1.72Risk factors for acute mountain sickness in travellers to Cusco, Peru: coca leaves, obesity and sex. ( Cabada, MM; Caravedo, MA; Morales, ML; Mozo, K; Smiley, H; Stuart, J; Tilley, DH, 2022)
"Acetazolamide was the treatment option in 98."1.51Pediatric intracranial hypertension. Experience from 2 Tertiary Centers. ( Ajlan, AM; Al Abdulsalam, HK; Al Twaijri, WA; Al-Showaeir, DA; Albakr, AA; Aldabjan, HM; Aldegether, MS; Alhothali, WM; Almalki, FI; Altweijri, IS; Alwadei, AH; Bashiri, FA; Hamad, MH; Hassan, HH; Hassan, SM; Kentab, AY; Salih, MA, 2019)
"Patients with idiopathic intracranial hypertension commonly present with a headache, transient visual obscurations, and intracranial noises with some cranial nerves occasionally involved, most commonly CN VI."1.51Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report. ( Berry, B; Ghannam, M; Ghazaleh, D; Samara, A, 2019)
"To describe a new subtype of chronic daily headache in women of a specific age group."1.48A New Subtype of Chronic Daily Headache Presenting in Older Women. ( Rozen, TD, 2018)
"Acetazolamide was the drug of choice, with relatively low dosages used."1.39Pseudotumor cerebri in childhood and adolescence -- results of a Germany-wide ESPED-survey. ( Distelmaier, F; Mayatepek, E; Tibussek, D; von Kries, R, 2013)
"However, prompt diagnosis of idiopathic intracranial hypertension and initiation of medical therapy lead to improved symptoms and restored vision."1.33Idiopathic intracranial hypertension and sickle cell disease: two case reports. ( Discepola, M; Segal, L, 2005)
"A 30-year-old woman had bilateral anterior ischemic optic neuropathy after undergoing large-volume liposuction."1.32Bilateral anterior ischemic optic neuropathy after liposuction. ( Foroozan, R; Varon, J, 2004)
"Minocycline and obesity are recognized as precipitating factors in pseudotumor cerebri syndrome."1.31[Bilateral papilledema in young women: two case reports of benign intracranial hypertension?]. ( Cochener, B; Colin, J; Kling, F, 2002)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.11)18.7374
1990's5 (11.11)18.2507
2000's8 (17.78)29.6817
2010's22 (48.89)24.3611
2020's5 (11.11)2.80

Authors

AuthorsStudies
Costa, G1
Carta, F1
Ambrosio, FA1
Artese, A1
Ortuso, F1
Moraca, F1
Rocca, R1
Romeo, I1
Lupia, A1
Maruca, A1
Bagetta, D1
Catalano, R1
Vullo, D1
Alcaro, S1
Supuran, CT2
Thaller, M1
Wakerley, BR1
Abbott, S1
Tahrani, AA1
Mollan, SP1
Sinclair, AJ1
Souza, MNP1
Costa, BAL1
Santos, FRDR1
Fortini, I1
Bashiri, FA1
Al Abdulsalam, HK1
Hassan, SM1
Al Twaijri, WA1
Almalki, FI1
Kentab, AY1
Hamad, MH1
Alwadei, AH1
Al-Showaeir, DA1
Altweijri, IS1
Aldabjan, HM1
Aldegether, MS1
Albakr, AA1
Alhothali, WM1
Ajlan, AM1
Hassan, HH1
Salih, MA1
Yang, N1
Tanner, JA1
Zheng, BJ1
Watt, RM1
He, ML1
Lu, LY1
Jiang, JQ1
Shum, KT1
Lin, YP1
Wong, KL1
Lin, MCM1
Kung, HF1
Sun, H1
Huang, JD1
Marinho, CC1
Nicolato, AJPG1
Reis, VW1
Dos Santos, RC1
Silva, JC1
Faria, HP1
Machado-Coelho, GLL1
Sun, Y2
Zhang, N1
Wang, J2
Guo, Y1
Sun, B1
Liu, W1
Zhou, H1
Yang, C1
Wei, L1
Ball, S1
Dennis, JA1
Bedanie, G1
Nugent, K1
Hayek, AJ1
Scott, V1
Yau, P1
Zolfaghari, K1
Goldwater, M1
Almquist, J1
Arroliga, AC1
Ghamande, S1
Wu, Q1
Ma, W1
Shi, R1
Zhang, B1
Mao, X1
Zheng, W1
Sbhatu, DB1
Berhe, GG1
Hndeya, AG1
Abraha, HB1
Abdu, A1
Gebru, HA1
Taye, MG1
Mulugeta, A1
Weldemichael, MY1
Tekle, HT1
Kidanemariam, HG1
Surger, M1
Angelov, A1
Liebl, W1
Hookey, L1
Bertiger, G1
Johnson, KL1
Boules, M1
Ando, M1
Dahdal, DN1
Riedl, JM1
Posch, F1
Prager, G1
Eisterer, W1
Oehler, L1
Sliwa, T1
Wilthoner, K1
Petzer, A1
Pichler, P1
Hubmann, E1
Winder, T1
Burgstaller, S1
Korger, M1
Andel, J1
Greil, R1
Neumann, HJ1
Pecherstorfer, M1
Philipp-Abbrederis, K1
Djanani, A1
Gruenberger, B1
Laengle, F1
Wöll, E1
Gerger, A1
Evans, WE1
Raynor, HA1
Howie, W1
Lipton, RB1
Thomas, GJ1
Wing, RR1
Pavlovic, J1
Farris, SG1
Bond, DS1
Hepprich, M1
Antwi, K1
Waser, B1
Reubi, JC1
Wild, D1
Christ, ER1
Braüner Christensen, J1
Aasbrenn, M1
Sandoval Castillo, L1
Ekmann, A1
Giver Jensen, T1
Pressel, E1
Haxholdt Lunn, T1
Suetta, C1
Palm, H1
Mansour, FA1
Al-Mazrou, A1
Al-Mohanna, F1
Al-Alwan, M1
Ghebeh, H1
Brown-Johnson, C1
Safaeinili, N1
Zionts, D1
Holdsworth, LM1
Shaw, JG1
Asch, SM1
Mahoney, M1
Winget, M1
Luo, Y1
Shan, H1
Gao, X1
Qi, P1
Li, Y2
Li, B1
Rong, X1
Shen, B1
Zhang, H1
Lin, F1
Tang, Z1
Fang, Z1
Peng, Z1
Jimenez, JL1
Ayer, GB1
Klepov, VV1
Pace, KA1
Zur Loye, HC1
Acquaroni, M1
Svartz, G1
Pérez Coll, C1
Otludil, B1
Ayaz, S1
Hill, A1
Elakkad, A1
Kuban, J1
Sabir, S1
Odisio, B1
Huang, SY1
Mahvash, A1
Miller, E1
Kroll, MH1
Overman, M1
Tam, AL1
Gupta, S1
Sheth, RA1
Deandreis, D1
Guarneri, A1
Ceci, F1
Lillaz, B1
Bartoncini, S1
Oderda, M1
Nicolotti, DG1
Pilati, E1
Passera, R1
Zitella, A1
Bellò, M1
Parise, R1
Carlevato, R1
Ricardi, U1
Gontero, P1
Coyne, GO'1
Wang, L2
Zlott, J1
Juwara, L1
Covey, JM1
Beumer, JH1
Cristea, MC1
Newman, EM1
Koehler, S1
Nieva, JJ1
Garcia, AA1
Gandara, DR1
Miller, B1
Khin, S1
Miller, SB1
Steinberg, SM1
Rubinstein, L1
Parchment, RE1
Kinders, RJ1
Piekarz, RL1
Kummar, S1
Chen, AP1
Doroshow, JH1
Li, X2
Chen, J2
Gan, L1
Tian, Y1
Shi, B1
Yang, Y1
Li, G1
Wu, D1
Wen, A1
Wu, Y1
Zhou, X1
Koyappayil, A1
Chavan, SG1
Mohammadniaei, M1
Go, A1
Hwang, SY1
Lee, MH1
Kurokawa, Y1
Yamashita, K1
Kawabata, R1
Fujita, J1
Imamura, H1
Takeno, A1
Takahashi, T1
Yamasaki, M1
Eguchi, H1
Doki, Y1
Schulte, T1
Sala, BM1
Nilvebrant, J1
Nygren, PÅ1
Achour, A1
Shernyukov, A1
Agback, T1
Agback, P1
Karami, H1
Shariatifar, N1
Nazmara, S1
Moazzen, M1
Mahmoodi, B1
Mousavi Khaneghah, A1
Sinha, N1
Mukhopadhyay, S1
Sau, M1
Qi, Y1
Wan, M1
Abd El-Aty, AM1
Li, H2
Cao, L1
She, Y1
Shao, Y1
Jin, F1
Wang, S1
Melendez-Araújo, MS1
Lemos, KGE1
Arruda, SLM1
Dutra, ES1
de Carvalho, KMB1
de la Plaza Llamas, R1
Díaz Candelas, DA1
Ramia, JM1
Zhu, S1
Liu, Z1
Lu, J2
Xiang, Z1
Lan, J1
Liu, J1
Yu, M1
Chen, Y2
Sirajudeen, AAO1
Annuar, MSM1
Subramaniam, R1
Somme, F1
Montaz-Rosset, MS1
Averous, G1
Deur, J1
Goichot, B1
Bachellier, P1
Addeo, P1
Imperiale, A1
Xu, L1
Li, Z2
Song, S1
Chen, Q1
Mo, L1
Wang, C1
Fan, W1
Yan, Y1
Tong, X1
Yan, H1
Singh, A1
Chen, HC1
Chen, YF1
Lu, YJ1
Wong, KT1
Chu, CW1
Banijamali, AR1
Carvalho, AE1
Wakefield, JD1
Germano, P1
Barden, TC1
Tobin, JV1
Zimmer, DP1
Masferrer, JL1
Profy, AT1
Currie, MG1
Todd Milne, G1
Zhang, Y1
Yang, H1
Dang, Z1
Zhan, S1
Sun, C1
Hu, G1
Lin, Y1
Yuan, Q1
Karayağiz Muslu, G1
Özdemir, M1
Del Prete, S1
Nocentini, A1
Capasso, C1
Chagas, ATA1
Ludwig, S1
Pimentel, JDSM1
de Abreu, NL1
Nunez-Rodriguez, DL1
Leal, HG1
Kalapothakis, E1
Zhang, J1
Lin, L1
Dodig, D1
Kovačić, S1
Matana Kaštelan, Z1
Žuža, I1
Benić, F1
Slaven, J1
Miletić, D1
Rumboldt, Z1
Fernandez-Botran, R1
Wellmann, IA1
Une, C1
Méndez-Chacón, E1
Hernández de Rodas, E1
Bhandari, B1
Villagrán de Tercero, CI1
Nguyen, HTT1
Romano, F1
Wampfler, R1
Mühlethaler, K1
Tannich, E1
Oberli, A1
Yang, J1
Xiang, T1
Dai, L1
Zhao, X1
Ma, L1
Zuo, D1
Wei, B1
Sui, Y1
Xu, F1
Zheng, H1
Qiu, C1
Jin, H1
Kerwin, J1
Khan, I1
Rajasekhar, B1
Venkateshwaran, U1
Durairaj, N1
Divyapriya, G1
Nambi, IM1
Joseph, A1
Aliste, M1
Garrido, I1
Flores, P1
Hellín, P1
Vela, N1
Navarro, S1
Fenoll, J1
Namiki, H1
Caravedo, MA1
Mozo, K1
Morales, ML1
Smiley, H1
Stuart, J1
Tilley, DH1
Cabada, MM1
Berkowitz, E1
Kopelman, Y1
Kadosh, D1
Carasso, S1
Tiosano, B1
Kesler, A2
Geva-Zatorsky, N1
Rozen, TD1
Raggi, A1
Grazzi, L1
Bianchi Marzoli, S1
Ciasca, P1
Chiapparini, L1
Erbetta, A1
Faragò, G1
Leonardi, M1
D'Amico, D1
Samara, A1
Ghazaleh, D1
Berry, B1
Ghannam, M1
Sundholm, A1
Träisk, F1
Hellgren, K1
Lundvall, M1
Söderman, M1
Gustavsson, B1
Nilsson Remahl, I1
Tibussek, D1
Distelmaier, F1
von Kries, R1
Mayatepek, E1
Brosh, K1
Strassman, I1
Ranganathan, S1
Lee, SH1
Checkver, A1
Sklar, E1
Lam, BL1
Danton, GH1
Alperin, N1
Molobe, LT1
Shifa, J1
Silava, C1
Mojela, K1
Cainelli, F1
Vento, S1
Zingerman, B1
Herman-Edelstein, M1
Erman, A1
Bar Sheshet Itach, S1
Ori, Y1
Rozen-Zvi, B1
Gafter, U1
Chagnac, A1
Lin, WS1
Huang, CW1
Song, YS1
Yen, JH1
Kuo, PC1
Yeh, SR1
Lin, HY1
Fu, TF1
Wu, MS1
Wang, HD1
Wang, PY1
Thakore, RV1
Johnson, MA1
Krohel, GB2
Johnson, LN2
Rook, BS1
Phillips, PH1
Abdelfatah, MA1
Libien, J1
Kupersmith, MJ1
Blaner, W1
McDermott, MP1
Gao, S1
Liu, Y1
Corbett, J1
Wall, M1
Marton, E1
Feletti, A1
Mazzucco, GM1
Longatti, P1
Fraser, C1
Plant, GT1
Dessardo, NS1
Dessardo, S1
Sasso, A1
Sarunić, AV1
Dezulović, MS1
Belliveau, MJ1
ten Hove, MW1
Dolinsky, DH1
Armstrong, S1
Martínez-Varea, A1
Diago-Almela, VJ1
Abad-Carrascosa, A1
Perales-Marín, A1
Yang, L1
Hashemi, N1
Lee, AG1
Kling, F1
Cochener, B1
Colin, J1
Arsava, EM1
Uluc, K1
Nurlu, G1
Kansu, T1
ZARA, M2
Fage, JC1
STARR, HJ1
Foroozan, R1
Varon, J1
Segal, L1
Discepola, M1
Bassan, H1
Berkner, L1
Stolovitch, C1
Machner, B1
Neppert, B1
Paulsen, M1
Hofmann, C1
Sander, T1
Helmchen, C1
Mathew, NT1
Ravishankar, K1
Sanin, LC1
Hudgel, DW1
Thanakitcharu, S1
Demols, P1
Vilain, S1
Van Nechel, C1
Madsen, RW1
March, GA1
Pomeranz, HD1
Digre, KB1
Corbett, JJ1
Mayer, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Acetazolamide and Furosemide on Obesity-induced Glomerular Hyperfiltration[NCT01146288]13 participants (Actual)Interventional2010-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in GFR (ml/Min)

(NCT01146288)
Timeframe: baseline and after diuretics administration

,
Interventionml/min (Mean)
GFR before acetazolamide/furosemide administrationGFR after acetazolamide/furosemide administration
Acetazolamide151120
Furosemide152150

Renal Vascular Resistance (mm Hg/[ml/Min])

(NCT01146288)
Timeframe: baseline and after diuretics administration

,
Interventionmm Hg/[ml/min] (Mean)
before acetazolamide/furosemide administrationafter acetazolamide/furosemide administration
Acetazolamide0.0780.088
Furosemide0.0730.080

Reviews

5 reviews available for acetazolamide and Obesity

ArticleYear
Update on Idiopathic Intracranial Hypertension Management.
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:5 Suppl 1

    Topics: Acetazolamide; Headache; Humans; Intracranial Hypertension; Obesity; Pseudotumor Cerebri; Vision Dis

2022
[Idiopathic intracranial hypertension - Swedish consensus guidelines].
    Lakartidningen, 2019, May-15, Volume: 116

    Topics: Acetazolamide; Bariatric Surgery; Carbonic Anhydrase Inhibitors; Consensus; Critical Pathways; Diagn

2019
Pediatric pseudotumor cerebri.
    Current opinion in ophthalmology, 2016, Volume: 27, Issue:5

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Pressure; Child; Humans; Magnetic

2016
The syndrome of pseudotumour cerebri and idiopathic intracranial hypertension.
    Current opinion in neurology, 2011, Volume: 24, Issue:1

    Topics: Acetazolamide; Body Mass Index; Carbonic Anhydrase Inhibitors; Constriction, Pathologic; Humans; Int

2011
Pharmacologic treatment of sleep-disordered breathing.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3

    Topics: Acetazolamide; Antihypertensive Agents; Apnea; Bronchodilator Agents; Diuretics; Dyspnea; Evidence-B

1998

Trials

6 trials available for acetazolamide and Obesity

ArticleYear
    Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 2007, Aug-27, Volume: 119, Issue:34

    Topics: 3-Hydroxybutyric Acid; Acetazolamide; Acrylates; Administration, Intravenous; Adolescent; Adult; Aer

2007
Magnetic resonance imaging finding of empty sella in obesity related idiopathic intracranial hypertension is associated with enlarged sella turcica.
    Neuroradiology, 2013, Volume: 55, Issue:8

    Topics: Acetazolamide; Adult; Diuretics; Female; Humans; Hypertrophy; Magnetic Resonance Imaging; Male; Obes

2013
Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Diuretics; Furosemide; Glomerular Filtration Ra

2015
Pseudotumor cerebri: What We Have Learned from the Idiopathic Intracranial Hypertension Treatment Trial.
    Rhode Island medical journal (2013), 2016, May-02, Volume: 99, Issue:5

    Topics: Acetazolamide; Adolescent; Adult; Diuretics; Female; Humans; Male; Middle Aged; North America; Obesi

2016
Role of vitamin A metabolism in IIH: Results from the idiopathic intracranial hypertension treatment trial.
    Journal of the neurological sciences, 2017, Jan-15, Volume: 372

    Topics: Acetazolamide; Adult; Anticonvulsants; Carotenoids; Chromatography, High Pressure Liquid; Chromatogr

2017
The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri)
    Ophthalmology, 1998, Volume: 105, Issue:12

    Topics: Acetazolamide; Adult; Body Mass Index; Body Weight; Female; Humans; Middle Aged; Obesity; Papilledem

1998

Other Studies

34 other studies available for acetazolamide and Obesity

ArticleYear
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Anti-Obesity Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Com

2019
Managing idiopathic intracranial hypertension in pregnancy: practical advice.
    Practical neurology, 2022, Volume: 22, Issue:4

    Topics: Acetazolamide; Female; Humans; Intracranial Hypertension; Obesity; Pregnancy; Pseudotumor Cerebri; W

2022
Pediatric intracranial hypertension. Experience from 2 Tertiary Centers.
    Neurosciences (Riyadh, Saudi Arabia), 2019, Volume: 24, Issue:4

    Topics: Acetazolamide; Child; Child, Preschool; Diuretics; Female; Headache; Hospitals, Pediatric; Humans; I

2019
Antipsychotic pitfalls: idiopathic intracranial hypertension and antipsychotic-induced weight gain.
    BMJ case reports, 2020, Jun-30, Volume: 13, Issue:6

    Topics: Acetazolamide; Adult; Antipsychotic Agents; Depressive Disorder, Major; Drug Substitution; Female; H

2020
Risk factors for acute mountain sickness in travellers to Cusco, Peru: coca leaves, obesity and sex.
    Journal of travel medicine, 2022, 08-20, Volume: 29, Issue:5

    Topics: Acetazolamide; Acute Disease; Adult; Altitude; Altitude Sickness; Coca; Cohort Studies; Female; Huma

2022
"More Guts Than Brains?"-The Role of Gut Microbiota in Idiopathic Intracranial Hypertension.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2022, 03-01, Volume: 42, Issue:1

    Topics: Acetazolamide; Brain; Female; Gastrointestinal Microbiome; Humans; Obesity; Papilledema; Pseudotumor

2022
A New Subtype of Chronic Daily Headache Presenting in Older Women.
    Journal of women's health (2002), 2018, Volume: 27, Issue:2

    Topics: Acetazolamide; Cerebrospinal Fluid Pressure; Female; Head-Down Tilt; Headache Disorders; Humans; Mid

2018
The importance of specific rehabilitation for an obese patient with idiopathic intracranial hypertension: a case report.
    International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, 2018, Volume: 41, Issue:2

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Diet, Reducing; Female; Humans; Obesity; Papill

2018
Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report.
    Journal of medical case reports, 2019, Apr-19, Volume: 13, Issue:1

    Topics: Acetazolamide; Adult; Facial Paralysis; Female; Headache; Humans; Magnetic Resonance Imaging; Obesit

2019
Pseudotumor cerebri in childhood and adolescence -- results of a Germany-wide ESPED-survey.
    Klinische Padiatrie, 2013, Volume: 225, Issue:2

    Topics: Acetazolamide; Adolescent; Age Factors; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Comorbi

2013
Unilateral papilledema in pseudotumor cerebri.
    Seminars in ophthalmology, 2013, Volume: 28, Issue:4

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Intracranial Pressure; Obesity;

2013
Primary pseudotumor cerebri syndrome in a young obese African woman.
    The Israel Medical Association journal : IMAJ, 2014, Volume: 16, Issue:9

    Topics: Acetazolamide; Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Antihypertensive Agents; Diuretic

2014
Reduced Gut Acidity Induces an Obese-Like Phenotype in Drosophila melanogaster and in Mice.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Acetazolamide; Acid-Base Equilibrium; Animals; Carbonic Anhydrase Inhibitors; Drosophila melanogaste

2015
Normal Pressure Pseudotumor Cerebri: A Series of Six Patients.
    Turkish neurosurgery, 2017, Volume: 27, Issue:2

    Topics: Acetazolamide; Adult; Cerebrospinal Fluid Pressure; Female; Humans; Intracranial Hypertension; Neuro

2017
Pseudotumor cerebri in pediatric age: role of obesity in the management of neurological impairments.
    Nutritional neuroscience, 2008, Volume: 11, Issue:1

    Topics: Acetazolamide; Adolescent; Cerebrospinal Fluid; Child; Child, Preschool; Cranial Nerve Diseases; Die

2008
Pediatric idiopathic intracranial hypertension: clinical and demographic features.
    Collegium antropologicum, 2010, Volume: 34 Suppl 2

    Topics: Acetazolamide; Adolescent; Child; Diuretics; Female; Humans; Male; Obesity; Ophthalmoscopy; Papilled

2010
Idiopathic intracranial hypertension.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011, Nov-08, Volume: 183, Issue:16

    Topics: Acetazolamide; Anti-Bacterial Agents; Antidepressive Agents; Body Mass Index; Cerebrospinal Fluid Sh

2011
An 8-year-old girl with headache and syncope.
    Pediatric annals, 2011, Volume: 40, Issue:12

    Topics: Acetazolamide; Child; Diuretics; Female; Headache; Humans; Insulin Resistance; Obesity; Pseudotumor

2011
Progressive visual loss in a pregnant woman with idiopathic intracranial hypertension.
    European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 163, Issue:1

    Topics: Acetazolamide; Adult; Female; Humans; Obesity; Pregnancy; Pregnancy Complications; Pseudotumor Cereb

2012
Intracranial complications of idiopathic intracranial hypertension.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2012, Volume: 47, Issue:6

    Topics: Acetazolamide; Adult; Anticoagulants; Cerebral Veins; Drug Therapy, Combination; Female; Humans; Mag

2012
[Bilateral papilledema in young women: two case reports of benign intracranial hypertension?].
    Journal francais d'ophtalmologie, 2002, Volume: 25, Issue:8

    Topics: Acetazolamide; Adolescent; Adult; Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Female; Fluo

2002
Electrophysiological evidence of trigeminal neuropathy in pseudotumor cerebri.
    Journal of neurology, 2002, Volume: 249, Issue:11

    Topics: Acetazolamide; Adult; Cerebrospinal Fluid Shunts; Female; Humans; Intracranial Hypertension; Neural

2002
[New treatment of obesity].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Dec-06, Volume: 32, Issue:71

    Topics: Acetazolamide; Amphetamine; Amphetamines; Obesity; Thyroid (USP); Thyroid Gland; Thyroid Hormones

1956
[New treatment of obesity].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Dec-06, Volume: 32, Issue:71

    Topics: Acetazolamide; Amphetamine; Amphetamines; Obesity; Thyroid (USP); Thyroid Gland; Thyroid Hormones

1956
[New treatment of obesity].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Dec-06, Volume: 32, Issue:71

    Topics: Acetazolamide; Amphetamine; Amphetamines; Obesity; Thyroid (USP); Thyroid Gland; Thyroid Hormones

1956
[New treatment of obesity].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Dec-06, Volume: 32, Issue:71

    Topics: Acetazolamide; Amphetamine; Amphetamines; Obesity; Thyroid (USP); Thyroid Gland; Thyroid Hormones

1956
[Chlorothiazide and obesity of women].
    France Medecine, 1959, Volume: 22, Issue:2

    Topics: Acetazolamide; Obesity

1959
PSEUDOTUMOR CEREBRI. REPORT OF SIX CASES COMPARED WITH ONE CASE OF PSEUDOPAPILLEDEMA.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Acetazolamide; Brain Diseases; Brain Neoplasms; Chlorothiazide; Diagnosis; Diet, Sodium-Restricted;

1964
Bilateral anterior ischemic optic neuropathy after liposuction.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2004, Volume: 24, Issue:3

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Jugular Veins; Lipectomy; Magne

2004
Idiopathic intracranial hypertension and sickle cell disease: two case reports.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2005, Volume: 40, Issue:6

    Topics: Acetazolamide; Adolescent; Adult; Anemia, Sickle Cell; Carbonic Anhydrase Inhibitors; Female; Headac

2005
Asymptomatic idiopathic intracranial hypertension in children.
    Acta neurologica Scandinavica, 2008, Volume: 118, Issue:4

    Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Diuretics; Female; Humans; Male; Ob

2008
Pseudotumor cerebri as a reversible side effect of all-trans retinoic acid treatment in acute promyelocytic leukaemia.
    European journal of neurology, 2008, Volume: 15, Issue:7

    Topics: Acetazolamide; Adult; Anticonvulsants; Antineoplastic Agents; Female; Humans; Idarubicin; Leukemia,

2008
Coexistence of migraine and idiopathic intracranial hypertension without papilledema.
    Neurology, 1996, Volume: 46, Issue:5

    Topics: Acetazolamide; Adolescent; Adult; Dihydroergotamine; Diuretics; Ergotamine; Female; Follow-Up Studie

1996
[Association of idiopathic intracranial hypertension-Arnold-Chiari deformity: danger!].
    Bulletin de la Societe belge d'ophtalmologie, 1998, Volume: 268

    Topics: Acetazolamide; Adult; Anticonvulsants; Arnold-Chiari Malformation; Eye Movements; Female; Humans; In

1998
Weight loss, acetazolamide, and pseudotumor cerebri.
    Ophthalmology, 1999, Volume: 106, Issue:9

    Topics: Acetazolamide; Body Weight; Humans; Obesity; Papilledema; Pseudotumor Cerebri; Weight Loss

1999
Pseudotumor cerebri in men.
    Archives of neurology, 1988, Volume: 45, Issue:8

    Topics: Acetazolamide; Adolescent; Adult; Body Weight; Female; Humans; Hypertension; Male; Middle Aged; Obes

1988
[Therapy of Hyperostosis Frontalis Interna].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Acetazolamide; Diabetes Mellitus; Female; Humans; Hyperostosis Frontalis Interna; Hypertension; Obes

1969