acetazolamide has been researched along with Neoplasms in 62 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (4.84) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 20 (32.26) | 29.6817 |
| 2010's | 30 (48.39) | 24.3611 |
| 2020's | 9 (14.52) | 2.80 |
| Authors | Studies |
|---|---|
| Vullo, D | 15 |
| Franchi, M | 1 |
| Gallori, E | 1 |
| Pastorek, J | 2 |
| Scozzafava, A | 18 |
| Pastorekova, S | 3 |
| Supuran, CT | 49 |
| Winum, JY | 6 |
| Casini, A | 2 |
| Montero, JL | 5 |
| Lehtonen, JM | 1 |
| Parkkila, S | 1 |
| Cecchi, A | 3 |
| Innocenti, A | 12 |
| Almajan, GL | 1 |
| Puccetti, L | 3 |
| Manole, G | 1 |
| Barbuceanu, S | 1 |
| Saramet, I | 1 |
| Fasolis, G | 2 |
| Gamberi, A | 1 |
| Thiry, A | 1 |
| Ledecq, M | 1 |
| Dogné, JM | 2 |
| Wouters, J | 1 |
| Masereel, B | 2 |
| Saczewski, F | 2 |
| Sławiński, J | 5 |
| Kornicka, A | 2 |
| Brzozowski, Z | 3 |
| Pomarnacka, E | 2 |
| De Simone, G | 3 |
| Vitale, RM | 2 |
| Di Fiore, A | 1 |
| Pedone, C | 1 |
| Santos, MA | 1 |
| Marques, S | 1 |
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Rami, M | 1 |
| Temperini, C | 1 |
| D'Ambrosio, K | 1 |
| Carta, F | 7 |
| Maresca, A | 3 |
| Lopez, M | 2 |
| Paul, B | 1 |
| Hofmann, A | 1 |
| Morizzi, J | 2 |
| Wu, QK | 1 |
| Charman, SA | 3 |
| Poulsen, SA | 4 |
| Bornaghi, LF | 2 |
| Knaus, EE | 1 |
| Salmon, AJ | 1 |
| Williams, ML | 1 |
| Aggarwal, M | 1 |
| McKenna, R | 3 |
| Masini, E | 3 |
| Alafeefy, AM | 3 |
| Isik, S | 1 |
| Abdel-Aziz, HA | 2 |
| Ashour, AE | 1 |
| Al-Jaber, NA | 1 |
| Carradori, S | 2 |
| De Monte, C | 1 |
| D'Ascenzio, M | 2 |
| Secci, D | 2 |
| Celik, G | 1 |
| Ceruso, M | 5 |
| Carroux, CJ | 1 |
| Rankin, GM | 1 |
| Moeker, J | 1 |
| Katneni, K | 1 |
| Żołnowska, B | 2 |
| Pogorzelska, A | 2 |
| Chojnacki, J | 1 |
| Grandane, A | 3 |
| Tanc, M | 2 |
| Zalubovskis, R | 4 |
| Brożewicz, K | 1 |
| Sarikaya, B | 1 |
| Bozdag, M | 3 |
| Pinard, M | 1 |
| Dudutienė, V | 1 |
| Matulienė, J | 1 |
| Smirnov, A | 1 |
| Timm, DD | 1 |
| Zubrienė, A | 1 |
| Baranauskienė, L | 1 |
| Morkūnaite, V | 1 |
| Smirnovienė, J | 1 |
| Michailovienė, V | 1 |
| Juozapaitienė, V | 1 |
| Mickevičiūtė, A | 1 |
| Kazokaitė, J | 1 |
| Bakšytė, S | 1 |
| Kasiliauskaitė, A | 1 |
| Jachno, J | 1 |
| Revuckienė, J | 1 |
| Kišonaitė, M | 1 |
| Pilipuitytė, V | 1 |
| Ivanauskaitė, E | 1 |
| Milinavičiūtė, G | 1 |
| Smirnovas, V | 1 |
| Petrikaitė, V | 1 |
| Kairys, V | 1 |
| Petrauskas, V | 1 |
| Norvaišas, P | 1 |
| Lingė, D | 1 |
| Gibieža, P | 1 |
| Capkauskaitė, E | 1 |
| Zakšauskas, A | 1 |
| Kazlauskas, E | 1 |
| Manakova, E | 1 |
| Gražulis, S | 1 |
| Ladbury, JE | 1 |
| Matulis, D | 1 |
| Khloya, P | 1 |
| Ram, S | 2 |
| Sharma, PK | 3 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 3 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 3 |
| Cornelio, B | 2 |
| Laronze-Cochard, M | 2 |
| Ferraroni, M | 1 |
| Rance, GA | 1 |
| Khlobystov, AN | 1 |
| Fontana, A | 2 |
| Sapi, J | 2 |
| Riafrecha, LE | 1 |
| Bua, S | 2 |
| Colinas, PA | 1 |
| Altamimi, AM | 2 |
| Kocyigit, UM | 1 |
| Budak, Y | 1 |
| Gürdere, MB | 1 |
| Tekin, Ş | 1 |
| Köprülü, TK | 1 |
| Ertürk, F | 1 |
| Özcan, K | 1 |
| Gülçin, İ | 1 |
| Ceylan, M | 1 |
| Kumar, R | 1 |
| Del Prete, S | 2 |
| Capasso, C | 3 |
| Fragai, M | 1 |
| Comito, G | 1 |
| Di Cesare Mannelli, L | 1 |
| Gualdani, R | 1 |
| Calderone, V | 1 |
| Louka, A | 1 |
| Richichi, B | 1 |
| Francesconi, O | 1 |
| Angeli, A | 4 |
| Nocentini, A | 6 |
| Gratteri, P | 2 |
| Chiarugi, P | 1 |
| Ghelardini, C | 1 |
| Tadini-Buoninsegni, F | 1 |
| Nativi, C | 1 |
| Krasavin, M | 1 |
| Shetnev, A | 1 |
| Sharonova, T | 1 |
| Baykov, S | 1 |
| Kalinin, S | 1 |
| Sharoyko, V | 1 |
| Poli, G | 2 |
| Tuccinardi, T | 2 |
| Presnukhina, S | 1 |
| Tennikova, TB | 1 |
| Miambo, R | 1 |
| De Grandis, M | 1 |
| Riccioni, R | 1 |
| Borisova, B | 1 |
| Dontchev, D | 1 |
| Machado, C | 1 |
| Zara, S | 1 |
| Guglielmi, P | 1 |
| Cirilli, R | 1 |
| Pierini, M | 1 |
| Said, MA | 1 |
| Eldehna, WM | 1 |
| Fahim, SH | 1 |
| Bonardi, A | 1 |
| Elgazar, AA | 1 |
| Kryštof, V | 1 |
| Soliman, DH | 1 |
| Abou-Seri, SM | 1 |
| Domračeva, I | 1 |
| Andring, JT | 1 |
| Fouch, M | 1 |
| Akocak, S | 1 |
| Ilies, MA | 1 |
| Singh, P | 1 |
| Sridhar Goud, N | 1 |
| Swain, B | 1 |
| Kumar Sahoo, S | 1 |
| Choli, A | 1 |
| Singh Kushwah, B | 1 |
| Madhavi Yaddanapudi, V | 1 |
| Arifuddin, M | 1 |
| Wojtkowiak, K | 3 |
| Michalczyk, M | 3 |
| Zierkiewicz, W | 3 |
| Jezierska, A | 3 |
| Panek, JJ | 3 |
| Huwaimel, BI | 1 |
| Jonnalagadda, SK | 1 |
| Jonnalagadda, S | 1 |
| Kumari, S | 1 |
| Trippier, PC | 1 |
| Kumar, A | 1 |
| Arya, P | 1 |
| Sharma, V | 1 |
| Giovannuzzi, S | 1 |
| Raghav, N | 1 |
| Yang, N | 1 |
| Tanner, JA | 1 |
| Zheng, BJ | 1 |
| Watt, RM | 1 |
| He, ML | 1 |
| Lu, LY | 1 |
| Jiang, JQ | 1 |
| Shum, KT | 1 |
| Lin, YP | 1 |
| Wong, KL | 1 |
| Lin, MCM | 1 |
| Kung, HF | 1 |
| Sun, H | 1 |
| Huang, JD | 1 |
| Marinho, CC | 1 |
| Nicolato, AJPG | 1 |
| Reis, VW | 1 |
| Dos Santos, RC | 1 |
| Silva, JC | 1 |
| Faria, HP | 1 |
| Machado-Coelho, GLL | 1 |
| Sun, Y | 2 |
| Zhang, N | 1 |
| Wang, J | 3 |
| Guo, Y | 1 |
| Sun, B | 1 |
| Liu, W | 1 |
| Zhou, H | 1 |
| Yang, C | 1 |
| Wei, L | 1 |
| Ball, S | 1 |
| Dennis, JA | 1 |
| Bedanie, G | 1 |
| Nugent, K | 1 |
| Hayek, AJ | 1 |
| Scott, V | 1 |
| Yau, P | 1 |
| Zolfaghari, K | 1 |
| Goldwater, M | 1 |
| Almquist, J | 1 |
| Arroliga, AC | 1 |
| Ghamande, S | 1 |
| Wu, Q | 1 |
| Ma, W | 1 |
| Shi, R | 1 |
| Zhang, B | 1 |
| Mao, X | 1 |
| Zheng, W | 1 |
| Sbhatu, DB | 1 |
| Berhe, GG | 1 |
| Hndeya, AG | 1 |
| Abraha, HB | 1 |
| Abdu, A | 1 |
| Gebru, HA | 1 |
| Taye, MG | 1 |
| Mulugeta, A | 1 |
| Weldemichael, MY | 1 |
| Tekle, HT | 1 |
| Kidanemariam, HG | 1 |
| Surger, M | 1 |
| Angelov, A | 1 |
| Liebl, W | 1 |
| Hookey, L | 1 |
| Bertiger, G | 1 |
| Johnson, KL | 1 |
| Boules, M | 1 |
| Ando, M | 1 |
| Dahdal, DN | 1 |
| Riedl, JM | 1 |
| Posch, F | 1 |
| Prager, G | 1 |
| Eisterer, W | 1 |
| Oehler, L | 1 |
| Sliwa, T | 1 |
| Wilthoner, K | 1 |
| Petzer, A | 1 |
| Pichler, P | 1 |
| Hubmann, E | 1 |
| Winder, T | 1 |
| Burgstaller, S | 1 |
| Korger, M | 1 |
| Andel, J | 1 |
| Greil, R | 1 |
| Neumann, HJ | 1 |
| Pecherstorfer, M | 1 |
| Philipp-Abbrederis, K | 1 |
| Djanani, A | 1 |
| Gruenberger, B | 1 |
| Laengle, F | 1 |
| Wöll, E | 1 |
| Gerger, A | 1 |
| Evans, WE | 1 |
| Raynor, HA | 1 |
| Howie, W | 1 |
| Lipton, RB | 1 |
| Thomas, GJ | 1 |
| Wing, RR | 1 |
| Pavlovic, J | 1 |
| Farris, SG | 1 |
| Bond, DS | 1 |
| Hepprich, M | 1 |
| Antwi, K | 1 |
| Waser, B | 1 |
| Reubi, JC | 1 |
| Wild, D | 1 |
| Christ, ER | 1 |
| Braüner Christensen, J | 1 |
| Aasbrenn, M | 1 |
| Sandoval Castillo, L | 1 |
| Ekmann, A | 1 |
| Giver Jensen, T | 1 |
| Pressel, E | 1 |
| Haxholdt Lunn, T | 1 |
| Suetta, C | 1 |
| Palm, H | 1 |
| Mansour, FA | 1 |
| Al-Mazrou, A | 1 |
| Al-Mohanna, F | 1 |
| Al-Alwan, M | 1 |
| Ghebeh, H | 1 |
| Brown-Johnson, C | 1 |
| Safaeinili, N | 1 |
| Zionts, D | 1 |
| Holdsworth, LM | 1 |
| Shaw, JG | 1 |
| Asch, SM | 1 |
| Mahoney, M | 1 |
| Winget, M | 1 |
| Luo, Y | 1 |
| Shan, H | 1 |
| Gao, X | 1 |
| Qi, P | 1 |
| Li, B | 1 |
| Rong, X | 1 |
| Shen, B | 1 |
| Zhang, H | 1 |
| Lin, F | 1 |
| Tang, Z | 1 |
| Fang, Z | 1 |
| Peng, Z | 1 |
| Jimenez, JL | 1 |
| Ayer, GB | 1 |
| Klepov, VV | 1 |
| Pace, KA | 1 |
| Zur Loye, HC | 1 |
| Acquaroni, M | 1 |
| Svartz, G | 1 |
| Pérez Coll, C | 1 |
| Otludil, B | 1 |
| Ayaz, S | 1 |
| Hill, A | 1 |
| Elakkad, A | 1 |
| Kuban, J | 1 |
| Sabir, S | 1 |
| Odisio, B | 1 |
| Huang, SY | 1 |
| Mahvash, A | 1 |
| Miller, E | 1 |
| Kroll, MH | 1 |
| Overman, M | 1 |
| Tam, AL | 1 |
| Gupta, S | 1 |
| Sheth, RA | 1 |
| Deandreis, D | 1 |
| Guarneri, A | 1 |
| Ceci, F | 1 |
| Lillaz, B | 1 |
| Bartoncini, S | 1 |
| Oderda, M | 1 |
| Nicolotti, DG | 1 |
| Pilati, E | 1 |
| Passera, R | 1 |
| Zitella, A | 1 |
| Bellò, M | 1 |
| Parise, R | 1 |
| Carlevato, R | 1 |
| Ricardi, U | 1 |
| Gontero, P | 1 |
| Coyne, GO' | 1 |
| Wang, L | 2 |
| Zlott, J | 1 |
| Juwara, L | 1 |
| Covey, JM | 1 |
| Beumer, JH | 1 |
| Cristea, MC | 1 |
| Newman, EM | 1 |
| Koehler, S | 1 |
| Nieva, JJ | 1 |
| Garcia, AA | 1 |
| Gandara, DR | 1 |
| Miller, B | 1 |
| Khin, S | 1 |
| Miller, SB | 1 |
| Steinberg, SM | 1 |
| Rubinstein, L | 1 |
| Parchment, RE | 1 |
| Kinders, RJ | 1 |
| Piekarz, RL | 1 |
| Kummar, S | 1 |
| Chen, AP | 1 |
| Doroshow, JH | 1 |
| Li, X | 2 |
| Gan, L | 1 |
| Tian, Y | 1 |
| Shi, B | 1 |
| Yang, Y | 1 |
| Li, G | 1 |
| Wu, D | 1 |
| Wen, A | 1 |
| Wu, Y | 1 |
| Zhou, X | 1 |
| Koyappayil, A | 1 |
| Chavan, SG | 1 |
| Mohammadniaei, M | 1 |
| Go, A | 1 |
| Hwang, SY | 1 |
| Lee, MH | 1 |
| Kurokawa, Y | 1 |
| Yamashita, K | 1 |
| Kawabata, R | 1 |
| Fujita, J | 1 |
| Imamura, H | 1 |
| Takeno, A | 1 |
| Takahashi, T | 1 |
| Yamasaki, M | 1 |
| Eguchi, H | 1 |
| Doki, Y | 1 |
| Schulte, T | 1 |
| Sala, BM | 1 |
| Nilvebrant, J | 1 |
| Nygren, PÅ | 1 |
| Achour, A | 1 |
| Shernyukov, A | 1 |
| Agback, T | 1 |
| Agback, P | 1 |
| Karami, H | 1 |
| Shariatifar, N | 1 |
| Nazmara, S | 1 |
| Moazzen, M | 1 |
| Mahmoodi, B | 1 |
| Mousavi Khaneghah, A | 1 |
| Sinha, N | 1 |
| Mukhopadhyay, S | 1 |
| Sau, M | 1 |
| Qi, Y | 1 |
| Wan, M | 1 |
| Abd El-Aty, AM | 1 |
| Li, H | 2 |
| Cao, L | 1 |
| She, Y | 1 |
| Shao, Y | 1 |
| Jin, F | 1 |
| Wang, S | 1 |
| Melendez-Araújo, MS | 1 |
| Lemos, KGE | 1 |
| Arruda, SLM | 1 |
| Dutra, ES | 1 |
| de Carvalho, KMB | 1 |
| de la Plaza Llamas, R | 1 |
| Díaz Candelas, DA | 1 |
| Ramia, JM | 1 |
| Zhu, S | 1 |
| Liu, Z | 1 |
| Lu, J | 2 |
| Xiang, Z | 1 |
| Lan, J | 1 |
| Liu, J | 1 |
| Yu, M | 1 |
| Chen, Y | 2 |
| Sirajudeen, AAO | 1 |
| Annuar, MSM | 1 |
| Subramaniam, R | 1 |
| Somme, F | 1 |
| Montaz-Rosset, MS | 1 |
| Averous, G | 1 |
| Deur, J | 1 |
| Goichot, B | 1 |
| Bachellier, P | 1 |
| Addeo, P | 1 |
| Imperiale, A | 1 |
| Xu, L | 1 |
| Li, Z | 2 |
| Song, S | 1 |
| Chen, Q | 1 |
| Mo, L | 1 |
| Wang, C | 1 |
| Fan, W | 1 |
| Yan, Y | 1 |
| Tong, X | 1 |
| Yan, H | 1 |
| Singh, A | 1 |
| Chen, HC | 1 |
| Chen, YF | 1 |
| Lu, YJ | 1 |
| Wong, KT | 1 |
| Chu, CW | 1 |
| Banijamali, AR | 1 |
| Carvalho, AE | 1 |
| Wakefield, JD | 1 |
| Germano, P | 1 |
| Barden, TC | 1 |
| Tobin, JV | 1 |
| Zimmer, DP | 1 |
| Masferrer, JL | 1 |
| Profy, AT | 1 |
| Currie, MG | 1 |
| Todd Milne, G | 1 |
| Zhang, Y | 1 |
| Yang, H | 1 |
| Dang, Z | 1 |
| Zhan, S | 1 |
| Sun, C | 1 |
| Hu, G | 1 |
| Lin, Y | 1 |
| Yuan, Q | 1 |
| Karayağiz Muslu, G | 1 |
| Özdemir, M | 1 |
| Chagas, ATA | 1 |
| Ludwig, S | 1 |
| Pimentel, JDSM | 1 |
| de Abreu, NL | 1 |
| Nunez-Rodriguez, DL | 1 |
| Leal, HG | 1 |
| Kalapothakis, E | 1 |
| Zhang, J | 1 |
| Lin, L | 1 |
| Dodig, D | 1 |
| Kovačić, S | 1 |
| Matana Kaštelan, Z | 1 |
| Žuža, I | 1 |
| Benić, F | 1 |
| Slaven, J | 1 |
| Miletić, D | 1 |
| Rumboldt, Z | 1 |
| Fernandez-Botran, R | 1 |
| Wellmann, IA | 1 |
| Une, C | 1 |
| Méndez-Chacón, E | 1 |
| Hernández de Rodas, E | 1 |
| Bhandari, B | 1 |
| Villagrán de Tercero, CI | 1 |
| Nguyen, HTT | 1 |
| Romano, F | 1 |
| Wampfler, R | 1 |
| Mühlethaler, K | 1 |
| Tannich, E | 1 |
| Oberli, A | 1 |
| Yang, J | 1 |
| Xiang, T | 1 |
| Dai, L | 1 |
| Zhao, X | 1 |
| Ma, L | 1 |
| Zuo, D | 1 |
| Wei, B | 1 |
| Sui, Y | 1 |
| Xu, F | 1 |
| Zheng, H | 1 |
| Qiu, C | 1 |
| Jin, H | 1 |
| Kerwin, J | 1 |
| Khan, I | 1 |
| Rajasekhar, B | 1 |
| Venkateshwaran, U | 1 |
| Durairaj, N | 1 |
| Divyapriya, G | 1 |
| Nambi, IM | 1 |
| Joseph, A | 1 |
| Aliste, M | 1 |
| Garrido, I | 1 |
| Flores, P | 1 |
| Hellín, P | 1 |
| Vela, N | 1 |
| Navarro, S | 1 |
| Fenoll, J | 1 |
| Kim, JH | 1 |
| Verwilst, P | 1 |
| Won, M | 1 |
| Lee, J | 1 |
| Sessler, JL | 1 |
| Han, J | 1 |
| Kim, JS | 1 |
| Liu, S | 2 |
| Luo, X | 1 |
| Xu, P | 1 |
| Hu, Y | 1 |
| Leitans, J | 1 |
| Kazaks, A | 1 |
| Balode, A | 1 |
| Ivanova, J | 1 |
| Tars, K | 1 |
| Lammoglia, JJ | 1 |
| Mericq, V | 1 |
| Cianchi, F | 1 |
| Vinci, MC | 1 |
| Peruzzi, B | 1 |
| De Giuli, P | 1 |
| Perigli, G | 1 |
| Papucci, L | 1 |
| Pini, A | 1 |
| ZANDER-PRINCIPATI, GE | 2 |
| KUZMA, JF | 2 |
| Ritland, JS | 1 |
| Egge, K | 1 |
| Lydersen, S | 1 |
| Juul, R | 1 |
| Semb, SO | 1 |
| Stöger, R | 1 |
1 review available for acetazolamide and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
1 trial available for acetazolamide and Neoplasms
60 other studies available for acetazolamide and Neoplasms
| Article | Year |
|---|---|
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.
Topics: Animals; Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydras | 2003 |
Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anh | 2003 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.
Topics: Amino Acid Sequence; Animals; Carbonic Anhydrase Inhibitors; Cytosol; Drug Design; Humans; Hydrogen- | 2004 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.
Topics: Benzolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic An | 2004 |
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carb | 2005 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carb | 2005 |
Indanesulfonamides as carbonic anhydrase inhibitors. Toward structure-based design of selective inhibitors of the tumor-associated isozyme CA IX.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dru | 2006 |
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.
Topics: Carbonic Anhydrase Inhibitors; Cell Hypoxia; Cell Membrane; Cytosol; Humans; Isoenzymes; Molecular S | 2006 |
Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX.
Topics: Antigens, Neoplasm; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Car | 2006 |
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties.
Topics: Carbonic Anhydrase Inhibitors; Cell Membrane; Cytosol; Humans; Hydroxamic Acids; Indicators and Reag | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.
Topics: Amines; Carbonic Anhydrase Inhibitors; Copper; Heterocyclic Compounds; Isoenzymes; Neoplasms; Sulfon | 2008 |
Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
Topics: Benzenesulfonamides; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cytosol; Hum | 2008 |
Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII.
Topics: Amino Acid Sequence; Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhyd | 2008 |
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors.
Topics: Antigens, Neoplasm; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Hu | 2009 |
Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II.
Topics: Carbonic Anhydrase Inhibitors; Cytosol; Isoenzymes; Magnetic Resonance Spectroscopy; Neoplasms; Spec | 2009 |
S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Cell Membrane Permeability; Cr | 2009 |
Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane Permeability; Glycoconjugates; Hum | 2010 |
Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carb | 2010 |
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carb | 2011 |
Synthesis of glycoconjugate carbonic anhydrase inhibitors by ruthenium-catalysed azide-alkyne 1,3-dipolar cycloaddition.
Topics: Alkynes; Antineoplastic Agents; Azides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysi | 2011 |
Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.
Topics: Animals; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Glaucoma; Humans; Intraocular Pressu | 2012 |
Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII.
Topics: Acrylamide; Antigens, Neoplasm; Antineoplastic Agents; Benzenesulfonamides; Carbonic Anhydrase Inhib | 2013 |
Salen and tetrahydrosalen derivatives act as effective inhibitors of the tumor-associated carbonic anhydrase XII--a new scaffold for designing isoform-selective inhibitors.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Drug Design; Enzyme Activation; Ethylenediamines | 2013 |
A prodrug approach toward cancer-related carbonic anhydrase inhibition.
Topics: Antigens, Neoplasm; Caco-2 Cells; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anh | 2013 |
Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associat
Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anh | 2014 |
Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carb | 2014 |
6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carb | 2014 |
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane; Dose-Response Relationship, Drug; | 2014 |
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carb | 2014 |
A class of 4-sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.
Topics: Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Crystallography, X-Ray; | 2014 |
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.
Topics: Benzene; Calorimetry; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Carbonic | 2014 |
Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.
Topics: Acetazolamide; Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase I | 2015 |
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.
Topics: Carbonic Anhydrase Inhibitors; Catalysis; Crystallography, X-Ray; Drug Design; Humans; Isoenzymes; M | 2016 |
Synthesis and carbonic anhydrase inhibitory effects of new N-glycosylsulfonamides incorporating the phenol moiety.
Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Humans; Neoplasms; Pheno | 2016 |
Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Coumari | 2017 |
Synthesis, characterization, anticancer, antimicrobial and carbonic anhydrase inhibition profiles of novel (3aR,4S,7R,7aS)-2-(4-((E)-3-(3-aryl)acryloyl) phenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione derivatives.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Carbonic Anhy | 2017 |
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors.
Topics: Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell | 2017 |
Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Humans; Kinetics; Neoplas | 2017 |
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX).
Topics: Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Cell Line, Tumor; Drug | 2017 |
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line; Cell Line, Tum | 2019 |
5-Arylisothiazol-3(2H)-one-1,(1)-(di)oxides: A new class of selective tumor-associated carbonic anhydrases (hCA IX and XII) inhibitors.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Humans; Neoplasms; Spectr | 2019 |
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Car | 2020 |
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation.
Topics: Antineoplastic Agents; Azo Compounds; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Proli | 2020 |
Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Car | 2020 |
Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone.
Topics: Acetazolamide; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Catalytic Domain | 2020 |
Synthesis of a new series of quinoline/pyridine indole-3-sulfonamide hybrids as selective carbonic anhydrase IX inhibitors.
Topics: Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Humans; Indoles; Isoenzyme | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Chalcogens; Humans; Ligands; Ne | 2022 |
Selective carbonic anhydrase IX and XII inhibitors based around a functionalized coumarin scaffold.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Coumarins; Humans; Molecular St | 2023 |
Potent inhibitors of tumor associated carbonic anhydrases endowed with cathepsin B inhibition.
Topics: Acetazolamide; Carbonic Anhydrase I; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cathepsin B | 2023 |
A Small Molecule Strategy for Targeting Cancer Stem Cells in Hypoxic Microenvironments and Preventing Tumorigenesis.
Topics: Acetazolamide; Animals; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; | 2021 |
Acetazolamide-Loaded pH-Responsive Nanoparticles Alleviating Tumor Acidosis to Enhance Chemotherapy Effects.
Topics: Acetazolamide; Acidosis; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc | 2019 |
Novel antibody to a carbonic anhydrase: patent evaluation of WO2011138279A1.
Topics: Acetazolamide; Animals; Antibodies; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic A | 2013 |
Efficient Expression and Crystallization System of Cancer-Associated Carbonic Anhydrase Isoform IX.
Topics: Acetazolamide; Antigens, Neoplasm; Antineoplastic Agents; Baculoviridae; Carbonic Anhydrase Inhibito | 2015 |
Familial tumoral calcinosis caused by a novel FGF23 mutation: response to induction of tubular renal acidosis with acetazolamide and the non-calcium phosphate binder sevelamer.
Topics: Acetazolamide; Acidosis, Renal Tubular; Calcinosis; Chelating Agents; Child, Preschool; Diuretics; D | 2009 |
Selective inhibition of carbonic anhydrase IX decreases cell proliferation and induces ceramide-mediated apoptosis in human cancer cells.
Topics: Acetazolamide; Antigens, Neoplasm; Apoptosis; Blotting, Western; Carbonic Anhydrase Inhibitors; Carb | 2010 |
ZIRCONIUM CITRATE REDUCES SR-90 BODY BURDEN.
Topics: Acetazolamide; Animals; Body Burden; Citrates; Citric Acid; Metabolism; Mice; Neoplasms; Neoplasms, | 1964 |
REDUCTION OF STRONTIUM-90 BONE CANCER BY ZIRCONIUM CITRATE.
Topics: Acetazolamide; Animals; Bone Neoplasms; Chelating Agents; Citrates; Citric Acid; Metabolism; Mice; N | 1964 |
Exfoliative glaucoma and primary open-angle glaucoma: associations with death causes and comorbidity.
Topics: Acetazolamide; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cause of Death; Cerebrovascul | 2004 |
[Directed internal cancer therapy. Combined hyperergization therapy].
Topics: Acetazolamide; Calcium; Choline; Female; Humans; Male; Middle Aged; Neoplasms; Thyroid Hormones | 1967 |