acetazolamide has been researched along with Myotonia in 11 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Myotonia: Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of MYOTONIC DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During acetazolamide treatment, symptoms and signs of myotonia decreased in our children." | 7.80 | Clinical experience with long-term acetazolamide treatment in children with nondystrophic myotonias: a three-case report. ( Drost, G; Erasmus, CE; Ginjaar, IB; Markhorst, JM; Sie, LT; Stunnenberg, BC, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Markhorst, JM | 1 |
| Stunnenberg, BC | 1 |
| Ginjaar, IB | 1 |
| Drost, G | 1 |
| Erasmus, CE | 1 |
| Sie, LT | 1 |
| Fujii, K | 1 |
| Iranami, H | 1 |
| Hatano, Y | 1 |
| Bissay, V | 1 |
| Keymolen, K | 1 |
| Lissens, W | 1 |
| Laureys, G | 1 |
| Schmedding, E | 1 |
| De Keyser, J | 1 |
| ALLSOP, JL | 1 |
| GOULSTON, K | 1 |
| JOHNSTON, C | 1 |
| KELLY, D | 1 |
| RAIL, L | 1 |
| CARSON, MJ | 1 |
| PEARSON, CM | 1 |
| Layzer, RB | 1 |
| Lovelace, RE | 1 |
| Rowland, LP | 2 |
| Fontaine, B | 1 |
| Griggs, RC | 2 |
| Moxley, RT | 1 |
| Riggs, JE | 1 |
| Engel, WK | 1 |
| Lisak, RP | 1 |
| Lebeau, J | 1 |
| Tucker, SH | 1 |
| Kusakabe, T | 1 |
| Shiotu, H | 1 |
| Nishikawa, M | 1 |
1 review available for acetazolamide and Myotonia
| Article | Year |
|---|---|
[Ion-channel related muscular diseases].
Topics: Acetazolamide; Anti-Arrhythmia Agents; Anticonvulsants; Carbamazepine; Humans; Hypokalemic Periodic | 1999 |
1 trial available for acetazolamide and Myotonia
| Article | Year |
|---|---|
Effect of acetazolamide on myotonia.
Topics: Acetazolamide; Adult; Child; Clinical Trials as Topic; Female; Humans; Male; Myotonia; Myotonia Cong | 1977 |
9 other studies available for acetazolamide and Myotonia
| Article | Year |
|---|---|
Clinical experience with long-term acetazolamide treatment in children with nondystrophic myotonias: a three-case report.
Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Child; Female; Humans; Male; Myotonia; Tre | 2014 |
Exacerbation of acetazolamide-responsive sodium channel myotonia by uterotonic agents.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cesarean Section; Drug Interactions; Female; Humans; M | 2011 |
Late onset painful cold-aggravated myotonia: three families with SCN4A L1436P mutation.
Topics: Acetazolamide; Adult; Age of Onset; Aged; Aged, 80 and over; Amitriptyline; Anticonvulsants; Belgium | 2011 |
FAMILIAL HYPERKALAEMIC PERIODIC PARALYSIS.
Topics: Acetazolamide; Adolescent; Blood Chemical Analysis; Calcium; Electrocardiography; Electromyography; | 1964 |
FAMILIAL HYPERKALEMIC PERIODIC PARALYSIS WITH MYOTONIC FEATURES.
Topics: 17-Ketosteroids; Acetazolamide; Adolescent; Biopsy; Blood Chemical Analysis; Child; Dextroamphetamin | 1964 |
Hyperkalemic periodic paralysis.
Topics: Acetazolamide; Adolescent; Adult; Aged; Child; Cold Temperature; Electromyography; Female; Glucose T | 1967 |
The myotonic disorders and the periodic paralyses.
Topics: Acetazolamide; Benzothiadiazines; Diuretics; Humans; Male; Muscle Contraction; Myotonia; Myotonia Co | 1977 |
Hyperkalemic periodic paralysis and cardiac arrhythmia.
Topics: Acetazolamide; Adolescent; Arrhythmias, Cardiac; Blood Glucose; Electrocardiography; Electromyograph | 1972 |
Metabolic studies on a case of paroxysmal myotonia with periodic paralysis.
Topics: Acetazolamide; Adult; Blood Glucose; Electrolytes; Electromyography; Humans; Hypokalemia; Insulin; M | 1974 |