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acetazolamide and Myasthenia Gravis

acetazolamide has been researched along with Myasthenia Gravis in 2 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Landau, K1
Carmignani, M1
Scoppetta, C1
Ranelletti, FO1
Tonali, P1

Reviews

1 review available for acetazolamide and Myasthenia Gravis

ArticleYear
[Neuro-ophthalmology essentials].
    Therapeutische Umschau. Revue therapeutique, 2009, Volume: 66, Issue:3

    Topics: Acetazolamide; Adrenal Cortex Hormones; Adult; Aged; Blepharoptosis; Carbonic Anhydrase Inhibitors;

2009

Other Studies

1 other study available for acetazolamide and Myasthenia Gravis

ArticleYear
Adverse interaction between acetazolamide and anticholinesterase drugs at the normal and myasthenic neuromuscular junction level.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:3

    Topics: Acetazolamide; Action Potentials; Adult; Animals; Cholinesterase Inhibitors; Female; Humans; In Vitr

1984