acetazolamide has been researched along with Muscle Contraction in 20 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (60.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dominelli, PB | 1 |
| McNeil, CJ | 1 |
| Vermeulen, TD | 1 |
| Stuckless, TJR | 1 |
| Brown, CV | 1 |
| Dominelli, GS | 1 |
| Swenson, ER | 1 |
| Teppema, LJ | 1 |
| Foster, GE | 1 |
| Wetzel, P | 3 |
| Kleinke, T | 1 |
| Papadopoulos, S | 2 |
| Gros, G | 3 |
| Tricarico, D | 1 |
| Mele, A | 1 |
| Conte Camerino, D | 1 |
| Kaneda, T | 1 |
| Sakaguchi, R | 1 |
| Shimizu, K | 1 |
| Urakawa, N | 1 |
| Nakajyo, S | 1 |
| Connett, RJ | 1 |
| Hays, ET | 1 |
| Gilda, EN | 1 |
| Torres, C | 1 |
| Moxley, RT | 1 |
| Griggs, RC | 2 |
| Carmignani, M | 1 |
| Ranelletti, FO | 1 |
| Marchetti, P | 1 |
| Ripanti, G | 1 |
| Oishi, M | 1 |
| Mochizuki, Y | 1 |
| Hara, M | 1 |
| Takasu, T | 1 |
| Scheid, P | 2 |
| Kuhlmann, WD | 1 |
| Fedde, MR | 1 |
| Frémont, P | 1 |
| Riverin, H | 1 |
| Frenette, J | 1 |
| Rogers, PA | 1 |
| Côté, C | 1 |
| Liebner, T | 1 |
| Nicholson, AN | 1 |
| Smith, PA | 1 |
| Stone, BM | 1 |
| Bradwell, AR | 1 |
| Coote, JH | 1 |
| Links, TP | 1 |
| Zwarts, MJ | 1 |
| Oosterhuis, HJ | 1 |
| Barclay, JK | 1 |
| Siffert, W | 1 |
| Lundberg, PO | 1 |
| Stålberg, E | 1 |
| Thiele, B | 1 |
| Zierler, KL | 1 |
| Paulo, LG | 1 |
| Sollero, L | 1 |
| Kurtz, GS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Carbonic Anhydrase Inhibitors on the Pulmonary System Response to Muscle Fatigue.[NCT02758470] | Phase 4 | 13 participants (Actual) | Interventional | 2016-11-30 | Completed | ||
| Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544] | 34 participants (Actual) | Interventional | 2012-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for acetazolamide and Muscle Contraction
| Article | Year |
|---|---|
Effect of acetazolamide and methazolamide on diaphragm and dorsiflexor fatigue: a randomized controlled trial.
Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Diaphragm; Electric Stimulation; Electromyograp | 2018 |
Altitude insomnia: studies during an expedition to the Himalayas.
Topics: Acetazolamide; Adult; Altitude Sickness; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Elec | 1988 |
Improvement of muscle strength in familial hypokalaemic periodic paralysis with acetazolamide.
Topics: Acetazolamide; Adult; Clinical Trials as Topic; Electromyography; Female; Humans; Male; Middle Aged; | 1988 |
17 other studies available for acetazolamide and Muscle Contraction
| Article | Year |
|---|---|
Inhibition of muscle carbonic anhydrase slows the Ca(2+) transient in rat skeletal muscle fibers.
Topics: Acetazolamide; Action Potentials; Adenosine Triphosphatases; Animals; Benzothiazoles; Calcium; Carbo | 2002 |
Phenotype-dependent functional and pharmacological properties of BK channels in skeletal muscle: effects of microgravity.
Topics: Acetazolamide; Action Potentials; Animals; Calcium; Carbonic Anhydrase Inhibitors; Cells, Cultured; | 2005 |
Effects of high-K+, Na+-deficient solution on contractility of the smooth muscles of the bovine trachea.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Animals; Bumetanide; Calcium; Cattl | 2006 |
Involvement of transport of H+ equivalents in activation-induced alkaline shift in frog muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Acid-Base Equilibrium; Am | 1984 |
Quantitative testing of handgrip strength, myotonia, and fatigue in myotonic dystrophy.
Topics: Acetazolamide; Adult; Aged; Electromyography; Female; Hand; Humans; Male; Middle Aged; Muscle Contra | 1983 |
Acetazolamide and smooth muscle: possible mechanisms conditioning the contractile responses induced by various experimental procedures in several isolated preparations.
Topics: Acetazolamide; Acetylcholine; Animals; Duodenum; Guinea Pigs; Ileum; In Vitro Techniques; Jejunum; M | 1981 |
Central motor conduction time in patients with periventricular lucencies.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cerebral Ventricles; Cerebral Ventriculography; Cerebr | 1996 |
Inhibition of muscle carbonic anhydrase increases rise and relaxation times of twitches in rat skeletal muscle fibres.
Topics: Acetazolamide; Animals; Benzolamide; Benzothiazoles; Bicarbonates; Buffers; Carbon Dioxide; Carbonic | 2002 |
Intrapulmonary receptors in the Tegu lizard: II. Functional characteristics and localization;.
Topics: Acetazolamide; Animals; Carbon Dioxide; Chemoreceptor Cells; Electric Stimulation; Electrophysiology | 1977 |
The myotonic disorders and the periodic paralyses.
Topics: Acetazolamide; Benzothiadiazines; Diuretics; Humans; Male; Muscle Contraction; Myotonia; Myotonia Co | 1977 |
Fatigue and recovery of rat soleus muscle are influenced by inhibition of an intracellular carbonic anhydrase isoform.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Female; Intracellular Membranes; Isoenzymes; | 1991 |
Carbonic anhydrase inhibition and calcium transients in soleus fibers.
Topics: Acetazolamide; Acidosis; Animals; Biological Transport; Calcium; Carbonic Anhydrase Inhibitors; Carb | 1990 |
Carbonic anhydrase III inhibition in normocapnic and hypercapnic contracting mouse soleus.
Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cyanates | 1987 |
Effects of inhibiting carbonic anhydrase on isometric contraction of frog skeletal muscle.
Topics: Acetazolamide; Action Potentials; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethox | 1985 |
Paralysis periodica paramyotonica. A clinical and neurophysiological study.
Topics: Acetazolamide; Acetylcholine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Calcium; Cre | 1974 |
Speculations on hypokalemic periodic paralysis.
Topics: Acetazolamide; Action Potentials; Cell Membrane Permeability; Electromyography; Humans; Hydrogen-Ion | 1973 |
Effects of sulfonamides on isolated preparations.
Topics: Acetazolamide; Acetylcholine; Animals; Anura; Chlorothiazide; Drug Synergism; Electric Stimulation; | 1972 |