acetazolamide has been researched along with Morphine Abuse in 1 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "When nalorphine (20mg/kg) was administered to rats previously treated with morphine three times daily for 2 weeks, there was an increase in brain glucose (100%), lactate (23%), pyruvate (18%) and citrate (10%) concentrations." | 1.25 | The effects of acute and chronic morphine treatment and of morphine withdrawal on rat brain in vivo. ( Harris, RL; Hawkins, RA; Miller, AL; Veech, RL, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, AL | 1 |
| Hawkins, RA | 1 |
| Harris, RL | 1 |
| Veech, RL | 1 |
1 other study available for acetazolamide and Morphine Abuse
| Article | Year |
|---|---|
The effects of acute and chronic morphine treatment and of morphine withdrawal on rat brain in vivo.
Topics: Acetazolamide; Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Animals; Arteries; Aspartic A | 1972 |