acetazolamide has been researched along with Malignant Melanoma in 4 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this work we have evaluated effects of umbelliferone and acetazolamide in a high resistant melanoma cell line (A375) over expressing CA IX." | 7.88 | Umbelliferone Decreases Intracellular pH and Sensitizes Melanoma Cell Line A375 to Dacarbazin. Comparison with Acetazolamide. ( Chatard, M; Felder-Flesch, D; Perek, N; Prevot, N; Puech, C, 2018) |
| "In this work we have evaluated effects of umbelliferone and acetazolamide in a high resistant melanoma cell line (A375) over expressing CA IX." | 3.88 | Umbelliferone Decreases Intracellular pH and Sensitizes Melanoma Cell Line A375 to Dacarbazin. Comparison with Acetazolamide. ( Chatard, M; Felder-Flesch, D; Perek, N; Prevot, N; Puech, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krasavin, M | 1 |
| Shetnev, A | 1 |
| Sharonova, T | 1 |
| Baykov, S | 1 |
| Kalinin, S | 1 |
| Nocentini, A | 1 |
| Sharoyko, V | 1 |
| Poli, G | 1 |
| Tuccinardi, T | 1 |
| Presnukhina, S | 1 |
| Tennikova, TB | 1 |
| Supuran, CT | 1 |
| Abbas, Q | 1 |
| Raza, H | 1 |
| Hassan, M | 1 |
| Phull, AR | 1 |
| Kim, SJ | 1 |
| Seo, SY | 1 |
| Puech, C | 1 |
| Chatard, M | 1 |
| Felder-Flesch, D | 1 |
| Prevot, N | 1 |
| Perek, N | 1 |
| Meyer, KM | 1 |
| Klink, T | 1 |
| Ugurel, S | 1 |
| Bröcker, EB | 1 |
4 other studies available for acetazolamide and Malignant Melanoma
| Article | Year |
|---|---|
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line; Cell Line, Tum | 2019 |
Acetazolamide Inhibits the Level of Tyrosinase and Melanin: An Enzyme Kinetic, In Vitro, In Vivo, and In Silico Studies.
Topics: Acetazolamide; Agaricales; Animals; Cell Line, Tumor; Cell Survival; Computer Simulation; Enzyme Inh | 2017 |
Umbelliferone Decreases Intracellular pH and Sensitizes Melanoma Cell Line A375 to Dacarbazin. Comparison with Acetazolamide.
Topics: Acetazolamide; Apoptosis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Cell Line, Tumor; Da | 2018 |
Regression of paclitaxel-induced maculopathy with oral acetazolamide.
Topics: Acetazolamide; Administration, Oral; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chem | 2012 |