acetazolamide has been researched along with Kidney Stones in 36 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of recurrent renal calculi containing calcium phosphate associated with long-term acetazolamide treatment for epilepsy." | 7.70 | Calcium phosphate stones during long-term acetazolamide treatment for epilepsy. ( Paisley, KE; Tomson, CR, 1999) |
| " Prevention of renal complications at the time of glaucoma treatment with acetazolamide." | 4.81 | [Therapeutic use of potassium citrate]. ( Dembińska, E; Klinger, M; Krajewska, M; Mazanowska, O; Puziewicz-Zmonarska, A; Zmonarski, SC, 2001) |
| "We report a case of a 33 years old female with a history of paroxystic hemidystonia treated by acetazolamide, a carbonic anhydrase inhibitor (CAI), and who developed two years after the initiation of this treatment bilateral radio-opaque stones." | 3.72 | [Carbonic anhydrase inhibitors and calcium phosphate stones]. ( Barbey, F; Burnier, M; Daudon, M; Ferrier, C; Nseir, G, 2004) |
| "We report a case of recurrent renal calculi containing calcium phosphate associated with long-term acetazolamide treatment for epilepsy." | 3.70 | Calcium phosphate stones during long-term acetazolamide treatment for epilepsy. ( Paisley, KE; Tomson, CR, 1999) |
| "Calcium metabolism and its response to citrate were examined in 51 patients with glaucoma receiving carbonic anhydrase inhibitors (acetazolamide or methazolamide)." | 3.68 | Calcium metabolism in acidotic patients induced by carbonic anhydrase inhibitors: responses to citrate. ( Araie, M; Aso, Y; Higashihara, E; Nutahara, K; Shoji, N; Takeuchi, T, 1991) |
| "Twelve patients who formed renal stones during acetazolamide treatment for glaucoma were studied." | 3.67 | Urine composition and stone formation during treatment with acetazolamide. ( Ahlstrand, C; Tiselius, HG, 1987) |
| " A daily dose of 10mg/kg of AZA was first administered and then the dosage was increased up to 20mg/kg based on the clinical response and side effects." | 2.70 | Long-term effectiveness and side effects of acetazolamide as an adjunct to other anticonvulsants in the treatment of refractory epilepsies. ( Katayama, F; Miura, H; Takanashi, S, 2002) |
| "Acetazolamide was effective in increasing the urinary pH in patients with uric acid and cystine stone formation who were already taking potassium citrate." | 1.35 | Acetazolamide is an effective adjunct for urinary alkalization in patients with uric acid and cystine stone formation recalcitrant to potassium citrate. ( Nakada, SY; Penniston, KL; Sterrett, SP; Wolf, JS, 2008) |
| "Carbonic anhydrase inhibitors can cause nephrolithiasis." | 1.29 | Acetazolamide-induced nephrolithiasis: implications for treatment of neuromuscular disorders. ( Griggs, RC; Moxley, RT; Tawil, R, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (66.67) | 18.7374 |
| 1990's | 7 (19.44) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Whittamore, JM | 1 |
| Hatch, M | 1 |
| Sterrett, SP | 1 |
| Penniston, KL | 1 |
| Wolf, JS | 1 |
| Nakada, SY | 1 |
| ABESHOUSE, BS | 2 |
| APPLEFELD, W | 2 |
| BARRAQUER, J | 1 |
| ESCRIBANO, J | 1 |
| GORDON, EE | 1 |
| SHEPS, SG | 1 |
| YATES-BELL, JG | 1 |
| DAVIES, DW | 1 |
| MACKENZIE, AR | 1 |
| Barbey, F | 1 |
| Nseir, G | 1 |
| Ferrier, C | 1 |
| Burnier, M | 1 |
| Daudon, M | 1 |
| Yazaki, T | 1 |
| Kaneko, S | 1 |
| Umeyama, T | 1 |
| Koiso, K | 1 |
| Donoso, LA | 1 |
| Eiferman, RA | 1 |
| Magargal, LE | 1 |
| Sutton, RA | 2 |
| Walker, VR | 1 |
| Tawil, R | 1 |
| Moxley, RT | 1 |
| Griggs, RC | 1 |
| Libenson, MH | 1 |
| Kaye, EM | 1 |
| Rosman, NP | 1 |
| Gilmore, HE | 1 |
| Paisley, KE | 1 |
| Tomson, CR | 1 |
| Zmonarski, SC | 1 |
| Klinger, M | 1 |
| Puziewicz-Zmonarska, A | 1 |
| Krajewska, M | 1 |
| Mazanowska, O | 1 |
| Dembińska, E | 1 |
| Katayama, F | 1 |
| Miura, H | 1 |
| Takanashi, S | 1 |
| Neto, M | 1 |
| Pilloff, B | 1 |
| Simon, J | 1 |
| Freed, SZ | 1 |
| Rubenstein, MA | 1 |
| Bucy, JG | 1 |
| Higashihara, E | 1 |
| Nutahara, K | 1 |
| Takeuchi, T | 1 |
| Shoji, N | 1 |
| Araie, M | 1 |
| Aso, Y | 1 |
| Wilson, DM | 1 |
| Resor, SR | 1 |
| Resor, LD | 1 |
| Hamm, LL | 1 |
| Rivalan, J | 1 |
| Chevet, D | 1 |
| Le Pogamp, P | 1 |
| Charasse, C | 1 |
| Joyeux, V | 1 |
| Bearn, PE | 1 |
| Itami, N | 1 |
| Kawaguti, M | 1 |
| Akutsu, Y | 1 |
| Mizutani, K | 1 |
| Tochimaru, H | 1 |
| Takekoshi, Y | 1 |
| Ahlstrand, C | 1 |
| Tiselius, HG | 1 |
| Røise, O | 1 |
| Otnes, B | 1 |
| Pepys, MB | 1 |
| Parfitt, AM | 2 |
| Kurz, M | 1 |
| Gofman, L | 1 |
| Sinkó, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study to Assess the Effects of Regulating Urine pH Levels for Alleviating Chronic Joint Pain[NCT01421160] | Phase 1 | 0 participants (Actual) | Interventional | 2011-07-31 | Withdrawn (stopped due to PI left the institution prior to any data being collected) | ||
| Non-inferiority Prospective Randomized Trial of Acetazolamide Versus Diazepam in Patients With Continuous Spike and Wave in Sleep (CSWS)/Landau Kleffner Syndrome (LKS)[NCT02904265] | Phase 2/Phase 3 | 3 participants (Actual) | Interventional | 2016-09-30 | Terminated (stopped due to Lack of enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Expect improved side effect profile of acetazolamide compared to diazepam at short-term follow up (NCT02904265)
Timeframe: 4-8 weeks of start of medications
| Intervention | Participants (Count of Participants) |
|---|---|
| Diazepam | 1 |
| Acetazolamide | 2 |
5 reviews available for acetazolamide and Kidney Stones
| Article | Year |
|---|---|
[Clinical application of diuretics: renal calculi].
Topics: Acetazolamide; Benzothiadiazines; Calcium; Diuretics; Humans; Kidney Calculi; Magnesium; Recurrence; | 1984 |
[Therapeutic use of potassium citrate].
Topics: Acetazolamide; Administration, Oral; Contraindications; Glaucoma; Humans; Hyperoxaluria; Kidney Calc | 2001 |
Clinical and laboratory evaluation of renal stone patients.
Topics: Acetazolamide; Humans; Kidney Calculi; Kidney Tubules; Recurrence; Risk Factors | 1990 |
Renal handling of citrate.
Topics: Acetazolamide; Acid-Base Equilibrium; Animals; Biological Transport, Active; Citrates; Citric Acid; | 1990 |
Diuretics and calcium metabolism.
Topics: Absorption; Acetazolamide; Adult; Animals; Benzothiadiazines; Calcium; Diuretics; Dogs; Furosemide; | 1985 |
2 trials available for acetazolamide and Kidney Stones
| Article | Year |
|---|---|
Acetazolamide and furosemide for posthemorrhagic hydrocephalus of the newborn.
Topics: Acetazolamide; Cerebral Hemorrhage; Cerebrospinal Fluid Shunts; Diuretics; Drainage; Drug Therapy, C | 1999 |
Long-term effectiveness and side effects of acetazolamide as an adjunct to other anticonvulsants in the treatment of refractory epilepsies.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epil | 2002 |
29 other studies available for acetazolamide and Kidney Stones
| Article | Year |
|---|---|
Oxalate transport by the mouse intestine in vitro is not affected by chronic challenges to systemic acid-base homeostasis.
Topics: Acetazolamide; Acidosis; Ammonium Chloride; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydra | 2019 |
Acetazolamide is an effective adjunct for urinary alkalization in patients with uric acid and cystine stone formation recalcitrant to potassium citrate.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cystine; Drug Therapy, | 2008 |
Citrate metabolism in urolithiasis: the role of acetazolamide (diamox) in the formation of calculi and calcium deposits in the kidney.
Topics: Acetazolamide; Calculi; Citrates; Citric Acid; Humans; Insurance, Health; Kidney; Kidney Calculi; Ur | 1956 |
Citrate metabolism in urolithiasis: the role of acetazolamide (diamox) in the formation of calculi and calcium deposits in the kidney.
Topics: Acetazolamide; Calculi; Citrates; Citric Acid; Humans; Insurance, Health; Kidney; Kidney Calculi; Ur | 1956 |
Citrate metabolism in urolithiasis: the role of acetazolamide (diamox) in the formation of calculi and calcium deposits in the kidney.
Topics: Acetazolamide; Calculi; Citrates; Citric Acid; Humans; Insurance, Health; Kidney; Kidney Calculi; Ur | 1956 |
Citrate metabolism in urolithiasis: the role of acetazolamide (diamox) in the formation of calculi and calcium deposits in the kidney.
Topics: Acetazolamide; Calculi; Citrates; Citric Acid; Humans; Insurance, Health; Kidney; Kidney Calculi; Ur | 1956 |
[Renal colic in the course of acetazolamide therapy].
Topics: Acetazolamide; Calculi; Humans; Kidney; Kidney Calculi; Renal Colic | 1957 |
Effect of acetazolamide on citrate excretion and formation of renal calculi.
Topics: Acetazolamide; Biological Transport; Body Fluids; Calculi; Citrates; Citric Acid; Humans; Kidney; Ki | 1957 |
Renal colic and anuria from acetazolamide.
Topics: Acetazolamide; Anuria; Calculi; Colic; Humans; Kidney; Kidney Calculi; Renal Colic | 1958 |
Acetazolamide therapy with renal complications.
Topics: Acetazolamide; Calculi; Humans; Kidney; Kidney Calculi | 1959 |
Acetazolamide-induced renal stone.
Topics: Acetazolamide; Humans; Kidney Calculi; Urinary Calculi | 1960 |
[Carbonic anhydrase inhibitors and calcium phosphate stones].
Topics: Acetazolamide; Adult; Calcium Phosphates; Carbonic Anhydrase Inhibitors; Dystonia; Female; Humans; K | 2004 |
Fuchs' heterochromic cyclitis associated with subclavian steal syndrome.
Topics: Acetazolamide; Adult; Cataract Extraction; Corneal Dystrophies, Hereditary; Fuchs' Endothelial Dystr | 1981 |
Responses to hydrochlorothiazide and acetazolamide in patients with calcium stones. Evidence suggesting a defect in renal tubular function.
Topics: Acetazolamide; Adult; Calcium; Creatinine; Electrolytes; Female; Humans; Hydrochlorothiazide; Kidney | 1980 |
Acetazolamide-induced nephrolithiasis: implications for treatment of neuromuscular disorders.
Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Humans; Kidney Calculi; Ma | 1993 |
Calcium phosphate stones during long-term acetazolamide treatment for epilepsy.
Topics: Acetazolamide; Adult; Anticonvulsants; Calcium Phosphates; Epilepsy; Humans; Kidney Calculi; Male; R | 1999 |
Dissolution of renal uric acid calculus with allopurinal and alkalization of urine: a case report.
Topics: Acetazolamide; Allopurinol; Bicarbonates; Citrates; Drug Combinations; Gout; Humans; Hydrogen-Ion Co | 1976 |
The alternating use of an alkalizing salt and acetazolamide in the management of cystine and uric acid stones.
Topics: Acetazolamide; Adolescent; Adult; Bicarbonates; Cystine; Cystinuria; Humans; Kidney Calculi; Kidney | 1975 |
Letter: Alkalinization of urine.
Topics: Acetazolamide; Bicarbonates; Glaucoma; Kidney Calculi; Urine | 1975 |
Acetazolamide-induced renal calculi.
Topics: Acetazolamide; Aged; Humans; Kidney Calculi; Male | 1975 |
Calcium metabolism in acidotic patients induced by carbonic anhydrase inhibitors: responses to citrate.
Topics: Acetazolamide; Acidosis; Calcium; Carbonic Anhydrase Inhibitors; Citrates; Citric Acid; Female; Glau | 1991 |
Chronic acetazolamide monotherapy in the treatment of juvenile myoclonic epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Child; Drug Evaluation; Epilepsies, Myoclonic; Fe | 1990 |
[Renal lithiasis, a logical complication of long-term treatment of glaucoma with a carbonic anhydrase inhibitor].
Topics: Acetazolamide; Female; Glaucoma; Humans; Kidney Calculi; Middle Aged | 1989 |
Disappearance of staghorn calculi following withdrawal of treatment with acetazolamide.
Topics: Acetazolamide; Glaucoma; Humans; Kidney Calculi; Middle Aged | 1989 |
Renal calcifications in preterm infants.
Topics: Acetazolamide; Furosemide; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Dis | 1989 |
Urine composition and stone formation during treatment with acetazolamide.
Topics: Acetazolamide; Adult; Aged; Calcium Oxalate; Calcium Phosphates; Female; Glaucoma; Humans; Hydrogen- | 1987 |
[Acetazolamide and renal calculi].
Topics: Acetazolamide; Aged; Female; Humans; Kidney Calculi; Male; Middle Aged; Risk | 1986 |
Acetazolamide and renal stone formation.
Topics: Acetazolamide; Adult; Glaucoma; Humans; Kidney Calculi; Male | 1970 |
Acetazolamide and renal stone formation.
Topics: Acetazolamide; Animals; Bicarbonates; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Rats | 1970 |
[Diamox and manifestation of diabetes mellitus].
Topics: Acetazolamide; Anuria; Blood Glucose; Carbonic Anhydrase Inhibitors; Diabetes Mellitus; Humans; Hype | 1968 |
Renal tubular acidosis in an adult.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adult; Age Factors; Carbonates; Carbonic Anhydrases; Citrate | 1969 |
Acetazolamide and sodium bicarbonate induced nephrocalcinosis and nephrolithiasis; relationship to citrate and calcium excretion.
Topics: Acetazolamide; Adult; Bicarbonates; Calcium; Carbonic Anhydrase Inhibitors; Citrates; Humans; Kidney | 1969 |