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acetazolamide and Kidney Failure, Chronic

acetazolamide has been researched along with Kidney Failure, Chronic in 30 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
" To investigate mechanisms of extrarenal buffering in uraemic acidosis, we studied the effects of the carbonic anhydrase inhibitor, acetazolamide, in normal subjects and in patients with end-stage kidney disease on maintenance haemodialysis with virtually no urine output."9.06Severe metabolic acidosis and disturbances of calcium metabolism induced by acetazolamide in patients on haemodialysis. ( Cecchin, E; De Marchi, S, 1990)
"Acetazolamide (Diamox) is a carbonic anhydrase inhibitor commonly used in patients with glaucoma in order to reduce intraocular pressure."7.69Acute hemorrhagic gastritis associated with acetazolamide intoxication in a patient with chronic renal failure. ( Kitamura, M; Matsuo, K; Nakamoto, M; Nishihara, G; Nozoe, T; Takeda, K; Urabe, M; Yasunaga, C, 1997)
"Acetazolamide was capable of preventing the excessive IOP rise during dialysis."5.28Intraocular pressure changes during hemodialysis: prevention of excessive dialytic rise and development of severe metabolic acidosis following acetazolamide therapy. ( Cecchin, E; De Marchi, S; Tesio, F, 1989)
" To investigate mechanisms of extrarenal buffering in uraemic acidosis, we studied the effects of the carbonic anhydrase inhibitor, acetazolamide, in normal subjects and in patients with end-stage kidney disease on maintenance haemodialysis with virtually no urine output."5.06Severe metabolic acidosis and disturbances of calcium metabolism induced by acetazolamide in patients on haemodialysis. ( Cecchin, E; De Marchi, S, 1990)
"Acetazolamide (Diamox) is a carbonic anhydrase inhibitor commonly used in patients with glaucoma in order to reduce intraocular pressure."3.69Acute hemorrhagic gastritis associated with acetazolamide intoxication in a patient with chronic renal failure. ( Kitamura, M; Matsuo, K; Nakamoto, M; Nishihara, G; Nozoe, T; Takeda, K; Urabe, M; Yasunaga, C, 1997)
"Acetazolamide is a weak diuretic used to decrease production of aqueous humor in the eye."1.28Acetazolamide in hemodialysis patients: a rational use after ocular surgery. ( Dufresne, LR; Legault, L; Long, H; Morin, C; Roy, LF, 1992)
"Pretreatment with acetazolamide was the most protective manoeuvre tested."1.28Long-term effects of acetazolamide and sodium chloride loading on cisplatin nephrotoxicity in the rat. ( Heidemann, HT; Hoffmann, K; Inselmann, G, 1990)
"Acetazolamide was capable of preventing the excessive IOP rise during dialysis."1.28Intraocular pressure changes during hemodialysis: prevention of excessive dialytic rise and development of severe metabolic acidosis following acetazolamide therapy. ( Cecchin, E; De Marchi, S; Tesio, F, 1989)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199019 (63.33)18.7374
1990's5 (16.67)18.2507
2000's3 (10.00)29.6817
2010's2 (6.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Pak, WLW1
Chan, KL1
Chan, Z1
Law, WP1
Wong, YH1
Lam, CK1
Wong, SHS1
Babiker, S1
Elsayed, ME1
Dhaygude, A1
Madgula, I1
Hour, BT1
Shah, AM1
Potharaju, AK1
Lien, YH1
Elinav, E1
Ackerman, Z1
Gottehrer, NP1
Heyman, SN1
ONEN, K1
SACKNER, MA1
WALLACK, AA1
BELLET, S1
Kagawa, S1
Fukumori, T1
Takahashi, A1
Kubota, T1
Shibahara, N1
Terasaki, J1
Kagitani, M1
Ueda, H1
Inoue, T1
Katsuoka, Y1
Angelopoulos, B1
Vlassopoulos, C1
Kalos, A1
Fossati, C1
Maisey, DN1
Brown, RD1
Goodfield, M1
Davis, J1
Jeffcoate, W1
Baekkevar, M1
Brørs, O1
Ostfeld, B1
Halevy, J1
Theodor, E1
Calvo, R1
Carlos, R1
Erill, S1
Takeda, K1
Nakamoto, M1
Yasunaga, C1
Nishihara, G1
Matsuo, K1
Urabe, M1
Kitamura, M1
Nozoe, T1
Schmidt, RW1
Breslau, NA1
Pak, CY1
Roy, LF1
Dufresne, LR1
Legault, L1
Long, H1
Morin, C1
Pham Hung, G1
Nahon, L1
Grimaud, D1
Heidemann, HT1
Hoffmann, K1
Inselmann, G1
De Marchi, S3
Cecchin, E3
Tesio, F1
Fillastre, JP2
Ardaillou, R2
Richet, G2
Schmidt, P1
Kleeman, CR1
Okun, R1
Heller, RJ1
Rieselbach, RE1
Gregory, DH1
Walker, FE1
Eichenholz, A1

Reviews

4 reviews available for acetazolamide and Kidney Failure, Chronic

ArticleYear
[Sleep apnea syndrome in dialysis patients].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 6

    Topics: Acetazolamide; Antidepressive Agents, Tricyclic; Continuous Positive Airway Pressure; Dialysis; Diet

2004
[Diuretics. II].
    La Clinica terapeutica, 1981, Nov-30, Volume: 99, Issue:4

    Topics: Acetazolamide; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antihypertensive Agents; Cardiac Glyc

1981
Hypoparathyroidism.
    Metabolism: clinical and experimental, 1979, Volume: 28, Issue:12

    Topics: Acetazolamide; Adenylyl Cyclases; Antacids; Bone and Bones; Calcium; Chlorthalidone; Dihydroxycholec

1979
[Management of metabolic alkalosis in the surgical patient].
    Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:2

    Topics: Acetazolamide; Alkalosis; Chlorides; Humans; Hydrochloric Acid; Kidney Failure, Chronic; Liver Disea

1991

Trials

2 trials available for acetazolamide and Kidney Failure, Chronic

ArticleYear
Severe metabolic acidosis and disturbances of calcium metabolism induced by acetazolamide in patients on haemodialysis.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:3

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Alkaline Phosphatase; Buffers; Calcitriol; Calcium;

1990
[Renal response to alkaline overload during chronic renal insufficiency].
    Journal d'urologie et de nephrologie, 1968, Volume: 74, Issue:9

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Renal Tubular; Bicarbonates; Clinical Trials as Topi

1968

Other Studies

24 other studies available for acetazolamide and Kidney Failure, Chronic

ArticleYear
Acetazolamide toxicity and dosing in dialysis patients.
    Nephrology (Carlton, Vic.), 2021, Volume: 26, Issue:1

    Topics: Acetazolamide; Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Humans; Kidney Failure, Chr

2021
A complex case of haemodialysis induced increased intraocular pressure.
    European journal of ophthalmology, 2019, Volume: 29, Issue:1_suppl

    Topics: Acetazolamide; Antihypertensive Agents; Diabetes Mellitus, Type 1; Glaucoma, Neovascular; Humans; In

2019
Quiz page January 2013: sudden deafness in a patient treated with long-term hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2013, Volume: 61, Issue:1

    Topics: Acetazolamide; Adult; Diabetic Nephropathies; Hearing Loss, Sudden; Humans; Hypercapnia; Intracrania

2013
Recurrent life-threatening acidosis induced by acetazolamide in a patient with diabetic type IV renal tubular acidosis.
    Annals of emergency medicine, 2002, Volume: 40, Issue:2

    Topics: Acetazolamide; Acidosis; Aged; Aged, 80 and over; Bicarbonates; Carbonic Anhydrase Inhibitors; Diabe

2002
[Effects of diamox on chronic nephropathies].
    Tip Fakultesi mecmuasi, 1958, Volume: 21, Issue:3

    Topics: Acetazolamide; Kidney Failure, Chronic; Kidney Function Tests; Renal Insufficiency, Chronic

1958
The diuretic effects of hydrochlorothiazide in congestive heart failure, cirrhosis, chronic renal disease and hypertension: preliminary report based on a study of 28 cases.
    The American journal of the medical sciences, 1959, Volume: 237, Issue:5

    Topics: Acetazolamide; Diuretics; Edema; Heart Failure; Hydrochlorothiazide; Hypertension; Kidney Failure, C

1959
The mechanism of hypoglycemia caused by hemodialysis.
    Clinical nephrology, 2004, Volume: 62, Issue:5

    Topics: Acetazolamide; Aged; Aged, 80 and over; Blood Glucose; Carbon Dioxide; Carbonic Anhydrase Inhibitors

2004
Experimental investigation and observations on the diuretic action of quinethazone.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14, Issue:6

    Topics: Acetazolamide; Adult; Chlorides; Chlorothiazide; Creatine; Diuresis; Drug Synergism; Edema; Female;

1966
Acetazolamide and symptomatic metabolic acidosis in mild renal failure.
    British medical journal (Clinical research ed.), 1981, Dec-05, Volume: 283, Issue:6305

    Topics: Acetazolamide; Acidosis, Renal Tubular; Aged; Female; Humans; Kidney Failure, Chronic; Male

1981
Acetazolamide and symptomatic metabolic acidosis in mild renal failure.
    British medical journal (Clinical research ed.), 1982, Feb-06, Volume: 284, Issue:6313

    Topics: Acetazolamide; Acidosis; Female; Humans; Kidney Failure, Chronic; Middle Aged

1982
[Acidosis with fatal outcome in a patient with renal insufficiency and glaucoma after treatment with acetazolamide].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1983, Feb-28, Volume: 103, Issue:6

    Topics: Acetazolamide; Acidosis; Aged; Female; Humans; Kidney Failure, Chronic

1983
[Acetazolamide-induced metabolic acidosis in elderly patients with mild renal failure].
    Harefuah, 1982, Volume: 103, Issue:1-2

    Topics: Acetazolamide; Acidosis; Aged; Female; Glaucoma; Humans; Kidney Failure, Chronic

1982
Effects of disease and acetazolamide on procaine hydrolysis by red blood cell enzymes.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:2

    Topics: Acetazolamide; Adult; Aged; Erythrocytes; Esterases; Female; Humans; Hydrolysis; In Vitro Techniques

1980
Acute hemorrhagic gastritis associated with acetazolamide intoxication in a patient with chronic renal failure.
    Clinical nephrology, 1997, Volume: 48, Issue:4

    Topics: Acetazolamide; Aged; Fatal Outcome; Female; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Gla

1997
Factors affecting HCO3 reabsorption in experimental renal insufficiency.
    The American journal of physiology, 1978, Volume: 234, Issue:6

    Topics: Acetazolamide; Acidosis; Ammonium Chloride; Animals; Bicarbonates; Carbonic Anhydrases; Dogs; Female

1978
Acetazolamide in hemodialysis patients: a rational use after ocular surgery.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 20, Issue:6

    Topics: Acetazolamide; Adult; Brain; Confusion; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; H

1992
Long-term effects of acetazolamide and sodium chloride loading on cisplatin nephrotoxicity in the rat.
    European journal of clinical investigation, 1990, Volume: 20, Issue:2

    Topics: Acetazolamide; Animals; Cisplatin; Creatinine; Kidney; Kidney Failure, Chronic; Male; Rats; Rats, In

1990
Intraocular pressure changes during hemodialysis: prevention of excessive dialytic rise and development of severe metabolic acidosis following acetazolamide therapy.
    Renal failure, 1989, Volume: 11, Issue:2-3

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Adult; Aged; Female; Gonioscopy; Humans; Intraocular

1989
More on the role of metabolic acidosis in causing uremic hyperphosphatemia.
    Mineral and electrolyte metabolism, 1987, Volume: 13, Issue:1

    Topics: Acetazolamide; Acidosis; Humans; Kidney Failure, Chronic; Phosphates; Renal Dialysis

1987
[Diuresis and diuretics].
    Wiener klinische Wochenschrift, 1971, Jun-25, Volume: 83, Issue:25

    Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder

1971
The renal regulation of sodium and potassium in patients with chronic renal failure (CRF) and the effect of diuretics on the excretion of these ions.
    Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2

    Topics: Acetazolamide; Adult; Diuretics; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Hu

1966
The new diuretics.
    Wisconsin medical journal, 1970, Volume: 69, Issue:7

    Topics: Acetazolamide; Chlorothiazide; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; Hypo

1970
[Bicarbonate excretion in response to an increased alkaline load in chronic renal insufficiency].
    Nephron, 1968, Volume: 5, Issue:6

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Adult; Bicarbonates; Blood Urea Nitrogen; Chlorides;

1968
Secondary proximal tubular acidosis.
    Metabolism: clinical and experimental, 1969, Volume: 18, Issue:3

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Renal Tubular; Adult; Aged; Bicarbonates; Blood Chem

1969