Page last updated: 2024-10-22

acetazolamide and Ischemia

acetazolamide has been researched along with Ischemia in 17 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the variations of preretinal oxygen partial pressure (Po(2)) in normal and in ischemic postexperimental branch retinal vein occlusion (BRVO) areas, during normoxia, hyperoxia (100% O(2)), and carbogen (95% O(2), 5% CO(2)) breathing before and after intravenous injection of acetazolamide."7.72Experimental retinal vein occlusion: effect of acetazolamide and carbogen (95% O2/5% CO2) on preretinal PO2. ( Munoz, JL; Petropoulos, IK; Pournaras, CJ; Pournaras, JA, 2004)
" Examination revealed significant facial edema, left proptosis, and a tight orbit, as well as no light perception and elevated intraocular pressure in the left eye, with complete internal and external ophthalmoplegia."3.73Ischemic orbital compartment syndrome as a complication of spinal surgery in the prone position. ( Casson, R; Laforest, C; Leibovitch, I; Selva, D, 2006)
"To evaluate the variations of preretinal oxygen partial pressure (Po(2)) in normal and in ischemic postexperimental branch retinal vein occlusion (BRVO) areas, during normoxia, hyperoxia (100% O(2)), and carbogen (95% O(2), 5% CO(2)) breathing before and after intravenous injection of acetazolamide."3.72Experimental retinal vein occlusion: effect of acetazolamide and carbogen (95% O2/5% CO2) on preretinal PO2. ( Munoz, JL; Petropoulos, IK; Pournaras, CJ; Pournaras, JA, 2004)
"The ischemia was induced by elevating intraocular pressure; retinal and RPE function were monitored by electrophysiologic recordings."1.28Recovery of retinal pigment epithelial function after ischemia in the rabbit. ( Heike, M; Marmor, MF, 1991)
"A large family with paroxysmal ataxia and continuous myokymic discharges is described."1.28Familial paroxysmal kinesigenic ataxia and continuous myokymia. ( Brunt, ER; van Weerden, TW, 1990)
"Pretreatment with acetazolamide produced a similar alkaline urine as the bicarbonate loading (pH 8."1.27Effect of sodium bicarbonate preloading on ischemic renal failure. ( Atkins, JL, 1986)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's4 (23.53)18.2507
2000's4 (23.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KAWASHIMA, K1
OOKA, R1
SAKANOUE, M1
KAWAI, T1
Pournaras, JA1
Petropoulos, IK1
Munoz, JL1
Pournaras, CJ1
Leibovitch, I1
Casson, R1
Laforest, C1
Selva, D1
Lee, AG1
Domoki, F1
Zimmermann, A1
Tóth-Szuki, V1
Busija, DW1
Bari, F1
Kraig, RP1
Ferreira-Filho, CR1
Nicholson, C1
Kerty, E3
Eide, N1
Hørven, I2
Heinze, JB1
Hueston, JT1
Heike, M1
Marmor, MF1
Brunt, ER1
van Weerden, TW1
Russell, D1
Bakke, SJ1
Nyberg-Hansen, R1
Rootwell, K1
Atkins, JL1
Hayreh, SS1
Richards, B1
Anderson, B1
Kontos, HA1
Mauck, HP1
Patterson, JL1

Other Studies

17 other studies available for acetazolamide and Ischemia

ArticleYear
E.R.G. on the acute ischemia by increasing ocular tension with the combination of the glucose metabolism alteration following administration of Diamox.
    The Keio journal of medicine, 1961, Volume: 10

    Topics: Acetazolamide; Electroretinography; Glaucoma; Glucose; Insulin; Intraocular Pressure; Ischemia; Reti

1961
Experimental retinal vein occlusion: effect of acetazolamide and carbogen (95% O2/5% CO2) on preretinal PO2.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:10

    Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Hyperoxia; Injections, Intrav

2004
Ischemic orbital compartment syndrome as a complication of spinal surgery in the prone position.
    Ophthalmology, 2006, Volume: 113, Issue:1

    Topics: Acetazolamide; Aged, 80 and over; Anesthesia, General; Compartment Syndromes; Drug Therapy, Combinat

2006
Orbital ischemia.
    Ophthalmology, 2006, Volume: 113, Issue:7

    Topics: Acetazolamide; Compartment Syndromes; Drug Therapy, Combination; Exophthalmos; Eye; Glucocorticoids;

2006
Acetazolamide induces indomethacin and ischaemia-sensitive pial arteriolar vasodilation in the piglet.
    Acta paediatrica (Oslo, Norway : 1992), 2008, Volume: 97, Issue:3

    Topics: Acetazolamide; Animals; Animals, Newborn; Arterioles; Carbonic Anhydrase Inhibitors; Cardiovascular

2008
Alkaline and acid transients in cerebellar microenvironment.
    Journal of neurophysiology, 1983, Volume: 49, Issue:3

    Topics: Acetazolamide; Acid-Base Equilibrium; Animals; Cerebellum; Cortical Spreading Depression; Evoked Pot

1983
Ocular hemodynamic changes in patients with high-grade carotid occlusive disease and development of chronic ocular ischaemia. II. Clinical findings.
    Acta ophthalmologica Scandinavica, 1995, Volume: 73, Issue:1

    Topics: Acetazolamide; Aged; Aged, 80 and over; Blindness; Blood Flow Velocity; Carotid Artery, Internal; Ca

1995
Ocular hemodynamic changes in patients with high-grade carotid occlusive disease and development of chronic ocular ischaemia. I. Doppler and dynamic tonometry findings.
    Acta ophthalmologica Scandinavica, 1995, Volume: 73, Issue:1

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Carotid Artery, Internal; Caroti

1995
Blindness after blepharoplasty: mechanism and early reversal.
    Plastic and reconstructive surgery, 1978, Volume: 61, Issue:3

    Topics: Acetazolamide; Adult; Blindness; Exophthalmos; Eyelids; Female; Hemorrhage; Humans; Intraocular Pres

1978
Recovery of retinal pigment epithelial function after ischemia in the rabbit.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:1

    Topics: Acetazolamide; Animals; Choroid; Dark Adaptation; Disease Models, Animal; Electroretinography; Intra

1991
Familial paroxysmal kinesigenic ataxia and continuous myokymia.
    Brain : a journal of neurology, 1990, Volume: 113 ( Pt 5)

    Topics: Acetazolamide; Adult; Ataxia; Carbonic Anhydrase Inhibitors; Child; Electrophysiology; Fasciculation

1990
Regional cerebral blood flow (rCBF) and cerebral vasoreactivity in patients with retinal ischaemic symptoms.
    Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:12

    Topics: Acetazolamide; Adult; Aged; Angiography; Arterial Occlusive Diseases; Arteriosclerosis; Blindness; C

1989
Effect of sodium bicarbonate preloading on ischemic renal failure.
    Nephron, 1986, Volume: 44, Issue:1

    Topics: Acetazolamide; Acute Kidney Injury; Animals; Bicarbonates; Creatinine; Diuresis; Hydrogen-Ion Concen

1986
Anterior ischaemic optic neuropathy. III. Treatment, prophylaxis, and differential diagnosis.
    The British journal of ophthalmology, 1974, Volume: 58, Issue:12

    Topics: Acetazolamide; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antihypertensive Agents; Arteri

1974
The relation between renal tissue ammonia concentration and ischemic renal damage.
    Investigative urology, 1971, Volume: 9, Issue:3

    Topics: Acetazolamide; Ammonia; Animals; Bicarbonates; Glutamates; Glutamine; Hydrochloric Acid; Ischemia; K

1971
Ocular effects of changes in oxygen and carbon dioxide tension.
    Transactions of the American Ophthalmological Society, 1968, Volume: 66

    Topics: Academic Dissertations as Topic; Acetazolamide; Adaptation, Ocular; Adult; Angiography; Atmospheric

1968
Mechanism of reactive hyperemia in limbs of anesthetized dogs.
    The American journal of physiology, 1965, Volume: 209, Issue:6

    Topics: Acetazolamide; Animals; Blood Gas Analysis; Carbon Dioxide; Dogs; Femoral Artery; Hyperemia; Ischemi

1965