acetazolamide has been researched along with Intellectual Disability in 14 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Interestingly, her episodes of ataxia were abolished by the administration of acetazolamide, similar to the response observed in episodic ataxia associated with other ion channels." | 1.42 | A Gain-of-Function Mutation in NALCN in a Child with Intellectual Disability, Ataxia, and Arthrogryposis. ( Aoyagi, K; Hamdan, FF; Michaud, JL; Mulcahy, B; Nagamatsu, S; Rossignol, E; Rouleau, GA; Xie, L; Zhen, M, 2015) |
| "Acetazolamide has been used since the 90's in neonates with progressive PHVD." | 1.32 | Retrospective analysis of post-hemorrhagic ventricular dilatation in very low birth weight infants, short and long-term outcome. ( Battajon, N; Chiandetti, L; Freato, F; Lago, P; Saia, OS; Zaramella, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoyagi, K | 1 |
| Rossignol, E | 1 |
| Hamdan, FF | 1 |
| Mulcahy, B | 1 |
| Xie, L | 1 |
| Nagamatsu, S | 1 |
| Rouleau, GA | 1 |
| Zhen, M | 1 |
| Michaud, JL | 1 |
| Gaffney, C | 1 |
| McNally, P | 1 |
| Koch, HJ | 1 |
| Sykora, A | 1 |
| Hausn, P | 1 |
| Verhulst, SL | 1 |
| De Dooy, J | 1 |
| Ramet, J | 1 |
| Bockaert, N | 1 |
| Van Coster, R | 1 |
| Ceulemans, B | 1 |
| De Backer, W | 1 |
| POIRE, R | 1 |
| ROYER, P | 1 |
| DEGRAEVE, M | 1 |
| RUSTIN, C | 1 |
| OLIVARES, L | 1 |
| MACGREGOR, M | 1 |
| Zaramella, P | 1 |
| Lago, P | 1 |
| Freato, F | 1 |
| Battajon, N | 1 |
| Saia, OS | 1 |
| Chiandetti, L | 1 |
| Feingold, M | 1 |
| Winsnes, A | 1 |
| Monn, E | 1 |
| Stokke, O | 1 |
| Feyling, T | 1 |
| Slusher, MM | 1 |
| Laibson, PR | 1 |
| Mulberger, RD | 1 |
| Di Cagno, L | 1 |
| Ravetto, A | 1 |
| Eeg-Olofsson, O | 1 |
| Claghorn, J | 1 |
| Neblett, C | 1 |
| Sutter, E | 1 |
| Farrell, G | 1 |
| Kraft, I | 1 |
1 trial available for acetazolamide and Intellectual Disability
| Article | Year |
|---|---|
The effect of drugs on hyperactivity in children with some observations of changes in mineral metabolism.
Topics: Acetazolamide; Adolescent; Amphetamine; Analysis of Variance; Child; Child, Preschool; Chlorides; Cl | 1971 |
13 other studies available for acetazolamide and Intellectual Disability
| Article | Year |
|---|---|
A Gain-of-Function Mutation in NALCN in a Child with Intellectual Disability, Ataxia, and Arthrogryposis.
Topics: Acetazolamide; Animals; Arthrogryposis; Ataxia; Caenorhabditis elegans; Caenorhabditis elegans Prote | 2015 |
Successful use of acetazolamide for central apnea in a child with Pitt-Hopkins syndrome.
Topics: Acetazolamide; Anticonvulsants; Facies; Humans; Hyperventilation; Intellectual Disability; Male; Pol | 2015 |
[Off-label use of acetazolamide in a patient with familial hemiplegic migraine and concomitant psychotic episodes].
Topics: Acetazolamide; Adult; Anticonvulsants; Carbonic Anhydrase Inhibitors; Comorbidity; Drug Costs; Drug | 2010 |
Acetazolamide for severe apnea in Pitt-Hopkins syndrome.
Topics: Acetazolamide; Apnea; Child; Facies; Humans; Hyperventilation; Intellectual Disability; Male; Young | 2012 |
[EXPERIMENTAL DETERMINATION OF ANTICONVULSANT PROPERTIES OF DICHLORPHENAMIDE BY ELECTROENCEPHALOGRAPHIC STUDY UNDER INTERMITTENT PHOTIC STIMULATION].
Topics: Acetazolamide; Adolescent; Alcoholism; Anticonvulsants; Anxiety; Bemegride; Dichlorphenamide; Electr | 1963 |
MORO REFLEX AND MYOCLONIC EPILEPSY. REPORT OF A CASE SEEMINGLY INDICATING A COMMON MECHANISM FOR BOTH.
Topics: Acetazolamide; Anticonvulsants; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Humans; Inf | 1963 |
EPILEPSY IN CHILDHOOD: CLASSIFICATION AND TREATMENT.
Topics: Acetazolamide; Adrenal Cortex Hormones; Angiomatosis; Barbiturates; Child; Classification; Electroen | 1964 |
Retrospective analysis of post-hemorrhagic ventricular dilatation in very low birth weight infants, short and long-term outcome.
Topics: Acetazolamide; Age Factors; Anticonvulsants; Cerebral Hemorrhage; Cerebral Ventricles; Child Develop | 2004 |
Unclassifiable birth defects--an approach.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Alkaline Phosphatase; Child, Preschool; Congenital Abnor | 1983 |
Congenital persistent proximal type renal tubular acidosis in two brothers.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Renal Tubular; Bicarbonates; Child; Dental Enamel; E | 1979 |
Aucte keratoconus in Down's syndrome.
Topics: Acetazolamide; Acute Disease; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Corneal Opacity | 1968 |
[Remote sequels of hypsarhythmic encephalopathy].
Topics: Acetazolamide; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Barbiturates; Brain Diseases; C | 1966 |
Experiences with Bivotril in treatment of epilepsy--particularly minor motor epilepsy--in mentally retarded children.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Child; Child, Preschool; Chlor | 1973 |