acetazolamide has been researched along with Innate Inflammatory Response in 14 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a prospective study, 41 patients with documented chronic macular edema of various causes were entered into a therapeutic trial of acetazolamide sodium, a carbonic anhydrase inhibitor." | 7.67 | Treatment of chronic macular edema with acetazolamide. ( Bird, AC; Cox, SN; Hay, E, 1988) |
| "Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects." | 5.51 | Would acetazolamide inhibit progression of atheromatous vascular calcification? ( Cochran, M, 2019) |
| "Temozolomide (TMZ) is used for treating glioblastoma." | 5.35 | Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008) |
| "In a prospective study, 41 patients with documented chronic macular edema of various causes were entered into a therapeutic trial of acetazolamide sodium, a carbonic anhydrase inhibitor." | 3.67 | Treatment of chronic macular edema with acetazolamide. ( Bird, AC; Cox, SN; Hay, E, 1988) |
| "Cardiac inflammation is generally accompanied by hypoxia, while myocardial injury and an abnormal microenvironment caused by hypoxia tend to suppress the efficacy of common anti-inflammatory drugs." | 1.72 | Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia. ( Gou, S; Liu, Z; Wang, C; Zhou, W, 2022) |
| "Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects." | 1.51 | Would acetazolamide inhibit progression of atheromatous vascular calcification? ( Cochran, M, 2019) |
| "Posthemorrhagic hydrocephalus (PHH), an expansion of the cerebral ventricles due to CSF accumulation following intraventricular hemorrhage (IVH), is a common disease usually treated by suboptimal CSF shunting techniques." | 1.46 | Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus. ( Alper, SL; Delpire, E; DiLuna, ML; Duran, D; Furey, CG; Gerzanich, V; Gunel, M; Kahle, KT; Karimy, JK; Kurland, DB; Mansuri, MS; Medzhitov, R; Montejo, J; Simard, JM; Stokum, JA; Theriault, BC; Vera, A; Zhang, J; Zhou, X, 2017) |
| "Inflammation was induced in one hind paw of rats by intraplantar injection of carrageenan (250 μg)." | 1.36 | Is the sulphonamide radical in the celecoxib molecule essential for its analgesic activity? ( Bakhle, YS; de Francischi, JN; dos Reis, WG; Ferreira-Alves, DL; Gassani, BC; Paiva-Lima, P; Rezende, RM, 2010) |
| "Temozolomide (TMZ) is used for treating glioblastoma." | 1.35 | Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Zhou, W | 1 |
| Wang, C | 1 |
| Liu, Z | 1 |
| Gou, S | 1 |
| Hu, Y | 1 |
| Sun, J | 1 |
| Wang, T | 1 |
| Wang, H | 1 |
| Zhao, C | 1 |
| Wang, W | 1 |
| Yan, K | 1 |
| Yan, X | 1 |
| Sun, H | 1 |
| Cochran, M | 1 |
| Horowitz, RI | 1 |
| Freeman, PR | 1 |
| Karimy, JK | 1 |
| Zhang, J | 1 |
| Kurland, DB | 1 |
| Theriault, BC | 1 |
| Duran, D | 1 |
| Stokum, JA | 1 |
| Furey, CG | 1 |
| Zhou, X | 1 |
| Mansuri, MS | 1 |
| Montejo, J | 1 |
| Vera, A | 1 |
| DiLuna, ML | 1 |
| Delpire, E | 1 |
| Alper, SL | 1 |
| Gunel, M | 1 |
| Gerzanich, V | 1 |
| Medzhitov, R | 1 |
| Simard, JM | 1 |
| Kahle, KT | 1 |
| Sun, A | 1 |
| Tang, X | 1 |
| Nie, D | 1 |
| Fan, Y | 1 |
| Tang, G | 1 |
| Gassani, BC | 1 |
| Rezende, RM | 1 |
| Paiva-Lima, P | 1 |
| Ferreira-Alves, DL | 1 |
| dos Reis, WG | 1 |
| Bakhle, YS | 1 |
| de Francischi, JN | 1 |
| Julian, CG | 1 |
| Subudhi, AW | 1 |
| Wilson, MJ | 1 |
| Dimmen, AC | 1 |
| Pecha, T | 1 |
| Roach, RC | 1 |
| Das, A | 1 |
| Banik, NL | 1 |
| Ray, SK | 1 |
| de Sèze, M | 1 |
| Krassinine, G | 1 |
| Montero, Cl | 1 |
| Teyssot, Cl | 1 |
| Sawa, M | 1 |
| Chumbley, LC | 1 |
| Morgan, AM | 1 |
| Musallam, I | 1 |
| Cox, SN | 1 |
| Hay, E | 1 |
| Bird, AC | 1 |
1 review available for acetazolamide and Innate Inflammatory Response
| Article | Year |
|---|---|
Compound Danshen Dripping Pill inhibits high altitude-induced hypoxic damage by suppressing oxidative stress and inflammatory responses.
Topics: Acetazolamide; Altitude Sickness; Animals; Blood Gas Analysis; Camphanes; Cytokines; Dose-Response R | 2021 |
1 trial available for acetazolamide and Innate Inflammatory Response
| Article | Year |
|---|---|
Acute mountain sickness, inflammation, and permeability: new insights from a blood biomarker study.
Topics: Acetazolamide; Acute Disease; Adult; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Biomarke | 2011 |
12 other studies available for acetazolamide and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Ca | 2022 |
Would acetazolamide inhibit progression of atheromatous vascular calcification?
Topics: Acetazolamide; Acidosis; Aged; Alkaline Phosphatase; Calcium; Disease Progression; Humans; Hydrogen- | 2019 |
Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials.
Topics: Acetazolamide; Anti-Inflammatory Agents; Anticoagulants; Clinical Laboratory Techniques; Coronavirus | 2020 |
Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus.
Topics: Acetazolamide; Animals; Antioxidants; Blotting, Western; Bumetanide; Cerebral Hemorrhage; Cerebral V | 2017 |
Positron Emission Tomography Imaging of Lesions pH Using
Topics: Acetazolamide; Animals; Bicarbonates; Carbon Radioisotopes; Carbonic Anhydrase Inhibitors; Cell Line | 2018 |
Is the sulphonamide radical in the celecoxib molecule essential for its analgesic activity?
Topics: Acetazolamide; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationsh | 2010 |
Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells.
Topics: Acetazolamide; Apoptosis; Aquaporin 1; Brain Edema; Brain Neoplasms; Calpain; Carbonic Anhydrases; C | 2008 |
[Account of clinical experiments using a salve formulation of acetazolamide].
Topics: Acetazolamide; Adult; Aged; Dosage Forms; Drug Evaluation; Edema; Female; Humans; Inflammation; Male | 1977 |
Clinical application of laser flare-cell meter.
Topics: Acetazolamide; Adult; Age Factors; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous H | 1990 |
Hydroxypropyl methylcellulose in extracapsular cataract surgery with intraocular lens implantation: intraocular pressure and inflammatory response.
Topics: Acetazolamide; Anterior Chamber; Ascorbic Acid; Cataract Extraction; Female; Humans; Hypromellose De | 1990 |
Treatment of chronic macular edema with acetazolamide.
Topics: Acetazolamide; Chronic Disease; Dose-Response Relationship, Drug; Eye Diseases; Fluorescein Angiogra | 1988 |