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acetazolamide and Infarction, Middle Cerebral Artery

acetazolamide has been researched along with Infarction, Middle Cerebral Artery in 14 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
" The present study was aimed at testing the hypothesis that regional cerebrovascular reactivity (rCVR) to acetazolamide can be a reliable predictor of subsequent ischemic stroke in medically treated patients with internal carotid artery or middle cerebral artery occlusion."5.09Long-term prognosis of medically treated patients with internal carotid or middle cerebral artery occlusion: can acetazolamide test predict it? ( Abe, H; Houkin, K; Iwasaki, Y; Kamiyama, H; Kuroda, S; Mitsumori, K, 2001)
" antiplatelet therapy), indicating a repeat TIA or ischemic stroke attack was noted during maximal medical therapy; having poor cerebral perfusion on CT imaging; and having regional cerebrovascular reactivity (rCVR) of <20% when acetazolamide challenge was undergone."3.78Extracranial-intracranial (EC-IC) bypass of symptomatic middle cerebral artery (MCA) total occlusion for haemodynamic impairment patients. ( Chang, JH; Chen, CC; Cheng, YW; Cho, DY; Chou, CW; Lin, SZ, 2012)
"Cumulative recurrence-free survival rates in all patients, and in each subgroup of patients with ICA or MCA occlusion and reduced rCVR on entry, were significantly lower than in those with normal rCVR (P=0."2.70Cerebrovascular reactivity to acetazolamide and outcome in patients with symptomatic internal carotid or middle cerebral artery occlusion: a xenon-133 single-photon emission computed tomography study. ( Ogasawara, K; Ogawa, A; Yoshimoto, T, 2002)
"Moyamoya disease is characterized by bilateral progressive terminal internal carotid arteries steno-occlusion."1.46Brain Perfusion Before and After Surgical Treatment of Moyamoya Disease. ( Boulahdour, H; Drouet, C; Morel, O; Porot, C; Thines, L, 2017)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (57.14)29.6817
2010's4 (28.57)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Roder, C1
Haas, P1
Fudali, M1
Milian, M1
Ernemann, U1
Meyer, PT1
Tatagiba, M1
Khan, N1
Han, M1
Kwon, I1
Ha, J1
Kim, J1
Cha, MJ1
Kim, YD1
Heo, JH1
Nam, HS1
Haga, S1
Morioka, T1
Shimogawa, T1
Akiyama, T1
Murao, K1
Kanazawa, Y1
Sayama, T1
Arakawa, S1
Bahr-Hosseini, M1
Shakur, SF1
Amin-Hanjani, S1
Charbel, FT1
Alaraj, A1
Drouet, C1
Morel, O1
Thines, L1
Porot, C1
Boulahdour, H1
Chou, CW1
Chang, JH1
Lin, SZ1
Cho, DY1
Cheng, YW1
Chen, CC1
Yamauchi, H1
Okazawa, H1
Kishibe, Y1
Sugimoto, K1
Takahashi, M1
Hori, A1
Harada, M1
Nishitani, H1
Uno, M1
Yamamoto, S1
Watanabe, M1
Uematsu, T1
Takasawa, K1
Nukata, M1
Kinoshita, N1
Ogasawara, K2
Tomitsuka, N1
Kobayashi, M1
Komoribayashi, N1
Fukuda, T1
Saitoh, H1
Inoue, T1
Ogawa, A2
Kimura, Y1
Oku, N1
Kajimoto, K1
Katoh, H1
Tanaka, MR1
Takasawa, M1
Imaizumi, M1
Kitagawa, K1
Hori, M1
Hatazawa, J1
Chen, A1
Shyr, MH1
Chen, TY1
Lai, HY1
Lin, CC1
Yen, PS1
Kuroda, S1
Houkin, K1
Kamiyama, H1
Mitsumori, K1
Iwasaki, Y1
Abe, H1
Yoshimoto, T1

Trials

3 trials available for acetazolamide and Infarction, Middle Cerebral Artery

ArticleYear
Reduced blood flow response to acetazolamide reflects pre-existing vasodilation and decreased oxygen metabolism in major cerebral arterial occlusive disease.
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:10

    Topics: Acetazolamide; Arterial Occlusive Diseases; Blood Flow Velocity; Brain; Carotid Artery Thrombosis; C

2002
Long-term prognosis of medically treated patients with internal carotid or middle cerebral artery occlusion: can acetazolamide test predict it?
    Stroke, 2001, Volume: 32, Issue:9

    Topics: Acetazolamide; Aged; Blood Flow Velocity; Brain; Carbonic Anhydrase Inhibitors; Carotid Stenosis; Ce

2001
Cerebrovascular reactivity to acetazolamide and outcome in patients with symptomatic internal carotid or middle cerebral artery occlusion: a xenon-133 single-photon emission computed tomography study.
    Stroke, 2002, Volume: 33, Issue:7

    Topics: Acetazolamide; Adult; Aged; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carotid Stenosis; Ce

2002

Other Studies

11 other studies available for acetazolamide and Infarction, Middle Cerebral Artery

ArticleYear
Neuropsychological impairment in adults with moyamoya angiopathy: preoperative assessment and correlation to MRI and H
    Neurosurgical review, 2020, Volume: 43, Issue:6

    Topics: Acetazolamide; Adolescent; Adult; Aged; Cerebrovascular Circulation; Cognition Disorders; Cohort Stu

2020
Collateral augmentation treatment with a combination of acetazolamide and head-down tilt in a rat ischemic stroke model.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 73

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Head-Down Tilt; Infarction,

2020
Arterial Spin Labeling Perfusion Magnetic Resonance Image with Dual Postlabeling Delay: A Correlative Study with Acetazolamide Loading (123)I-Iodoamphetamine Single-Photon Emission Computed Tomography.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:1

    Topics: Acetazolamide; Aged; Aged, 80 and over; Carotid Artery, Internal; Carotid Stenosis; Cerebral Arterie

2016
Angiographic Correlates of Cerebral Hemodynamic Changes With Diamox Challenge Assessed by Quantitative Magnetic Resonance Angiography.
    Stroke, 2016, Volume: 47, Issue:6

    Topics: Acetazolamide; Aged; Biomarkers; Carbonic Anhydrase Inhibitors; Carotid Artery Diseases; Cerebrovasc

2016
Brain Perfusion Before and After Surgical Treatment of Moyamoya Disease.
    Clinical nuclear medicine, 2017, Volume: 42, Issue:5

    Topics: Acetazolamide; Brain; Cerebrovascular Circulation; Humans; Infarction, Middle Cerebral Artery; Moyam

2017
Extracranial-intracranial (EC-IC) bypass of symptomatic middle cerebral artery (MCA) total occlusion for haemodynamic impairment patients.
    British journal of neurosurgery, 2012, Volume: 26, Issue:6

    Topics: Acetazolamide; Adult; Aged; Female; Hemodynamics; Humans; Infarction, Middle Cerebral Artery; Intrac

2012
Evaluation of cerebral blood flow reserve in patients with cerebrovascular disease by SPECT using technetium-99m-L, L-ethyl cysteinate dimer.
    The journal of medical investigation : JMI, 2002, Volume: 49, Issue:3-4

    Topics: Acetazolamide; Adult; Aged; Carotid Stenosis; Cerebrovascular Circulation; Cysteine; Female; Humans;

2002
Correlation of angiographic circulation time and cerebrovascular reserve by acetazolamide-challenged single photon emission CT.
    AJNR. American journal of neuroradiology, 2004, Volume: 25, Issue:2

    Topics: Acetazolamide; Aged; Aged, 80 and over; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carotid

2004
Stevens-Johnson syndrome associated with intravenous acetazolamide administration for evaluation of cerebrovascular reactivity. Case report.
    Neurologia medico-chirurgica, 2006, Volume: 46, Issue:3

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Humans; Infarction, Middl

2006
Diastolic blood pressure influences cerebrovascular reactivity measured by means of 123I-iodoamphetamine brain single photon emission computed tomography in medically treated patients with occlusive carotid or middle cerebral artery disease.
    Annals of nuclear medicine, 2006, Volume: 20, Issue:3

    Topics: Acetazolamide; Aged; Arterial Occlusive Diseases; Blood Pressure; Brain; Carotid Artery Diseases; Ce

2006
Dynamic CT perfusion imaging with acetazolamide challenge for evaluation of patients with unilateral cerebrovascular steno-occlusive disease.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:9

    Topics: Acetazolamide; Aged; Aged, 80 and over; Basal Ganglia; Blood Circulation; Blood Flow Velocity; Blood

2006