acetazolamide has been researched along with Hyperventilation in 28 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the protective effect of acetazolamide, a diuretic without significant effect on the loop cotransporter, with the protection provided by inhaled furosemide in a cold, dry air hyperventilation model of asthma." | 9.07 | Acetazolamide and furosemide attenuate asthma induced by hyperventilation of cold, dry air. ( Drazen, JM; Israel, E; Niven, RW; O'Donnell, WJ; Rosenberg, M, 1992) |
| "Acetazolamide pretreatment did not alter these IOP responses to PCO2, PO2, and blood pH changes." | 5.26 | Effect of hypercapnea and hyperventilation on human intraocular pressure general anaesthesia following acetazolamide administration. ( Chondreli, S; Petounis, AD; Vadaluka-Sekioti, A, 1980) |
| " We compared the protective effect of acetazolamide, a diuretic without significant effect on the loop cotransporter, with the protection provided by inhaled furosemide in a cold, dry air hyperventilation model of asthma." | 5.07 | Acetazolamide and furosemide attenuate asthma induced by hyperventilation of cold, dry air. ( Drazen, JM; Israel, E; Niven, RW; O'Donnell, WJ; Rosenberg, M, 1992) |
| "10 at each work load); 2) hyperventilation following acetazolamide (which returned pH to control values despite ventilation and PaCO2 identical to condition 1); and 3) metabolic acidosis induced by acetazolamide (with spontaneous ventilation)." | 5.06 | Effect of respiratory alkalosis during exercise on blood lactate. ( Davies, SF; Iber, C; Keene, SA; McArthur, CD; Path, MJ, 1986) |
| "Three normal volunteers and 12 patients with an obstruction of major cerebral arteries underwent PET measurements of the CBF after an injection of H2(15)O: (1) in the resting condition, (2) during hyperventilation (HV scan), (3) 1 to 3 minutes after hyperventilation (post-HV scan), (4) during the inhalation of 5% CO2, and (5) after an injection of acetazolamide." | 3.70 | Posthyperventilatory steal response in chronic cerebral hemodynamic stress: a positron emission tomography study. ( Hirakawa, K; Ishii, K; Matsushima, Y; Nariai, T; Senda, M; Toyama, H; Wakabayashi, S; Yokota, T, 1998) |
| "To elucidate the relationship between cerebral blood flow (CBF) after hyperventilation (HV) and the rebuild-up phenomenon on the encephaloelectrogram (EEG) in children with moyamoya disease, comparative study of CBF immediately after HV and CBF after administration of acetazolamide (Diamox) was examined." | 3.68 | [Cerebral blood flow reactivity to hyperventilation in children with spontaneous occlusion of the circle of willis (moyamoya disease)]. ( Abe, H; Isobe, M; Kamiyama, H; Kuroda, S; Mitumori, K, 1992) |
| " Incremental exercise to 175 W was performed on a bicycle ergometer under four conditions: 1) control, 2) during forced hyperventilation (HV), 3) after pretreatment with acetazolamide (AZE), and 4) while breathing 4% CO2." | 3.68 | Influence of acid-base status on plasma catecholamines during exercise in normal humans. ( Davies, SF; Goldsmith, SR; Iber, C; McArthur, CD, 1990) |
| "Limb shaking in Moyamoya disease may result from a transient hypoperfusion of the contralateral frontoparietal cortex rather than basal ganglia." | 1.32 | Hyperventilation-induced limb shaking TIA in Moyamoya disease. ( Chung, CS; Han, DH; Kim, HY; Lee, J; Lee, KH, 2003) |
| "Acetazolamide (1 g) was tested in 15 volunteers (age, 28+/-8 years)." | 1.30 | Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity. ( Bähr, RR; Buss, E; Eicke, BM; Hajak, G; Paulus, W, 1999) |
| "Acetazolamide pretreatment did not alter these IOP responses to PCO2, PO2, and blood pH changes." | 1.26 | Effect of hypercapnea and hyperventilation on human intraocular pressure general anaesthesia following acetazolamide administration. ( Chondreli, S; Petounis, AD; Vadaluka-Sekioti, A, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (60.71) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaffney, C | 1 |
| McNally, P | 1 |
| Verhulst, SL | 1 |
| De Dooy, J | 1 |
| Ramet, J | 1 |
| Bockaert, N | 1 |
| Van Coster, R | 1 |
| Ceulemans, B | 1 |
| De Backer, W | 1 |
| Kim, HY | 1 |
| Chung, CS | 1 |
| Lee, J | 1 |
| Han, DH | 1 |
| Lee, KH | 1 |
| HIRSCHOWITZ, BI | 1 |
| LONDON, JA | 1 |
| WIGGINS, HS | 1 |
| STROMME, JH | 1 |
| FOG, J | 1 |
| RAWLS, JA | 1 |
| WISTRAND, PJ | 1 |
| MAREN, TH | 1 |
| KRNJEVIC, K | 1 |
| RANDIC, M | 1 |
| SIESJOE, BK | 1 |
| Petounis, AD | 1 |
| Chondreli, S | 1 |
| Vadaluka-Sekioti, A | 1 |
| Stoll, M | 1 |
| Seidel, A | 1 |
| Treib, J | 1 |
| Hamann, GF | 1 |
| Nariai, T | 1 |
| Senda, M | 1 |
| Ishii, K | 1 |
| Wakabayashi, S | 1 |
| Yokota, T | 1 |
| Toyama, H | 1 |
| Matsushima, Y | 1 |
| Hirakawa, K | 1 |
| Eicke, BM | 1 |
| Buss, E | 1 |
| Bähr, RR | 1 |
| Hajak, G | 1 |
| Paulus, W | 1 |
| Venkatesha, SL | 1 |
| Umamaheswara Rao, GS | 1 |
| Olzowy, M | 1 |
| O'Donnell, WJ | 1 |
| Rosenberg, M | 1 |
| Niven, RW | 1 |
| Drazen, JM | 1 |
| Israel, E | 1 |
| Isobe, M | 1 |
| Kuroda, S | 1 |
| Kamiyama, H | 1 |
| Abe, H | 1 |
| Mitumori, K | 1 |
| Browne, TR | 1 |
| Feldman, RG | 1 |
| Mikati, MA | 1 |
| Burdette, D | 1 |
| Otis, J | 1 |
| Goldsmith, SR | 1 |
| Iber, C | 2 |
| McArthur, CD | 2 |
| Davies, SF | 2 |
| Teppema, LJ | 1 |
| Rochette, F | 1 |
| Demedts, M | 1 |
| Keene, SA | 1 |
| Path, MJ | 1 |
| Zborowska-Sluis, DT | 1 |
| Tozzi, DP | 1 |
| Klassen, GA | 1 |
| Forwand, SA | 1 |
| Landowne, M | 1 |
| Follansbee, JN | 1 |
| Hansen, JE | 1 |
| Sisson, WB | 1 |
| Andersen, HT | 1 |
| Hustvedt, BE | 1 |
| Stovner, J | 1 |
| Regli, F | 1 |
| Yamaguchi, T | 1 |
| Waltz, AG | 1 |
| Travis, DM | 1 |
| Marx, HH | 1 |
| Ames, A | 1 |
| Higashi, K | 1 |
| Nesbett, FB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544] | 34 participants (Actual) | Interventional | 2012-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetazolamide and Hyperventilation
| Article | Year |
|---|---|
Physiology of the choroid plexus and experimental studies of the cerebrospinal fluid: a review.
Topics: Acetazolamide; Animals; Biological Transport, Active; Blood Proteins; Cerebrospinal Fluid; Cerebrosp | 1969 |
4 trials available for acetazolamide and Hyperventilation
| Article | Year |
|---|---|
[Prevention of altitude sickness].
Topics: Acclimatization; Acetazolamide; Adult; Alkalosis, Respiratory; Altitude Sickness; Blood Pressure; Ca | 1975 |
Acetazolamide and furosemide attenuate asthma induced by hyperventilation of cold, dry air.
Topics: Acetazolamide; Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cold | 1992 |
Effect of respiratory alkalosis during exercise on blood lactate.
Topics: Acetazolamide; Acidosis; Adult; Alkalosis, Respiratory; Biofeedback, Psychology; Female; Humans; Hyd | 1986 |
Effect of acetazolamide on acute mountain sickness.
Topics: Acetazolamide; Acute Disease; Adult; Alkalosis; Altitude; Bicarbonates; Blood; Blood Pressure; Carbo | 1968 |
23 other studies available for acetazolamide and Hyperventilation
| Article | Year |
|---|---|
Successful use of acetazolamide for central apnea in a child with Pitt-Hopkins syndrome.
Topics: Acetazolamide; Anticonvulsants; Facies; Humans; Hyperventilation; Intellectual Disability; Male; Pol | 2015 |
Acetazolamide for severe apnea in Pitt-Hopkins syndrome.
Topics: Acetazolamide; Apnea; Child; Facies; Humans; Hyperventilation; Intellectual Disability; Male; Young | 2012 |
Hyperventilation-induced limb shaking TIA in Moyamoya disease.
Topics: Acetazolamide; Adult; Angiography; Carbonic Anhydrase Inhibitors; Carotid Stenosis; Collateral Circu | 2003 |
Stimulation of gastric pepsin secretion in man by hyperventilation and by diamox.
Topics: Acetazolamide; Aspartic Acid Endopeptidases; Digestion; Gastric Juice; Humans; Hyperventilation; Mal | 1959 |
Effect of acetazolamide on respiratory gas exchange during hyperventilation in man.
Topics: Acetazolamide; Cell Respiration; Hyperventilation; Respiration; Respiratory Physiological Phenomena | 1962 |
EFFECTS OF ACID-BASE CHANGES AND CARBONIC ANHYDRASE INHIBITION ON PANCREATIC SECRETION.
Topics: Acetazolamide; Acidosis; Alkalosis; Animals; Bicarbonates; Carbonic Anhydrase Inhibitors; Carbonic A | 1963 |
CORTICAL CO2 TENSION AND NEURONAL EXCITABILITY.
Topics: Acetazolamide; Brain; Carbon Dioxide; Cats; Cerebral Cortex; Cerebrovascular Circulation; Electrophy | 1965 |
Effect of hypercapnea and hyperventilation on human intraocular pressure general anaesthesia following acetazolamide administration.
Topics: Acetazolamide; Adult; Anesthesia, General; Carbon Dioxide; Female; Humans; Hydrogen-Ion Concentratio | 1980 |
Influence of different techniques of breath holding on the measurement of cerebrovascular reserve in carotid artery disease.
Topics: Acetazolamide; Blood Flow Velocity; Carotid Artery Diseases; Carotid Stenosis; Cerebral Arteries; Ce | 1996 |
Posthyperventilatory steal response in chronic cerebral hemodynamic stress: a positron emission tomography study.
Topics: Acetazolamide; Administration, Inhalation; Adult; Aged; Blood Volume; Brain; Brain Ischemia; Carbon | 1998 |
Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity.
Topics: Acetazolamide; Aged; Arterial Occlusive Diseases; Blood Flow Velocity; Brain; Carbon Dioxide; Cerebr | 1999 |
Metabolic acidosis and hyperventilation induced by acetazolamide in patients with central nervous system pathology.
Topics: Acetazolamide; Acidosis; Adult; Carbonic Anhydrase Inhibitors; Craniocerebral Trauma; Female; Headac | 2000 |
[Cerebral blood flow reactivity to hyperventilation in children with spontaneous occlusion of the circle of willis (moyamoya disease)].
Topics: Acetazolamide; Adolescent; Cerebral Revascularization; Cerebrovascular Circulation; Child; Child, Pr | 1992 |
A nineteen-year-old man with altered mental status.
Topics: Acetazolamide; Adult; Carbamazepine; Diagnosis, Differential; Drug Interactions; Electroencephalogra | 1992 |
Influence of acid-base status on plasma catecholamines during exercise in normal humans.
Topics: Acetazolamide; Acid-Base Equilibrium; Adult; Blood Pressure; Epinephrine; Exercise; Heart Rate; Huma | 1990 |
Ventilatory response to carbonic anhydrase inhibition in cats: effects of acetazolamide in intact vs peripherally chemodenervated animals.
Topics: Acetazolamide; Animals; Carotid Body; Cats; Denervation; Female; Hyperventilation; Male; Respiration | 1988 |
The effect of carbonic anhydrase inhibition on the canine in vivo H + -P CO2 relationship.
Topics: Acetazolamide; Animals; Blood; Buffers; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhy | 1972 |
Carbon dioxide excretion and pH-variations in diving ducks after carbonic anhydrase inhibition.
Topics: Acetazolamide; Acidosis; Animals; Asphyxia; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic | 1967 |
[Methods for controlling intracranial pressure].
Topics: Acetazolamide; Adrenal Cortex Hormones; Anesthetics; Antihypertensive Agents; Humans; Hypertonic Sol | 1972 |
Effects of hyperventilation, hypocapnia, and acetazolamide on experimental cerebral ischemia and infarction.
Topics: Acetazolamide; Animals; Brain Edema; Carbon Dioxide; Cats; Cerebrovascular Circulation; Cerebrovascu | 1972 |
Molecular CO 2 is inert on carotid chemoreceptor: demonstration by inhibition of carbonic anhydrase.
Topics: Acetazolamide; Animals; Blood; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carotid Body; Dogs; Hy | 1971 |
[Shifts of the acid-base equilibrium in chronic pulmonary insufficiency].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Digitoxin; Furosemide; Humans; Hydrogen | 1965 |
Effects of Pco2 acetazolamide and ouabain on volume and composition of choroid-plexus fluid.
Topics: Acetazolamide; Animals; Blood Gas Analysis; Carbon Dioxide; Cats; Cerebrospinal Fluid; Choroid Plexu | 1965 |