acetazolamide has been researched along with Hyperplasia in 5 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Investigations of MK-0927 and acetazolamide, both carbonic anhydrase inhibitors (CAIs), showed that urothelial hyperplasia develops in rats and mice, but not in rabbits, dogs, or monkeys." | 3.68 | Urothelial hyperplasia induced by carbonic anhydrase inhibitors (CAIs) in animals and its relationship to urinary Na and pH. ( Boussiquet-Leroux, C; Durand-Cavagna, G; Gordon, LR; Owen, RA; Peter, CP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| West, RW | 2 |
| Frith, CH | 2 |
| Stanley, JW | 2 |
| Jackson, CD | 2 |
| Fukushima, S | 1 |
| Hagiwara, A | 1 |
| Ogiso, T | 1 |
| Shibata, M | 1 |
| Ito, N | 1 |
| Molon-Noblot, S | 1 |
| Boussiquet-Leroux, C | 2 |
| Owen, RA | 2 |
| Irisarri, E | 1 |
| Durand-Cavagna, G | 2 |
| Peter, CP | 2 |
| Duprat, P | 1 |
| Gordon, LR | 1 |
5 other studies available for acetazolamide and Hyperplasia
| Article | Year |
|---|---|
The role of urinary physiological changes in the genesis of urothelial lesions in mice given 4-ethylsulfonylnaphthalene-1-sulfonamide, acetazolamide, and oxamide.
Topics: Acetazolamide; Amino Acids; Animals; Crystallization; Diet; Dose-Response Relationship, Drug; Epithe | 1984 |
Urothelial lesions in mice given 4-ethylsulfonylnaphthalene-1-sulfonamide, acetazolamide, and oxamide.
Topics: Acetazolamide; Amino Acids; Animals; Epithelium; Female; Hyperplasia; Male; Mice; Mice, Inbred BALB | 1984 |
Promoting effects of various chemicals in rat urinary bladder carcinogenesis initiated by N-nitroso-n-butyl-(4-hydroxybutyl)amine.
Topics: Acetazolamide; Allopurinol; Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Carci | 1983 |
Rat urinary bladder hyperplasia induced by oral administration of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Epithelium; Hyperplasia; Male; Microscopy, El | 1992 |
Urothelial hyperplasia induced by carbonic anhydrase inhibitors (CAIs) in animals and its relationship to urinary Na and pH.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Dogs; Female; Hydrogen-Ion Concentration; Hyp | 1992 |