Page last updated: 2024-10-22

acetazolamide and Hyperoxia

acetazolamide has been researched along with Hyperoxia in 9 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the variations of preretinal oxygen partial pressure (Po(2)) in normal and in ischemic postexperimental branch retinal vein occlusion (BRVO) areas, during normoxia, hyperoxia (100% O(2)), and carbogen (95% O(2), 5% CO(2)) breathing before and after intravenous injection of acetazolamide."7.72Experimental retinal vein occlusion: effect of acetazolamide and carbogen (95% O2/5% CO2) on preretinal PO2. ( Munoz, JL; Petropoulos, IK; Pournaras, CJ; Pournaras, JA, 2004)
"The effect of carbonic anhydrase inhibition with acetazolamide (Acz, 10 mg/kg) on the ventilatory response to an abrupt switch into hyperoxia (end-tidal PO2 = 450 Torr) and hypoxia (end-tidal PO2 = 50 Torr) was examined in five male subjects [30 +/- 3 (SE) yr]."5.09Peripheral chemoreceptor function after carbonic anhydrase inhibition during moderate-intensity exercise. ( Cunningham, DA; Kowalchuk, JM; Paterson, DH; Scheuermann, BW, 1999)
" The study was conducted to evaluate optic disc PO(2) variations during normoxia, hyperoxia (100% O(2)), and carbogen breathing (95% O(2), 5% CO(2)), before and after intravenous administration of acetazolamide."3.73Effect of carbogen breathing and acetazolamide on optic disc PO2. ( Munoz, JL; Petropoulos, IK; Pournaras, CJ; Pournaras, JA, 2005)
"To evaluate the variations of preretinal oxygen partial pressure (Po(2)) in normal and in ischemic postexperimental branch retinal vein occlusion (BRVO) areas, during normoxia, hyperoxia (100% O(2)), and carbogen (95% O(2), 5% CO(2)) breathing before and after intravenous injection of acetazolamide."3.72Experimental retinal vein occlusion: effect of acetazolamide and carbogen (95% O2/5% CO2) on preretinal PO2. ( Munoz, JL; Petropoulos, IK; Pournaras, CJ; Pournaras, JA, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kealy, J1
Bennett, R1
Lowry, JP1
Elliott, JE1
Friedman, JM1
Futral, JE1
Goodman, RD1
Lovering, AT1
Teppema, LJ2
van Dorp, EL1
Dahan, A2
Russell, DM1
Garry, EM1
Taberner, AJ1
Barrett, CJ1
Paton, JF1
Budgett, DM1
Malpas, SC1
Pournaras, JA2
Petropoulos, IK2
Munoz, JL2
Pournaras, CJ2
Scheuermann, BW1
Kowalchuk, JM2
Paterson, DH2
Cunningham, DA2
Vovk, A1
Duffin, J1
Olievier, CN1

Trials

2 trials available for acetazolamide and Hyperoxia

ArticleYear
Arterial [H+] and the ventilatory response to hypoxia in humans: influence of acetazolamide-induced metabolic acidosis.
    American journal of physiology. Lung cellular and molecular physiology, 2010, Volume: 298, Issue:1

    Topics: Acetazolamide; Acidosis, Respiratory; Bicarbonates; Carbon Dioxide; Female; Humans; Hyperoxia; Hypox

2010
Peripheral chemoreceptor function after carbonic anhydrase inhibition during moderate-intensity exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 86, Issue:5

    Topics: Acetazolamide; Adult; Bicycling; Blood Gas Analysis; Carbon Dioxide; Carbonic Anhydrase Inhibitors;

1999

Other Studies

7 other studies available for acetazolamide and Hyperoxia

ArticleYear
Simultaneous recording of hippocampal oxygen and glucose in real time using constant potential amperometry in the freely-moving rat.
    Journal of neuroscience methods, 2013, Apr-30, Volume: 215, Issue:1

    Topics: Acetazolamide; Analysis of Variance; Animals; Chloral Hydrate; Computer Systems; Dimethyl Sulfoxide;

2013
Sildenafil, nifedipine and acetazolamide do not allow for blood flow through intrapulmonary arteriovenous anastomoses during exercise while breathing 100% oxygen.
    Experimental physiology, 2014, Dec-01, Volume: 99, Issue:12

    Topics: Acetazolamide; Adult; Arteriovenous Anastomosis; Blood Flow Velocity; Exercise; Exercise Test; Femal

2014
A fully implantable telemetry system for the chronic monitoring of brain tissue oxygen in freely moving rats.
    Journal of neuroscience methods, 2012, Mar-15, Volume: 204, Issue:2

    Topics: Acetazolamide; Animals; Biosensing Techniques; Brain; Carbonic Anhydrase Inhibitors; Electrodes, Imp

2012
Experimental retinal vein occlusion: effect of acetazolamide and carbogen (95% O2/5% CO2) on preretinal PO2.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:10

    Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Hyperoxia; Injections, Intrav

2004
Effect of carbogen breathing and acetazolamide on optic disc PO2.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:11

    Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Hyperoxia; Injections, Intrav

2005
Changes in chemoreflex characteristics following acute carbonic anhydrase inhibition in humans at rest.
    Experimental physiology, 2000, Volume: 85, Issue:6

    Topics: Acetazolamide; Adult; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Chemoreceptor Cells; Female; Hu

2000
Low-dose acetazolamide reduces CO(2)-O(2) stimulus interaction within the peripheral chemoreceptors in the anaesthetised cat.
    The Journal of physiology, 2001, Nov-15, Volume: 537, Issue:Pt 1

    Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Cats; Chemoreceptor Cells; Do

2001