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acetazolamide and Hyperkalemia

acetazolamide has been researched along with Hyperkalemia in 35 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"We present the case of a 42-year-old man with moyamoya disease presenting for cerebral revascularization surgery who developed critical hyperkalemia following a single intravenous (iv) dose of 1000 mg of acetazolamide 1 day preoperatively for a cerebrovascular reactivity study."7.96Paradoxical Critical Hyperkalemia After Acetazolamide for Cerebrovascular Reactivity Study: A Case Report. ( Burbridge, MA; Jaffe, RA, 2020)
"Horses with hyperkalaemic periodic paralysis were challenged with an oral dose of potassium chloride, and the prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide was evaluated, with at least three weeks separating the trials of each drug."7.69Prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide in horses with hyperkalaemic periodic paralysis. ( Beech, J; Lindborg, S, 1995)
"Hyperkalemia is commonly encountered in patients who receive a renal transplant and the immunosuppressive drug, cyclosporine."7.68Studies to determine the basis for hyperkalemia in recipients of a renal transplant who are treated with cyclosporine. ( Albert, S; Carlisle, EJ; Ethier, JH; Halperin, ML; Kamel, KS; Levin, A; Quaggin, S, 1992)
"We studied the effect of acetazolamide on plasma potassium in normals and in two patients with hyperkalemic periodic paralysis."7.66Acute effects of acetazolamide in hyperkalemic periodic paralysis. ( Griggs, RC; Lewis, ED; Moxley, RT; Riggs, JE, 1981)
"We present the case of a 42-year-old man with moyamoya disease presenting for cerebral revascularization surgery who developed critical hyperkalemia following a single intravenous (iv) dose of 1000 mg of acetazolamide 1 day preoperatively for a cerebrovascular reactivity study."3.96Paradoxical Critical Hyperkalemia After Acetazolamide for Cerebrovascular Reactivity Study: A Case Report. ( Burbridge, MA; Jaffe, RA, 2020)
"Horses with hyperkalaemic periodic paralysis were challenged with an oral dose of potassium chloride, and the prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide was evaluated, with at least three weeks separating the trials of each drug."3.69Prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide in horses with hyperkalaemic periodic paralysis. ( Beech, J; Lindborg, S, 1995)
"Hyperkalemia is commonly encountered in patients who receive a renal transplant and the immunosuppressive drug, cyclosporine."3.68Studies to determine the basis for hyperkalemia in recipients of a renal transplant who are treated with cyclosporine. ( Albert, S; Carlisle, EJ; Ethier, JH; Halperin, ML; Kamel, KS; Levin, A; Quaggin, S, 1992)
"We studied the effect of acetazolamide on plasma potassium in normals and in two patients with hyperkalemic periodic paralysis."3.66Acute effects of acetazolamide in hyperkalemic periodic paralysis. ( Griggs, RC; Lewis, ED; Moxley, RT; Riggs, JE, 1981)
"It is likely that this horse's dysphagia, with resultant weight loss and aspiration pneumonia, were clinical manifestations and consequences of HPP."1.29Laryngospasm, dysphagia, and emaciation associated with hyperkalemic periodic paralysis in a horse. ( Breazile, JE; Guglick, MA; MacAllister, CG, 1996)
"Hyperkalemia was found in foals 1 and 4."1.28Respiratory stridor associated with polymyopathy suspected to be hyperkalemic periodic paralysis in four quarter horse foals. ( Child, G; Ingram, JT; Kiper, ML; MacAllister, CG; Stashak, TS; Tarr, S; Traub-Dargatz, JL, 1992)
"Acetazolamide was given to 11 patients but failed to increase fractional potassium excretion to normal."1.26Hyperkalemic distal renal tubular acidosis associated with obstructive uropathy. ( Arruda, JA; Batlle, DC; Kurtzman, NA, 1981)
"Two patients with long-standing systemic lupus erythematosus were found to have persistent hyperkalemia."1.26Impaired renal tubular potassium secretion in systemic lupus erythematosus. ( Agus, ZS; Cooke, CR; Cox, M; DeFronzo, RA; Goldberg, M; Myers, AR, 1977)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199024 (68.57)18.7374
1990's8 (22.86)18.2507
2000's1 (2.86)29.6817
2010's1 (2.86)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Burbridge, MA1
Jaffe, RA1
Lehmann-Horn, F1
Orth, M1
Kuhn, M1
Jurkat-Rott, K1
ALLSOP, JL1
GOULSTON, K1
JOHNSTON, C1
KELLY, D1
RAIL, L1
CARSON, MJ1
PEARSON, CM2
SAMAHA, FJ1
ILIESCU, CC1
KLEINERMAN, L1
MOSELEY, V1
BAROODY, NB1
Caramelo, C1
Albalate, M1
Tejedor, A1
Alcázar, R1
Baldoví, S1
García Pérez, A1
Marín, M1
Layzer, RB1
Lovelace, RE1
Rowland, LP3
Riggs, JE1
Griggs, RC3
Moxley, RT1
Lewis, ED1
Monclair, T1
Sejersted, OM1
Kiil, F2
Batlle, DC1
Arruda, JA1
Kurtzman, NA1
Tengan, CH1
De Oliveira, AS1
Gabbai, AA1
Ptáĉek, LJ1
Tawil, R1
Meola, G1
McManis, P1
Barohn, RJ1
Mendell, JR1
Harris, C1
Spitzer, R1
Santiago, F1
Ghosh, D1
Trivedi, N1
Kohli, A1
Mithal, A1
Stokke, ES1
Naess, PA1
Ostensen, J1
Langberg, HC1
Beech, J1
Lindborg, S1
Guglick, MA1
MacAllister, CG2
Breazile, JE1
DeFronzo, RA1
Cooke, CR1
Goldberg, M1
Cox, M1
Myers, AR1
Agus, ZS1
Il'ina, NA1
Aver'ianov, IuN1
Kamel, KS1
Ethier, JH1
Quaggin, S1
Levin, A1
Albert, S1
Carlisle, EJ1
Halperin, ML1
Traub-Dargatz, JL1
Ingram, JT1
Stashak, TS1
Kiper, ML1
Tarr, S1
Child, G1
Greenberg, A1
Ashouri, OS1
Mertens, HG1
Lurati, M1
Führ, J1
Hoskins, B2
Jarrell, MA2
Maren, TH2
Lisak, RP2
Lebeau, J2
Tucker, SH2
Vroom, FQ1
Leiter, L1
Radó, JP1
Marosi, J1
Takó, J1
Dévényi, I1
Levitt, LP1
Rose, LI1
Dawson, DM1
Resnick, JS1
Engel, WK1
Stam, AC1
Arnold, JE1
Healy, JK1

Reviews

1 review available for acetazolamide and Hyperkalemia

ArticleYear
Combinations of diuretics in the treatment of edema.
    American heart journal, 1970, Volume: 80, Issue:3

    Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu

1970

Trials

1 trial available for acetazolamide and Hyperkalemia

ArticleYear
Acetazolamide prophylaxis in hypokalemic periodic paralysis.
    The New England journal of medicine, 1968, Mar-14, Volume: 278, Issue:11

    Topics: Acetazolamide; Adult; Child; Humans; Hyperkalemia; Hypokalemia; Male; Paralyses, Familial Periodic;

1968

Other Studies

33 other studies available for acetazolamide and Hyperkalemia

ArticleYear
Paradoxical Critical Hyperkalemia After Acetazolamide for Cerebrovascular Reactivity Study: A Case Report.
    A&A practice, 2020, Feb-01, Volume: 14, Issue:3

    Topics: Acetazolamide; Administration, Intravenous; Adult; Disease Management; Humans; Hyperkalemia; Moyamoy

2020
A novel N440K sodium channel mutation causes myotonia with exercise-induced weakness--exclusion of CLCN1 exon deletion/duplication by MLPA.
    Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2011, Volume: 30, Issue:2

    Topics: Acetazolamide; Anti-Arrhythmia Agents; Anticonvulsants; Chloride Channels; Humans; Hyperkalemia; Hyp

2011
FAMILIAL HYPERKALAEMIC PERIODIC PARALYSIS.
    Australasian annals of medicine, 1964, Volume: 13

    Topics: Acetazolamide; Adolescent; Blood Chemical Analysis; Calcium; Electrocardiography; Electromyography;

1964
FAMILIAL HYPERKALEMIC PERIODIC PARALYSIS WITH MYOTONIC FEATURES.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: 17-Ketosteroids; Acetazolamide; Adolescent; Biopsy; Blood Chemical Analysis; Child; Dextroamphetamin

1964
THE PERIODIC PARALYSES: DIFFERENTIAL FEATURES AND PATHOLOGICAL OBSERVATIONS IN PERMANENT MYOPATHIC WEAKNESS.
    Brain : a journal of neurology, 1964, Volume: 87

    Topics: Acetazolamide; Drug Therapy; Epinephrine; Humans; Hydrochlorothiazide; Hydrocortisone; Hyperkalemia;

1964
HYPERKALEMIC PERIODIC PARALYSIS. A GENETIC STUDY, CLINICAL OBSERVATIONS, AND REPORT OF A NEW METHOD OF THERAPY.
    Archives of neurology, 1965, Volume: 12

    Topics: Acetazolamide; Amphetamine; Amphetamines; Chlorothiazide; Electromyography; Genetics, Medical; Human

1965
THE EFFECT OF REDUCTION OF BLOOD POTASSIUM LEVEL IN THE TREATMENT OF A-V BLOCK AND IN THE PREVENTION OF ADAMS-STOKES ATTACKS.
    Diseases of the chest, 1965, Volume: 47

    Topics: Acetazolamide; Adams-Stokes Syndrome; Adolescent; Adrenal Cortex Hormones; Chlorothiazide; Drug Ther

1965
Some observations on the use of acetazoleamide ("diamox") as an oral diuretic in various edematous states and in uremia with hyperkaliemia.
    American practitioner and digest of treatment, 1955, Volume: 6, Issue:4

    Topics: Acetazolamide; Blood; Calcium; Calcium, Dietary; Diuretics; Edema; Hyperkalemia; Uremia

1955
[Current use of acetazolamide as a diuretic: usefulness in refractory edema and in aldosterone-antagonist-related hyperkalemia].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2008, Volume: 28, Issue:2

    Topics: Acetazolamide; Aged; Aged, 80 and over; Diuretics; Edema; Female; Humans; Hyperkalemia; Male; Minera

2008
Hyperkalemic periodic paralysis.
    Archives of neurology, 1967, Volume: 16, Issue:5

    Topics: Acetazolamide; Adolescent; Adult; Aged; Child; Cold Temperature; Electromyography; Female; Glucose T

1967
Acute effects of acetazolamide in hyperkalemic periodic paralysis.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Acetazolamide; Adult; Female; Humans; Hyperkalemia; Insulin; Male; Paralysis

1981
Influence of plasma potassium concentration on the capacity for sodium reabsorption in the diluting segment of the kidney.
    Scandinavian journal of clinical and laboratory investigation, 1980, Volume: 40, Issue:1

    Topics: Absorption; Acetazolamide; Animals; Blood Glucose; Dogs; Energy Metabolism; Female; Hyperkalemia; Hy

1980
Hyperkalemic distal renal tubular acidosis associated with obstructive uropathy.
    The New England journal of medicine, 1981, Feb-12, Volume: 304, Issue:7

    Topics: Acetazolamide; Acidosis, Renal Tubular; Aged; Aldosterone; Diagnosis, Differential; Glomerular Filtr

1981
[Periodic paralysis. Clinical analysis in 20 patients].
    Arquivos de neuro-psiquiatria, 1994, Volume: 52, Issue:4

    Topics: Acetazolamide; Adolescent; Adult; Child; Child, Preschool; Electromyography; Female; Humans; Hyperka

1994
Sodium channel mutations in acetazolamide-responsive myotonia congenita, paramyotonia congenita, and hyperkalemic periodic paralysis.
    Neurology, 1994, Volume: 44, Issue:8

    Topics: Acetazolamide; Autoradiography; Base Sequence; Female; Humans; Hyperkalemia; Male; Molecular Sequenc

1994
Hyperkalemic periodic paralysis associated with thyrotoxicosis.
    The Journal of the Association of Physicians of India, 1993, Volume: 41, Issue:4

    Topics: Acetazolamide; Adult; Carbimazole; Electromyography; Humans; Hyperkalemia; Male; Paralysis; Thyrotox

1993
Plasma potassium concentration as a determinant of proximal tubular NaCl and NaHCO3 reabsorption in dog kidneys.
    Acta physiologica Scandinavica, 1993, Volume: 148, Issue:1

    Topics: Absorption; Acetazolamide; Amiloride; Animals; Bicarbonates; Biological Transport; Bumetanide; Dogs;

1993
Prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide in horses with hyperkalaemic periodic paralysis.
    Research in veterinary science, 1995, Volume: 59, Issue:2

    Topics: Acetazolamide; Animals; Diuretics; Horse Diseases; Horses; Hydrochlorothiazide; Hyperkalemia; Male;

1995
Laryngospasm, dysphagia, and emaciation associated with hyperkalemic periodic paralysis in a horse.
    Journal of the American Veterinary Medical Association, 1996, Jul-01, Volume: 209, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Deglutition Disorders; Diagnosis, Differential; Emaciation;

1996
Impaired renal tubular potassium secretion in systemic lupus erythematosus.
    Annals of internal medicine, 1977, Volume: 86, Issue:3

    Topics: Acetazolamide; Adult; Aldosterone; Female; Fludrocortisone; Furosemide; Humans; Hyperkalemia; Kidney

1977
[Treatment of paroxysmal myoplegia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:6

    Topics: Acetazolamide; Adolescent; Adult; Female; Humans; Hyperkalemia; Hypokalemia; Paralyses, Familial Per

1975
Studies to determine the basis for hyperkalemia in recipients of a renal transplant who are treated with cyclosporine.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:8

    Topics: Acetazolamide; Bicarbonates; Cyclosporine; Female; Fludrocortisone; Humans; Hyperkalemia; Kidney; Ki

1992
Respiratory stridor associated with polymyopathy suspected to be hyperkalemic periodic paralysis in four quarter horse foals.
    Journal of the American Veterinary Medical Association, 1992, Jul-01, Volume: 201, Issue:1

    Topics: Acetazolamide; Animals; Arytenoid Cartilage; Calcium; Electromyography; Fluid Therapy; Horse Disease

1992
What's new in diuretic therapy.
    American family physician, 1986, Volume: 33, Issue:5

    Topics: Acetazolamide; Acid-Base Imbalance; Biological Transport; Diuretics; Drug Resistance; Ethacrynic Aci

1986
Hyperkalemic distal renal tubular acidosis and selective aldosterone deficiency. Combination in a patient with lead nephropathy.
    Archives of internal medicine, 1985, Volume: 145, Issue:7

    Topics: Acetazolamide; Acidosis, Renal Tubular; Aldosterone; Electrolytes; Female; Fludrocortisone; Furosemi

1985
Primary periodic paralysis associated with hyperkalemic and hypokalemic attacks and with hemolytic bilirubinemia.
    European neurology, 1968, Volume: 1, Issue:4

    Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Bilirubin; Dexamethasone

1968
Effects of carbonic anhydrase inhibitors on potassium exchange in human red blood cells.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 209, Issue:1

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Chlorides; Erythrocytes; Female; Hematocrit; He

1974
Hyperkalemic periodic paralysis and cardiac arrhythmia.
    Neurology, 1972, Volume: 22, Issue:8

    Topics: Acetazolamide; Adolescent; Arrhythmias, Cardiac; Blood Glucose; Electrocardiography; Electromyograph

1972
Acetazolamide and potassium flux in red blood cells. Studies in patients with hyperkalemic periodic paralysis.
    Archives of neurology, 1974, Volume: 31, Issue:3

    Topics: Acetazolamide; Administration, Oral; Adult; Bicarbonates; Child, Preschool; Erythrocytes; Female; Hu

1974
Hyperkalemic intermittent paralysis associated with spironolactone in a patient with cardiac cirrhosis.
    American heart journal, 1968, Volume: 76, Issue:3

    Topics: Acetazolamide; Adult; Aldosterone; Ascites; Female; Furosemide; Heart Failure; Heart Valve Diseases;

1968
Hypokalemic periodic paralysis with arrhythmia.
    The New England journal of medicine, 1972, Feb-03, Volume: 286, Issue:5

    Topics: Acetazolamide; Arrhythmias, Cardiac; Child; Electrocardiography; Heart; Humans; Hyperkalemia; Male;

1972
Hyperkalemic periodic paralysis with cardiac arrhythmia.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Acetazolamide; Adolescent; Child; Female; Humans; Hyperkalemia; Paralyses, Familial Periodic; Phenyt

1970
Hyperkalemia, hypertension and systemic acidosis without renal failure associated with a tubular defect in potassium excretion.
    The American journal of medicine, 1969, Volume: 47, Issue:3

    Topics: Acetazolamide; Acidosis, Renal Tubular; Adolescent; Adult; Aminohippuric Acids; Bicarbonates; Blood

1969