acetazolamide has been researched along with Hemorrhage, Retinal in 16 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "High-altitude retinal hemorrhage may be related to similar vascular events in the retinal circulation." | 2.37 | Altitude-related illness. ( Foulke, GE, 1985) |
| "After surgery, the clinical signs of elevated intracranial pressure transiently worsened." | 1.40 | Visual and neurologic deterioration in otogenic lateral sinus thrombosis: 15 year experience. ( Csákányi, Z; Katona, G; Kollár, K; Kovács, É; Kulcsár, A; Mellár, M; Móser, J; Rosdy, B; Várallyay, G, 2014) |
| "A 30-year-old woman had bilateral anterior ischemic optic neuropathy after undergoing large-volume liposuction." | 1.32 | Bilateral anterior ischemic optic neuropathy after liposuction. ( Foroozan, R; Varon, J, 2004) |
| "Mild forms of acute mountain sickness are treated by a rest day, whereas patients with severe disease should descend as soon as possible." | 1.26 | [Incidence, prevention and therapy of acute mountain sickness]. ( Oelz, O, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosdy, B | 1 |
| Csákányi, Z | 1 |
| Kollár, K | 1 |
| Móser, J | 1 |
| Mellár, M | 1 |
| Kulcsár, A | 1 |
| Kovács, É | 1 |
| Várallyay, G | 1 |
| Katona, G | 1 |
| Wall, M | 1 |
| Thurtell, MJ | 1 |
| Skone, K | 1 |
| Abbott, J | 1 |
| Wacogne, ID | 1 |
| Foroozan, R | 1 |
| Varon, J | 1 |
| Stokes, HR | 1 |
| Houston, CS | 2 |
| Oelz, O | 1 |
| MacLaren, RE | 1 |
| Ogawa, T | 1 |
| Kitaoka, T | 1 |
| Mera, A | 1 |
| Saitoh, AK | 1 |
| Amemiya, T | 1 |
| Wood, CM | 1 |
| Clarke, C | 1 |
| Foulke, GE | 1 |
| Ffytche, TJ | 1 |
| Grant, WM | 1 |
| Frayser, R | 1 |
| Bryan, AC | 1 |
| Rennie, ID | 1 |
| Gray, G | 1 |
| Paufique, L | 1 |
| Ravault, MP | 1 |
| Malterre, M | 1 |
| Sinno, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Double-blind, Randomized, Placebo-controlled Study of Weight-Reduction and/or Low Sodium Diet Plus Acetazolamide vs Diet Plus Placebo in Subjects With Idiopathic Intracranial Hypertension With Mild Visual Loss[NCT01003639] | Phase 2/Phase 3 | 165 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Treatment Effects on the Primary Outcome Variable, Mean change From Baseline to Month 6 in Perimetric Mean Deviation (PMD) in the Study Eye. Perimetric mean deviation is a measure of global visual field loss (mean deviation from age-corrected normal values), with a range of 2 to -32 dB; larger negative values indicate greater vision loss. (NCT01003639)
Timeframe: base line and 6 months
| Intervention | dB (Mean) |
|---|---|
| Acetazolamide | 1.43 |
| Sugar Pill | 0.71 |
Mean change at month 6 as compared to baseline. Frisén papilledema grade is an ordinal scale that uses ocular fundus features to rate the severity of papilledema; grade 0 indicates no features of papilledema and grade 5 indicates severe papilledema. (NCT01003639)
Timeframe: Baseline and 6 Months
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Study eye | Fellow eye | |
| Acetazolamide | -1.31 | -1.14 |
| Sugar Pill | -0.61 | -0.52 |
(NCT01003639)
Timeframe: Baseline
| Intervention | correct letters (Mean) | |
|---|---|---|
| Study Eye | Fellow Eye | |
| Acetazolamide | 56.8 | 58.3 |
| Sugar Pill | 55.6 | 56.2 |
Visual Function Questionnaire (VFQ-25) total score, VFQ-25 10-item neuro-ophthalmic supplement total score: 0-100 (higher scores indicate better quality of life) (NCT01003639)
Timeframe: baseline
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Total score | 10-item neuro-ophthalmic supplement | |
| Acetazolamide | 83.8 | 75.8 |
| Sugar Pill | 82.1 | 75.0 |
2 reviews available for acetazolamide and Hemorrhage, Retinal
| Article | Year |
|---|---|
Altitude-related illness.
Topics: Acetazolamide; Altitude Sickness; Atmospheric Pressure; Brain Edema; Carbon Dioxide; Cardiovascular | 1985 |
A rationalization of treatment of central retinal artery occlusion.
Topics: Acetazolamide; Arterial Occlusive Diseases; Arteriosclerosis; Arteritis; Blood Sedimentation; Emboli | 1974 |
1 trial available for acetazolamide and Hemorrhage, Retinal
| Article | Year |
|---|---|
Optic disc haemorrhages at baseline as a risk factor for poor outcome in the Idiopathic Intracranial Hypertension Treatment Trial.
Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Pressure; Combined Modality | 2017 |
13 other studies available for acetazolamide and Hemorrhage, Retinal
| Article | Year |
|---|---|
Visual and neurologic deterioration in otogenic lateral sinus thrombosis: 15 year experience.
Topics: Acetazolamide; Acute Disease; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; C-Reactive Pro | 2014 |
From menorrhagia to manometers.
Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Anemia; Coombs Test; Diuretics; Fatigue; Female; | 2012 |
Bilateral anterior ischemic optic neuropathy after liposuction.
Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Jugular Veins; Lipectomy; Magne | 2004 |
Retinal vascular occlusive disease.
Topics: Acetazolamide; Aged; Carbon Dioxide; Female; Giant Cell Arteritis; Glaucoma; Humans; Intraocular Pre | 1967 |
Altitude illness.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Atmospheric Pressure; Brain Edema; Diuretics | 1984 |
[Incidence, prevention and therapy of acute mountain sickness].
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Fluid Therapy; Humans; Hypoxia; Mountaineering; Nepal | 1982 |
Retinal haemorrhage in Himalayan mountaineers.
Topics: Acetazolamide; Adult; Altitude Sickness; Female; Hemoglobins; Humans; Intraocular Pressure; Male; Mo | 1995 |
Treatment for subretinal hemorrhage in the macula: pneumatic displacement of hemorrhages.
Topics: Acetazolamide; Aged; Aged, 80 and over; Female; Fundus Oculi; Humans; Injections; Intraocular Pressu | 2000 |
The medical management of retrobulbar haemorrhage complicating facial fractures: a case report.
Topics: Acetazolamide; Adult; Blindness; Humans; Hydrocortisone; Hyphema; Male; Mannitol; Orbital Fractures; | 1989 |
High altitude cerebral oedema.
Topics: Acetazolamide; Adolescent; Altitude Sickness; Brain Edema; Cerebrovascular Disorders; Female; Humans | 1988 |
Shallowing of the anterior chamber following occlusion of the central retinal vein.
Topics: Acetazolamide; Adult; Aged; Anterior Chamber; Eye Diseases; Female; Glaucoma; Humans; Male; Pilocarp | 1973 |
Retinal hemorrhage at high altitude.
Topics: Acetazolamide; Adaptation, Physiological; Altitude; Fundus Oculi; Furosemide; Humans; Papilledema; P | 1970 |
[Retinal hemorrhage after medical sedation of an attack of acute glaucoma].
Topics: Acetazolamide; Aged; Female; Glaucoma; Humans; Retinal Hemorrhage | 1965 |