acetazolamide has been researched along with Hakim Syndrome in 19 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide SPECT was performed in all patients, and mini-mental state examination (MMSE) was performed before and 1 month after the surgery in group III." | 2.78 | Preoperative acetazolamide SPECT is useful for predicting outcome of shunt operation in idiopathic normal pressure hydrocephalus patients. ( Fujimoto, Y; Kawanishi, Y; Masahira, N; Shimizu, K; Yamada, SM, 2013) |
| "In high-pressure hydrocephalus, the volume of the CSF is increased, resulting either from increased production or reduced absorption." | 2.48 | [Headache from increased cerebrospinal fluid pressure]. ( Göbel, C; Göbel, H; Heinze, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, SM | 1 |
| Masahira, N | 1 |
| Kawanishi, Y | 1 |
| Fujimoto, Y | 1 |
| Shimizu, K | 1 |
| Williams, MA | 1 |
| Alperin, N | 3 |
| Oliu, CJ | 1 |
| Bagci, AM | 1 |
| Lee, SH | 1 |
| Kovanlikaya, I | 2 |
| Adams, D | 1 |
| Katzen, H | 2 |
| Ivkovic, M | 2 |
| Heier, L | 2 |
| Relkin, N | 3 |
| Gilbert, GJ | 1 |
| Olio, C | 1 |
| Reiss-Zimmermann, M | 1 |
| Preuss, M | 1 |
| Hoffmann, KT | 1 |
| Chen, YF | 1 |
| Wang, YH | 1 |
| Hsiao, JK | 1 |
| Lai, DM | 1 |
| Liao, CC | 1 |
| Tu, YK | 1 |
| Liu, HM | 1 |
| Chang, CC | 3 |
| Asada, H | 1 |
| Mimura, T | 1 |
| Suzuki, S | 1 |
| Sakellaridis, N | 1 |
| Stavropoulos, S | 1 |
| Göbel, H | 1 |
| Göbel, C | 1 |
| Heinze, A | 1 |
| Klinge, P | 1 |
| Berding, G | 1 |
| Brinker, T | 1 |
| Schuhmann, M | 1 |
| Weckesser, E | 1 |
| Knapp, WH | 1 |
| Samii, M | 1 |
| Kuwana, N | 2 |
| Ito, S | 2 |
| Yokoyama, T | 1 |
| Kanno, H | 1 |
| Yamamoto, I | 1 |
| Miyati, T | 1 |
| Mase, M | 1 |
| Banno, T | 1 |
| Kasuga, T | 1 |
| Yamada, K | 1 |
| Fujita, H | 1 |
| Koshida, K | 1 |
| Sanada, S | 1 |
| Onoguchi, M | 1 |
| Miyake, H | 2 |
| Ohta, T | 1 |
| Kajimoto, Y | 1 |
| Deguchi, J | 1 |
| Ikegami, T | 1 |
| Papanicolaou, N | 1 |
| McNeil, BJ | 1 |
| Funkenstein, HH | 1 |
| Sudarsky, LR | 1 |
| Fisher, RG | 1 |
| Adams, RD | 1 |
| Yoshida, S | 1 |
| Yonekawa, Y | 1 |
| Kawano, T | 1 |
| Goto, Y | 1 |
| Yamashita, K | 1 |
| Kaku, Y | 1 |
| Aimard, G | 1 |
| Vighetto, A | 1 |
| Gabet, JY | 1 |
| Bret, P | 1 |
| Henry, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind Randomized Acetazolamide Trial in Normal Pressure Hydrocephalus[NCT04975269] | Phase 2 | 50 participants (Anticipated) | Interventional | 2022-02-17 | Recruiting | ||
| Acetazolamide for Treating NPH in Shunt-candidates Patients: an Open Label Feasibility Trial[NCT03779594] | Phase 2 | 15 participants (Anticipated) | Interventional | 2018-12-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for acetazolamide and Hakim Syndrome
| Article | Year |
|---|---|
[Headache from increased cerebrospinal fluid pressure].
Topics: Acetazolamide; Algorithms; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Shunts; Combined Modali | 2012 |
The cerebrospinal fluid.
Topics: Acetazolamide; Animals; Blood-Brain Barrier; Cerebrospinal Fluid; Cerebrospinal Fluid Shunts; Choroi | 1975 |
2 trials available for acetazolamide and Hakim Syndrome
| Article | Year |
|---|---|
Preoperative acetazolamide SPECT is useful for predicting outcome of shunt operation in idiopathic normal pressure hydrocephalus patients.
Topics: Acetazolamide; Cerebrospinal Fluid Shunts; Cerebrovascular Circulation; Female; Humans; Hydrocephalu | 2013 |
Cerebral haemodynamics in patients with hydrocephalus after subarachnoid haemorrhage due to ruptured aneurysm.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Brain; Cerebral Ventricles; Cereb | 2003 |
15 other studies available for acetazolamide and Hakim Syndrome
| Article | Year |
|---|---|
Comment: the trouble with "n" in normal-pressure hydrocephalus.
Topics: Acetazolamide; Brain; Female; Humans; Hydrocephalus, Normal Pressure; Male; Nerve Fibers, Myelinated | 2014 |
Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH.
Topics: Acetazolamide; Aged; Aged, 80 and over; Brain; Female; Gait; Humans; Hydrocephalus, Normal Pressure; | 2014 |
Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH.
Topics: Acetazolamide; Aged; Aged, 80 and over; Brain; Female; Gait; Humans; Hydrocephalus, Normal Pressure; | 2014 |
Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH.
Topics: Acetazolamide; Aged; Aged, 80 and over; Brain; Female; Gait; Humans; Hydrocephalus, Normal Pressure; | 2014 |
Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH.
Topics: Acetazolamide; Aged; Aged, 80 and over; Brain; Female; Gait; Humans; Hydrocephalus, Normal Pressure; | 2014 |
Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH.
Topics: Acetazolamide; Brain; Female; Humans; Hydrocephalus, Normal Pressure; Male; Nerve Fibers, Myelinated | 2014 |
MRI assessment of the effects of acetazolamide and external lumbar drainage in idiopathic normal pressure hydrocephalus.
Topics: Acetazolamide; Aged; Aged, 80 and over; Brain; Drainage; Female; Humans; Hydrocephalus, Normal Press | 2015 |
Normal pressure hydrocephalus: cerebral hemodynamic, metabolism measurement, discharge score, and long-term outcome.
Topics: Acetazolamide; Aged; Aged, 80 and over; Brain Chemistry; Cerebrovascular Circulation; Diuretics; Fem | 2008 |
A prospective study of cerebral blood flow and cerebrovascular reactivity to acetazolamide in 162 patients with idiopathic normal-pressure hydrocephalus.
Topics: Acetazolamide; Aged; Aged, 80 and over; Cerebrospinal Fluid Shunts; Cerebrovascular Circulation; Fem | 2009 |
Normal-pressure hydrocephalus and cerebral blood flow.
Topics: Acetazolamide; Aged; Brain; Carbonic Anhydrase Inhibitors; Cerebral Revascularization; Humans; Hydro | 2010 |
The role of cerebral blood flow and cerebrovascular reserve capacity in the diagnosis of chronic hydrocephalus--a PET-study on 60 patients.
Topics: Acetazolamide; Blood Flow Velocity; Cerebrospinal Fluid Shunts; Cerebrovascular Circulation; Humans; | 2002 |
Frequency analyses of CSF flow on cine MRI in normal pressure hydrocephalus.
Topics: Acetazolamide; Adult; Anticonvulsants; Atrophy; Blood Flow Velocity; Brain; Cerebrospinal Fluid; Cer | 2003 |
Diamox((R)) challenge test to decide indications for cerebrospinal fluid shunting in normal pressure hydrocephalus.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Brain; Female; Humans; Hydrocephalus, Normal Pressure | 1999 |
Impairment of cerebrovascular reactivity to acetazolamide in patients with normal pressure hydrocephalus.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Brain Injuries; Brain Neoplasms; Cerebrovascular Circ | 2000 |
Abnormal cisternogram associated with Diamox therapy.
Topics: Acetazolamide; Aged; Cisterna Magna; Dementia; Humans; Hydrocephalus; Hydrocephalus, Normal Pressure | 1978 |
Recent observations on normal pressure hydrocephalus.
Topics: Acetazolamide; Aged; Cerebral Angiography; Cerebrospinal Fluid Shunts; Electroencephalography; Hemat | 1975 |
[Changes in CSF pressure induced by acetazolamide administration test--as an indicator of shunt operation for so-called normal pressure hydrocephalus].
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Shu | 1991 |
[Acetazolamide: an alternative to shunting in normal pressure hydrocephalus? Preliminary results].
Topics: Acetazolamide; Aged; Aged, 80 and over; Cerebrospinal Fluid Shunts; Female; Follow-Up Studies; Human | 1990 |