Page last updated: 2024-10-22

acetazolamide and Glioblastoma with Sarcomatous Component

acetazolamide has been researched along with Glioblastoma with Sarcomatous Component in 1 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"Rats bearing 9L brain tumors in situ were imaged during inhalation of room air and after administration of 100% oxygen + acetazolamide (ACZ) injected 15 mg/kg intravenously."1.30Functional magnetic resonance (fMR) imaging of a rat brain tumor model: implications for evaluation of tumor microvasculature and therapeutic response. ( Chau, RI; Grossman, Z; Mazurchuk, R; Straubinger, RM; Zhou, R, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mazurchuk, R1
Zhou, R1
Straubinger, RM1
Chau, RI1
Grossman, Z1

Other Studies

1 other study available for acetazolamide and Glioblastoma with Sarcomatous Component

ArticleYear
Functional magnetic resonance (fMR) imaging of a rat brain tumor model: implications for evaluation of tumor microvasculature and therapeutic response.
    Magnetic resonance imaging, 1999, Volume: 17, Issue:4

    Topics: Acetazolamide; Animals; Brain; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Gliosarcoma; Image Pr

1999