Page last updated: 2024-10-22

acetazolamide and Glaucoma, Suspect

acetazolamide has been researched along with Glaucoma, Suspect in 69 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"To examine whether intraocular pressure (IOP) increases immediately after cataract surgery in eyes with pseudoexfoliation (PXF) syndrome and to assess whether orally administered acetazolamide can prevent the IOP elevation."9.27Intraocular pressure elevation after cataract surgery and its prevention by oral acetazolamide in eyes with pseudoexfoliation syndrome. ( Hayashi, K; Manabe, SI; Sato, T; Yoshida, M; Yoshimura, K, 2018)
"To confirm the prophylactic effect of oral acetazolamide against increased intraocular pressure (IOP) in the period immediately after cataract surgery in eyes with primary open-angle glaucoma (POAG) and to evaluate the appropriate administration time of oral acetazolamide to prevent IOP elevation."9.24Prophylactic Effect of Oral Acetazolamide against Intraocular Pressure Elevation after Cataract Surgery in Eyes with Glaucoma. ( Hayashi, K; Manabe, SI; Yoshida, M; Yoshimura, K, 2017)
"To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients."9.24Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. ( Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J, 2017)
"To determine the effect of oral acetazolamide on lowering the peak and duration of intraocular pressure (IOP) rise in glaucoma and glaucoma suspect patients, following intravitreal injection of ranibizumab for neovascular age-related macular degeneration."9.19Short-term intraocular pressure trends following intravitreal ranibizumab injections for neovascular age-related macular degeneration-the role of oral acetazolamide in protecting glaucoma patients. ( Allgar, V; Gale, RP; Murray, CD; Walters, G; Wood, D, 2014)
"To evaluate the effects of oral acetazolamide (ACZ), anterior chamber paracentesis (ACP), or topical brimonidine tartrate (BT) to reduce intraocular pressure (IOP) elevation after intravitreal bevacizumab injection (IVBI)."9.19Comparison of acetazolamide, brimonidine, and anterior chamber paracentesis for ocular hypertension control after initial intravitreal bevacizumab injection: a randomized clinical trial. ( Bonini-Filho, MA; Costa, R; Jorge, R; Katayama, BY; Martin, LF; Messias, AM; Paula, JS, 2014)
"To assess the effect of intraoperative acetazolamide (Diamox) on postoperative intraocular pressure (IOP) in gas-filled, vitrectomized eyes."9.09Intraoperative acetazolamide in the prevention of intraocular pressure rise after pars plana vitrectomy with fluid-gas exchange. ( Grand, MG; Ruby, AJ; Thomas, MA; Williams, D, 1999)
"The aim of this study was to evaluate the effectiveness of topical dorzolamide versus systemic acetazolamide in preventing the intraocular pressure (IOP) spike, following routine phacoemulsification surgery."9.08A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification surgery. ( Lukaris, A; Roberts-Harry, TJ; Rogers, ZA; Sells, M; Zohdy, GA, 1998)
"The study aimed to determine whether topical dorzolamide and systemic acetazolamide have an additive effect on intraocular pressure (IOP) and aqueous humor formation (AHF)."9.08Combination of systemic acetazolamide and topical dorzolamide in reducing intraocular pressure and aqueous humor formation. ( Hong, PH; Krupin, T; Rosenberg, LF; Ruderman, JM; Tang, LQ, 1998)
"To compare postoperative intraocular pressure (IOP) after administration of acetazolamide and timolol following phacoemulsification and intraocular lens implantation."9.08Timolol gel versus acetazolamide in the prophylaxis of ocular hypertension after phacoemulsification. ( Donnenfeld, ED; Kanellopoulos, AJ; Perry, HD, 1997)
"0% dorzolamide hydrochloride with oral acetazolamide in preventing intraocular pressure (IOP) rise following neodymium:YAG (Nd:YAG) laser posterior capsulotomy."9.08Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy. ( Baltatzis, S; Kokolakis, SN; Ladas, ID; Panagiotidis, D; Theodossiadis, GP; Zafirakis, P, 1997)
"To investigate the additive ocular hypotensive effect of latanoprost on the intraocular pressure (IOP) reduction induced by a suboptimal dose of acetazolamide, a carbonic anhydrase inhibitor."9.08Additive ocular hypotensive effect of latanoprost and acetazolamide. A short-term study in patients with elevated intraocular pressure. ( Greve, EL; Hoyng, PF; Rulo, AH, 1997)
"Prophylactic use of timolol gel for viscoelastic-induced ocular hypertension after PK appears to offer better IOP control than oral acetazolamide, with potentially fewer adverse systemic effects."9.08Comparison of topical timolol gel to oral acetazolamide in the prophylaxis of viscoelastic-induced ocular hypertension after penetrating keratoplasty. ( Donnenfeld, ED; Kanellopoulos, AJ; Perry, HD, 1997)
"This prospective study was done to compare the efficacy of timolol and acetazolamide in lowering the intraocular pressure (IOP) secondary to the use of sodium hyaluronate (Healon) in cataract surgery."9.07Effect of timolol vs. acetazolamide on sodium hyaluronate-induced rise in intraocular pressure after cataract surgery. ( Duperré, J; Grenier, B; Lambert, J; Lemire, J; Mihalovits, H; Sebag, M, 1994)
"Acetazolamide was capable of preventing the excessive IOP rise during dialysis."5.28Intraocular pressure changes during hemodialysis: prevention of excessive dialytic rise and development of severe metabolic acidosis following acetazolamide therapy. ( Cecchin, E; De Marchi, S; Tesio, F, 1989)
"To examine whether intraocular pressure (IOP) increases immediately after cataract surgery in eyes with pseudoexfoliation (PXF) syndrome and to assess whether orally administered acetazolamide can prevent the IOP elevation."5.27Intraocular pressure elevation after cataract surgery and its prevention by oral acetazolamide in eyes with pseudoexfoliation syndrome. ( Hayashi, K; Manabe, SI; Sato, T; Yoshida, M; Yoshimura, K, 2018)
"To confirm the prophylactic effect of oral acetazolamide against increased intraocular pressure (IOP) in the period immediately after cataract surgery in eyes with primary open-angle glaucoma (POAG) and to evaluate the appropriate administration time of oral acetazolamide to prevent IOP elevation."5.24Prophylactic Effect of Oral Acetazolamide against Intraocular Pressure Elevation after Cataract Surgery in Eyes with Glaucoma. ( Hayashi, K; Manabe, SI; Yoshida, M; Yoshimura, K, 2017)
"To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients."5.24Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. ( Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J, 2017)
"To evaluate the effects of oral acetazolamide (ACZ), anterior chamber paracentesis (ACP), or topical brimonidine tartrate (BT) to reduce intraocular pressure (IOP) elevation after intravitreal bevacizumab injection (IVBI)."5.19Comparison of acetazolamide, brimonidine, and anterior chamber paracentesis for ocular hypertension control after initial intravitreal bevacizumab injection: a randomized clinical trial. ( Bonini-Filho, MA; Costa, R; Jorge, R; Katayama, BY; Martin, LF; Messias, AM; Paula, JS, 2014)
"To determine the effect of oral acetazolamide on lowering the peak and duration of intraocular pressure (IOP) rise in glaucoma and glaucoma suspect patients, following intravitreal injection of ranibizumab for neovascular age-related macular degeneration."5.19Short-term intraocular pressure trends following intravitreal ranibizumab injections for neovascular age-related macular degeneration-the role of oral acetazolamide in protecting glaucoma patients. ( Allgar, V; Gale, RP; Murray, CD; Walters, G; Wood, D, 2014)
"05 mL of bevacizumab or ranibizumab), that were divided into five groups, group 1: no intraocular pressure (IOP)-lowering medication (n=50); group 2: apraclonidine 1 % one drop 2 hours prior to IVI (n=50); group 3: acetazolamide 250 mg 2 hours prior (n=50); group 4: fixed combination brimonidine+timolol (n=30); group 5: fixed combination dorzolamide+timolol (n=30)."5.16[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections]. ( Dot, C; El Chehab, H; Giraud, JM; Le Corre, A; Ract-Madoux, G; Swalduz, B, 2012)
"5% in preventing intraocular pressure (IOP) peaks during the early period after phacoemulsification in which sodium chondroitin sulfate 4%-sodium hyaluronate 3% (Viscoat) was used as the ophthalmic viscosurgical device (OVD)."5.12Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat. ( Akman, A; Akova, YA; Borazan, M; Karalezli, A, 2007)
"In 30 patients with ocular hypertension, aqueous flow and intraocular pressure (IOP) were determined at baseline and on the following combinations of drugs in a crossover design: (1) vehicle alone, (2) dorzolamide alone, (3) acetazolamide alone, (4) timolol alone, (5) dorzolamide + acetazolamide, and (6) dorzolamide + timolol."5.11Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide. ( Camras, CB; Toris, CB; Yablonski, ME; Zhan, GL, 2004)
"To assess the effect of intraoperative acetazolamide (Diamox) on postoperative intraocular pressure (IOP) in gas-filled, vitrectomized eyes."5.09Intraoperative acetazolamide in the prevention of intraocular pressure rise after pars plana vitrectomy with fluid-gas exchange. ( Grand, MG; Ruby, AJ; Thomas, MA; Williams, D, 1999)
"Prophylactic use of timolol gel for viscoelastic-induced ocular hypertension after PK appears to offer better IOP control than oral acetazolamide, with potentially fewer adverse systemic effects."5.08Comparison of topical timolol gel to oral acetazolamide in the prophylaxis of viscoelastic-induced ocular hypertension after penetrating keratoplasty. ( Donnenfeld, ED; Kanellopoulos, AJ; Perry, HD, 1997)
"0% dorzolamide hydrochloride with oral acetazolamide in preventing intraocular pressure (IOP) rise following neodymium:YAG (Nd:YAG) laser posterior capsulotomy."5.08Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy. ( Baltatzis, S; Kokolakis, SN; Ladas, ID; Panagiotidis, D; Theodossiadis, GP; Zafirakis, P, 1997)
"To compare postoperative intraocular pressure (IOP) after administration of acetazolamide and timolol following phacoemulsification and intraocular lens implantation."5.08Timolol gel versus acetazolamide in the prophylaxis of ocular hypertension after phacoemulsification. ( Donnenfeld, ED; Kanellopoulos, AJ; Perry, HD, 1997)
"The study aimed to determine whether topical dorzolamide and systemic acetazolamide have an additive effect on intraocular pressure (IOP) and aqueous humor formation (AHF)."5.08Combination of systemic acetazolamide and topical dorzolamide in reducing intraocular pressure and aqueous humor formation. ( Hong, PH; Krupin, T; Rosenberg, LF; Ruderman, JM; Tang, LQ, 1998)
"The aim of this study was to evaluate the effectiveness of topical dorzolamide versus systemic acetazolamide in preventing the intraocular pressure (IOP) spike, following routine phacoemulsification surgery."5.08A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification surgery. ( Lukaris, A; Roberts-Harry, TJ; Rogers, ZA; Sells, M; Zohdy, GA, 1998)
"Following a timolol and acetazolamide run-in, 105 patients with elevated intraocular pressure (IOP) were randomized to dorzolamide or acetazolamide, in addition to timolol, for 12 weeks."5.08A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group. ( Adamsons, IA; Hutzelmann, JE; Michael, AJ; Polis, AB, 1998)
"To investigate the additive ocular hypotensive effect of latanoprost on the intraocular pressure (IOP) reduction induced by a suboptimal dose of acetazolamide, a carbonic anhydrase inhibitor."5.08Additive ocular hypotensive effect of latanoprost and acetazolamide. A short-term study in patients with elevated intraocular pressure. ( Greve, EL; Hoyng, PF; Rulo, AH, 1997)
"This prospective study was done to compare the efficacy of timolol and acetazolamide in lowering the intraocular pressure (IOP) secondary to the use of sodium hyaluronate (Healon) in cataract surgery."5.07Effect of timolol vs. acetazolamide on sodium hyaluronate-induced rise in intraocular pressure after cataract surgery. ( Duperré, J; Grenier, B; Lambert, J; Lemire, J; Mihalovits, H; Sebag, M, 1994)
"The IOP 1-day postoperatively was analysed against the last recorded IOP before phacoemulsification in a cohort of patients with glaucoma or OHT who underwent uncomplicated phacoemulsification cataract surgery between December 2009 and September 2012, where it was routine practice to give acetazolamide postoperatively."3.81Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension? ( Gupta, A; Vernon, SA, 2015)
"To present the case of a 28-year-old man with acetazolamide-induced bilateral choroidal effusion after uneventful surgery of the second eye in delayed sequential bilateral insertion of an implantable collamer lens for hyperopia."3.79Acetazolamide-induced bilateral choroidal effusion following insertion of a phakic implantable collamer lens. ( Baviera, J; de Rojas, V; González-López, F, 2013)
" The use of systemic acetazolamide provided significant control of IOP and could be considered a 'possible standard' management of cataract surgery in POAG patients."3.78Short-term changes in intraocular pressure after phacoemulsification in glaucoma patients. ( Centofanti, M; Digiuni, M; Fea, A; Figus, M; Fogagnolo, P; Frezzotti, P; Lembo, A; Ligorio, P; Lorenzi, U; Rossetti, L, 2012)
" In an animal model of ocular hypertension, one of the new compounds was twice more effective than dorzolamide in reducing elevated intraocular pressure characteristic of this disease, anticipating their potential for the treatment of glaucoma."3.77Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. ( Benedini, F; Biondi, S; Cecchi, A; Formicola, G; Masini, E; Mincione, F; Pacileo, I; Scozzafava, A; Supuran, CT; Temperini, C, 2011)
"Acetazolamide's usefulness in the treatment of the glaucomas is limited by the systemic side effects that often accompany its oral administration, and topical administration was initially thought to have no effect upon the intraocular pressures of human and rabbit eyes."3.67Local ocular hypotensive effect of topically applied acetazolamide. ( Flach, AJ; Peterson, JS; Seligmann, KA, 1984)
"A patient with ocular hypertension was treated with acetazolamide."3.67Tamm-Horsfall protein accumulation in glomeruli during acetazolamide-induced acute renal failure. ( Jondeau, G; Kanfer, A; Mougenot, B; Ronco, P; Rondeau, E; Rossert, J; Sraer, JD, 1989)
"Intraocular pressure was measured preoperatively and 4 to 6 and 24 hours postoperatively."2.69Medical control of intraocular pressure after cataract surgery. ( Byrd, S; Singh, K, 1998)
"Rapid progression was observed from ocular hypertension to uveitic glaucoma."1.72High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis. ( Bennett, S; Chew, S; Ma, T; Niederer, RL; Sims, JL, 2022)
"Iris metastases were treated with 40 Gray of radiation therapy and concurrent chemotherapy."1.62Iris metastasis as the initial presentation of metastatic esophageal cancer diagnosed by fine needle aspiration biopsy: A case report. ( Horiuchi, N; Kuribayashi, T; Kurihara, T; Ozawa, H; Smith, LEH; Takano, Y; Tomita, Y; Tsubota, K; Usui, Y, 2021)
"Eight monkeys with untreated intraocular pressures (IOPs) of less than 18 mmHg in one eye (ONT group) and seven with untreated IOPs of greater than or equal to 18 mmHg in one eye (OHT group) were included in the study."1.36Aqueous humor dynamics in inbred rhesus monkeys with naturally occurring ocular hypertension. ( Dawson, WW; Gonzales-Martinez, J; McLaughlin, MA; Risma, JM; Toris, CB, 2010)
"Fifty-four eyes of 45 patients with ocular hypertension developed early glaucomatous optic disc or visual field changes after a mean follow-up of 5."1.29Visual field prognosis in early glaucoma. A long-term clinical follow-up. ( Odberg, T, 1993)
"Such an agent would be useful in the treatment of glaucoma."1.28Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity. ( Anderson, PS; Baldwin, JJ; Best, DB; Christy, ME; Freedman, MB; Gautheron, P; Graham, SL; Habecker, CN; Hoffman, JM; Shepard, KL, 1989)
"The ischemia was induced by elevating intraocular pressure; retinal and RPE function were monitored by electrophysiologic recordings."1.28Recovery of retinal pigment epithelial function after ischemia in the rabbit. ( Heike, M; Marmor, MF, 1991)
"Acetazolamide was capable of preventing the excessive IOP rise during dialysis."1.28Intraocular pressure changes during hemodialysis: prevention of excessive dialytic rise and development of severe metabolic acidosis following acetazolamide therapy. ( Cecchin, E; De Marchi, S; Tesio, F, 1989)
"Methylcellulose has been used since 1976 to prevent damage to the corneal endothelium during operations for implantation of intraocular lenses."1.27Methylcellulose, a viscous cushioning material in ophthalmic surgery. ( Fechner, PU, 1983)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199010 (14.49)18.7374
1990's24 (34.78)18.2507
2000's13 (18.84)29.6817
2010's20 (28.99)24.3611
2020's2 (2.90)2.80

Authors

AuthorsStudies
Graham, SL1
Shepard, KL1
Anderson, PS1
Baldwin, JJ1
Best, DB1
Christy, ME1
Freedman, MB1
Gautheron, P1
Habecker, CN1
Hoffman, JM1
Mincione, F1
Benedini, F1
Biondi, S1
Cecchi, A1
Temperini, C1
Formicola, G1
Pacileo, I1
Scozzafava, A2
Masini, E2
Supuran, CT2
Ferraroni, M1
Lucarini, L1
Korsakov, M1
Krasavin, M1
Ma, T1
Sims, JL1
Bennett, S1
Chew, S1
Niederer, RL1
Ozawa, H1
Usui, Y1
Takano, Y1
Horiuchi, N1
Kuribayashi, T1
Kurihara, T1
Smith, LEH1
Tsubota, K1
Tomita, Y1
Hayashi, K2
Yoshida, M2
Sato, T1
Manabe, SI2
Yoshimura, K2
Babiker, S1
Elsayed, ME1
Dhaygude, A1
Madgula, I1
Katayama, BY1
Bonini-Filho, MA1
Messias, AM1
Paula, JS1
Martin, LF1
Costa, R1
Jorge, R1
de Rojas, V1
González-López, F1
Baviera, J1
Karaśkiewicz, J1
Lubiński, W1
Penkala, K1
Gharbiya, M1
Colica, C1
Campagna, O1
De Vico, U1
Cruciani, F1
Murray, CD1
Wood, D1
Allgar, V1
Walters, G1
Gale, RP1
Gupta, A1
Vernon, SA1
Holtmann, C1
Spaniol, K1
Geerling, G1
Dot, C2
El Chehab, H2
Russo, A1
Agard, E1
Unlu, M1
Hondur, AM1
Korkmaz, S1
Kumova, D1
Yuksel, E1
Lorenz, K1
Wasielica-Poslednik, J1
Bell, K1
Renieri, G1
Keicher, A1
Ruckes, C1
Pfeiffer, N1
Thieme, H1
Li Yim, JF1
Ross, JZ1
Jay, JL1
Toris, CB2
Risma, JM1
Gonzales-Martinez, J1
McLaughlin, MA1
Dawson, WW1
Murakami, J1
Kim, A1
Sugiyama, T1
Inoue, K1
Matsumoto, C1
Shimomura, Y1
Fogagnolo, P1
Centofanti, M1
Figus, M1
Frezzotti, P1
Fea, A1
Ligorio, P1
Lembo, A1
Digiuni, M1
Lorenzi, U1
Rossetti, L1
Le Corre, A1
Giraud, JM1
Ract-Madoux, G1
Swalduz, B1
KLEINERT, H1
RADOVANOVIC, M1
YANKELEVICH, IJ1
Zhan, GL1
Yablonski, ME1
Camras, CB1
Viestenz, A1
Martus, P2
Schlötzer-Schrehardt, U1
Langenbucher, A1
Mardin, CY1
Călugăru, M1
Călugăru, D1
Kurian, M1
Shetty, R1
Shetty, BK1
Devi, SA1
Scuderi, G1
Regine, F1
Perdicchi, A1
Mannino, G1
Recupero, SM1
Dada, T1
Muralidhar, R1
Jhanji, V1
Borazan, M1
Karalezli, A1
Akman, A1
Akova, YA1
Smith, JP1
Weeks, RH1
Newland, EF1
Ward, RL1
Fechner, PU1
Flach, AJ1
Peterson, JS1
Seligmann, KA1
Feist, RM1
Palmer, DJ1
Fiscella, R1
Ernest, JT1
Tripathi, R1
Torczynski, E1
Farber, M1
John, M1
Souchek, J1
Noblitt, RL1
Boleyn, KL1
Davis, LC1
Bömer, TG1
Lagrèze, WD1
Funk, J1
Duperré, J1
Grenier, B1
Lemire, J1
Mihalovits, H1
Sebag, M1
Lambert, J1
Odberg, T1
Ladas, ID2
Pavlopoulos, GP1
Kokolakis, SN2
Theodossiadis, GP2
Barak, A1
Desatnik, H1
Ma-Naim, T1
Ashkenasi, I1
Neufeld, A1
Melamed, S1
Edmunds, B1
Canning, CR1
Whitefield, L1
Crowston, J1
Little, BC1
Kanellopoulos, AJ2
Perry, HD2
Donnenfeld, ED2
Rulo, AH1
Greve, EL1
Hoyng, PF1
Baltatzis, S1
Panagiotidis, D1
Zafirakis, P1
Kondo, T1
Miyazawa, D1
Unigame, K1
Kurimoto, Y1
Rosenberg, LF1
Krupin, T1
Tang, LQ1
Hong, PH1
Ruderman, JM1
Zohdy, GA1
Rogers, ZA1
Lukaris, A1
Sells, M1
Roberts-Harry, TJ1
Byrd, S1
Singh, K1
Hutzelmann, JE1
Polis, AB1
Michael, AJ1
Adamsons, IA1
Fichman, RA1
Ruby, AJ1
Grand, MG1
Williams, D1
Thomas, MA1
Chakraborty, P1
Villada, JR1
Tinu, A1
Ogawa, T1
Kitaoka, T1
Mera, A1
Saitoh, AK1
Amemiya, T1
Gottanka, J1
Johnson, DH1
Lütjen-Drecoll, E1
Parek, JG1
Raviv, T1
Speaker, MG1
Hitchings, R1
Stewart, WC1
Halper, LK1
Johnson-Pratt, L1
Polis, A1
Hartenbaum, D1
Fry, LL1
West, J1
Burke, J1
Cunliffe, I1
Longstaff, S1
Rohrschneider, K1
Koch, HR1
Heike, M1
Marmor, MF1
De Marchi, S1
Cecchin, E1
Tesio, F1
Rossert, J1
Rondeau, E1
Jondeau, G1
Ronco, P1
Mougenot, B1
Kanfer, A1
Sraer, JD1
Stilma, JS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Aqueous Humour Release (Burping) Performed at the Slit-lamp to Treat Acute Intraocular Pressure (IOP) Spikes Post-cataract Surgery[NCT03500809]20 participants (Anticipated)Interventional2018-08-12Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for acetazolamide and Glaucoma, Suspect

ArticleYear
Electrophysiological tests in evaluation of glaucoma and ocular hypertension treatment--up to date knowledge. A review.
    Klinika oczna, 2013, Volume: 115, Issue:2

    Topics: Acetazolamide; Dose-Response Relationship, Drug; Electroretinography; Glaucoma; Humans; Intraocular

2013
[Ocular hypertension after intravitreal steroid injections: Clinical update as of 2015].
    Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:7

    Topics: Acetazolamide; Adrenal Cortex Hormones; Adult; Animals; Child; Delayed-Action Preparations; Dexameth

2015
[Latanoprost topical ophthalmic combinations].
    Oftalmologia (Bucharest, Romania : 1990), 2004, Volume: 48, Issue:4

    Topics: Acetazolamide; Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Dinoprost; Dr

2004
Anesthesia and preoperative and postoperative medications.
    Current opinion in ophthalmology, 1996, Volume: 7, Issue:1

    Topics: Acetazolamide; Adrenergic beta-Antagonists; Anesthesia, Local; Anesthetics, Local; Anti-Bacterial Ag

1996

Trials

30 trials available for acetazolamide and Glaucoma, Suspect

ArticleYear
Intraocular pressure elevation after cataract surgery and its prevention by oral acetazolamide in eyes with pseudoexfoliation syndrome.
    Journal of cataract and refractive surgery, 2018, Volume: 44, Issue:2

    Topics: Acetazolamide; Administration, Oral; Aged; Carbonic Anhydrase Inhibitors; Exfoliation Syndrome; Fema

2018
Comparison of acetazolamide, brimonidine, and anterior chamber paracentesis for ocular hypertension control after initial intravitreal bevacizumab injection: a randomized clinical trial.
    Journal of glaucoma, 2014, Volume: 23, Issue:7

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Aged; Angiogenesis Inhibitors; Anterio

2014
Short-term intraocular pressure trends following intravitreal ranibizumab injections for neovascular age-related macular degeneration-the role of oral acetazolamide in protecting glaucoma patients.
    Eye (London, England), 2014, Volume: 28, Issue:10

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, M

2014
Prophylactic Effect of Oral Acetazolamide against Intraocular Pressure Elevation after Cataract Surgery in Eyes with Glaucoma.
    Ophthalmology, 2017, Volume: 124, Issue:5

    Topics: Acetazolamide; Administration, Oral; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors;

2017
Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Acetazolamide; Aged; Antihypertensive Agents; Dexamethasone; Drug Combinations; Female; Fluorouracil

2017
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
    Journal francais d'ophtalmologie, 2012, Volume: 35, Issue:8

    Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimon

2012
Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide.
    Journal of glaucoma, 2004, Volume: 13, Issue:3

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Antihypertensive Agents;

2004
[Impact of prostaglandin-F(2alpha)-analogues and carbonic anhydrase inhibitors on central corneal thickness -- a cross-sectional study on 403 eyes].
    Klinische Monatsblatter fur Augenheilkunde, 2004, Volume: 221, Issue:9

    Topics: Acetazolamide; Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Co

2004
Comparative efficacy of acetazolamide and apraclonidine in the control of intraocular pressure following phacoemulsification.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2006, Volume: 220, Issue:6

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Aged; Aged,

2006
Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:11

    Topics: Acetazolamide; Acetylcholine; Administration, Topical; Aged; Aged, 80 and over; Antihypertensive Age

2007
Betaxolol and acetazolamide. Combined ocular hypotensive effect.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:12

    Topics: Acetazolamide; Administration, Oral; Adult; Aged; Aqueous Humor; Betaxolol; Clinical Trials as Topic

1984
Effectiveness of apraclonidine and acetazolamide in preventing postoperative intraocular pressure spikes after extracapsular cataract extraction.
    Journal of cataract and refractive surgery, 1995, Volume: 21, Issue:2

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Aged; Catar

1995
Sideport incision paracentesis versus antiglaucoma medication to control postoperative pressure rises after intraocular lens surgery.
    Journal of cataract and refractive surgery, 1993, Volume: 19, Issue:1

    Topics: Acetazolamide; Aged; Aqueous Humor; Cataract Extraction; Drainage; Female; Humans; Intraocular Press

1993
[Increased intraocular pressure after cataract extraction--effect of surgical technique, surgical procedure and preventive drug administration. A prospective, randomized double-blind study].
    Klinische Monatsblatter fur Augenheilkunde, 1995, Volume: 206, Issue:1

    Topics: Acetazolamide; Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Cataract Extraction; Clinical Com

1995
Effect of timolol vs. acetazolamide on sodium hyaluronate-induced rise in intraocular pressure after cataract surgery.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1994, Volume: 29, Issue:4

    Topics: Acetazolamide; Administration, Oral; Adult; Aged; Aged, 80 and over; Cataract Extraction; Female; Hu

1994
Prophylactic use of acetazolamide to prevent intraocular pressure elevation following Nd-YAG laser posterior capsulotomy.
    The British journal of ophthalmology, 1993, Volume: 77, Issue:3

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; L

1993
Early postoperative intraocular pressure pattern in glaucomatous and nonglaucomatous patients.
    Journal of cataract and refractive surgery, 1996, Volume: 22, Issue:5

    Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibi

1996
The effect of prophylactic acetazolamide in patients undergoing extensive retinal detachment repair.
    Eye (London, England), 1996, Volume: 10 ( Pt 3)

    Topics: Acetazolamide; Female; Humans; Intraocular Pressure; Length of Stay; Male; Middle Aged; Ocular Hyper

1996
Comparison of topical timolol gel to oral acetazolamide in the prophylaxis of viscoelastic-induced ocular hypertension after penetrating keratoplasty.
    Cornea, 1997, Volume: 16, Issue:1

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Carbonic

1997
Additive ocular hypotensive effect of latanoprost and acetazolamide. A short-term study in patients with elevated intraocular pressure.
    Ophthalmology, 1997, Volume: 104, Issue:9

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; C

1997
Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:10

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhy

1997
Timolol gel versus acetazolamide in the prophylaxis of ocular hypertension after phacoemulsification.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:7

    Topics: Acetazolamide; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Delayed-Action Preparatio

1997
Combination of systemic acetazolamide and topical dorzolamide in reducing intraocular pressure and aqueous humor formation.
    Ophthalmology, 1998, Volume: 105, Issue:1

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydra

1998
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification surgery.
    Journal of the Royal College of Surgeons of Edinburgh, 1998, Volume: 43, Issue:5

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female;

1998
Medical control of intraocular pressure after cataract surgery.
    Journal of cataract and refractive surgery, 1998, Volume: 24, Issue:11

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Aged; Carbo

1998
A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:6

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Ag

1998
Intraoperative acetazolamide in the prevention of intraocular pressure rise after pars plana vitrectomy with fluid-gas exchange.
    Retina (Philadelphia, Pa.), 1999, Volume: 19, Issue:3

    Topics: Acetazolamide; Ciliary Body; Gases; Humans; Injections, Intravenous; Intraocular Pressure; Intraoper

1999
Tolerability and efficacy of dorzolamide versus acetazolamide added to timolol.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:3

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbon

2002
Comparison of the postoperative intraocular pressure with Betagan, Betoptic, Timoptic, Iopidine, Diamox, Pilopine Gel, and Miostat.
    Journal of cataract and refractive surgery, 1992, Volume: 18, Issue:1

    Topics: Acetazolamide; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Cata

1992
Prevention of acute postoperative pressure rises in glaucoma patients undergoing cataract extraction with posterior chamber lens implant.
    The British journal of ophthalmology, 1992, Volume: 76, Issue:9

    Topics: Acetazolamide; Acetylcholine; Acute Disease; Aged; Aged, 80 and over; Cataract Extraction; Drug Ther

1992

Other Studies

35 other studies available for acetazolamide and Glaucoma, Suspect

ArticleYear
Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:12

    Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Glaucoma; Guinea Pigs; Intrao

1989
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.
    Bioorganic & medicinal chemistry letters, 2011, Jun-01, Volume: 21, Issue:11

    Topics: Animals; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Disease Models, Animal; Glaucoma; Hu

2011
1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads.
    Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

    Topics: Animals; Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray

2017
High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis.
    The British journal of ophthalmology, 2022, Volume: 106, Issue:11

    Topics: Acetazolamide; Female; Glaucoma; HLA-B27 Antigen; Humans; Male; Middle Aged; Ocular Hypertension; Uv

2022
Iris metastasis as the initial presentation of metastatic esophageal cancer diagnosed by fine needle aspiration biopsy: A case report.
    Medicine, 2021, Jun-04, Volume: 100, Issue:22

    Topics: Acetazolamide; Administration, Oral; Aged; Anterior Chamber; Biopsy, Fine-Needle; Carbonic Anhydrase

2021
A complex case of haemodialysis induced increased intraocular pressure.
    European journal of ophthalmology, 2019, Volume: 29, Issue:1_suppl

    Topics: Acetazolamide; Antihypertensive Agents; Diabetes Mellitus, Type 1; Glaucoma, Neovascular; Humans; In

2019
Acetazolamide-induced bilateral choroidal effusion following insertion of a phakic implantable collamer lens.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2013, Volume: 29, Issue:8

    Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Choroid; Choroid Diseases

2013
Urrets- Zavalia Syndrome after glaucoma filtration device implantation.
    La Clinica terapeutica, 2013, Volume: 164, Issue:5

    Topics: Acetazolamide; Aged; Brimonidine Tartrate; Cataract Extraction; Combined Modality Therapy; Drug Resi

2013
Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension?
    Eye (London, England), 2015, Volume: 29, Issue:10

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract; Female; Glau

2015
Urrets-Zavalia syndrome after Descemet membrane endothelial keratoplasty.
    European journal of ophthalmology, 2015, Jul-30, Volume: 25, Issue:5

    Topics: Acetazolamide; Aged; Cataract Extraction; Combined Modality Therapy; Descemet Stripping Endothelial

2015
Pharmacologic Management of Pressure-Induced Stromal Keratopathy after LASIK.
    Optometry and vision science : official publication of the American Academy of Optometry, 2016, Volume: 93, Issue:7

    Topics: Acetazolamide; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Brimonidine

2016
Pupil block following inadvertent back to front implantation of a 5 degrees vaulted posterior chamber intraocular lens.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2010, Volume: 45, Issue:3

    Topics: Acetazolamide; Aged; Cyclopentolate; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocula

2010
Aqueous humor dynamics in inbred rhesus monkeys with naturally occurring ocular hypertension.
    Experimental eye research, 2010, Volume: 91, Issue:6

    Topics: Acetazolamide; Animals; Animals, Inbred Strains; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cilia

2010
A case of ocular hypertension complicated by SUNCT syndrome.
    Annals of ophthalmology (Skokie, Ill.), 2010, Volume: 42 Spec No

    Topics: Acetazolamide; Amlodipine; Carbamazepine; Drug Therapy, Combination; Female; Humans; Intraocular Pre

2010
Short-term changes in intraocular pressure after phacoemulsification in glaucoma patients.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2012, Volume: 228, Issue:3

    Topics: Acetazolamide; Administration, Oral; Aged; Carbonic Anhydrase Inhibitors; Cataract; Glaucoma, Open-A

2012
[The effect of a new diuretic, diamox, on pathological ocular hypertension].
    Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung, 1954, Volume: 125, Issue:3

    Topics: Acetazolamide; Diuretics; Glaucoma; Hydro-Lyases; Ocular Hypertension

1954
[Effect of diamox on eye hypertension].
    Vojnosanitetski pregled, 1957, Volume: 14, Issue:5

    Topics: Acetazolamide; Aged; Glaucoma; Humans; Hypertension; Ocular Hypertension

1957
[Medical treatment of acute ocular hypertension].
    Archivos de oftalmologia de Buenos Aires, 1961, Volume: 36

    Topics: Acetazolamide; Eye Diseases; Glucose; Humans; Intraocular Pressure; Ocular Hypertension; Pilocarpine

1961
In vivo confocal microscopic findings of interlamellar stromal keratopathy induced by elevated intraocular pressure.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:9

    Topics: Acetazolamide; Adult; Antihypertensive Agents; Corneal Diseases; Corneal Stroma; Drug Therapy, Combi

2006
Intraocular pressure rise after use of Healon 5 during extracapsular cataract surgery.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2

    Topics: Acetazolamide; Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Humans; Hyaluronic Acid; In

2007
Methylcellulose, a viscous cushioning material in ophthalmic surgery.
    Transactions of the ophthalmological societies of the United Kingdom, 1983, Volume: 103 ( Pt 3)

    Topics: Acetazolamide; Eye; Humans; Lenses, Intraocular; Methods; Methylcellulose; Ocular Hypertension

1983
Local ocular hypotensive effect of topically applied acetazolamide.
    American journal of ophthalmology, 1984, Jul-15, Volume: 98, Issue:1

    Topics: Acetazolamide; Administration, Topical; Animals; Injections, Intravenous; Intraocular Pressure; Male

1984
Visual field prognosis in early glaucoma. A long-term clinical follow-up.
    Acta ophthalmologica, 1993, Volume: 71, Issue:6

    Topics: Acetazolamide; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal S

1993
First day follow up for routine phacoemulsification?
    The British journal of ophthalmology, 1996, Volume: 80, Issue:2

    Topics: Acetazolamide; Humans; Lenses, Intraocular; Ocular Hypertension; Phacoemulsification; Postoperative

1996
Ultrasound biomicroscopic findings in humans with shallow anterior chamber and increased intraocular pressure after the prone provocation test.
    American journal of ophthalmology, 1997, Volume: 124, Issue:5

    Topics: Acetazolamide; Administration, Oral; Aged; Anterior Chamber; Carbonic Anhydrase Inhibitors; Diagnost

1997
Medical control of IOP after cataract surgery.
    Journal of cataract and refractive surgery, 2000, Volume: 26, Issue:2

    Topics: Acetazolamide; Adrenergic alpha-Agonists; Carbonic Anhydrase Inhibitors; Clonidine; Drug Therapy, Co

2000
Treatment for subretinal hemorrhage in the macula: pneumatic displacement of hemorrhages.
    Retina (Philadelphia, Pa.), 2000, Volume: 20, Issue:6

    Topics: Acetazolamide; Aged; Aged, 80 and over; Female; Fundus Oculi; Humans; Injections; Intraocular Pressu

2000
Beta-adrenergic blocker therapy and the trabecular meshwork.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2001, Volume: 239, Issue:2

    Topics: Acetazolamide; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aqueous Humor; Drug Therapy, Co

2001
Grossly false applanation tonometry associated with interface fluid in susceptible LASIK patients.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:8

    Topics: Acetazolamide; Adult; Body Fluids; Carbonic Anhydrase Inhibitors; Diagnostic Errors; Humans; Intraoc

2001
Traumatic glaucoma.
    Journal of glaucoma, 2001, Volume: 10, Issue:5

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cataract; Eye Injuries; Glaucoma; Golf; Humans;

2001
[Effects of acetazolamide (Diamox, Glaupax) on tear production].
    Klinische Monatsblatter fur Augenheilkunde, 1991, Volume: 199, Issue:2

    Topics: Acetazolamide; Aged; Cataract Extraction; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ocul

1991
Recovery of retinal pigment epithelial function after ischemia in the rabbit.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:1

    Topics: Acetazolamide; Animals; Choroid; Dark Adaptation; Disease Models, Animal; Electroretinography; Intra

1991
Intraocular pressure changes during hemodialysis: prevention of excessive dialytic rise and development of severe metabolic acidosis following acetazolamide therapy.
    Renal failure, 1989, Volume: 11, Issue:2-3

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Adult; Aged; Female; Gonioscopy; Humans; Intraocular

1989
Tamm-Horsfall protein accumulation in glomeruli during acetazolamide-induced acute renal failure.
    American journal of nephrology, 1989, Volume: 9, Issue:1

    Topics: Acetazolamide; Acute Kidney Injury; Fluorescent Antibody Technique; Humans; Kidney Glomerulus; Male;

1989
Prevention of intra-ocular pressure elevation following laser surgery.
    Bulletin de la Societe belge d'ophtalmologie, 1986, Volume: 220

    Topics: Acetazolamide; Drug Therapy, Combination; Humans; Laser Therapy; Ocular Hypertension; Timolol

1986