acetazolamide has been researched along with Genetic Predisposition in 11 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide has been the most commonly used treatment for hypokalemic periodic paralysis since 1968." | 7.77 | Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype. ( Davis, MB; Griggs, RC; Hanna, MG; Haworth, A; Ke, Q; Matthews, E; Portaro, S; Sud, R, 2011) |
| "A continuing survey of the genetic variability of different mouse strains to acetazolamide teratogenesis demonstrated the WB/ReJ strain expresses a high frequency of induced subcutaneous edema in day 15 fetuses." | 7.68 | Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide. ( Biddle, FG, 1990) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but fatal adverse mucocutaneous reactions to certain drugs." | 5.42 | Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine. ( Kim, SR; Koh, BS; Lee, JH; Leem, DW; Moon, IJ; Park, HJ; Park, JW; Park, KH, 2015) |
| "Acetazolamide has been the most commonly used treatment for hypokalemic periodic paralysis since 1968." | 3.77 | Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype. ( Davis, MB; Griggs, RC; Hanna, MG; Haworth, A; Ke, Q; Matthews, E; Portaro, S; Sud, R, 2011) |
| "A continuing survey of the genetic variability of different mouse strains to acetazolamide teratogenesis demonstrated the WB/ReJ strain expresses a high frequency of induced subcutaneous edema in day 15 fetuses." | 3.68 | Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide. ( Biddle, FG, 1990) |
| "Meniere's disease is a clinical syndrome of uncertain aetiology but it is a widespread belief that it is related to endolymphatic hydrops." | 2.43 | Hypothesis: could Meniere's disease be a channelopathy? ( Gates, P, 2005) |
| "Acetazolamide was administered to 6 dogs, and 4 dogs experienced a decrease in episode frequency." | 1.56 | Phenotypic characterization of paroxysmal dyskinesia in Maltese dogs. ( Bhatti, SFM; Broeckx, BJG; Charalambous, M; Cornelis, I; Polidoro, D; Santens, P; Van Ham, L, 2020) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but fatal adverse mucocutaneous reactions to certain drugs." | 1.42 | Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine. ( Kim, SR; Koh, BS; Lee, JH; Leem, DW; Moon, IJ; Park, HJ; Park, JW; Park, KH, 2015) |
| "We report a child with congenital ataxia, abnormal eye movements and developmental delay who presented severe attacks of hemiplegic migraine triggered by minor head traumas and associated with hemispheric swelling and seizures." | 1.40 | Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A. ( Al-Qusairi, L; Bonafé, L; García Segarra, N; Gautschi, I; Kallay Zetchi, C; Maeder, P; Mittaz-Crettol, L; Roulet-Perez, E; Schild, L; Van Bemmelen, MX, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Ketz, J | 1 |
| Saxena, V | 1 |
| Arregui, S | 1 |
| Jackson, A | 1 |
| Schwartz, GJ | 1 |
| Yagisawa, T | 1 |
| Fairchild, RL | 1 |
| Hains, DS | 1 |
| Schwaderer, AL | 1 |
| Polidoro, D | 1 |
| Van Ham, L | 1 |
| Santens, P | 1 |
| Cornelis, I | 1 |
| Charalambous, M | 1 |
| Broeckx, BJG | 1 |
| Bhatti, SFM | 1 |
| García Segarra, N | 1 |
| Gautschi, I | 1 |
| Mittaz-Crettol, L | 1 |
| Kallay Zetchi, C | 1 |
| Al-Qusairi, L | 1 |
| Van Bemmelen, MX | 1 |
| Maeder, P | 1 |
| Bonafé, L | 1 |
| Schild, L | 1 |
| Roulet-Perez, E | 1 |
| Rodà, D | 1 |
| Fons-Estupiña, MC | 1 |
| Vidal-Santacana, M | 1 |
| Park, HJ | 1 |
| Kim, SR | 1 |
| Leem, DW | 1 |
| Moon, IJ | 1 |
| Koh, BS | 1 |
| Park, KH | 1 |
| Park, JW | 1 |
| Lee, JH | 1 |
| Tacik, P | 1 |
| Guthrie, KJ | 1 |
| Strongosky, AJ | 1 |
| Broderick, DF | 1 |
| Riegert-Johnson, DL | 1 |
| Tang, S | 1 |
| El-Khechen, D | 1 |
| Parker, AS | 1 |
| Ross, OA | 1 |
| Wszolek, ZK | 1 |
| Suyama, K | 1 |
| Yoshida, K | 1 |
| Hayashi, K | 1 |
| Takahata, H | 1 |
| Yonekura, M | 1 |
| Nagata, I | 1 |
| Matthews, E | 1 |
| Portaro, S | 1 |
| Ke, Q | 1 |
| Sud, R | 1 |
| Haworth, A | 1 |
| Davis, MB | 1 |
| Griggs, RC | 1 |
| Hanna, MG | 1 |
| Gates, P | 1 |
| Cricchi, F | 1 |
| Di Lorenzo, C | 1 |
| Grieco, GS | 1 |
| Rengo, C | 1 |
| Cardinale, A | 1 |
| Racaniello, M | 1 |
| Santorelli, FM | 1 |
| Nappi, G | 1 |
| Pierelli, F | 1 |
| Casali, C | 1 |
| Biddle, FG | 1 |
1 review available for acetazolamide and Genetic Predisposition
| Article | Year |
|---|---|
Hypothesis: could Meniere's disease be a channelopathy?
Topics: Acetazolamide; Adult; Aged; Disease Progression; Endolymphatic Hydrops; Female; Genetic Predispositi | 2005 |
10 other studies available for acetazolamide and Genetic Predisposition
| Article | Year |
|---|---|
Developmental loss, but not pharmacological suppression, of renal carbonic anhydrase 2 results in pyelonephritis susceptibility.
Topics: Acetazolamide; Acidosis; Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Disease Mode | 2020 |
Phenotypic characterization of paroxysmal dyskinesia in Maltese dogs.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Chorea; Diet, Gluten-Free; Dog Diseases; Dogs | 2020 |
Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A.
Topics: Acetazolamide; Adolescent; Animals; Ataxia; Brain Edema; Calcium Channels; Cerebellar Ataxia; Child; | 2014 |
[Familial idiopathic intracranial hypertension: two paediatric case reports].
Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Child; Female; Genetic Predisposition to D | 2014 |
Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine.
Topics: Acetaminophen; Acetazolamide; Adult; Aged; Aged, 80 and over; Alleles; Allopurinol; Anti-Bacterial A | 2015 |
Whole-exome sequencing as a diagnostic tool in a family with episodic ataxia type 1.
Topics: Acetazolamide; Anticonvulsants; Ataxia; Base Sequence; Electroencephalography; Electromyography; Exo | 2015 |
Coexistence of Chiari 2 malformation and moyamoya syndrome in a 17-year-old girl.
Topics: Acetazolamide; Adolescent; Agenesis of Corpus Callosum; Anastomosis, Surgical; Arnold-Chiari Malform | 2009 |
Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cohort Studies; Female; Genetic Predisposition to Dise | 2011 |
Early-onset progressive ataxia associated with the first CACNA1A mutation identified within the I-II loop.
Topics: Acetazolamide; Age of Onset; Amino Acid Substitution; Calcium Channels; Carbonic Anhydrase Inhibitor | 2007 |
Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide.
Topics: Acetazolamide; Animals; Crosses, Genetic; Edema; Female; Fetal Diseases; Genetic Predisposition to D | 1990 |