acetazolamide has been researched along with Gastric Ulcer in 29 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "An open-controlled trial performed in gastric ulcer cases resistant to previous cimetidine, antacids, vitamin A and polyvinylbutylether therapy applied for at least 4 weeks." | 9.06 | Successful treatment of intractable gastric ulcers with acetazolamide. ( Erdei, A; Gedeon, A; Gyóri, I; Szabó, I, 1990) |
| "An open-controlled trial performed in gastric ulcer cases resistant to previous cimetidine, antacids, vitamin A and polyvinylbutylether therapy applied for at least 4 weeks." | 5.06 | Successful treatment of intractable gastric ulcers with acetazolamide. ( Erdei, A; Gedeon, A; Gyóri, I; Szabó, I, 1990) |
| " Acetazolamide increased the gastric ulcerogenicity of indomethacin, but inhibited gastric ulcers produced by acidified aspirin." | 3.67 | Ulcer formation and cytoprotection by acetazolamide. ( Davis, JP; Kolbasa, KP; Lancaster, C; Nezamis, JE; Robert, A, 1985) |
| "Recognising the inhibitory activity of acetazolamide upon acid gastric secretion and its favorable effects in the treatment of gastric ulcer which we have described (see reference) - we applied the therapeutical testing by acetazolamide in the differentiation of benign from malignant niches of the stomach." | 3.65 | Therapeutic testing by acetazolamide in the differentiation of a benign from a malignant niche. ( Puscas, I; Resiga, C; Veress, S, 1977) |
| "Pretreatment with acetazolamide did not influence the protective action of PGE2 on ethanol-induced mucosal lesions and only slightly inhibited the protective effect of PGE2 on ASA-induced gastric ulcerations." | 1.27 | Gastric cytoprotection by acetazolamide: role of endogenous prostaglandins. ( Brzozowski, T; Konturek, SJ; Piastucki, I; Radecki, T, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (86.21) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 2 (6.90) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nishimori, I | 2 |
| Minakuchi, T | 2 |
| Morimoto, K | 1 |
| Sano, S | 1 |
| Onishi, S | 2 |
| Takeuchi, H | 2 |
| Vullo, D | 2 |
| Scozzafava, A | 2 |
| Supuran, CT | 2 |
| Kohsaki, T | 1 |
| MUELLER, WA | 1 |
| BRAUN, J | 1 |
| Kollberg, B | 1 |
| Aly, A | 1 |
| Rubio, C | 1 |
| Johansson, C | 1 |
| Barbarino, F | 1 |
| Togănel, E | 1 |
| Brilinschi, C | 1 |
| Kivilaakso, E | 4 |
| Cho, CH | 3 |
| Chen, SM | 1 |
| Chen, SW | 1 |
| Chow, CK | 1 |
| Lai, KH | 1 |
| Pfeiffer, CJ | 2 |
| Puşcaş, I | 6 |
| Konturek, SJ | 1 |
| Brzozowski, T | 1 |
| Piastucki, I | 1 |
| Radecki, T | 1 |
| Vălean, S | 1 |
| Vlaicu, R | 1 |
| Ionescu, I | 1 |
| Grigor'ev, PIa | 1 |
| Khar'kovskiĭ, NN | 1 |
| Iakovenko, EP | 1 |
| Elina, NA | 1 |
| Kashirina, LV | 1 |
| Starlinger, M | 1 |
| Jakesz, R | 1 |
| Matthews, JB | 1 |
| Yoon, C | 1 |
| Schiessel, R | 2 |
| Barzilai, A | 1 |
| Fromm, D | 1 |
| Silen, W | 2 |
| Gutierrez-Cabano, CA | 1 |
| Veress, S | 3 |
| Resiga, C | 3 |
| Paun, R | 1 |
| Ursea, N | 1 |
| Dragomir, N | 1 |
| Roscin, M | 1 |
| Erdei, A | 1 |
| Gyóri, I | 1 |
| Gedeon, A | 1 |
| Szabó, I | 1 |
| Hajdu, A | 1 |
| Buzás, G | 1 |
| Bernáth, Z | 1 |
| Ogle, CW | 1 |
| Li, HQ | 1 |
| Kawano, J | 1 |
| Sato, S | 1 |
| Kamata, T | 1 |
| Kumagai, J | 1 |
| Kaneko, E | 1 |
| Honda, N | 1 |
| Robert, A | 1 |
| Lancaster, C | 1 |
| Davis, JP | 1 |
| Kolbasa, KP | 1 |
| Nezamis, JE | 1 |
| Dobrescu, D | 2 |
4 trials available for acetazolamide and Gastric Ulcer
| Article | Year |
|---|---|
Treatment of gastroduodenal ulcers with carbonic anhydrase inhibitors.
Topics: Acetazolamide; Adolescent; Adult; Antacids; Anti-Ulcer Agents; Bicarbonates; Carbonic Anhydrase Inhi | 1984 |
[Letter: Difference between benign and cancerous gastric niches. Therapeutic test with acetazolamide].
Topics: Acetazolamide; Clinical Trials as Topic; Diagnosis, Differential; Humans; Radiography; Stomach Neopl | 1975 |
Successful treatment of intractable gastric ulcers with acetazolamide.
Topics: Acetazolamide; Cimetidine; Humans; Pain; Prospective Studies; Stomach Ulcer | 1990 |
Prevention of non-steroidal anti-inflammatory agents induced acute gastric mucosal lesions by carbonic anhydrase inhibitors. An endoscopic study.
Topics: Acetazolamide; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastroscopy; | 1989 |
25 other studies available for acetazolamide and Gastric Ulcer
| Article | Year |
|---|---|
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; DNA, Ba | 2006 |
Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chemistry, Pharmaceutical; | 2007 |
[THE DIFFERENT FORMS OF EXPERIMENTAL VENTRICULAR ULCER IN RATS AND THEIR MEDICAL CONTROL. 3. INDUCTION OF GASTRIC GLAND ULCERS IN RATS BY IMMOBILIZATION OF THE ANIMAL. OBSERVATION ON UROPEPSINOGEN EXCRETION AND ITS CONTROL BY DRUGS].
Topics: Acetazolamide; Animals; Bis-Trimethylammonium Compounds; Endopeptidases; Enzyme Precursors; Gastric | 1964 |
Acetazolamide interferes with the protective effect of prostaglandin E2 in the rat gastric mucosa.
Topics: Acetazolamide; Alkalies; Animals; Carbonic Anhydrase Inhibitors; Cyclooxygenase Inhibitors; Dinopros | 1981 |
The effects of acetazolamide and of ethoxzolamide on gastric microcirculation in rats (histochemical study).
Topics: Acetazolamide; Adenosine Triphosphatases; Animals; Ethoxzolamide; Female; Gastric Mucosa; Histocytoc | 1984 |
High plasma HCO3-protects gastric mucosa against acute ulceration in the rat.
Topics: Acetazolamide; Animals; Bicarbonates; Gastric Juice; Gastric Mucosa; Hydrogen-Ion Concentration; Rat | 1981 |
Pathogenesis of gastric ulceration produced by acetazolamide in rats.
Topics: Acetazolamide; Animals; Bicarbonates; Carbonic Anhydrase Inhibitors; Dinoprostone; Dose-Response Rel | 1984 |
Contribution of ambient HCO3- to mucosal protection and intracellular pH in isolated amphibian gastric mucosa.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Animals; Bicarbonates; Ca | 1983 |
Gastric cytoprotection by acetazolamide: role of endogenous prostaglandins.
Topics: Acetazolamide; Animals; Aspirin; Carbonic Anhydrases; Dinoprostone; Drug Evaluation; Ethanol; Female | 1983 |
Study of the damaging effects of acetazolamide on gastric mucosa in rats.
Topics: Acetazolamide; Animals; Anti-Ulcer Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose- | 1984 |
Treatment of gastric ulcer with carbonic anhydrase inhibitors.
Topics: Acetazolamide; Aged; Female; Humans; Male; Middle Aged; Pain; Radiography; Stomach Ulcer | 1984 |
[Treatment of peptic ulcer with ulcosilvanil].
Topics: Acetazolamide; Adult; Aged; Anti-Ulcer Agents; Bicarbonates; Drug Combinations; Duodenal Ulcer; Fema | 1984 |
[The protective effect of systemic HCO3- administration on the gastric mucosa in shock].
Topics: Acetazolamide; Acid-Base Equilibrium; Animals; Bicarbonates; Epoprostenol; Gastric Mucosa; Infusions | 1982 |
Experimental ulceration of rabbit antral mucosa.
Topics: Acetazolamide; Animals; Gastric Mucosa; Hydrogen; Hydrogen-Ion Concentration; Pepsin A; Pyloric Antr | 1981 |
The role of mucosal carbonic anhydrase in the protection of gastric mucosa against luminal H+.
Topics: Acetazolamide; Animals; Carbonic Anhydrases; Gastric Acid; Gastric Mucosa; Rabbits; Rana catesbeiana | 1981 |
Luminal acid in water-immersion stress and the antiulcer effect of axetazolamide in the rat gastric mucosa.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Female; Gastric Acid; Gastric Mucosa; Immersi | 1999 |
Therapeutic testing by acetazolamide in the differentiation of a benign from a malignant niche.
Topics: Acetazolamide; Diagnosis, Differential; Drug Evaluation; Humans; Stomach Neoplasms; Stomach Ulcer; T | 1977 |
[Carbonic anhydrase inhibitors in the treatment of gastric and duodenal ulcers (author's transl)].
Topics: Acetazolamide; Adult; Aged; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Stomach Ulcer | 1976 |
The possible role of metabolic acidosis in acetazolamide-induced gastric lesion formation in rats.
Topics: Acetazolamide; Acidosis; Animals; Bicarbonates; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred | 1989 |
[Effect of NaHCO3 infusion on the healing of acetic acid-induced gastric ulcer in rats].
Topics: Acetates; Acetazolamide; Acetic Acid; Animals; Bicarbonates; Infusions, Parenteral; Male; Rats; Rats | 1986 |
The role of carbonic anhydrase in gastric mucosal protection with special reference to H+ back diffusion and concomitant metabolic acidosis induced by acetazolamide.
Topics: Acetazolamide; Acidosis; Animals; Bicarbonates; Carbonic Anhydrases; Gastric Mucosa; Hydrogen-Ion Co | 1986 |
Ulcer formation and cytoprotection by acetazolamide.
Topics: 16,16-Dimethylprostaglandin E2; Acetazolamide; Animals; Aspirin; Dinoprostone; Ethanol; Female; Gast | 1985 |
[Action of acetazolamide on some experimental gastric ulcers].
Topics: Acetazolamide; Animals; Electric Stimulation; Guinea Pigs; Histamine; Male; Rats; Reserpine; Stomach | 1966 |
[Treatment of gastric ulcer with acetazolamide and the differentiation between benign and malignant niches].
Topics: Acetazolamide; Diagnosis, Differential; Gastric Juice; Humans; Phenylbutazone; Stomach Neoplasms; St | 1974 |
[Concerning the ulcerogenic action of phenylbutazone. Effect on it of carbonic anhydrase inhibiting substances].
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Phenylbutazone; Rats; Stomach Ulcer | 1965 |