acetazolamide has been researched along with Fetal Resorption in 4 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Fetal Resorption: The disintegration and assimilation of the dead FETUS in the UTERUS at any stage after the completion of organogenesis which, in humans, is after the 9th week of GESTATION. It does not include embryo resorption (see EMBRYO LOSS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide was administered orally by gavage to pregnant mice twice a day on days six through 15 of gestation at a dose level of 300." | 1.26 | Teratogenic activity in the mouse after oral administration of acetazolamide. ( Baldwin, JK; Sofia, RD; Tellone, CI, 1980) |
| "The frequency of hemimelia and micromelia, and of bilateral involvement, was greater in litters exposed to the high pH acetazolamide or the epinephrine-acetazolamide combinations, and was reduced by phentolamine or adrenal medullectomy." | 1.26 | Potentiation by the injection vehicle of the teratological action of acetazolamide in rats. ( Jones, JC; Muther, TF; Smoak, NS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dodo, T | 1 |
| Uchida, K | 1 |
| Hirose, T | 1 |
| Fukuta, T | 1 |
| Kojima, C | 1 |
| Shiraishi, I | 1 |
| Kato, E | 1 |
| Horiba, T | 1 |
| Mineshima, H | 1 |
| Okuda, Y | 1 |
| Maeda, M | 1 |
| Katsutani, N | 1 |
| Hirano, K | 1 |
| Aoki, T | 1 |
| Hackman, RM | 1 |
| Hurley, LS | 1 |
| Tellone, CI | 1 |
| Baldwin, JK | 1 |
| Sofia, RD | 1 |
| Muther, TF | 1 |
| Jones, JC | 1 |
| Smoak, NS | 1 |
4 other studies available for acetazolamide and Fetal Resorption
| Article | Year |
|---|---|
Increases in discontinuous rib cartilage and fused carpal bone in rat fetuses exposed to the teratogens, busulfan, acetazolamide, vitamin A, and ketoconazole.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Busulfan; Carpal Bones; Cartilage; Diterpenes; | 2010 |
Interaction of dietary zinc, genetic strain, and acetazolamide in teratogenesis in mice.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Diet; Female; Fetal Resorption; Mice; Mice, Inb | 1983 |
Teratogenic activity in the mouse after oral administration of acetazolamide.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Administration, Oral; Animals; Body Weight; Bone and Bon | 1980 |
Potentiation by the injection vehicle of the teratological action of acetazolamide in rats.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Adrenal Medulla; Animals; Drug Synergism; Ectromelia; Ep | 1977 |