Compounds > acetazolamide
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acetazolamide and Familial Periodic Paralysis

acetazolamide has been researched along with Familial Periodic Paralysis in 50 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"A Latin-American teenager was begun on a regimen of acetazolamide for a presumptive diagnosis of familial periodic paralysis."7.67Thyrotoxic periodic paralysis in a Latin-American taking acetazolamide. ( Levey, GS; Olson, BR; Shulkin, D, 1989)
"A Latin-American teenager was begun on a regimen of acetazolamide for a presumptive diagnosis of familial periodic paralysis."3.67Thyrotoxic periodic paralysis in a Latin-American taking acetazolamide. ( Levey, GS; Olson, BR; Shulkin, D, 1989)
"Metabolic acidosis was produced in two patients with hypokalemic periodic paralysis by the administration of ammonium chloride over a period of three days."3.65The effect of acidosis in hypokalemic periodic paralysis. ( Greer, M; Jarrell, MA; Maren, TH, 1976)
"Occurrence of a typical MELAS (mitochondrial encephalopathy with lactic acidosis and stroke-like episodes) syndrome in a single member of a large pedigree with episodic weakness associated with a later-onset distal motor neuropathy led to the disclosure of 2 deleterious mitochondrial DNA mutations."1.39Episodic weakness due to mitochondrial DNA MT-ATP6/8 mutations. ( Auré, K; Bedat-Millet, AL; Bouillaud, F; Clarysse, L; Drouin-Garraud, V; Dubourg, O; Fontaine, B; Fournier, E; Gervais-Bernard, H; Jardel, C; Laforêt, P; Lombès, A; Petiot, P; Sternberg, D; Streichenberger, N; Vandier, C; Vial, C, 2013)
"It is likely that this horse's dysphagia, with resultant weight loss and aspiration pneumonia, were clinical manifestations and consequences of HPP."1.29Laryngospasm, dysphagia, and emaciation associated with hyperkalemic periodic paralysis in a horse. ( Breazile, JE; Guglick, MA; MacAllister, CG, 1996)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199039 (78.00)18.7374
1990's5 (10.00)18.2507
2000's3 (6.00)29.6817
2010's2 (4.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Parihar, J1
Chakraborty, P1
Kaul, B1
Statland, JM1
Fontaine, B3
Hanna, MG1
Johnson, NE1
Kissel, JT1
Sansone, VA1
Shieh, PB1
Tawil, RN1
Trivedi, J1
Cannon, SC1
Griggs, RC7
Auré, K1
Dubourg, O1
Jardel, C1
Clarysse, L1
Sternberg, D1
Fournier, E1
Laforêt, P1
Streichenberger, N1
Petiot, P1
Gervais-Bernard, H1
Vial, C1
Bedat-Millet, AL1
Drouin-Garraud, V1
Bouillaud, F1
Vandier, C1
Lombès, A1
Junker, J1
Haverkamp, W1
Schulze-Bahr, E1
Eckardt, L1
Paulus, W1
Kiefer, R1
ALLSOP, JL1
GOULSTON, K1
JOHNSTON, C1
KELLY, D1
RAIL, L1
CARSON, MJ1
PEARSON, CM2
TURPIN, R1
CAILLE, B1
LAFOURCADE, J1
BEBE, M1
NAYRAC, P1
WAROT, P1
FOSSATI, P1
MILBLED, G1
MALAFOSSE, M1
MEIGNIE, S1
SAMAHA, FJ1
Layzer, RB1
Lovelace, RE1
Rowland, LP3
Riggs, JE1
Moxley, RT2
Thompson, AJ1
Hutchinson, M1
Torres, CF1
Bender, AN1
Tengan, CH1
De Oliveira, AS1
Gabbai, AA1
Ptáĉek, LJ1
Tawil, R1
Meola, G1
McManis, P1
Barohn, RJ1
Mendell, JR1
Harris, C1
Spitzer, R1
Santiago, F1
Links, TP2
Smit, AJ1
Molenaar, WM1
Zwarts, MJ2
Oosterhuis, HJ2
Guglick, MA1
MacAllister, CG1
Breazile, JE1
Nakamagoe, K1
Fujita, T1
Ohkoshi, N1
Mizusawa, H1
Shoji, S1
Kurihara, T1
Hoskins, B3
Raphael, JC2
Simon, N2
Goulon, M2
Vroom, FW1
Jarrell, MA4
Maren, TH3
Vroom, FQ2
Johnsen, T2
Schipperheyn, JJ1
Buruma, OJ1
Voogd, PJ1
Greer, M1
Il'ina, NA1
Aver'ianov, IuN1
Anmarkrud, N1
Satoh, J1
Murase, H1
Tsukagoshi, H1
Shulkin, D1
Olson, BR1
Levey, GS1
Kold, A1
Cannon, L1
Bradford, J1
Jones, J1
Sinha, SK1
Sharma, SN1
Prasad, KC1
Mertens, HG1
Lurati, M1
Führ, J1
Lisak, RP2
Lebeau, J2
Tucker, SH2
Viskoper, RJ2
Licht, A1
Fidel, J2
Chaco, J2
Horn, T1
Tzivoni, D1
Zierler, KL1
Kusakabe, T1
Shiotu, H1
Nishikawa, M1
Levitt, LP1
Rose, LI1
Dawson, DM1
Engel, WK2
Resnick, JS2
Norris, FH1
Clark, EC1
Biglieri, EG1
Stam, AC1

Reviews

4 reviews available for acetazolamide and Familial Periodic Paralysis

ArticleYear
Review of the Diagnosis and Treatment of Periodic Paralysis.
    Muscle & nerve, 2018, Volume: 57, Issue:4

    Topics: Acetazolamide; Andersen Syndrome; Anti-Arrhythmia Agents; Behavior Therapy; Carbonic Anhydrase Inhib

2018
[Periodic paralysis: new pathophysiological aspects].
    Bulletin de l'Academie nationale de medecine, 2008, Volume: 192, Issue:8

    Topics: Acetazolamide; Combined Modality Therapy; Dietary Carbohydrates; Diuretics; Electromyography; Exerci

2008
[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia].
    Rinsho shinkeigaku = Clinical neurology, 1997, Volume: 37, Issue:3

    Topics: Abnormalities, Multiple; Acetazolamide; Adult; Arrhythmias, Cardiac; Carbonic Anhydrase Inhibitors;

1997
[Normokalemic periodic paralysis].
    Ryoikibetsu shokogun shirizu, 2001, Issue:35

    Topics: Acetazolamide; Adolescent; Adult; Diagnosis, Differential; Drug Therapy, Combination; Female; Fludro

2001

Trials

4 trials available for acetazolamide and Familial Periodic Paralysis

ArticleYear
Hypokalemic periodic paralysis exacerbated by acetazolamide.
    Neurology, 1981, Volume: 31, Issue:11

    Topics: Acetazolamide; Adolescent; Adult; Blood Glucose; Clinical Trials as Topic; Glucose; Humans; Insulin;

1981
Improvement of muscle strength in familial hypokalaemic periodic paralysis with acetazolamide.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:9

    Topics: Acetazolamide; Adult; Clinical Trials as Topic; Electromyography; Female; Humans; Male; Middle Aged;

1988
Acetazolamide treatment of hypokalemic periodic paralysis. Prevention of attacks and improvement of persistent weakness.
    Annals of internal medicine, 1970, Volume: 73, Issue:1

    Topics: Acetazolamide; Acidosis; Adult; Child; Electrolytes; Female; Humans; Hypokalemia; Male; Middle Aged;

1970
Acetazolamide prophylaxis in hypokalemic periodic paralysis.
    The New England journal of medicine, 1968, Mar-14, Volume: 278, Issue:11

    Topics: Acetazolamide; Adult; Child; Humans; Hyperkalemia; Hypokalemia; Male; Paralyses, Familial Periodic;

1968

Other Studies

42 other studies available for acetazolamide and Familial Periodic Paralysis

ArticleYear
Andersen-Tawil syndrome presenting as premenstrual periodic paralysis.
    Muscle & nerve, 2021, Volume: 63, Issue:1

    Topics: Acetazolamide; Adult; Andersen Syndrome; Female; Humans; Paralyses, Familial Periodic; Paralysis

2021
Episodic weakness due to mitochondrial DNA MT-ATP6/8 mutations.
    Neurology, 2013, Nov-19, Volume: 81, Issue:21

    Topics: Acetazolamide; Adult; Anticonvulsants; Cells, Cultured; DNA, Mitochondrial; Female; Fibroblasts; Hum

2013
Amiodarone and acetazolamide for the treatment of genetically confirmed severe Andersen syndrome.
    Neurology, 2002, Aug-13, Volume: 59, Issue:3

    Topics: Acetazolamide; Adolescent; Amiodarone; Anti-Arrhythmia Agents; Anticonvulsants; Child; Drug Therapy,

2002
FAMILIAL HYPERKALAEMIC PERIODIC PARALYSIS.
    Australasian annals of medicine, 1964, Volume: 13

    Topics: Acetazolamide; Adolescent; Blood Chemical Analysis; Calcium; Electrocardiography; Electromyography;

1964
FAMILIAL HYPERKALEMIC PERIODIC PARALYSIS WITH MYOTONIC FEATURES.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: 17-Ketosteroids; Acetazolamide; Adolescent; Biopsy; Blood Chemical Analysis; Child; Dextroamphetamin

1964
THE PERIODIC PARALYSES: DIFFERENTIAL FEATURES AND PATHOLOGICAL OBSERVATIONS IN PERMANENT MYOPATHIC WEAKNESS.
    Brain : a journal of neurology, 1964, Volume: 87

    Topics: Acetazolamide; Drug Therapy; Epinephrine; Humans; Hydrochlorothiazide; Hydrocortisone; Hyperkalemia;

1964
[A FAMILIAL DISEASE PRESENTING IN CERTAIN SUBJECTS THE APPEARANCE OF EULENBURG'S PARAMYOTONIA AND RESEMBLING IN OTHERS HEREDITARY EPISODIC ADYNAMIA].
    La Presse medicale, 1964, Dec-12, Volume: 72

    Topics: Acetazolamide; Adolescent; Blood; Child; Drug Therapy; Electromyography; Genetics, Medical; Humans;

1964
HYPERKALEMIC PERIODIC PARALYSIS. A GENETIC STUDY, CLINICAL OBSERVATIONS, AND REPORT OF A NEW METHOD OF THERAPY.
    Archives of neurology, 1965, Volume: 12

    Topics: Acetazolamide; Amphetamine; Amphetamines; Chlorothiazide; Electromyography; Genetics, Medical; Human

1965
Hyperkalemic periodic paralysis.
    Archives of neurology, 1967, Volume: 16, Issue:5

    Topics: Acetazolamide; Adolescent; Adult; Aged; Child; Cold Temperature; Electromyography; Female; Glucose T

1967
Dissociation of glucose and potassium arterial-venous differences across the forearm by acetazolamide. A possible relationship to acetazolamide's beneficial effect in hypokalemic periodic paralysis.
    Archives of neurology, 1984, Volume: 41, Issue:1

    Topics: Acetazolamide; Adult; Blood Glucose; Cell Membrane; Dietary Carbohydrates; Female; Forearm; Humans;

1984
Myopathy in hypokalaemic periodic paralysis: reversal with acetazolamide.
    Irish medical journal, 1984, Volume: 77, Issue:6

    Topics: Acetazolamide; Adult; Humans; Hypokalemia; Male; Muscle Hypotonia; Paralyses, Familial Periodic

1984
[Periodic paralysis. Clinical analysis in 20 patients].
    Arquivos de neuro-psiquiatria, 1994, Volume: 52, Issue:4

    Topics: Acetazolamide; Adolescent; Adult; Child; Child, Preschool; Electromyography; Female; Humans; Hyperka

1994
Sodium channel mutations in acetazolamide-responsive myotonia congenita, paramyotonia congenita, and hyperkalemic periodic paralysis.
    Neurology, 1994, Volume: 44, Issue:8

    Topics: Acetazolamide; Autoradiography; Base Sequence; Female; Humans; Hyperkalemia; Male; Molecular Sequenc

1994
Familial hypokalemic periodic paralysis. Clinical, diagnostic and therapeutic aspects.
    Journal of the neurological sciences, 1994, Volume: 122, Issue:1

    Topics: Acetazolamide; Adolescent; Adult; Aged; Child; Creatine Kinase; Electromyography; Female; Genetic Te

1994
Laryngospasm, dysphagia, and emaciation associated with hyperkalemic periodic paralysis in a horse.
    Journal of the American Veterinary Medical Association, 1996, Jul-01, Volume: 209, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Deglutition Disorders; Diagnosis, Differential; Emaciation;

1996
Studies on the mechanism of action of acetazolamide in the prophylaxis of hyperkalemic periodic paralysis.
    Life sciences, 1977, Jan-15, Volume: 20, Issue:2

    Topics: Acetazolamide; Animals; Blood Glucose; Cyclic AMP; Glycogen; Insulin; Liver; Male; Paralyses, Famili

1977
[Paralysis with hypokalemia by transfer, treated by acetazolamide].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, May-23, Volume: 53, Issue:20

    Topics: Acetazolamide; Adolescent; Adult; Female; Glucose Tolerance Test; Humans; Hypokalemia; Infant; Male;

1977
Acetazolamide treatment of hypokalemic periodic paralysis. Probable mechanism of action.
    Archives of neurology, 1975, Volume: 32, Issue:6

    Topics: Acetazolamide; Acidosis; Adult; Blood Glucose; Carbon Dioxide; Erythrocytes; Female; Glucose; Humans

1975
Hyperkalemic periodic paralysis. Effects of potassium, exercise, glucose, and acetazolamide on blood chemistry.
    Archives of neurology, 1975, Volume: 32, Issue:8

    Topics: Acetazolamide; Adult; Bicarbonates; Blood Glucose; Calcium; Child; Chlorides; Female; Humans; Hydrog

1975
Effect upon serum insulin, glucose and potassium concentrations of acetazolamide during attacks of familial periodic hypokalemic paralysis.
    Acta neurologica Scandinavica, 1977, Volume: 56, Issue:6

    Topics: Acetazolamide; Acute Disease; Adolescent; Adult; Blood Glucose; Drug Evaluation; Humans; Hypokalemia

1977
Hypokalaemic periodic paralysis and cardiomyopathy.
    Acta neurologica Scandinavica, 1978, Volume: 58, Issue:6

    Topics: Acetazolamide; Adolescent; Adult; Cardiomyopathies; Echocardiography; Electrocardiography; Female; H

1978
[Periodic familial paralysis with hypokalemia. Hemodynamic and metabolic studies: favourable effect of acetazolamide (author's transl)].
    Revue neurologique, 1978, Volume: 134, Issue:11

    Topics: Acetazolamide; Acid-Base Equilibrium; Adolescent; Blood Pressure; Follow-Up Studies; Heart Rate; Hum

1978
The myotonic disorders and the periodic paralyses.
    Advances in neurology, 1977, Volume: 17

    Topics: Acetazolamide; Benzothiadiazines; Diuretics; Humans; Male; Muscle Contraction; Myotonia; Myotonia Co

1977
The effect of acidosis in hypokalemic periodic paralysis.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Acetazolamide; Acidosis; Adult; Ammonium Chloride; Humans; Hypokalemia; Male; Muscles; Paralyses, Fa

1976
[Treatment of paroxysmal myoplegia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:6

    Topics: Acetazolamide; Adolescent; Adult; Female; Humans; Hyperkalemia; Hypokalemia; Paralyses, Familial Per

1975
[Familial periodic paralysis. Description of a family. Aspects of pathogenesis and treatment of the disease].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Mar-30, Volume: 96, Issue:9-10

    Topics: Acetazolamide; Adolescent; Adult; Female; Humans; Male; Middle Aged; Paralyses, Familial Periodic; P

1976
[Idiopathic hypokalemic periodic paralysis presenting peculiar insulin secretion].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:3

    Topics: Acetazolamide; Adult; Depression, Chemical; Glucose Tolerance Test; Humans; Hypokalemia; Insulin; In

1989
Thyrotoxic periodic paralysis in a Latin-American taking acetazolamide.
    The American journal of the medical sciences, 1989, Volume: 297, Issue:5

    Topics: Acetazolamide; Adolescent; Diagnosis, Differential; Humans; Hyperthyroidism; Male; Paralyses, Famili

1989
[Treatment of familial hypokalemic paralysis with carbon dioxide anhydrase inhibitors].
    Ugeskrift for laeger, 1986, Jul-07, Volume: 148, Issue:28

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans; Hypokalemia; Male; Mi

1986
Hypokalemic periodic paralysis.
    The Journal of emergency medicine, 1986, Volume: 4, Issue:4

    Topics: Acetazolamide; Adult; Diagnosis, Differential; Humans; Hypokalemia; Male; Paralyses, Familial Period

1986
Acetazolamide prophylaxis in hypokalaemic periodic paralysis.
    The Journal of the Association of Physicians of India, 1985, Volume: 33, Issue:6

    Topics: Acetazolamide; Adult; Humans; Hypokalemia; Male; Paralyses, Familial Periodic; Syndrome

1985
Primary periodic paralysis associated with hyperkalemic and hypokalemic attacks and with hemolytic bilirubinemia.
    European neurology, 1968, Volume: 1, Issue:4

    Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Bilirubin; Dexamethasone

1968
Hyperkalemic periodic paralysis and cardiac arrhythmia.
    Neurology, 1972, Volume: 22, Issue:8

    Topics: Acetazolamide; Adolescent; Arrhythmias, Cardiac; Blood Glucose; Electrocardiography; Electromyograph

1972
Acetazolamide treatment in hypokalemic periodic paralysis: a metabolic and electromyographic study.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:2

    Topics: Acetazolamide; Acidosis; Adolescent; Adult; Alkalosis; Ammonium Chloride; Bicarbonates; Electromyogr

1973
On the beneficial action of acetazolamide in hypokalemic periodic paralysis: study of the carbohydrate metabolism.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:2

    Topics: 11-Hydroxycorticosteroids; Acetazolamide; Adolescent; Adult; Ammonium Chloride; Blood Glucose; Carbo

1973
Speculations on hypokalemic periodic paralysis.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:2

    Topics: Acetazolamide; Action Potentials; Cell Membrane Permeability; Electromyography; Humans; Hydrogen-Ion

1973
Metabolic studies on a case of paroxysmal myotonia with periodic paralysis.
    Metabolism: clinical and experimental, 1974, Volume: 23, Issue:3

    Topics: Acetazolamide; Adult; Blood Glucose; Electrolytes; Electromyography; Humans; Hypokalemia; Insulin; M

1974
[Familial periodic hypokalaemic paralysis].
    Ugeskrift for laeger, 1974, Mar-25, Volume: 136, Issue:13

    Topics: Acetazolamide; Adult; Humans; Hypokalemia; Male; Paralyses, Familial Periodic; Potassium

1974
Acetazolamide and potassium flux in red blood cells. Studies in patients with hyperkalemic periodic paralysis.
    Archives of neurology, 1974, Volume: 31, Issue:3

    Topics: Acetazolamide; Administration, Oral; Adult; Bicarbonates; Child, Preschool; Erythrocytes; Female; Hu

1974
Hypokalemic periodic paralysis with arrhythmia.
    The New England journal of medicine, 1972, Feb-03, Volume: 286, Issue:5

    Topics: Acetazolamide; Arrhythmias, Cardiac; Child; Electrocardiography; Heart; Humans; Hyperkalemia; Male;

1972
Hyperkalemic periodic paralysis with cardiac arrhythmia.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Acetazolamide; Adolescent; Child; Female; Humans; Hyperkalemia; Paralyses, Familial Periodic; Phenyt

1970
Studies in thyrotoxic periodic paralysis.
    Journal of the neurological sciences, 1971, Volume: 13, Issue:4

    Topics: 17-Ketosteroids; Acetazolamide; Action Potentials; Adult; Aldosterone; Biopsy; Body Weight; Electrom

1971