acetazolamide has been researched along with Epilepsy, Absence in 24 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined acetazolamide effects in G1D motivated by several longstanding and recent observations: First, the electrographic spike-waves characteristic of absence seizures often resemble those of G1D and, since the 1950s, they have occasionally been treated successfully with acetazolamide, well before G1D was segregated from absence epilepsy as a distinct syndrome." | 4.31 | A concise study of acetazolamide in glucose transporter type 1 deficiency (G1D) epilepsy. ( Avila, A; Málaga, I; Park, JY; Pascual, JM; Primeaux, S, 2023) |
| " Phenobarbital is usually given as well to prevent grand mal seizures." | 3.64 | Treatment of epilepsy. ( BAILEY, AA, 1963) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (87.50) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Málaga, I | 1 |
| Avila, A | 1 |
| Primeaux, S | 1 |
| Park, JY | 1 |
| Pascual, JM | 1 |
| Balaram, N | 1 |
| Jose, J | 1 |
| Gafoor, A | 1 |
| Balachandran, S | 1 |
| Saritha, F | 1 |
| Dileep, KV | 1 |
| Balan, S | 1 |
| GOLLA, FL | 1 |
| HODGE, RS | 1 |
| BAILEY, AA | 1 |
| SCHOLL, ML | 1 |
| POIRE, R | 1 |
| ROYER, P | 1 |
| DEGRAEVE, M | 1 |
| RUSTIN, C | 1 |
| MILLICHAP, JG | 6 |
| JONES, JD | 3 |
| RUDIS, BP | 1 |
| JONGMANS, JW | 1 |
| KIORBOE, E | 1 |
| Thomas, JA | 1 |
| Knotts, GR | 1 |
| Browne, TR | 1 |
| Feldman, RG | 1 |
| Mikati, MA | 1 |
| Burdette, D | 1 |
| Otis, J | 1 |
| Fois, A | 1 |
| Malandrini, F | 1 |
| Mostardini, R | 1 |
| Hagberg, B | 1 |
| Hansson, O | 1 |
| Hooshmand, H | 1 |
| Suter, CG | 1 |
| Jannasch, R | 1 |
| Auckland, NL | 1 |
| Etheridge, JE | 1 |
| Tchicaloff, M | 1 |
| Gamstorp, I | 1 |
| Aymat, F | 1 |
2 reviews available for acetazolamide and Epilepsy, Absence
| Article | Year |
|---|---|
[Antiepileptics. 39].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Aminoglutethimide; Anticonvulsants; Barbiturates; Carbam | 1969 |
Treatment and prognosis of petit mal epilepsy.
Topics: Acetazolamide; Anticonvulsants; Child; Child, Preschool; Drug Synergism; Epilepsy, Absence; Ethosuxi | 1967 |
22 other studies available for acetazolamide and Epilepsy, Absence
| Article | Year |
|---|---|
A concise study of acetazolamide in glucose transporter type 1 deficiency (G1D) epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy, Absence; Glucose Transporter Type 1; Humans; Seizures | 2023 |
Acetazolamide responsive early-onset absence epilepsy and ataxia in a toddler with a KCNA2 genetic variant; a case report.
Topics: Acetazolamide; Ataxia; Child, Preschool; Epilepsy, Absence; Humans; Kv1.2 Potassium Channel | 2023 |
Control of petit mal by acetazolamide.
Topics: Acetazolamide; Epilepsy; Epilepsy, Absence | 1957 |
Treatment of epilepsy.
Topics: Acetazolamide; Anticonvulsants; Automatism; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clon | 1963 |
CURRENT CONCEPTS IN THERAPY: TREATMENT OF SEIZURE DISORDERS (EPILEPSY). (CONCLUDED FROM DECEMBER 12).
Topics: Acetazolamide; Anticonvulsants; Child; Chlordiazepoxide; Dextroamphetamine; Epilepsy; Epilepsy, Abse | 1963 |
[EXPERIMENTAL DETERMINATION OF ANTICONVULSANT PROPERTIES OF DICHLORPHENAMIDE BY ELECTROENCEPHALOGRAPHIC STUDY UNDER INTERMITTENT PHOTIC STIMULATION].
Topics: Acetazolamide; Adolescent; Alcoholism; Anticonvulsants; Anxiety; Bemegride; Dichlorphenamide; Electr | 1963 |
MECHANISM OF ANTICONVULSANT ACTION OF KETOGENIC DIET. STUDIES IN ANIMALS WITH EXPERIMENTAL SEIZURES AND IN CHILDREN WITH PETIT MAL EPILEPSY.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Adolescent; Anticonvulsants; Barbiturates; Biomedica | 1964 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepox | 1964 |
ACID-BASE, ELECTROLYTE, AND AMINO-ACID METABOLISM IN CHILDREN WITH PETIT MAL. ETIOLOGIC SIGNIFICANCE AND MODIFICATION BY ANTICONVULSANT DRUGS AND THE KETOGENIC DIET.
Topics: Acetazolamide; Acid-Base Equilibrium; Adrenocorticotropic Hormone; Amino Acids; Anticonvulsants; Bar | 1964 |
[DRUG THERAPY OF EPILEPSY. INTRODUCTION].
Topics: Acetazolamide; Barbiturates; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epi | 1965 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, T | 1976 |
A nineteen-year-old man with altered mental status.
Topics: Acetazolamide; Adult; Carbamazepine; Diagnosis, Differential; Drug Interactions; Electroencephalogra | 1992 |
Acetazolamide in treatment of epilepsy.
Topics: Acetazolamide; Adult; Child; Epilepsy; Epilepsy, Absence; Humans | 1987 |
Clinical experiences of petit mal.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Electroencephalography; | 1987 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; E | 1972 |
[Anticonvulsants. 7. Treatment of myclonic-astatic epilepsy in small children].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Child, Preschool; Diazepam; Epilepsy, Absence; Epilepsy, | 1971 |
Classification and treatment of seizure disorders in children.
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, | 1970 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mepho | 1970 |
Drugs for petit mal.
Topics: Acetazolamide; Amphetamine; Anticonvulsants; Barbiturates; Child; Child, Preschool; Chlordiazepoxide | 1965 |
The abnormal aminoaciduria in petit mal epilepsy. Further observations in 40 patients and 38 healthy controls.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Blood; Child; Child, Preschool; Epilepsy, Absence; Femal | 1966 |
[New methods of seizure treatment in epilepsy].
Topics: Acetazolamide; Anticonvulsants; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tempo | 1965 |
A clinical trial of tegretol in children with severe epilepsy.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, To | 1966 |