Page last updated: 2024-10-22

acetazolamide and Encephalopathy, Traumatic

acetazolamide has been researched along with Encephalopathy, Traumatic in 3 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"Astrocyte cellular edema is one of the major factors that leads to high morbidity post-mTBI."5.43Acetazolamide Mitigates Astrocyte Cellular Edema Following Mild Traumatic Brain Injury. ( Ali, SF; Balachandran, K; Smith, SG; Sturdivant, NM; Wolchok, JC, 2016)
"Traumatic brain injury is one of the most common pediatric injuries; totaling more than 500,000 emergency department visits per year."1.51Isolated Increased Intracranial Pressure and Unilateral Papilledema in an Infant With Traumatic Brain Injury and Nondepressed Basilar Skull Fracture. ( Dunnick, J; Gesteland, P, 2019)
"Astrocyte cellular edema is one of the major factors that leads to high morbidity post-mTBI."1.43Acetazolamide Mitigates Astrocyte Cellular Edema Following Mild Traumatic Brain Injury. ( Ali, SF; Balachandran, K; Smith, SG; Sturdivant, NM; Wolchok, JC, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dunnick, J1
Gesteland, P1
DeGrauw, X1
Thurman, D1
Xu, L1
Kancherla, V1
DeGrauw, T1
Sturdivant, NM1
Smith, SG1
Ali, SF1
Wolchok, JC1
Balachandran, K1

Other Studies

3 other studies available for acetazolamide and Encephalopathy, Traumatic

ArticleYear
Isolated Increased Intracranial Pressure and Unilateral Papilledema in an Infant With Traumatic Brain Injury and Nondepressed Basilar Skull Fracture.
    Pediatric emergency care, 2019, Volume: 35, Issue:11

    Topics: Acetazolamide; Brain Injuries, Traumatic; Female; Humans; Infant; Intracranial Pressure; Papilledema

2019
Epidemiology of traumatic brain injury-associated epilepsy and early use of anti-epilepsy drugs: An analysis of insurance claims data, 2004-2014.
    Epilepsy research, 2018, Volume: 146

    Topics: Acetazolamide; Adolescent; Adult; Aged; Anticonvulsants; Brain Injuries, Traumatic; Child; Child, Pr

2018
Acetazolamide Mitigates Astrocyte Cellular Edema Following Mild Traumatic Brain Injury.
    Scientific reports, 2016, 09-14, Volume: 6

    Topics: Acetazolamide; Aquaporin 4; Astrocytes; Brain Injuries, Traumatic; Cell Survival; Edema; Gene Expres

2016