Page last updated: 2024-10-22

acetazolamide and Embryopathies

acetazolamide has been researched along with Embryopathies in 4 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"A continuing survey of the genetic variability of different mouse strains to acetazolamide teratogenesis demonstrated the WB/ReJ strain expresses a high frequency of induced subcutaneous edema in day 15 fetuses."7.68Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide. ( Biddle, FG, 1990)
"A continuing survey of the genetic variability of different mouse strains to acetazolamide teratogenesis demonstrated the WB/ReJ strain expresses a high frequency of induced subcutaneous edema in day 15 fetuses."3.68Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide. ( Biddle, FG, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leone, P1
Janson, CG1
McPhee, SJ1
During, MJ1
Rauramo, L1
Kivikoski, A1
Salmi, T1
Biddle, FG1
Aoba, H1

Reviews

1 review available for acetazolamide and Embryopathies

ArticleYear
Global CNS gene transfer for a childhood neurogenetic enzyme deficiency: Canavan disease.
    Current opinion in molecular therapeutics, 1999, Volume: 1, Issue:4

    Topics: Acetates; Acetazolamide; Amidohydrolases; Animals; Aspartic Acid; Brain; Brain Edema; Calcium Compou

1999

Other Studies

3 other studies available for acetazolamide and Embryopathies

ArticleYear
The effect of systematic treatment of toxaemia of pregnancy upon fetal prognosis.
    Annales chirurgiae et gynaecologiae Fenniae, 1975, Volume: 64, Issue:3

    Topics: Acetazolamide; Adult; Chlorothiazide; Dihydralazine; Female; Fetal Death; Fetal Diseases; Furosemide

1975
Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide.
    Teratology, 1990, Volume: 42, Issue:6

    Topics: Acetazolamide; Animals; Crosses, Genetic; Edema; Female; Fetal Diseases; Genetic Predisposition to D

1990
Urinary estriol as an index of placental function.
    The Tohoku journal of experimental medicine, 1966, Jun-25, Volume: 89, Issue:2

    Topics: Acetazolamide; Estriol; Female; Fetal Death; Fetal Diseases; Humans; Placenta; Pre-Eclampsia; Pregna

1966