acetazolamide has been researched along with Dysesthesia in 11 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nine cases of multiple sclerosis with paroxysmal disorders were treated with acetazolamide." | 7.65 | Treatment with acetazolamide of brain-stem and spinal paroxysmal disturbances in multiple sclerosis. ( Alecu, C; Pruskauer-Apostol, B; Voiculescu, V, 1975) |
| "2 g zinc sulphate 3 times daily and a placebo was carried out on 12 patients having grave acetazolamide-induced side-effects manifesting themselves as gustatory disorder, anorexia, and paraesthesia." | 5.05 | Zinc therapy of acetazolamide-induced side-effects. ( Dahl, H; Hilden, J; Nørskov, K; Peitersen, E, 1984) |
| "Nine cases of multiple sclerosis with paroxysmal disorders were treated with acetazolamide." | 3.65 | Treatment with acetazolamide of brain-stem and spinal paroxysmal disturbances in multiple sclerosis. ( Alecu, C; Pruskauer-Apostol, B; Voiculescu, V, 1975) |
| "Familial hemiplegic migraine and episodic ataxia type 2 (EA2) are allelic disorders with distinct types of mutations in the CACNA1A gene." | 2.70 | Efficacy and tolerability of acetazolamide in migraine prophylaxis: a randomised placebo-controlled trial. ( Bousser, MG; Djomby, R; El-Amrani, M; Filipetti, V; Landais, P; Lutz, G; Massiou, H; Taupin, P; Vahedi, K, 2002) |
| "Methazolamide (150 mg/d) was as effective as acetazolamide (500 mg/d) in preventing the symptoms of acute mountain sickness in 20 subjects ascending to 4985 m." | 2.65 | Methazolamide and acetazolamide in acute mountain sickness. ( Bradwell, AR; Fletcher, RF; Wright, AD, 1983) |
| "The risk of paresthesia was increased with all doses." | 2.48 | Reappraisal of acetazolamide for the prevention of acute mountain sickness: a systematic review and meta-analysis. ( Combescure, C; Dumont, L; Haller, G; Kayser, B; Lysakowski, C; Tramèr, MR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nieto Estrada, VH | 1 |
| Molano Franco, D | 1 |
| Medina, RD | 1 |
| Gonzalez Garay, AG | 1 |
| Martí-Carvajal, AJ | 1 |
| Arevalo-Rodriguez, I | 1 |
| Kayser, B | 1 |
| Dumont, L | 1 |
| Lysakowski, C | 1 |
| Combescure, C | 1 |
| Haller, G | 1 |
| Tramèr, MR | 1 |
| JANOWITZ, HD | 1 |
| Wright, AD | 1 |
| Bradwell, AR | 1 |
| Fletcher, RF | 1 |
| Dahl, H | 1 |
| Nørskov, K | 1 |
| Peitersen, E | 1 |
| Hilden, J | 1 |
| Vahedi, K | 1 |
| Taupin, P | 1 |
| Djomby, R | 1 |
| El-Amrani, M | 1 |
| Lutz, G | 1 |
| Filipetti, V | 1 |
| Landais, P | 1 |
| Massiou, H | 1 |
| Bousser, MG | 1 |
| Voiculescu, V | 1 |
| Pruskauer-Apostol, B | 1 |
| Alecu, C | 1 |
| Pesin, SR | 1 |
| Brandt, JD | 1 |
| Friberg, L | 1 |
| Kastrup, J | 1 |
| Rizzi, D | 1 |
| Jensen, JB | 1 |
| Lassen, NA | 1 |
| Kurz, M | 1 |
| Granström, KO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Randomized Double-Blind Control Trial Evaluating the Utility of Continuous Positive Airway Pressure (CPAP) in the Treatment of High Altitude Pulmonary Edema (HAPE)[NCT04186598] | 264 participants (Anticipated) | Interventional | 2020-01-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for acetazolamide and Dysesthesia
| Article | Year |
|---|---|
Interventions for preventing high altitude illness: Part 1. Commonly-used classes of drugs.
Topics: Acetazolamide; Adolescent; Adult; Aged; Altitude Sickness; Brain Edema; Budesonide; Carbonic Anhydra | 2017 |
Reappraisal of acetazolamide for the prevention of acute mountain sickness: a systematic review and meta-analysis.
Topics: Acetazolamide; Altitude Sickness; Carbonic Anhydrase Inhibitors; Humans; Paresthesia; Polyuria; Tast | 2012 |
3 trials available for acetazolamide and Dysesthesia
| Article | Year |
|---|---|
Methazolamide and acetazolamide in acute mountain sickness.
Topics: Acetazolamide; Adult; Altitude Sickness; Clinical Trials as Topic; Female; Humans; Hypoxia; Male; Me | 1983 |
Zinc therapy of acetazolamide-induced side-effects.
Topics: Acetazolamide; Aged; Anorexia; Clinical Trials as Topic; Double-Blind Method; Feeding and Eating Dis | 1984 |
Efficacy and tolerability of acetazolamide in migraine prophylaxis: a randomised placebo-controlled trial.
Topics: Acetazolamide; Adolescent; Adult; Aged; Bicarbonates; Blood Pressure; Calcium Channels, P-Type; Carb | 2002 |
6 other studies available for acetazolamide and Dysesthesia
| Article | Year |
|---|---|
Control of gastric and pancreatic secretion by inhibition of carbonic anhydrase.
Topics: Acetazolamide; Carbonic Anhydrases; Gastric Juice; Humans; Pancreas; Pancreatic Juice; Paresthesia; | 1958 |
Treatment with acetazolamide of brain-stem and spinal paroxysmal disturbances in multiple sclerosis.
Topics: Acetazolamide; Adult; Aged; Brain Stem; Carbamazepine; Diplopia; Female; Humans; Hypesthesia; Male; | 1975 |
Paresthesia and numbness due to drugs: the special case of the blind.
Topics: Acetazolamide; Aged; Blindness; Female; Glaucoma, Angle-Closure; Humans; Paresthesia; Sensory Aids | 1991 |
Cerebral blood flow and end-tidal PCO2 during prolonged acetazolamide treatment in humans.
Topics: Acetazolamide; Adult; Carbon Dioxide; Cerebrovascular Circulation; Female; Hematocrit; Humans; Male; | 1990 |
[Diamox and manifestation of diabetes mellitus].
Topics: Acetazolamide; Anuria; Blood Glucose; Carbonic Anhydrase Inhibitors; Diabetes Mellitus; Humans; Hype | 1968 |
[Side-effects with the Diamox therapy of glaucoma].
Topics: Acetazolamide; Feeding and Eating Disorders; Fingers; Glaucoma; Humans; Paresthesia; Psychophysiolog | 1968 |