Page last updated: 2024-10-22

acetazolamide and Disease Exacerbation

acetazolamide has been researched along with Disease Exacerbation in 15 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"To investigate whether acetazolamide, already found to be helpful in decreasing cystoid macular edema in patients with retinitis pigmentosa, was also effective in the treatment of diabetic macular edema in nonproliferative retinopathy."9.09Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study. ( Forte, R; Gargiulo, P; Giusti, C; Vingolo, EM, 2001)
"Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects."5.51Would acetazolamide inhibit progression of atheromatous vascular calcification? ( Cochran, M, 2019)
"To investigate whether acetazolamide, already found to be helpful in decreasing cystoid macular edema in patients with retinitis pigmentosa, was also effective in the treatment of diabetic macular edema in nonproliferative retinopathy."5.09Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study. ( Forte, R; Gargiulo, P; Giusti, C; Vingolo, EM, 2001)
" The present study was aimed at testing the hypothesis that regional cerebrovascular reactivity (rCVR) to acetazolamide can be a reliable predictor of subsequent ischemic stroke in medically treated patients with internal carotid artery or middle cerebral artery occlusion."5.09Long-term prognosis of medically treated patients with internal carotid or middle cerebral artery occlusion: can acetazolamide test predict it? ( Abe, H; Houkin, K; Iwasaki, Y; Kamiyama, H; Kuroda, S; Mitsumori, K, 2001)
"Meniere's disease is a clinical syndrome of uncertain aetiology but it is a widespread belief that it is related to endolymphatic hydrops."2.43Hypothesis: could Meniere's disease be a channelopathy? ( Gates, P, 2005)
"Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects."1.51Would acetazolamide inhibit progression of atheromatous vascular calcification? ( Cochran, M, 2019)
"Acetazolamide treatment is effective in most cases, and it represents a viable alternative to repeated LP."1.51Pseudotumour cerebri in children: Aetiology, clinical features, and progression. ( Aguilera Albesa, S; Azcona Ganuza, G; Gembero Esarte, E; Iridoy Zulet, M; Mosquera Gorostidi, A; Yoldi Petri, ME, 2019)
"For a diagnosis of idiopathic intracranial hypertension (IIH), she was treated with acetazolamide and methylprednisolone, but vision worsened, so she underwent bilateral optic sheath fenestration (ONSF)."1.35Progressive optic neuropathy in idiopathic intracranial hypertension after optic nerve sheath fenestration. ( Siatkowski, RM; Wilkes, BN, 2009)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's8 (53.33)29.6817
2010's4 (26.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Cochran, M1
Callen, AL1
Dupont, SM1
Pyne, J1
Talbott, J1
Tien, P1
Calabrese, E1
Saloner, D1
Chow, FC1
Narvid, J1
Pramila, PJ1
Mannam, P1
Chacko, AG1
Benjamin, RN1
Albrecht, P1
Blasberg, C1
Ringelstein, M1
Müller, AK1
Finis, D1
Guthoff, R1
Kadas, EM1
Lagreze, W1
Aktas, O1
Hartung, HP1
Paul, F1
Brandt, AU1
Methner, A1
Kim, SJ1
Son, TO1
Kim, KH1
Jeon, P1
Hyun, SH1
Lee, KH1
Yeon, JY1
Kim, JS2
Hong, SC1
Shin, HJ1
Bang, OY1
Mosquera Gorostidi, A1
Iridoy Zulet, M1
Azcona Ganuza, G1
Gembero Esarte, E1
Yoldi Petri, ME1
Aguilera Albesa, S1
Wilkes, BN1
Siatkowski, RM1
Giusti, C1
Forte, R1
Vingolo, EM1
Gargiulo, P1
Lane, M1
McBride, J1
Archer, J1
Gates, P1
Cricchi, F1
Di Lorenzo, C1
Grieco, GS1
Rengo, C1
Cardinale, A1
Racaniello, M1
Santorelli, FM1
Nappi, G1
Pierelli, F1
Casali, C1
Kim, JM1
Ryu, WS1
Hwang, YH1
Golnik, KC1
Devoto, TM1
Kersten, RC1
Kulwin, D1
Yabe, I1
Sasaki, H1
Yamashita, I1
Takei, A1
Tashiro, K1
Kuroda, S1
Houkin, K1
Kamiyama, H1
Mitsumori, K1
Iwasaki, Y1
Abe, H1

Reviews

1 review available for acetazolamide and Disease Exacerbation

ArticleYear
Hypothesis: could Meniere's disease be a channelopathy?
    Internal medicine journal, 2005, Volume: 35, Issue:8

    Topics: Acetazolamide; Adult; Aged; Disease Progression; Endolymphatic Hydrops; Female; Genetic Predispositi

2005

Trials

3 trials available for acetazolamide and Disease Exacerbation

ArticleYear
Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study.
    International ophthalmology, 2001, Volume: 24, Issue:2

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Melli

2001
Clinical trial of acetazolamide in SCA6, with assessment using the Ataxia Rating Scale and body stabilometry.
    Acta neurologica Scandinavica, 2001, Volume: 104, Issue:1

    Topics: Acetazolamide; Adult; Aged; Anticonvulsants; Disease Progression; Female; Humans; Male; Middle Aged;

2001
Long-term prognosis of medically treated patients with internal carotid or middle cerebral artery occlusion: can acetazolamide test predict it?
    Stroke, 2001, Volume: 32, Issue:9

    Topics: Acetazolamide; Aged; Blood Flow Velocity; Brain; Carbonic Anhydrase Inhibitors; Carotid Stenosis; Ce

2001

Other Studies

11 other studies available for acetazolamide and Disease Exacerbation

ArticleYear
Would acetazolamide inhibit progression of atheromatous vascular calcification?
    Medical hypotheses, 2019, Volume: 132

    Topics: Acetazolamide; Acidosis; Aged; Alkaline Phosphatase; Calcium; Disease Progression; Humans; Hydrogen-

2019
The regional pattern of abnormal cerebrovascular reactivity in HIV-infected, virally suppressed women.
    Journal of neurovirology, 2020, Volume: 26, Issue:5

    Topics: Acetazolamide; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Basal Ganglia; Cerebral Arter

2020
Progressive midbrain clefts after head trauma and decompressive surgery: a report of two patients.
    BMJ case reports, 2021, Feb-01, Volume: 14, Issue:2

    Topics: Acetazolamide; Ataxia; Blepharoptosis; Brain Diseases; Brain Injuries, Diffuse; Carbonic Anhydrase I

2021
Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension.
    Journal of neurology, 2017, Volume: 264, Issue:7

    Topics: Acetazolamide; Adult; Algorithms; Atrophy; Carbonic Anhydrase Inhibitors; Case-Control Studies; Dise

2017
Neovascularization precedes occlusion in moyamoya disease: angiographic findings in 172 pediatric patients.
    European neurology, 2014, Volume: 72, Issue:5-6

    Topics: Acetazolamide; Brain; Cardiovascular Agents; Cerebral Angiography; Cerebrovascular Circulation; Chil

2014
Pseudotumour cerebri in children: Aetiology, clinical features, and progression.
    Neurologia, 2019, Volume: 34, Issue:2

    Topics: Acetazolamide; Adolescent; Child; Disease Progression; Female; Humans; Male; Pseudotumor Cerebri; Re

2019
Progressive optic neuropathy in idiopathic intracranial hypertension after optic nerve sheath fenestration.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2009, Volume: 29, Issue:4

    Topics: Acetazolamide; Adolescent; Decompression, Surgical; Disease Progression; Female; Humans; Methylpredn

2009
Steroid responsive late deterioration in Cryptococcus neoformans variety gattii meningitis.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Acetazolamide; Adult; Amphotericin B; Antifungal Agents; Arachnoiditis; Cerebral Infarction; Dexamet

2004
Early-onset progressive ataxia associated with the first CACNA1A mutation identified within the I-II loop.
    Journal of the neurological sciences, 2007, Mar-15, Volume: 254, Issue:1-2

    Topics: Acetazolamide; Age of Onset; Amino Acid Substitution; Calcium Channels; Carbonic Anhydrase Inhibitor

2007
Aggravation of ataxia due to acetazolamide induced hyperammonaemia in episodic ataxia.
    Journal of neurology, neurosurgery, and psychiatry, 2007, Volume: 78, Issue:7

    Topics: Acetazolamide; Acidosis; Ammonia; Ataxia; Carbonic Anhydrase Inhibitors; Disease Progression; Humans

2007
Visual loss in idiopathic intracranial hypertension after resolution of papilledema.
    Ophthalmic plastic and reconstructive surgery, 1999, Volume: 15, Issue:6

    Topics: Acetazolamide; Administration, Oral; Adult; Blindness; Disease Progression; Diuretics; Female; Human

1999