acetazolamide has been researched along with Diabetic Retinopathy in 9 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether acetazolamide, already found to be helpful in decreasing cystoid macular edema in patients with retinitis pigmentosa, was also effective in the treatment of diabetic macular edema in nonproliferative retinopathy." | 9.09 | Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study. ( Forte, R; Gargiulo, P; Giusti, C; Vingolo, EM, 2001) |
| "To investigate whether acetazolamide, already found to be helpful in decreasing cystoid macular edema in patients with retinitis pigmentosa, was also effective in the treatment of diabetic macular edema in nonproliferative retinopathy." | 5.09 | Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study. ( Forte, R; Gargiulo, P; Giusti, C; Vingolo, EM, 2001) |
| "Acetazolamide (ACZ), which is a CAI, is an active substance that has been used off-label for many years in the treatment of macular edema due to diabetes and many other diseases." | 1.91 | Ocular pharmacokinetics and toxicity of nanoparticular acetazolamide: In vivo distribution and safety of PHBV-ACZ nanoparticle. ( Akyol, M; Alçığır, ME; Arslan, A; Bakici, C; Batur, B; Ekim, O; Erdal, E; Salih, B; Uğurlu, N; Yaman, ME, 2023) |
| "CA-I-induced retinal edema was decreased by complement 1 inhibitor, neutralizing antibody to prekallikrein and bradykinin receptor antagonism." | 1.34 | Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation. ( Aiello, LP; Arrigg, PG; Avery, RL; Bursell, SE; Clermont, A; Feener, EP; Fonda, SJ; Fujimoto, JG; Gao, BB; Rook, S; Srinivasan, VJ; Wojtkowski, M, 2007) |
| "Diabetic retinopathy is a highly specific vascular complication of both type 1 and type 2 diabetes, estimated to be the most frequent cause of new cases of blindness in the working population of the Western world." | 1.31 | Is medical treatment for diabetic retinopathy still an unreal dream? ( Giusti, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Erdal, E | 1 |
| Bakici, C | 1 |
| Arslan, A | 1 |
| Batur, B | 1 |
| Yaman, ME | 1 |
| Alçığır, ME | 1 |
| Akyol, M | 1 |
| Ekim, O | 1 |
| Salih, B | 1 |
| Uğurlu, N | 1 |
| Dinç, UA | 1 |
| Yenerel, NM | 1 |
| Görgün, E | 1 |
| Yetik, H | 1 |
| Kokame, GT | 1 |
| Lim, JI | 1 |
| Giusti, C | 2 |
| Forte, R | 1 |
| Vingolo, EM | 1 |
| Gargiulo, P | 1 |
| AURICCHIO, G | 1 |
| DIOTALLEVI, M | 1 |
| Zaidi, FH | 1 |
| Kinnear, PE | 1 |
| Kitano, S | 1 |
| Gao, BB | 1 |
| Clermont, A | 1 |
| Rook, S | 1 |
| Fonda, SJ | 1 |
| Srinivasan, VJ | 1 |
| Wojtkowski, M | 1 |
| Fujimoto, JG | 1 |
| Avery, RL | 1 |
| Arrigg, PG | 1 |
| Bursell, SE | 1 |
| Aiello, LP | 1 |
| Feener, EP | 1 |
| Yonemura, D | 1 |
| Kawasaki, K | 1 |
1 review available for acetazolamide and Diabetic Retinopathy
| Article | Year |
|---|---|
[Medications for diabetic macular edema].
Topics: Acetazolamide; Diabetic Retinopathy; Diagnostic Techniques, Ophthalmological; Humans; Indoles; Injec | 2005 |
1 trial available for acetazolamide and Diabetic Retinopathy
| Article | Year |
|---|---|
Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Melli | 2001 |
7 other studies available for acetazolamide and Diabetic Retinopathy
| Article | Year |
|---|---|
Ocular pharmacokinetics and toxicity of nanoparticular acetazolamide: In vivo distribution and safety of PHBV-ACZ nanoparticle.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Diabetic Retinopathy; Glaucoma; Humans; Intraocular Pr | 2023 |
Diagnostic and therapeutic challenges.
Topics: Acetazolamide; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; B | 2009 |
Is medical treatment for diabetic retinopathy still an unreal dream?
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Diabetic Retinopathy; Hemostatics; Humans; Octreotide; | 2002 |
[A NEW METHOD FOR THE MEASUREMENT OF THE RATE OF FORMATION OF AQUEOUS HUMOR: THE "RECOVERY RATE" ACCORDING TO OKUN].
Topics: Acetazolamide; Aqueous Humor; Cataract; Diabetic Retinopathy; Eye Diseases; Glaucoma; Humans; Intrao | 1963 |
Acetazolamide, alternate carbonic anhydrase inhibitors and hypoglycaemic agents: comparing enzymatic with diuresis induced metabolic acidosis following intraocular surgery in diabetes.
Topics: Acetazolamide; Acidosis; Carbonic Anhydrase Inhibitors; Diabetes Mellitus, Type 1; Diabetic Retinopa | 2004 |
Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation.
Topics: Acetazolamide; Animals; Blotting, Western; Bradykinin Receptor Antagonists; Capillary Permeability; | 2007 |
New approaches to ophthalmic electrodiagnosis by retinal oscillatory potential, drug-induced responses from retinal pigment epithelium and cone potential.
Topics: Acetazolamide; Adolescent; Adult; Animals; Child; Color Vision Defects; Diabetic Retinopathy; Electr | 1979 |