Page last updated: 2024-10-22

acetazolamide and Diabetes Mellitus, Type 2

acetazolamide has been researched along with Diabetes Mellitus, Type 2 in 12 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
"To investigate whether acetazolamide, already found to be helpful in decreasing cystoid macular edema in patients with retinitis pigmentosa, was also effective in the treatment of diabetic macular edema in nonproliferative retinopathy."9.09Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study. ( Forte, R; Gargiulo, P; Giusti, C; Vingolo, EM, 2001)
"Acetazolamide did not produce a natriuresis in the DIURESIS-CHF trial, and in ADVOR, immediate effects on symptoms and body weight were not reported, and the drug had no effect on morbidity or mortality after 90 days."7.01Similarities and distinctions between acetazolamide and sodium-glucose cotransporter 2 inhibitors in patients with acute heart failure: Key insights into ADVOR and EMPULSE. ( Butler, J; Packer, M, 2023)
"To investigate whether acetazolamide, already found to be helpful in decreasing cystoid macular edema in patients with retinitis pigmentosa, was also effective in the treatment of diabetic macular edema in nonproliferative retinopathy."5.09Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study. ( Forte, R; Gargiulo, P; Giusti, C; Vingolo, EM, 2001)
"Acetazolamide did not produce a natriuresis in the DIURESIS-CHF trial, and in ADVOR, immediate effects on symptoms and body weight were not reported, and the drug had no effect on morbidity or mortality after 90 days."3.01Similarities and distinctions between acetazolamide and sodium-glucose cotransporter 2 inhibitors in patients with acute heart failure: Key insights into ADVOR and EMPULSE. ( Butler, J; Packer, M, 2023)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's2 (16.67)18.2507
2000's7 (58.33)29.6817
2010's0 (0.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Artasensi, A1
Angeli, A1
Lammi, C1
Bollati, C1
Gervasoni, S1
Baron, G1
Matucci, R1
Supuran, CT1
Vistoli, G1
Fumagalli, L1
Packer, M1
Butler, J1
Dinç, UA1
Yenerel, NM1
Görgün, E1
Yetik, H1
Kokame, GT1
Lim, JI1
Elinav, E1
Ackerman, Z1
Gottehrer, NP1
Heyman, SN1
Giusti, C1
Forte, R1
Vingolo, EM1
Gargiulo, P1
Horita, Y1
Hayashida, K1
Fukuchi, K1
Takishita, S1
Tadokoro, M1
Taura, K1
Suyama, N1
Miyazaki, M1
Kohno, S1
Kawano, Y1
Chazova, IE1
Mychka, VB1
Gornostaev, VV1
Dvoskina, IM1
Sergienko, VB1
Rames, I1
Kristufek, V1
Rousseau, P1
Fuentevilla-Clifton, A1
Fülesdi, B1
Limburg, M1
Molnár, C1
Káplár, M1
Bereczki, D1
Neuwirth, G1
Csiba, L1
Leys, A1
Vandenberghe, P1
Krott, R1
Heller, R1
Aisenbrey, S1
Bartz-Schmidt, KU1

Reviews

2 reviews available for acetazolamide and Diabetes Mellitus, Type 2

ArticleYear
Similarities and distinctions between acetazolamide and sodium-glucose cotransporter 2 inhibitors in patients with acute heart failure: Key insights into ADVOR and EMPULSE.
    European journal of heart failure, 2023, Volume: 25, Issue:9

    Topics: Acetazolamide; Body Weight; Diabetes Mellitus, Type 2; Diuretics; Glucose; Heart Failure; Humans; So

2023
[Cerebrovascular reactivity in non-insulin dependent diabetes mellitus (preliminary results)].
    Orvosi hetilap, 1998, Jul-26, Volume: 139, Issue:30

    Topics: Acetazolamide; Aged; Blood Flow Velocity; Cerebrovascular Circulation; Diabetes Mellitus, Type 2; Fe

1998

Trials

4 trials available for acetazolamide and Diabetes Mellitus, Type 2

ArticleYear
Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study.
    International ophthalmology, 2001, Volume: 24, Issue:2

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Melli

2001
Acetazolamide assisted Tc-99m MAG3 renography to assess renal blood flow reserve.
    Annals of nuclear medicine, 2003, Volume: 17, Issue:2

    Topics: Acetazolamide; Blood Flow Velocity; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans

2003
[Effect of different saluretics on carbohydrate metabolism and blood pressure behavior in diabetics].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1984, Volume: 44, Issue:2

    Topics: Acetazolamide; Aged; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Chronic Disease; Clinic

1984
[Cerebrovascular reactivity in non-insulin dependent diabetes mellitus (preliminary results)].
    Orvosi hetilap, 1998, Jul-26, Volume: 139, Issue:30

    Topics: Acetazolamide; Aged; Blood Flow Velocity; Cerebrovascular Circulation; Diabetes Mellitus, Type 2; Fe

1998

Other Studies

7 other studies available for acetazolamide and Diabetes Mellitus, Type 2

ArticleYear
Discovery of a Potent and Highly Selective Dipeptidyl Peptidase IV and Carbonic Anhydrase Inhibitor as "Antidiabesity" Agents Based on Repurposing and Morphing of WB-4101.
    Journal of medicinal chemistry, 2022, 10-27, Volume: 65, Issue:20

    Topics: Adrenergic Agents; Caco-2 Cells; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Diabetes Mellit

2022
Diagnostic and therapeutic challenges.
    Retina (Philadelphia, Pa.), 2009, Volume: 29, Issue:2

    Topics: Acetazolamide; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; B

2009
Recurrent life-threatening acidosis induced by acetazolamide in a patient with diabetic type IV renal tubular acidosis.
    Annals of emergency medicine, 2002, Volume: 40, Issue:2

    Topics: Acetazolamide; Acidosis; Aged; Aged, 80 and over; Bicarbonates; Carbonic Anhydrase Inhibitors; Diabe

2002
[Cerebral perfusion in patients with metabolic syndrome].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2005, Issue:Suppl 13

    Topics: Acetazolamide; Adult; Brain; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Cerebrovasc

2005
Acetazolamide and salicylate interaction in the elderly: a case report.
    Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:8

    Topics: Acetazolamide; Acidosis, Lactic; Aged; Anorexia; Confusion; Coronary Disease; Diabetes Mellitus, Typ

1993
Serous macular detachments in a patient with IgM paraproteinemia: an optical coherence tomography study.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:6

    Topics: Acetazolamide; Aged; Diabetes Mellitus, Type 2; Diagnostic Techniques, Ophthalmological; Fluorescein

2001
Adjunctive hyperbaric oxygenation in macular edema of vascular origin.
    Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2000,Winter, Volume: 27, Issue:4

    Topics: Acetazolamide; Aged; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diuretics; Emergencies; F

2000