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acetazolamide and Demyelinating Diseases

acetazolamide has been researched along with Demyelinating Diseases in 2 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Research Excerpts

ExcerptRelevanceReference
"We report successful treatment of paroxysmal dystonia (tonic seizures) in three patients with central demyelinating disease (CDD) using acetazolamide alone or in combination with carbamazepine."7.68Acetazolamide treatment of paroxysmal dystonia in central demyelinating disease. ( Adams, RJ; Hess, DC; Huffnagle, VH; Sethi, KD, 1992)
"We report successful treatment of paroxysmal dystonia (tonic seizures) in three patients with central demyelinating disease (CDD) using acetazolamide alone or in combination with carbamazepine."3.68Acetazolamide treatment of paroxysmal dystonia in central demyelinating disease. ( Adams, RJ; Hess, DC; Huffnagle, VH; Sethi, KD, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oishi, M1
Mochizuki, Y1
Hara, M1
Takasu, T1
Sethi, KD1
Hess, DC1
Huffnagle, VH1
Adams, RJ1

Other Studies

2 other studies available for acetazolamide and Demyelinating Diseases

ArticleYear
Central motor conduction time in patients with periventricular lucencies.
    Journal of the neurological sciences, 1996, Volume: 142, Issue:1-2

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cerebral Ventricles; Cerebral Ventriculography; Cerebr

1996
Acetazolamide treatment of paroxysmal dystonia in central demyelinating disease.
    Neurology, 1992, Volume: 42, Issue:4

    Topics: Acetazolamide; Adult; Central Nervous System Diseases; Demyelinating Diseases; Dystonia; Female; Hum

1992