acetazolamide has been researched along with Delayed Effects, Prenatal Exposure in 6 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Development of metabolic acidosis, hypocalcemia and hypomagnesemia in a preterm infant whose mother was treated with acetazolamide throughout pregnancy is described." | 7.68 | Possible association between acetazolamide administration during pregnancy and metabolic disorders in the newborn. ( Litwin, A; Merlob, P; Mor, N, 1990) |
| " His mother had glaucoma and had been treated during pregnancy with oral acetazolamide, a carbonic anhydrase inhibitor." | 3.71 | Transient renal tubular acidosis in a neonate following transplacental acetazolamide. ( Azuma, E; Higashigawa, M; Komada, Y; Mukouhara, R; Ozawa, H; Shindo, K, 2001) |
| "Development of metabolic acidosis, hypocalcemia and hypomagnesemia in a preterm infant whose mother was treated with acetazolamide throughout pregnancy is described." | 3.68 | Possible association between acetazolamide administration during pregnancy and metabolic disorders in the newborn. ( Litwin, A; Merlob, P; Mor, N, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weaver, TE | 2 |
| Scott, WJ | 2 |
| Kojima, N | 1 |
| Naya, M | 1 |
| Makita, T | 1 |
| Sherman, GF | 1 |
| Holmes, LB | 1 |
| Ozawa, H | 1 |
| Azuma, E | 1 |
| Shindo, K | 1 |
| Higashigawa, M | 1 |
| Mukouhara, R | 1 |
| Komada, Y | 1 |
| Merlob, P | 1 |
| Litwin, A | 1 |
| Mor, N | 1 |
6 other studies available for acetazolamide and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Acetazolamide teratogenesis: association of maternal respiratory acidosis and ectrodactyly in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Acidosis, Respiratory; Animals; Carbon Dioxide; Dose-Res | 1984 |
Acetazolamide teratogenesis: interaction of maternal metabolic and respiratory acidosis in the induction of ectrodactyly in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Acidosis; Acidosis, Respiratory; Animals; Carbon Dioxide | 1984 |
Effects of maternal acetazolamide treatment on body weights and incisor development of the fetal rat.
Topics: Acetazolamide; Administration, Oral; Animals; Body Weight; Carbonic Anhydrase Inhibitors; Embryonic | 1999 |
Cerebrocortical microdysgenesis is enhanced in c57BL/6J mice exposed in utero to acetazolamide.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Cerebral Cortex; Female; Mice; Mice, Inbred C | 1999 |
Transient renal tubular acidosis in a neonate following transplacental acetazolamide.
Topics: Acetazolamide; Acidosis, Renal Tubular; Carbonic Anhydrase Inhibitors; Diuretics; Female; Glaucoma; | 2001 |
Possible association between acetazolamide administration during pregnancy and metabolic disorders in the newborn.
Topics: Acetazolamide; Acidosis; Adult; Female; Humans; Hypocalcemia; Infant, Newborn; Magnesium; Metabolic | 1990 |