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acetazolamide and Convulsions, Grand Mal

acetazolamide has been researched along with Convulsions, Grand Mal in 14 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."7.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
"Phenytoin produced a lower serum level than the same dose of its sodium salt."5.25Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. ( Gamstorp, I; Lilienberg, G; Norell, E, 1975)
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."3.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
" Phenobarbital is usually given as well to prevent grand mal seizures."3.64Treatment of epilepsy. ( BAILEY, AA, 1963)
"Phenytoin produced a lower serum level than the same dose of its sodium salt."1.25Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. ( Gamstorp, I; Lilienberg, G; Norell, E, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199014 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BAILEY, AA1
POIRE, R1
ROYER, P1
DEGRAEVE, M1
RUSTIN, C1
MACGREGOR, M1
JONGMANS, JW1
KIORBOE, E1
Forsythe, WI1
Owens, JR1
Toothill, C1
Shaywitz, BA1
Cohen, DJ1
Bowers, MB1
Norell, E1
Lilienberg, G1
Gamstorp, I2
Thomas, JA1
Knotts, GR1
Millichap, JG1
Hagberg, B1
Hansson, O1
Hooshmand, H1
Suter, CG1
Jannasch, R1

Reviews

1 review available for acetazolamide and Convulsions, Grand Mal

ArticleYear
[Antiepileptics. 39].
    Pharmazeutische Praxis, 1969, Volume: 10

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Aminoglutethimide; Anticonvulsants; Barbiturates; Carbam

1969

Other Studies

13 other studies available for acetazolamide and Convulsions, Grand Mal

ArticleYear
Treatment of epilepsy.
    Canadian Medical Association journal, 1963, Jun-29, Volume: 88

    Topics: Acetazolamide; Anticonvulsants; Automatism; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clon

1963
[EXPERIMENTAL DETERMINATION OF ANTICONVULSANT PROPERTIES OF DICHLORPHENAMIDE BY ELECTROENCEPHALOGRAPHIC STUDY UNDER INTERMITTENT PHOTIC STIMULATION].
    Annales medicales de Nancy, 1963, Volume: 2

    Topics: Acetazolamide; Adolescent; Alcoholism; Anticonvulsants; Anxiety; Bemegride; Dichlorphenamide; Electr

1963
EPILEPSY IN CHILDHOOD: CLASSIFICATION AND TREATMENT.
    Postgraduate medical journal, 1964, Volume: 40

    Topics: Acetazolamide; Adrenal Cortex Hormones; Angiomatosis; Barbiturates; Child; Classification; Electroen

1964
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
    Epilepsia, 1964, Volume: 5

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepox

1964
[DRUG THERAPY OF EPILEPSY. INTRODUCTION].
    Nordisk medicin, 1965, Mar-11, Volume: 73

    Topics: Acetazolamide; Barbiturates; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epi

1965
Effectiveness of acetazolamide in the treatment of carbamazepine-resistant epilepsy in children.
    Developmental medicine and child neurology, 1981, Volume: 23, Issue:6

    Topics: Acetazolamide; Adolescent; Carbamazepine; Child; Child, Preschool; Drug Resistance; Drug Therapy, Co

1981
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
    Neurology, 1975, Volume: 25, Issue:1

    Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy

1975
Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy.
    European neurology, 1975, Volume: 13, Issue:3

    Topics: Acetazolamide; Adolescent; Carbamazepine; Child; Child, Preschool; Contraceptives, Oral; Drug Intera

1975
Epilepsy and other seizure disorders in children: drug management.
    The Journal of school health, 1976, Volume: 46, Issue:8

    Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, T

1976
Drug treatment of convulsive disorders.
    The New England journal of medicine, 1972, Mar-02, Volume: 286, Issue:9

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; E

1972
[Anticonvulsants. 7. Treatment of myclonic-astatic epilepsy in small children].
    Lakartidningen, 1971, Oct-18, Volume: 68

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Child, Preschool; Diazepam; Epilepsy, Absence; Epilepsy,

1971
Classification and treatment of seizure disorders in children.
    Virginia medical monthly, 1970, Volume: 97, Issue:2

    Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child,

1970
A clinical trial of tegretol in children with severe epilepsy.
    Developmental medicine and child neurology, 1966, Volume: 8, Issue:3

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, To

1966