acetazolamide has been researched along with Colorectal Neoplasms in 5 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we aimed to investigate the effect of acetazolamide, which is a classical carbonic anhydrase inhibitor, on the cell viability, migration, and colony forming capacity of human LS174T colorectal cancer cells." | 3.88 | Inhibition of cell proliferation, migration and colony formation of LS174T Cells by carbonic anhydrase inhibitor. ( Eyol, E; Karakuş, F; Ünüvar, S; Yılmaz, K, 2018) |
| "Tumor hypoxia is a common feature in colorectal cancer (CRC), and is associated with resistance to radiotherapy and chemotherapy." | 1.62 | A novel ( Chen, CT; Guan, SS; Liao, TZ; Lin, KL; Liu, SH; Peng, CL; Shih, YH; Wang, YC; Weng, MF; Wu, CT; Yeh, CH, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grandane, A | 1 |
| Tanc, M | 1 |
| Di Cesare Mannelli, L | 1 |
| Carta, F | 1 |
| Ghelardini, C | 1 |
| Žalubovskis, R | 1 |
| Supuran, CT | 1 |
| Guan, SS | 1 |
| Wu, CT | 1 |
| Liao, TZ | 1 |
| Lin, KL | 1 |
| Peng, CL | 1 |
| Shih, YH | 1 |
| Weng, MF | 1 |
| Chen, CT | 1 |
| Yeh, CH | 1 |
| Wang, YC | 1 |
| Liu, SH | 1 |
| Karakuş, F | 1 |
| Eyol, E | 1 |
| Yılmaz, K | 1 |
| Ünüvar, S | 1 |
| Wichert, M | 1 |
| Krall, N | 1 |
| Faes, S | 1 |
| Planche, A | 1 |
| Uldry, E | 1 |
| Santoro, T | 1 |
| Pythoud, C | 1 |
| Stehle, JC | 1 |
| Horlbeck, J | 1 |
| Letovanec, I | 1 |
| Riggi, N | 1 |
| Datta, D | 1 |
| Demartines, N | 1 |
| Dormond, O | 1 |
1 review available for acetazolamide and Colorectal Neoplasms
| Article | Year |
|---|---|
Targeting carbonic anhydrase IX with small organic ligands.
Topics: Acetazolamide; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Ca | 2015 |
4 other studies available for acetazolamide and Colorectal Neoplasms
| Article | Year |
|---|---|
6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Benzamides; Carbonic Anhydrase Inhibitors; Carbonic Anhyd | 2015 |
A novel
Topics: Acetazolamide; Animals; Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Ce | 2021 |
Inhibition of cell proliferation, migration and colony formation of LS174T Cells by carbonic anhydrase inhibitor.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Cell Line, Tumor; Cell Movement; Cell Proliferation; C | 2018 |
Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors.
Topics: Acetazolamide; Animals; Antibiotics, Antineoplastic; Carbonic Anhydrase Inhibitors; Carbonic Anhydra | 2016 |