Page last updated: 2024-10-22

acetazolamide and Chronic Disease

acetazolamide has been researched along with Chronic Disease in 96 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to determine the diuretic effect of acetazolamide in patients with exacerbations of chronic heart failure, in addition to their stable diuretic therapy."9.24Acetazolamide as Add-on Diuretic Therapy in Exacerbations of Chronic Heart Failure: a Pilot Study. ( Budaj, A; Imiela, T, 2017)
"To study the effect of acetazolamide on cystoid macular edema in patients with uveitis."9.08A randomized, masked, cross-over trial of acetazolamide for cystoid macular edema in patients with uveitis. ( Chew, EY; Csaky, KG; Nussenblatt, RB; Perry, CH; Podgor, MJ; Whitcup, SM, 1996)
", West Point, PA), a carbonic anhydrase inhibitor, with that of oral acetazolamide (Diamox; Lederle Laboratories, Pearl River, NY) for the management of chronic cystoid macular edema in patients with retinitis pigmentosa."9.08Efficacy of dorzolamide hydrochloride in the management of chronic cystoid macular edema in patients with retinitis pigmentosa. ( Adelman, AE; Fiscella, RG; Fishman, GA; Grover, S, 1997)
"Thirty patients with cystoid macular oedema secondary to chronic iridocyclitis were enrolled in a two period, prospective, randomised, double masked, crossover study that compared sustained release acetazolamide (500 mg twice a day) with a placebo to measure the effects on the reduction of cystoid macular oedema and improvement of visual acuity."9.07Reduction of macular oedema by acetazolamide in patients with chronic iridocyclitis: a randomised prospective crossover study. ( Cross, A; Farber, MD; Jennings, TJ; Lam, S; Rusin, MM; Tessler, HH, 1994)
"We tested the effect of acetazolamide on blood mechanical properties and pulmonary vascular resistance (PVR) during chronic hypoxia."7.78Acetazolamide and chronic hypoxia: effects on haemorheology and pulmonary haemodynamics. ( Brunet, J; Connes, P; Cymbalista, F; Favret, F; Levy, BI; Maignan, M; Marchant, D; Pichon, A; Quidu, P; Richalet, JP; Safeukui, I; Vilar, J, 2012)
"Cerebral blood flow (CBF) and response to acetazolamide were measured during the acute, subacute, and chronic stages after aneurysmal subarachnoid hemorrhage and correlated with symptomatic vasospasm and clinical outcome in 45 patients who underwent early clipping of ruptured cerebral aneurysms, of whom 18 had symptomatic vasospasm and 27 did not."7.70Cerebral blood flow and the response to acetazolamide during the acute, subacute, and chronic stages of aneurysmal subarachnoid hemorrhage. ( Nakayama, Y; Tanaka, A; Tomonaga, M; Yoshinaga, S, 1998)
"The aim of this study was to compare the effect of vasodilative stimuli for the measurement of cerebrovascular reactivity obtained by acetazolamide and hypercapnia in patients with chronic occlusive major cerebral artery disease."7.69Dissociation of vasoreactivity to acetazolamide and hypercapnia. Comparative study in patients with chronic occlusive major cerebral artery disease. ( Houkin, K; Ishikawa, T; Kazumata, K; Kuroda, S; Mitsumori, K; Tanaka, N, 1996)
"To evaluate the efficacy of 133Xe SPECT and Diamox test, for selecting patients with hemodynamic compromise, tests using 133Xe inhalation method and single photon emission computed tomography (SPECT) with acetazolamide (Diamox) were performed in twenty-three patients with chronic cerebral ischemia, before and after extracranial-intracranial bypass surgery or carotid-endarterectomy."7.68[Diagnosis of hemodynamic compromise in patients with chronic cerebral ischemia; the detection of impaired vasodilatory capacity with 133Xe SPECT and acetazolamide (Diamox) test]. ( Abe, H; Kamiyama, H; Kuroda, S; Mitsumori, K; Motomiya, M; Nakagawa, T; Sakuragi, M; Takigawa, S; Tsuru, M, 1990)
"In a prospective study, 41 patients with documented chronic macular edema of various causes were entered into a therapeutic trial of acetazolamide sodium, a carbonic anhydrase inhibitor."7.67Treatment of chronic macular edema with acetazolamide. ( Bird, AC; Cox, SN; Hay, E, 1988)
"CVR is impaired in alert patients with cerebral infarction, although the mean CBF is not reduced, and good collateral flow via the anterior communicating artery in patients with carotid occlusion may be a sign of well-preserved haemodynamic status."6.70Cerebrovascular reactivity to acetazolamide in alert patients with cerebral infarction: usefulness of first-pass radionuclide angiography using 99m Tc-HMPAO in monitoring cerebral haemodynamics. ( Chang, CC; Kanno, H; Kuwana, N; Yamamoto, I, 2001)
"Acetazolamide treatment did not significantly affect the expression of vascular endothelial growth factor in the tissues studied."5.36Aquaporin-1 expression and angiogenesis in rabbit chronic myocardial ischemia is decreased by acetazolamide. ( Chen, Y; Liang, Y; Liu, W; Lv, X; Ran, X; Sun, J; Wang, B; Wang, H; Zeng, Z; Zhang, K; Zheng, R; Zhou, Q, 2010)
"The aim of this study was to determine the diuretic effect of acetazolamide in patients with exacerbations of chronic heart failure, in addition to their stable diuretic therapy."5.24Acetazolamide as Add-on Diuretic Therapy in Exacerbations of Chronic Heart Failure: a Pilot Study. ( Budaj, A; Imiela, T, 2017)
"Although the effects of acetazolamide (ACZ) on ventilation during acute mountain sickness are well known, there are no studies assessing its effect on ventilatory response in chronic hypoxia."5.13Effect of acetazolamide on ventilatory response in subjects with chronic mountain sickness. ( Bouchet, P; Huicho, L; León-Velarde, F; Richalet, JP; Rivera-Ch, M, 2008)
"To study the effect of acetazolamide on cystoid macular edema in patients with uveitis."5.08A randomized, masked, cross-over trial of acetazolamide for cystoid macular edema in patients with uveitis. ( Chew, EY; Csaky, KG; Nussenblatt, RB; Perry, CH; Podgor, MJ; Whitcup, SM, 1996)
", West Point, PA), a carbonic anhydrase inhibitor, with that of oral acetazolamide (Diamox; Lederle Laboratories, Pearl River, NY) for the management of chronic cystoid macular edema in patients with retinitis pigmentosa."5.08Efficacy of dorzolamide hydrochloride in the management of chronic cystoid macular edema in patients with retinitis pigmentosa. ( Adelman, AE; Fiscella, RG; Fishman, GA; Grover, S, 1997)
"Thirty patients with cystoid macular oedema secondary to chronic iridocyclitis were enrolled in a two period, prospective, randomised, double masked, crossover study that compared sustained release acetazolamide (500 mg twice a day) with a placebo to measure the effects on the reduction of cystoid macular oedema and improvement of visual acuity."5.07Reduction of macular oedema by acetazolamide in patients with chronic iridocyclitis: a randomised prospective crossover study. ( Cross, A; Farber, MD; Jennings, TJ; Lam, S; Rusin, MM; Tessler, HH, 1994)
"We tested the effect of acetazolamide on blood mechanical properties and pulmonary vascular resistance (PVR) during chronic hypoxia."3.78Acetazolamide and chronic hypoxia: effects on haemorheology and pulmonary haemodynamics. ( Brunet, J; Connes, P; Cymbalista, F; Favret, F; Levy, BI; Maignan, M; Marchant, D; Pichon, A; Quidu, P; Richalet, JP; Safeukui, I; Vilar, J, 2012)
"Three normal volunteers and 12 patients with an obstruction of major cerebral arteries underwent PET measurements of the CBF after an injection of H2(15)O: (1) in the resting condition, (2) during hyperventilation (HV scan), (3) 1 to 3 minutes after hyperventilation (post-HV scan), (4) during the inhalation of 5% CO2, and (5) after an injection of acetazolamide."3.70Posthyperventilatory steal response in chronic cerebral hemodynamic stress: a positron emission tomography study. ( Hirakawa, K; Ishii, K; Matsushima, Y; Nariai, T; Senda, M; Toyama, H; Wakabayashi, S; Yokota, T, 1998)
"Cerebral blood flow (CBF) and response to acetazolamide were measured during the acute, subacute, and chronic stages after aneurysmal subarachnoid hemorrhage and correlated with symptomatic vasospasm and clinical outcome in 45 patients who underwent early clipping of ruptured cerebral aneurysms, of whom 18 had symptomatic vasospasm and 27 did not."3.70Cerebral blood flow and the response to acetazolamide during the acute, subacute, and chronic stages of aneurysmal subarachnoid hemorrhage. ( Nakayama, Y; Tanaka, A; Tomonaga, M; Yoshinaga, S, 1998)
"The aim of this study was to compare the effect of vasodilative stimuli for the measurement of cerebrovascular reactivity obtained by acetazolamide and hypercapnia in patients with chronic occlusive major cerebral artery disease."3.69Dissociation of vasoreactivity to acetazolamide and hypercapnia. Comparative study in patients with chronic occlusive major cerebral artery disease. ( Houkin, K; Ishikawa, T; Kazumata, K; Kuroda, S; Mitsumori, K; Tanaka, N, 1996)
"To assess the responsiveness of the cerebral vessels to chronic hypercapnia, we measured middle cerebral artery flow velocity by transcranial Doppler ultrasound in 20 normal subjects and in 14 COLD patients before and after stimulation by progressive hypercapnia (rebreathing test) or by intravenous administration of an acetazolamide bolus."3.68Cerebral vascular responsiveness in chronic hypercapnia. ( Cavestri, R; Ciofetti, M; Clivati, A; Longhini, E, 1992)
"To evaluate the efficacy of 133Xe SPECT and Diamox test, for selecting patients with hemodynamic compromise, tests using 133Xe inhalation method and single photon emission computed tomography (SPECT) with acetazolamide (Diamox) were performed in twenty-three patients with chronic cerebral ischemia, before and after extracranial-intracranial bypass surgery or carotid-endarterectomy."3.68[Diagnosis of hemodynamic compromise in patients with chronic cerebral ischemia; the detection of impaired vasodilatory capacity with 133Xe SPECT and acetazolamide (Diamox) test]. ( Abe, H; Kamiyama, H; Kuroda, S; Mitsumori, K; Motomiya, M; Nakagawa, T; Sakuragi, M; Takigawa, S; Tsuru, M, 1990)
"In a prospective study, 41 patients with documented chronic macular edema of various causes were entered into a therapeutic trial of acetazolamide sodium, a carbonic anhydrase inhibitor."3.67Treatment of chronic macular edema with acetazolamide. ( Bird, AC; Cox, SN; Hay, E, 1988)
"Multiple serum chemical values were examined in 92 patients with chronic glaucoma who were treated with the carbonic anhydrase inhibitors (CAIs) acetazolamide or methazolamide, seeking relationships between serum composition and symptomatic side effects."3.65Carbonic anhydrase inhibitor side effects. Serum chemical analysis. ( Epstein, DL; Grant, WM, 1977)
"Fifteen patients with carotid artery stenosis ≥ 90% on the ipsilateral side and <50% on the contralateral side were enrolled into the study."2.78Near-infrared transillumination back scattering sounding--new method to assess brain microcirculation in patients with chronic carotid artery stenosis. ( Bandurski, T; Frydrychowski, AF; Halena, G; Szarmach, A; Winklewski, PJ, 2013)
"CVR is impaired in alert patients with cerebral infarction, although the mean CBF is not reduced, and good collateral flow via the anterior communicating artery in patients with carotid occlusion may be a sign of well-preserved haemodynamic status."2.70Cerebrovascular reactivity to acetazolamide in alert patients with cerebral infarction: usefulness of first-pass radionuclide angiography using 99m Tc-HMPAO in monitoring cerebral haemodynamics. ( Chang, CC; Kanno, H; Kuwana, N; Yamamoto, I, 2001)
"Murine typhus is a systemic febrile illness caused by Rickettsia typhi, a gram-negative, obligate intracellular bacterium."2.50Murine typhus as a cause of cognitive impairment: case report and a review of the literature. ( Bergamo, DF; Carr, SB; Emmanuel, PJ; Ferreira, JA, 2014)
"Acetazolamide treatment did not significantly affect the expression of vascular endothelial growth factor in the tissues studied."1.36Aquaporin-1 expression and angiogenesis in rabbit chronic myocardial ischemia is decreased by acetazolamide. ( Chen, Y; Liang, Y; Liu, W; Lv, X; Ran, X; Sun, J; Wang, B; Wang, H; Zeng, Z; Zhang, K; Zheng, R; Zhou, Q, 2010)
"Normocapnic and chronic hypercapnic COPD patients have the same ventilatory and cerebrovascular carbon dioxide responsiveness irrespective of induced metabolic state."1.31Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD. ( Colier, WN; Folgering, H; Oeseburg, B; van de Ven, MJ; van der Sluijs, MC; Vis, P, 2002)
"We report two cases of idiopathic intracranial hypertension causing chronic daily headache with migrainous features in the absence of associated papilledema."1.29Chronic daily headache with migrainous features due to papilledema-negative idiopathic intracranial hypertension. ( Huff, AL; Hupp, SL; Rothrock, JF, 1996)
"Patients with mixed chronic respiratory acidosis and metabolic alkalosis constitute a common subgroup of patients with chronic obstructive lung disease and carbon dioxide retention; these patients benefit from correction of the metabolic alkalosis."1.26Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease. ( Bear, R; Feldman, R; Goldstein, M; Halperin, M; Hammeke, M; Handelsman, S; Ho, M; Phillipson, E, 1977)

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-199040 (41.67)18.7374
1990's29 (30.21)18.2507
2000's14 (14.58)29.6817
2010's11 (11.46)24.3611
2020's2 (2.08)2.80

Authors

AuthorsStudies
Yang, HL1
Deng, MJ1
Zhang, W1
Huang, S1
Luks, AM1
Hackett, PH1
Imiela, T1
Budaj, A1
Szarmach, A2
Kaszubowski, M1
Sabisz, A1
Frydrychowski, AF2
Halena, G2
Piskunowicz, M1
Dzierzanowski, J1
Studniarek, M1
Szurowska, E1
Winklewski, PJ2
Shah, P1
Liu, X1
Hodgetts, T1
Sii, F1
Bandurski, T1
Carr, SB1
Bergamo, DF1
Emmanuel, PJ1
Ferreira, JA1
Tugcu, B1
Nacaroglu, SA1
Coskun, C1
Kuscu, DY1
Onder, F1
Ranieri, A1
Topa, A1
Cavaliere, M1
De Simone, R1
Yu, H1
Qi, GL1
Wang, J1
Chen, L1
Deng, Z1
Zhao, YS1
Lei, SS1
Zhu, XQ1
Rivera-Ch, M3
Huicho, L2
Bouchet, P2
Richalet, JP4
León-Velarde, F4
Inoue, N1
Harada, M1
Gandhi, MS1
Deshmukh, PA1
Kamalov, G1
Zhao, T1
Zhao, W1
Whaley, JT1
Tichy, JR1
Bhattacharya, SK1
Ahokas, RA1
Sun, Y1
Gerling, IC1
Weber, KT1
Ran, X1
Wang, H1
Chen, Y1
Zeng, Z1
Zhou, Q1
Zheng, R1
Sun, J1
Wang, B1
Lv, X1
Liang, Y1
Zhang, K1
Liu, W1
Pichon, A1
Connes, P1
Quidu, P1
Marchant, D1
Brunet, J1
Levy, BI1
Vilar, J1
Safeukui, I1
Cymbalista, F1
Maignan, M2
Favret, F1
Sood, V1
Rejali, D1
Stocker, J1
Pagliarini, S1
Ahluwalia, H1
Mehta, P1
SCHWARTZ, WB1
RELMAN, AS1
LEAF, A1
BRICAUD, H2
BROUSTET, P2
SCHWAB, M1
TAQUINI, AC1
RONCORONI, AJ1
ARAMENDIA, P1
ROS, AM1
AGNOLETTO, A1
MORESCHI, N1
LONGO, P1
BROMBERG-SZNEK, S1
RAFALOWICZ, A1
PECKENSCHNEIDER, LE1
POKORNY, C1
AGOTE POVEDA, IP1
VILLANUEVA EDO, A1
SEGAL, MS1
ATTINGER, EO1
DUVENCI, J1
PANAYOTOPOULOS, E1
VALTIS, D1
METAXAS, P1
GOULIS, G1
Weil, JV1
García-Gascó, P1
Salame Gamarra, F1
Tenllado Doblas, P1
Chazarra Talens, C1
Rivera, M1
Chirinos, E1
Onnen, I1
Petitjean, O2
Bienvenu, A1
Lasne, F1
Moutereau, S1
Iizuka, T1
Sakai, F1
Ide, T1
Miyakawa, S1
Sato, M1
Yoshii, S1
Collier, DJ1
Nickol, AH1
Milledge, JS1
van Ruiten, HJ1
Collier, CJ1
Swenson, ER1
Datta, A1
Wolff, CB1
Luntz, MH1
Privat, C1
Pham, I1
Macarlupu, JL1
Skatrud, JB1
Berssenbrugge, AD1
Rames, I1
Kristufek, V1
Kerty, E2
Eide, N1
Hørven, I2
Kuwabara, Y3
Ichiya, Y3
Sasaki, M3
Yoshida, T3
Masuda, K3
Akashi, Y2
Fukumura, T2
DeBacker, WA1
Verbraecken, J1
Willemen, M1
Wittesaele, W1
DeCock, W1
Van deHeyning, P1
Fujii, K1
Fukui, M1
Farber, MD1
Lam, S1
Tessler, HH1
Jennings, TJ1
Cross, A1
Rusin, MM1
Yamamoto, N1
Whitcup, SM1
Csaky, KG1
Podgor, MJ1
Chew, EY1
Perry, CH1
Nussenblatt, RB1
Hacein-Bey, L1
Nour, R1
Pile-Spellman, J1
Van Heertum, R1
Esser, PD1
Young, WL1
Kazumata, K1
Tanaka, N1
Ishikawa, T1
Kuroda, S3
Houkin, K1
Mitsumori, K3
Huff, AL1
Hupp, SL1
Rothrock, JF1
Flach, A1
Rho, D1
Gambhir, S1
Inao, S1
Tadokoro, M1
Nishino, M1
Ito, K1
Ishigaki, T1
Kuchiwaki, H1
Yoshida, J1
Grover, S1
Fishman, GA1
Fiscella, RG1
Adelman, AE1
Ficzere, A1
Valikovics, A1
Fülesdi, B1
Juhász, A1
Czuriga, I1
Csiba, L1
Ohnishi, T1
Yano, T1
Nakano, S1
Jinnouchi, S1
Nagamachi, S1
Flores, LI1
Nakahara, H1
Watanabe, K1
Manni, GL1
Centofanti, M1
Napoli, D1
Parisi, V1
Bucci, MG1
Nariai, T1
Senda, M1
Ishii, K1
Wakabayashi, S1
Yokota, T1
Toyama, H1
Matsushima, Y1
Hirakawa, K1
Ulrich, PT1
Kroppenstedt, S1
Heimann, A1
Kempski, O1
Tanaka, A1
Yoshinaga, S1
Nakayama, Y1
Tomonaga, M1
Flach, AJ1
Lorberboym, M1
Lampl, Y1
Kesler, A1
Sadeh, M1
Gadot, N1
Chang, CC1
Kanno, H1
Yamamoto, I1
Kuwana, N1
van de Ven, MJ1
Colier, WN1
van der Sluijs, MC1
Oeseburg, B1
Vis, P1
Folgering, H1
Murakami, M1
Yonehara, T1
Takaki, A1
Fujioka, S1
Hirano, T1
Ushio, Y1
Bear, R1
Goldstein, M1
Phillipson, E1
Ho, M1
Hammeke, M1
Feldman, R1
Handelsman, S1
Halperin, M1
Demailly, P2
Duperre, J1
Wilensky, MC1
Bondoli, A1
De Cosmo, G1
Dordoni, L1
Magalini, SI1
Miller, PD1
Berns, AS1
Epstein, DL1
Grant, WM1
Coe, FL1
Firpo, JJ1
Hollandsworth, DL1
Segil, L1
Canterbury, JM1
Reiss, E1
Clivati, A1
Ciofetti, M1
Cavestri, R1
Longhini, E1
Sacks, W3
Esser, AH3
Sacks, S1
Gelişken, O1
Gelişken, F1
Ozçetin, H1
Takigawa, S2
Kamiyama, H2
Abe, H2
Sakuragi, M2
Motomiya, M2
Nakagawa, T2
Tsuru, M2
Senn, P1
Kopp, B1
Feitel, B1
Abbott, K1
Kaiser, S1
Gerok, W1
Häussinger, D1
Cowen, MA1
Green, MR1
Talarico, P1
Cankosyan, G1
Cox, SN1
Hay, E1
Bird, AC1
Berke, SJ1
Bellows, AR1
Shingleton, BJ1
Richter, CU1
Hutchinson, BT1
Gougoux, A1
Vinay, P1
Zizian, L1
Tejedor, A1
Noel, J1
Patsch, J1
Raptis, S1
Dollinger, H1
Rothenbuchner, G1
Fussgänger, R1
Klör, U1
Pfeiffer, EF1
Dancheva, LD1
Schüren, KP1
Hüttemann, U1
Halpern, SE1
Tubis, M1
Golden, M1
Kunsa, J1
Endow, J1
Walsh, C1
Strachan, I1
Evans, PJ1
Dotti, A1
Mombelloni, P1
Fassio, PG1
Beck, GJ1
Grenard, S1
Weekers, R1
Avasthi, P1
Sharma, SD1
Luthra, MC1
Martin, B1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544]34 participants (Actual)Interventional2012-03-31Completed
Double-blind Randomized Acetazolamide Trial in Normal Pressure Hydrocephalus[NCT04975269]Phase 250 participants (Anticipated)Interventional2022-02-17Recruiting
Hypoventilation and High Altitude Chronic Polycythemia: Acetazolamide as a Possible Treatment[NCT00424970]Phase 455 participants (Anticipated)Interventional2007-01-31Completed
Randomized Controlled Trial of N-acetylcysteine and Acetazolamide in Treatment of Chronic Mountain Sickness[NCT01187108]Phase 1/Phase 285 participants (Actual)Interventional2013-06-30Completed
[NCT00000115]Phase 20 participants Interventional1990-12-31Completed
C-arm Cone Beam CTA and CTP With Acetazolamide Challenge in Aneurysmal Subarachnoid Hemorrhage: Evaluating Predictability for Early Ischemia in Cerebral Vasospasm[NCT03377049]Phase 411 participants (Actual)Interventional2019-07-28Completed
The Effect of Topical Corticosteroids and Topical NSAIDs Perioperatively on IL6 Levels in Aqueous Humor and on Incidence of PCME in Patients With NPDR[NCT04940338]Phase 490 participants (Actual)Interventional2021-05-01Completed
Changes of Macular Vasculature After Uncomplicated Phacoemulsification Surgery Using Optical Coherence Tomography Angiography[NCT04594603]30 participants (Anticipated)Observational [Patient Registry]2021-04-13Recruiting
Brain During Effort : Effects of Hypoxia With Respiratory Patients[NCT02854280]33 participants (Actual)Interventional2013-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Who Develop Delayed Cerebral Vasospasm

Clinical neurological deterioration not attributable to other causes, mores specifically not due to re-bleeding, hydrocephalus, or metabolic changes. (NCT03377049)
Timeframe: Day 1-14 during the hospitalization

InterventionParticipants (Count of Participants)
Acetazolamide Challenge2

Percent Change in Left Hemisphere Brain Imaging Maps

Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour

Interventionpercent change (Mean)
Acetazolamide Challenge19.785

Percent Change in Right Hemisphere Brain Imaging Maps

Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour

Interventionpercent change (Mean)
Acetazolamide Challenge21.659

Relative Percent Change in Cerebral Blood Flow

The data that will be statistically compared is the pre-diamox perfusion in comparison to the post-diamox perfusion. A statistically significant change increase in CBF represents an appropriate response to Diamox. Lack of change in CBF or decrease in CBF could be suggestive of potential for developing vasospasm. (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour

Interventionpercent change (Mean)
Acetazolamide Challenge20.722

Reviews

9 reviews available for acetazolamide and Chronic Disease

ArticleYear
[The preventive effect of four drugs on acute mountain sickness: a Bayesian network meta-analysis].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2021, Nov-12, Volume: 44, Issue:11

    Topics: Acetazolamide; Acute Disease; Altitude; Altitude Sickness; Chronic Disease; Humans; Network Meta-Ana

2021
Medical Conditions and High-Altitude Travel.
    The New England journal of medicine, 2022, Jan-27, Volume: 386, Issue:4

    Topics: Acetazolamide; Altitude; Altitude Sickness; Brain Edema; Chronic Disease; Dexamethasone; Female; Hum

2022
Murine typhus as a cause of cognitive impairment: case report and a review of the literature.
    Pediatric neurology, 2014, Volume: 50, Issue:3

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Brain; Chronic Disease; Cognition Disorders; Diagnosis,

2014
Sleep at high altitude.
    High altitude medicine & biology, 2004,Summer, Volume: 5, Issue:2

    Topics: Acetazolamide; Altitude Sickness; Benzodiazepines; Carbonic Anhydrase Inhibitors; Chronic Disease; H

2004
Treatment of chronic mountain sickness: critical reappraisal of an old problem.
    Respiratory physiology & neurobiology, 2007, Sep-30, Volume: 158, Issue:2-3

    Topics: Acclimatization; Acetazolamide; Altitude; Altitude Sickness; Angiotensin-Converting Enzyme Inhibitor

2007
Effect of sleep state and chemical stimuli on breathing.
    Progress in clinical and biological research, 1983, Volume: 136

    Topics: Acetazolamide; Bicarbonates; Carbon Dioxide; Chronic Disease; Humans; Lung Diseases, Obstructive; Me

1983
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
    Transactions of the American Ophthalmological Society, 1998, Volume: 96

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease;

1998
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
    Transactions of the American Ophthalmological Society, 1998, Volume: 96

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease;

1998
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
    Transactions of the American Ophthalmological Society, 1998, Volume: 96

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease;

1998
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
    Transactions of the American Ophthalmological Society, 1998, Volume: 96

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease;

1998
[A review of glaucoma 1974-1975].
    Archives d'ophtalmologie, 1976, Volume: 36, Issue:3

    Topics: Acetazolamide; Chronic Disease; Diagnosis, Differential; Female; Glaucoma; Guanethidine; Humans; Hyd

1976
[Glaucoma].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1968, Volume: 28, Issue:2

    Topics: Acetazolamide; Angiography; Aqueous Humor; Cataract; Cholinesterase Inhibitors; Chronic Disease; Dex

1968

Trials

20 trials available for acetazolamide and Chronic Disease

ArticleYear
Acetazolamide as Add-on Diuretic Therapy in Exacerbations of Chronic Heart Failure: a Pilot Study.
    Clinical drug investigation, 2017, Volume: 37, Issue:12

    Topics: Acetazolamide; Administration, Intravenous; Aged; Aged, 80 and over; Chronic Disease; Diuretics; Dos

2017
Near-infrared transillumination back scattering sounding--new method to assess brain microcirculation in patients with chronic carotid artery stenosis.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Acetazolamide; Aged; Aged, 80 and over; Blood Volume; Carotid Stenosis; Cerebrovascular Circulation;

2013
Effect of acetazolamide on ventilatory response in subjects with chronic mountain sickness.
    Respiratory physiology & neurobiology, 2008, Aug-31, Volume: 162, Issue:3

    Topics: Acetazolamide; Adult; Altitude Sickness; Analysis of Variance; Anticonvulsants; Carbon Dioxide; Chro

2008
Acetazolamide: a treatment for chronic mountain sickness.
    American journal of respiratory and critical care medicine, 2005, Dec-01, Volume: 172, Issue:11

    Topics: Acetazolamide; Administration, Oral; Adult; Altitude Sickness; Blood Pressure; Carbonic Anhydrase In

2005
Alveolar PCO2 oscillations and ventilation at sea level and at high altitude.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 104, Issue:2

    Topics: Acclimatization; Acetazolamide; Acute Disease; Administration, Inhalation; Altitude; Bicycling; Carb

2008
GLAUCOMA TREATED WITH DARANIDE A CLINICAL TRIAL.
    The British journal of ophthalmology, 1961, Volume: 45, Issue:2

    Topics: Acetazolamide; Aged; Carbonic Anhydrase Inhibitors; Chronic Disease; Dichlorphenamide; Drug Therapy,

1961
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
    American journal of respiratory and critical care medicine, 2008, Jun-15, Volume: 177, Issue:12

    Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu

2008
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
    American journal of respiratory and critical care medicine, 2008, Jun-15, Volume: 177, Issue:12

    Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu

2008
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
    American journal of respiratory and critical care medicine, 2008, Jun-15, Volume: 177, Issue:12

    Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu

2008
Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment.
    American journal of respiratory and critical care medicine, 2008, Jun-15, Volume: 177, Issue:12

    Topics: Acetazolamide; Altitude Sickness; Analysis of Variance; Carbonic Anhydrase Inhibitors; Cardiac Outpu

2008
[Effect of different saluretics on carbohydrate metabolism and blood pressure behavior in diabetics].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1984, Volume: 44, Issue:2

    Topics: Acetazolamide; Aged; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Chronic Disease; Clinic

1984
[A comparison of the cerebrovascular responses to CO2 and Diamox in patients with unilateral occlusive cerebral arteries: a H2(15)O PET study].
    Kaku igaku. The Japanese journal of nuclear medicine, 1995, Volume: 32, Issue:6

    Topics: Acetazolamide; Aged; Carbon Dioxide; Cerebrovascular Circulation; Chronic Disease; Female; Humans; I

1995
Central apnea index decreases after prolonged treatment with acetazolamide.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:1

    Topics: Acetazolamide; Analysis of Variance; Chronic Disease; Female; Humans; Male; Middle Aged; Polysomnogr

1995
[Pre and post operative evaluation of the perfusion reserve by acetazolamide 99mTc-HMPAO SPECT in patients with chronic occlusive cerebral arteries: a comparative study with PET].
    Kaku igaku. The Japanese journal of nuclear medicine, 1994, Volume: 31, Issue:9

    Topics: Acetazolamide; Adult; Aged; Arterial Occlusive Diseases; Cerebral Arterial Diseases; Cerebral Revasc

1994
Reduction of macular oedema by acetazolamide in patients with chronic iridocyclitis: a randomised prospective crossover study.
    The British journal of ophthalmology, 1994, Volume: 78, Issue:1

    Topics: Acetazolamide; Adult; Age Factors; Aged; Chronic Disease; Delayed-Action Preparations; Double-Blind

1994
[Usefulness of change ratio map in 99mTc-HMPAO SPECT with acetazolamide enhancement].
    Kaku igaku. The Japanese journal of nuclear medicine, 1996, Volume: 33, Issue:4

    Topics: Acetazolamide; Aged; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease;

1996
A randomized, masked, cross-over trial of acetazolamide for cystoid macular edema in patients with uveitis.
    Ophthalmology, 1996, Volume: 103, Issue:7

    Topics: Acetazolamide; Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Chronic Disease; Cross-Over S

1996
Efficacy of dorzolamide hydrochloride in the management of chronic cystoid macular edema in patients with retinitis pigmentosa.
    Retina (Philadelphia, Pa.), 1997, Volume: 17, Issue:3

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Carbonic Anhy

1997
Cerebrovascular reactivity in hypertensive patients: a transcranial Doppler study.
    Journal of clinical ultrasound : JCU, 1997, Volume: 25, Issue:7

    Topics: Acetazolamide; Adult; Aorta; Blood Flow Velocity; Cerebral Arteries; Cerebrovascular Circulation; Ch

1997
Hypotensive effects of dorzolamide eyewash in maximal therapy glaucoma patients: a comparative study with oral acetazolamide.
    Acta ophthalmologica Scandinavica. Supplement, 1997, Issue:224

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chronic

1997
Cerebrovascular reactivity to acetazolamide in alert patients with cerebral infarction: usefulness of first-pass radionuclide angiography using 99m Tc-HMPAO in monitoring cerebral haemodynamics.
    Nuclear medicine communications, 2001, Volume: 22, Issue:10

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Carotid Stenosis; Cere

2001
Acetazolamide and thiamine: an ancillary therapy for chronic mental illness.
    Psychiatry research, 1989, Volume: 28, Issue:3

    Topics: Acetazolamide; Adult; Blood Glucose; Chronic Disease; Clinical Trials as Topic; Double-Blind Method;

1989
Acetazolamide and thiamine (A+T): a preliminary report of an ancillary therapy for chronic mental illness.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:1

    Topics: Acetazolamide; Adult; Age Factors; Aged; Aged, 80 and over; Chronic Disease; Clinical Trials as Topi

1988

Other Studies

67 other studies available for acetazolamide and Chronic Disease

ArticleYear
Regional resting state perfusion variability and delayed cerebrovascular uniform reactivity in subjects with chronic carotid artery stenosis.
    Acta biochimica Polonica, 2018, Volume: 65, Issue:1

    Topics: Acetazolamide; Aged; Brain Stem; Carotid Stenosis; Cerebrovascular Circulation; Chronic Disease; Fem

2018
Acetazolamide can cause acute hypercrystalluria.
    BMJ (Clinical research ed.), 2018, 08-06, Volume: 362

    Topics: Acetazolamide; Altitude Sickness; Chronic Disease; Humans; Mountaineering

2018
Chronic Meningitis Complicating Intracranial Hypertension in Neurobrucellosis: A Case Report.
    Seminars in ophthalmology, 2015, Volume: 30, Issue:5-6

    Topics: Acetazolamide; Adult; Anti-Bacterial Agents; Blood Glucose; Brucella; Brucellosis; Central Nervous S

2015
Recurrent epistaxis following stabbing headache responsive to acetazolamide.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35 Suppl 1

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chronic Disease; Epistaxis; Female; Headache Disorders

2014
Aquaporin 4 inhibition decreased synthesis of cytokines by acetazolamide in the hippocampus of rats with pentrazol-induced chronic epilepsy.
    Genetics and molecular research : GMR, 2016, Sep-23, Volume: 15, Issue:3

    Topics: Acetazolamide; Animals; Aquaporin 4; Chronic Disease; Cytokines; Epilepsy; Hippocampus; Kindling, Ne

2016
Effect of perindopril on vasoreactivity in patients with hypertensive chronic cerebrovascular disease. A comparative analysis of different brain structures.
    Arzneimittel-Forschung, 2008, Volume: 58, Issue:7

    Topics: Acetazolamide; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cerebrovascu

2008
Causes and consequences of zinc dyshomeostasis in rats with chronic aldosteronism.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:3

    Topics: Acetazolamide; Aldosterone; Animals; Calcium; Chronic Disease; Disease Models, Animal; Homeostasis;

2008
Aquaporin-1 expression and angiogenesis in rabbit chronic myocardial ischemia is decreased by acetazolamide.
    Heart and vessels, 2010, Volume: 25, Issue:3

    Topics: Acetazolamide; Animals; Aquaporin 1; Capillaries; Carbonic Anhydrase Inhibitors; Chronic Disease; Di

2010
Acetazolamide and chronic hypoxia: effects on haemorheology and pulmonary haemodynamics.
    The European respiratory journal, 2012, Volume: 40, Issue:6

    Topics: Acetazolamide; Altitude Sickness; Animals; Blood Viscosity; Blood Volume; Carbonic Anhydrase Inhibit

2012
A case report of orbital haemorrhage associated with endoscopic sinus surgery and reversible sight loss: a multidisciplinary approach to management.
    Orbit (Amsterdam, Netherlands), 2013, Volume: 32, Issue:1

    Topics: Acetazolamide; Blindness; Chronic Disease; Combined Modality Therapy; Decompression, Surgical; Dexam

2013
Oral administration of a potent carbonic anhydrase inhibitor (diamox). III. Its use as a diuretic in patients with severe congestive heart failure due to cor pulmonale.
    Annals of internal medicine, 1955, Volume: 42, Issue:1

    Topics: Acetazolamide; Administration, Oral; Carbonic Anhydrase Inhibitors; Chronic Disease; Diuretics; Hear

1955
[Acetazolamide in the treatment of chronic pulmonary heart disease].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Oct-30, Volume: 32, Issue:64

    Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease

1956
[Acetazolamide in the treatment of chronic pulmonary heart disease].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Oct-30, Volume: 32, Issue:64

    Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease

1956
[Acetazolamide in the treatment of chronic pulmonary heart disease].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Oct-30, Volume: 32, Issue:64

    Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease

1956
[Acetazolamide in the treatment of chronic pulmonary heart disease].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1956, Oct-30, Volume: 32, Issue:64

    Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease

1956
[Therapy of pulmonary empyema connected with chronic respiratory acidosis].
    Klinische Wochenschrift, 1957, Feb-15, Volume: 35, Issue:4

    Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Aminophylline; Chronic Disease; Empyema; Empyema, Pl

1957
Sensitivity of respiratory center to carbon dioxide in emphysema and cor pulmonale: effects of carbonic anhydrase inhibition.
    American heart journal, 1957, Volume: 54, Issue:3

    Topics: Acetazolamide; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chronic Disease;

1957
[Acetazolamide (diamox) in the treatment of silicosis with severe chronic respiratory insufficiency].
    La Medicina del lavoro, 1957, Volume: 48, Issue:11

    Topics: Acetazolamide; Chronic Disease; Respiratory Insufficiency; Silicosis

1957
[Acetazolamide in therapy of chronic cor pulmonale].
    Minerva medica, 1958, Jan-13, Volume: 49, Issue:3-4

    Topics: Acetazolamide; Chronic Disease; Humans; Pulmonary Heart Disease

1958
[Effects of diamox in cor pulmonale].
    Polski tygodnik lekarski, 1958, Mar-10, Volume: 13, Issue:10

    Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease

1958
Oral diuril; its use in therapy of chronic heart failure.
    The Journal of the Kansas Medical Society, 1958, Volume: 59, Issue:8

    Topics: Acetazolamide; Chlorothiazide; Chronic Disease; Heart Failure

1958
[Acetazolamide in the treatment of chronic cor pulmonale].
    Revista clinica espanola, 1958, May-31, Volume: 69, Issue:4

    Topics: Acetazolamide; Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Heart Disease

1958
Chronic cor pulmonale; its management; notes on the use of chlorothiazide (diuril).
    Journal of the American Geriatrics Society, 1959, Volume: 7, Issue:3

    Topics: Acetazolamide; Chlorothiazide; Chronic Disease; Disease Management; Humans; Pulmonary Heart Disease

1959
[The influence of acetazolamide on patients with chronic respiratory insufficiency].
    Revue medicale de la Suisse romande, 1960, Volume: 80

    Topics: Acetazolamide; Chronic Disease; Leadership; Pulmonary Emphysema; Respiratory Insufficiency

1960
[Complete resolution of chronic hydrocephalus of adult with acetazolamide].
    Medicina clinica, 2005, Apr-09, Volume: 124, Issue:13

    Topics: Acetazolamide; Aged; Brain; Carbonic Anhydrase Inhibitors; Chronic Disease; Cognition Disorders; Fem

2005
Regional cerebral blood flow and cerebrovascular reactivity during chronic stage of stroke-like episodes in MELAS -- implication of neurovascular cellular mechanism.
    Journal of the neurological sciences, 2007, Jun-15, Volume: 257, Issue:1-2

    Topics: Acetazolamide; Adult; Aged; Brain; Carbonic Anhydrases; Cerebral Arteries; Cerebrovascular Circulati

2007
Ocular hemodynamic changes in patients with high-grade carotid occlusive disease and development of chronic ocular ischaemia. II. Clinical findings.
    Acta ophthalmologica Scandinavica, 1995, Volume: 73, Issue:1

    Topics: Acetazolamide; Aged; Aged, 80 and over; Blindness; Blood Flow Velocity; Carotid Artery, Internal; Ca

1995
Time dependency of the acetazolamide effect on cerebral hemodynamics in patients with chronic occlusive cerebral arteries. Early steal phenomenon demonstrated by [15O]H2O positron emission tomography.
    Stroke, 1995, Volume: 26, Issue:10

    Topics: Acetazolamide; Aged; Arterial Occlusive Diseases; Blood Pressure; Brain Ischemia; Carotid Artery, In

1995
Ocular hemodynamic changes in patients with high-grade carotid occlusive disease and development of chronic ocular ischaemia. I. Doppler and dynamic tonometry findings.
    Acta ophthalmologica Scandinavica, 1995, Volume: 73, Issue:1

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Carotid Artery, Internal; Caroti

1995
Adaptive changes of autoregulation in chronic cerebral hypotension with arteriovenous malformations: an acetazolamide-enhanced single-photon emission CT study.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:9

    Topics: Acetazolamide; Adaptation, Physiological; Adolescent; Adult; Blood Pressure; Carbonic Anhydrase Inhi

1995
Dissociation of vasoreactivity to acetazolamide and hypercapnia. Comparative study in patients with chronic occlusive major cerebral artery disease.
    Stroke, 1996, Volume: 27, Issue:11

    Topics: Acetazolamide; Aged; Carbonic Anhydrase Inhibitors; Cerebral Infarction; Cerebrovascular Circulation

1996
Chronic daily headache with migrainous features due to papilledema-negative idiopathic intracranial hypertension.
    Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:6

    Topics: Acetazolamide; Adult; Chronic Disease; Female; Headache; Humans; Intracranial Pressure; Middle Aged;

1996
Acetazolamide treatment of CME in patients with uveitis.
    Ophthalmology, 1996, Volume: 103, Issue:11

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chronic Disease; Humans; Macular Edema; Randomized Con

1996
Acetazolamide treatment of CME in patients with uveitis.
    Ophthalmology, 1996, Volume: 103, Issue:11

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chronic Disease; Humans; Macular Edema; Randomized Con

1996
Comparison of vasodilatory effect of carbon dioxide inhalation and intravenous acetazolamide on brain vasculature using positron emission tomography.
    Neurological research, 1997, Volume: 19, Issue:2

    Topics: Acetazolamide; Administration, Inhalation; Aged; Carbon Dioxide; Cerebrovascular Circulation; Cerebr

1997
Acetazolamide challenge and technetium-99m-ECD versus iodine-123-IMP SPECT in chronic occlusive cerebrovascular disease.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:9

    Topics: Acetazolamide; Aged; Aged, 80 and over; Amphetamines; Cerebrovascular Circulation; Cerebrovascular D

1997
Posthyperventilatory steal response in chronic cerebral hemodynamic stress: a positron emission tomography study.
    Stroke, 1998, Volume: 29, Issue:7

    Topics: Acetazolamide; Administration, Inhalation; Adult; Aged; Blood Volume; Brain; Brain Ischemia; Carbon

1998
Laser-Doppler scanning of local cerebral blood flow and reserve capacity and testing of motor and memory functions in a chronic 2-vessel occlusion model in rats.
    Stroke, 1998, Volume: 29, Issue:11

    Topics: Acetazolamide; Animals; Anticonvulsants; Arterial Occlusive Diseases; Behavior, Animal; Blood Pressu

1998
Cerebral blood flow and the response to acetazolamide during the acute, subacute, and chronic stages of aneurysmal subarachnoid hemorrhage.
    Neurologia medico-chirurgica, 1998, Volume: 38, Issue:10

    Topics: Acetazolamide; Acute Disease; Adult; Aged; Aged, 80 and over; Cerebrovascular Circulation; Chronic D

1998
Benign intracranial hypertension: correlation of cerebral blood flow with disease severity.
    Clinical neurology and neurosurgery, 2001, Volume: 103, Issue:1

    Topics: Acetazolamide; Adult; Brain; Cerebrovascular Circulation; Chronic Disease; Diuretics; Female; Humans

2001
Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD.
    Chest, 2002, Volume: 121, Issue:2

    Topics: Acetazolamide; Administration, Oral; Alkalosis; Blood Volume; Carbon Dioxide; Cerebrovascular Circul

2002
Evaluation of delayed appearance of acetazolamide effect in patients with chronic cerebrovascular ischemic disease: feasibility and usefulness of SPECT method using triple injection of ECD.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2002, Volume: 43, Issue:5

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Brain Ischemia; Carotid Artery, Internal; Carotid Ste

2002
Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease.
    Canadian Medical Association journal, 1977, Oct-22, Volume: 117, Issue:8

    Topics: Acetazolamide; Acidosis, Respiratory; Aged; Alkalosis; Ammonium Chloride; Bicarbonates; Blood Gas An

1977
Curent concepts in primary angle-closure glaucoma.
    Annals of ophthalmology, 1977, Volume: 9, Issue:8

    Topics: Acetazolamide; Acute Disease; Chronic Disease; Glaucoma; Glycerol; Humans; Mannitol; Moxisylyte

1977
[Acetazolamide in respiratory insufficiency].
    Recenti progressi in medicina, 1979, Volume: 67, Issue:3

    Topics: Acetazolamide; Acid-Base Imbalance; Acute Disease; Brain Injuries; Chronic Disease; Humans; Hypercap

1979
Acute metabolic alkalosis perpetuating hypercarbia. A role for acetazolamide in chronic obstructive pulmonary disease.
    JAMA, 1977, Nov-28, Volume: 238, Issue:22

    Topics: Acetazolamide; Aged; Alkalosis; Bicarbonates; Carbon Dioxide; Chronic Disease; Diuretics; Female; He

1977
Carbonic anhydrase inhibitor side effects. Serum chemical analysis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1977, Volume: 95, Issue:8

    Topics: Acetazolamide; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Chronic Disease; Glaucom

1977
Effect of acute and chronic metabolic acidosis on serum immunoreactive parathyroid hormone in man.
    Kidney international, 1975, Volume: 8, Issue:4

    Topics: Acetazolamide; Acidosis; Acute Disease; Ammonium Chloride; Calcium; Chronic Disease; Female; Glomeru

1975
Cerebral vascular responsiveness in chronic hypercapnia.
    Chest, 1992, Volume: 102, Issue:1

    Topics: Acetazolamide; Aged; Blood Flow Velocity; Cerebral Arteries; Cerebrovascular Circulation; Chronic Di

1992
Inhibition of pyruvate dehydrogenase complex (PDHC) by antipsychotic drugs.
    Biological psychiatry, 1991, Jan-15, Volume: 29, Issue:2

    Topics: Acetazolamide; Ambulatory Care; Animals; Brain; Cattle; Chronic Disease; Drug Therapy, Combination;

1991
Treatment of chronic macular oedema with low dosage acetazolamide.
    Bulletin de la Societe belge d'ophtalmologie, 1990, Volume: 238

    Topics: Acetazolamide; Aged; Chronic Disease; Female; Humans; Macular Edema; Male; Middle Aged

1990
[Diagnosis of hemodynamic compromise in patients with chronic cerebral ischemia; the detection of impaired vasodilatory capacity with 133Xe SPECT and acetazolamide (Diamox) test].
    No shinkei geka. Neurological surgery, 1990, Volume: 18, Issue:2

    Topics: Acetazolamide; Adult; Aged; Blood Pressure; Brain Ischemia; Cerebral Revascularization; Cerebrovascu

1990
[Nd:YAG laser synechiolysis in glaucoma due to iridocorneal angle synechiae].
    Klinische Monatsblatter fur Augenheilkunde, 1990, Volume: 196, Issue:4

    Topics: Acetazolamide; Aged; Aged, 80 and over; Chronic Disease; Combined Modality Therapy; Female; Follow-U

1990
[Diagnosis of hemodynamic compromise in patients with chronic cerebral ischemia; measurement of cerebral blood volume (CBV) with 99mTc-RBC SPECT].
    No shinkei geka. Neurological surgery, 1990, Volume: 18, Issue:3

    Topics: Acetazolamide; Adult; Aged; Blood Volume; Brain Ischemia; Cerebrovascular Circulation; Chronic Disea

1990
Ammonia and glutamine metabolism in human liver slices: new aspects on the pathogenesis of hyperammonaemia in chronic liver disease.
    European journal of clinical investigation, 1988, Volume: 18, Issue:5

    Topics: Acetazolamide; Ammonia; Bicarbonates; Chronic Disease; Glutamine; Humans; Liver; Liver Diseases; Ure

1988
Treatment of chronic macular edema with acetazolamide.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1988, Volume: 106, Issue:9

    Topics: Acetazolamide; Chronic Disease; Dose-Response Relationship, Drug; Eye Diseases; Fluorescein Angiogra

1988
Chronic and recurrent choroidal detachment after glaucoma filtering surgery.
    Ophthalmology, 1987, Volume: 94, Issue:2

    Topics: Acetazolamide; Aged; Aged, 80 and over; Choroid; Chronic Disease; Female; Glaucoma, Open-Angle; Huma

1987
Effect of acetazolamide on renal metabolism and ammoniagenesis in the dog.
    Kidney international, 1987, Volume: 31, Issue:6

    Topics: Acetazolamide; Acidosis; Ammonium Chloride; Animals; Chronic Disease; Citrates; Citric Acid; Dogs; G

1987
[Blood oxygen pressure as a criterion of pulmonary function and therapy].
    Wiener medizinische Wochenschrift (1946), 1971, Jun-19, Volume: 121, Issue:25

    Topics: Acetazolamide; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Bacterial Agents; A

1971
Effect of acetazolamide on the insulin response to intravenous administration of secretin.
    Nutrition and metabolism, 1974, Volume: 16, Issue:2

    Topics: Acetazolamide; Antigens; Bicarbonates; Blood Glucose; Chronic Disease; Drug Synergism; Duodenum; Fat

1974
[A new approach in determining the indications for surgical intervention in glaucoma].
    Oftalmologicheskii zhurnal, 1972, Volume: 27, Issue:8

    Topics: Acetazolamide; Adult; Aged; Chronic Disease; Glaucoma; Humans; Intraocular Pressure; Methods; Middle

1972
[Cardiac therapy of chronic bronchitis (author's transl)].
    Medizinische Klinik, 1974, Jan-04, Volume: 69, Issue:1

    Topics: Acetazolamide; Bloodletting; Bronchitis; Chronic Disease; Digitalis Glycosides; Diuretics; Hemodynam

1974
99m TPAC, a new renal scanning agent. II. Evaluation in humans.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1972, Volume: 13, Issue:10

    Topics: Acetazolamide; Adenocarcinoma; Adolescent; Adult; Arteriosclerosis; Child; Chronic Disease; Diabetic

1972
A method of determining the site of outflow resistance.
    Transactions of the ophthalmological societies of the United Kingdom, 1970, Volume: 89

    Topics: Acetazolamide; Aqueous Humor; Chronic Disease; Ciliary Body; Cornea

1970
Modern problems in glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1971, Volume: 91

    Topics: Acetazolamide; Acute Disease; Aged; Bicarbonates; Chronic Disease; Ciliary Body; Dichlorphenamide; E

1971
[Evaluation of the effects of various diuretics in chronic lung diseases with chronic respiratory insufficiency (CRI)].
    Giornale di clinica medica, 1969, Volume: 50, Issue:9

    Topics: Acetazolamide; Amides; Chronic Disease; Clopamide; Diuretics; Humans; Hydrogen-Ion Concentration; Lu

1969
Intensive respiratory care: advances in management of patients with obstructive pulmonary disease.
    Journal of the American Geriatrics Society, 1970, Volume: 18, Issue:1

    Topics: Acetazolamide; Blood; Blood Gas Analysis; Carbon Dioxide; Chronic Disease; Humans; Hydrogen-Ion Conc

1970
[Treatment of open angle glaucoma (synonym: chronic simple glaucoma)].
    Annales d'oculistique, 1968, Volume: 201, Issue:1

    Topics: Acetazolamide; Acetylcholine; Carbonic Anhydrase Inhibitors; Chronic Disease; Dichlorphenamide; Echo

1968
Influence of drugs on aqueous flow in chronic simple glaucoma.
    International surgery, 1968, Volume: 49, Issue:6

    Topics: Acetazolamide; Adult; Aqueous Humor; Chronic Disease; Female; Glaucoma; Glycerol; Humans; Intraocula

1968
Infiltration of the iris in chronic lymphatic leukaemia.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:10

    Topics: Acetazolamide; Chlorambucil; Chronic Disease; Glaucoma; Humans; Intraocular Pressure; Iris; Leukemia

1968