acetazolamide has been researched along with Channelopathies in 4 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Channelopathies: A variety of neuromuscular conditions resulting from MUTATIONS in ION CHANNELS manifesting as episodes of EPILEPSY; HEADACHE DISORDERS; and DYSKINESIAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypokalaemic periodic paralysis (hypoPP) is the archetypal skeletal muscle channelopathy caused by dysfunction of one of two sarcolemmal ion channels, either the sodium channel Nav1." | 2.46 | Muscle channelopathies: does the predicted channel gating pore offer new treatment insights for hypokalaemic periodic paralysis? ( Hanna, MG; Matthews, E, 2010) |
| "A presumed diagnosis of episodic ataxia type 2 was made and she became attack free on acetazolamide without recurrence." | 1.51 | A sleep modulated Channelopathy: a novel CACNA1A pathogenic variant identified in episodic Ataxia type 2 and a potential link to sleep alleviated migraine. ( Ahuja, AS; Atwal, PS; Rozen, TD, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahuja, AS | 1 |
| Rozen, TD | 1 |
| Atwal, PS | 1 |
| Cramer, SW | 1 |
| Popa, LS | 1 |
| Carter, RE | 1 |
| Chen, G | 1 |
| Ebner, TJ | 1 |
| Matthews, E | 1 |
| Hanna, MG | 1 |
| Platt, D | 1 |
| Griggs, RC | 1 |
1 review available for acetazolamide and Channelopathies
| Article | Year |
|---|---|
Muscle channelopathies: does the predicted channel gating pore offer new treatment insights for hypokalaemic periodic paralysis?
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Channelopathies; Humans; | 2010 |
3 other studies available for acetazolamide and Channelopathies
| Article | Year |
|---|---|
A sleep modulated Channelopathy: a novel CACNA1A pathogenic variant identified in episodic Ataxia type 2 and a potential link to sleep alleviated migraine.
Topics: Acetazolamide; Adult; Ataxia; Calcium Channels; Carbonic Anhydrase Inhibitors; Channelopathies; Codo | 2019 |
Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Benzeneacetamides; Calcium Channels, N-Type; Cerebral Corte | 2015 |
Use of acetazolamide in sulfonamide-allergic patients with neurologic channelopathies.
Topics: Acetazolamide; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Channelopathies; Drug Hypersensitiv | 2012 |