acetazolamide has been researched along with Cerebrospinal Fluid Rhinorrhea in 14 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Cerebrospinal Fluid Rhinorrhea: Discharge of cerebrospinal fluid through the nose. Common etiologies include trauma, neoplasms, and prior surgery, although the condition may occur spontaneously. (Otolaryngol Head Neck Surg 1997 Apr;116(4):442-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide has become a standard treatment for cerebrospinal fluid (CSF) leaks associated with intracranial hypertension." | 3.79 | Acetazolamide for high intracranial pressure cerebrospinal fluid leaks. ( Chaaban, MR; Illing, E; Riley, KO; Woodworth, BA, 2013) |
| "Spontaneous CSF rhinorrhea associated with IIH represents a challenging clinical entity, with an increased risk of recurrence compared to CSF leaks because of other causes." | 2.58 | Long-term management and outcomes after repair of cerebrospinal fluid rhinorrhea related to idiopathic intracranial hypertension. ( Schuman, TA; Senior, BA, 2018) |
| "In the authors' cohort, morbid obesity was statistically associated with the need for postoperative CSF diversion." | 1.56 | Surgical outcomes of the endonasal endoscopic approach within a standardized management protocol for repair of spontaneous cerebrospinal fluid rhinorrhea. ( Carrau, RL; Hardesty, DA; Kreatsoulas, DC; Otto, BA; Prevedello, DM; Shah, VS, 2020) |
| "Cases with a diagnosis of CSF rhinorrhea discharged after conservative management but required skull base repair for recurrence of CSF rhinorrhea or meningitis were included in the study between periods 2000 and July 2010." | 1.37 | CSF rhinorrhea-feasibility of conservative management in children. ( Francis, AA; Mohindra, S; Yadav, JS, 2011) |
| "Acetazolamide was used in nine patients, whereas six patients underwent VPS placement for elevated ICP management." | 1.36 | Spontaneous CSF leaks: factors predictive of additional interventions. ( Batra, PS; Benninger, MS; Luong, A; Rajasekaran, K; Seth, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Kreatsoulas, DC | 1 |
| Shah, VS | 1 |
| Otto, BA | 1 |
| Carrau, RL | 1 |
| Prevedello, DM | 1 |
| Hardesty, DA | 1 |
| Bujoreanu, I | 1 |
| Ferguson, M | 1 |
| Saleh, H | 1 |
| McCormick, JP | 1 |
| Tilak, A | 2 |
| Lampkin, HB | 1 |
| Thompson, HM | 1 |
| Miller, PL | 1 |
| West, JM | 1 |
| Cho, DY | 2 |
| Riley, KO | 3 |
| Grayson, JW | 1 |
| Woodworth, BA | 3 |
| Teachey, W | 1 |
| Grayson, J | 1 |
| Schuman, TA | 1 |
| Senior, BA | 1 |
| Tilak, AM | 1 |
| Koehn, H | 2 |
| Mattos, J | 1 |
| Payne, SC | 2 |
| Geltzeiler, M | 1 |
| Carrau, R | 1 |
| Chandra, R | 1 |
| Palmer, J | 1 |
| Schlosser, R | 1 |
| Smith, T | 1 |
| Wise, S | 1 |
| Woodworth, B | 1 |
| Mattos, JL | 1 |
| Chaaban, MR | 1 |
| Illing, E | 1 |
| Abrishamkar, S | 1 |
| Khalighinejad, N | 1 |
| Moein, P | 1 |
| Yadav, JS | 1 |
| Mohindra, S | 1 |
| Francis, AA | 1 |
| Seth, R | 1 |
| Rajasekaran, K | 1 |
| Luong, A | 1 |
| Benninger, MS | 1 |
| Batra, PS | 1 |
| Brun, A | 1 |
| Julier, I | 1 |
| Sirvain, S | 1 |
| Fraisse, T | 1 |
| Kalamarides, M | 1 |
| Grayeli, AB | 1 |
| Bouccara, D | 1 |
| Redondo, A | 1 |
| Rey, A | 1 |
| Sterkers, O | 1 |
2 reviews available for acetazolamide and Cerebrospinal Fluid Rhinorrhea
| Article | Year |
|---|---|
Intervention for elevated intracranial pressure improves success rate after repair of spontaneous cerebrospinal fluid leaks.
Topics: Acetazolamide; Anticonvulsants; Cerebrospinal Fluid Rhinorrhea; Cerebrospinal Fluid Shunts; Combined | 2017 |
Long-term management and outcomes after repair of cerebrospinal fluid rhinorrhea related to idiopathic intracranial hypertension.
Topics: Acetazolamide; Cerebrospinal Fluid Rhinorrhea; Cerebrospinal Fluid Shunts; Combined Modality Therapy | 2018 |
1 trial available for acetazolamide and Cerebrospinal Fluid Rhinorrhea
| Article | Year |
|---|---|
Analysing the effect of early acetazolamide administration on patients with a high risk of permanent cerebrospinal fluid leakage.
Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Leak; Cerebrosp | 2013 |
11 other studies available for acetazolamide and Cerebrospinal Fluid Rhinorrhea
| Article | Year |
|---|---|
Surgical outcomes of the endonasal endoscopic approach within a standardized management protocol for repair of spontaneous cerebrospinal fluid rhinorrhea.
Topics: Acetazolamide; Adolescent; Adult; Aged; Cerebrospinal Fluid Rhinorrhea; Craniotomy; Diuretics; Encep | 2020 |
Chemotherapy associated dural sinus thrombosis presenting as a cerebrospinal fluid leak.
Topics: Acetazolamide; Antineoplastic Agents; Breast Neoplasms; Carboplatin; Cerebrospinal Fluid Rhinorrhea; | 2020 |
An Expedited Intracranial Pressure Monitoring Protocol Following Spontaneous CSF Leak Repair.
Topics: Acetazolamide; Adult; Aged; Cerebrospinal Fluid Rhinorrhea; Clinical Protocols; Diuretics; Endoscopy | 2021 |
Preoperative management of spontaneous cerebrospinal fluid rhinorrhea with acetazolamide.
Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Leak; Cerebrospinal Fluid R | 2019 |
Management of spontaneous cerebrospinal fluid leaks.
Topics: Acetazolamide; Cerebrospinal Fluid Leak; Cerebrospinal Fluid Rhinorrhea; Humans; Intracranial Hypert | 2019 |
Re: Management of spontaneous cerebrospinal fluid leaks.
Topics: Acetazolamide; Cerebrospinal Fluid Leak; Cerebrospinal Fluid Rhinorrhea; Humans; Intracranial Hypert | 2019 |
Acetazolamide for high intracranial pressure cerebrospinal fluid leaks.
Topics: Acetazolamide; Administration, Oral; Adult; Aged; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid | 2013 |
CSF rhinorrhea-feasibility of conservative management in children.
Topics: Acetazolamide; Adolescent; Cerebrospinal Fluid Rhinorrhea; Child; Child, Preschool; Cohort Studies; | 2011 |
Spontaneous CSF leaks: factors predictive of additional interventions.
Topics: Acetazolamide; Aged; Algorithms; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Rhinorrhea; Combi | 2010 |
[Brain lesion].
Topics: Acetazolamide; Aged; Cerebrospinal Fluid Rhinorrhea; Confusion; Headache; Humans; Male; Pituitary Ne | 2012 |
Opening cerebrospinal fluid pressure guides the management of cerebrospinal fluid leakage after acoustic neuroma surgery.
Topics: Acetazolamide; Adult; Aged; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Rhinorrhea; Cranial Fo | 2004 |