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acetazolamide and Cerebral Cryptococcosis

acetazolamide has been researched along with Cerebral Cryptococcosis in 9 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"We conducted a trial of oral acetazolamide for the treatment of cryptococcal meningitis in 22 Thai adults with headache and an opening cerebrospinal fluid pressure of >/=200 mm H(2)0."5.10A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis. ( Chasombat, S; Chierakul, W; Lalloo, DG; Maek-A-Nantawat, W; Newton, PN; Phonrat, B; Pitisuttithum, P; Rajanuwong, A; Short, JM; Teaunadi, R; Thai, le H; Tip, NQ; White, NJ, 2002)
"Cryptococcal meningitis is a severe fungal infection that occurs primarily in the setting of advanced immunodeficiency and remains a major cause of HIV-related deaths worldwide."2.58Treatment for HIV-associated cryptococcal meningitis. ( Eshun-Wilson, I; Ford, N; Jarvis, JN; Li, T; Rouse, B; Shapiro, AE; Tenforde, MW, 2018)
" The optimal dosing of AmB remains unclear."2.44Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings. ( Dedicoat, M; Dlamini, S; Paul, N; Sloan, D, 2008)
" The objective of the study was to investigate the efficacy of acetazolamide (AZA), candesartan (CAN), and triciribine (TCBN), in combination with the antifungal fluconazole, on C."1.91A multi-arm, parallel, preclinical study investigating the potential benefits of acetazolamide, candesartan, and triciribine in combination with fluconazole for the treatment of cryptococcal meningoencephalitis. ( Alanazi, AH; Chastain, DB; Franco-Paredes, C; Henao-Martínez, AF; Lin, X; Narayanan, SP; Parvathagiri, V; Rudraraju, M; Shan, S; Somanath, PR, 2023)
"After he was diagnosed as cryptococcal meningitis using the microscopy, cryptococcal antigen detection and culture of cerebrospinal fluid, treatment with amphotericin-B and fluconazole was started."1.29[A case of AIDS with intractable cryptococcal meningitis]. ( Imae, N; Konishi, M; Maeda, K; Masutani, T; Migita, T; Mikasa, K; Mori, K; Narita, N; Sano, R; Sawaki, M; Yamanaka, T; Yoshioka, A, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Alanazi, AH1
Chastain, DB1
Rudraraju, M1
Parvathagiri, V1
Shan, S1
Lin, X1
Henao-Martínez, AF1
Franco-Paredes, C1
Narayanan, SP1
Somanath, PR1
Tenforde, MW1
Shapiro, AE1
Rouse, B1
Jarvis, JN1
Li, T1
Eshun-Wilson, I1
Ford, N1
Sloan, D1
Dlamini, S1
Paul, N1
Dedicoat, M1
Newton, PN1
Thai, le H1
Tip, NQ1
Short, JM1
Chierakul, W1
Rajanuwong, A1
Pitisuttithum, P1
Chasombat, S1
Phonrat, B1
Maek-A-Nantawat, W1
Teaunadi, R1
Lalloo, DG1
White, NJ1
Patel, S1
Lederman, E1
Wallace, M1
Lane, M1
McBride, J1
Archer, J1
Orem, J1
Tindyebwa, L1
Twinoweitu, O1
Mukasa, B1
Tomberland, M1
Mbidde, EK1
Konishi, M1
Migita, T1
Mori, K1
Imae, N1
Yamanaka, T1
Maeda, K1
Mikasa, K1
Sawaki, M1
Yoshioka, A1
Sano, R1
Masutani, T1
Narita, N1
Ferreira, RC1
Phan, G1
Bateman, JB1

Reviews

2 reviews available for acetazolamide and Cerebral Cryptococcosis

ArticleYear
Treatment for HIV-associated cryptococcal meningitis.
    The Cochrane database of systematic reviews, 2018, 07-25, Volume: 7

    Topics: Acetazolamide; Acute Disease; Adult; Amphotericin B; Antifungal Agents; Developing Countries; Drug A

2018
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings.
    The Cochrane database of systematic reviews, 2008, Oct-08, Issue:4

    Topics: Acetazolamide; Acute Disease; Adult; Amphotericin B; Antifungal Agents; Antihypertensive Agents; Dev

2008

Trials

2 trials available for acetazolamide and Cerebral Cryptococcosis

ArticleYear
A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Sep-15, Volume: 35, Issue:6

    Topics: Acetazolamide; Acidosis; Administration, Oral; Adult; Amphotericin B; Antifungal Agents; Diuretics;

2002
Feasibility study of serial lumbar puncture and acetazolamide combination in the management of elevated cerebrospinal fluid pressure in AIDS patients with cryptococcal meningitis in Uganda.
    Tropical doctor, 2005, Volume: 35, Issue:1

    Topics: Acetazolamide; Adult; AIDS-Related Opportunistic Infections; Carbonic Anhydrase Inhibitors; Cerebros

2005

Other Studies

5 other studies available for acetazolamide and Cerebral Cryptococcosis

ArticleYear
A multi-arm, parallel, preclinical study investigating the potential benefits of acetazolamide, candesartan, and triciribine in combination with fluconazole for the treatment of cryptococcal meningoencephalitis.
    European journal of pharmacology, 2023, Dec-05, Volume: 960

    Topics: Acetazolamide; Animals; Antifungal Agents; Cryptococcus neoformans; Fluconazole; Humans; Meningitis,

2023
Acetazolamide therapy and intracranial pressure.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Feb-15, Volume: 36, Issue:4

    Topics: Acetazolamide; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Humans; Intracranial

2003
Steroid responsive late deterioration in Cryptococcus neoformans variety gattii meningitis.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Acetazolamide; Adult; Amphotericin B; Antifungal Agents; Arachnoiditis; Cerebral Infarction; Dexamet

2004
[A case of AIDS with intractable cryptococcal meningitis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1996, Volume: 70, Issue:7

    Topics: Acetazolamide; Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Amphotericin B; A

1996
Favorable visual outcome in cryptococcal meningitis.
    American journal of ophthalmology, 1997, Volume: 124, Issue:4

    Topics: Acetazolamide; Adolescent; Anti-Inflammatory Agents; Antifungal Agents; Dexamethasone; Female; Fluco

1997