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acetazolamide and Cerebral Arterial Diseases

acetazolamide has been researched along with Cerebral Arterial Diseases in 22 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Cerebral Arterial Diseases: Pathological conditions of intracranial ARTERIES supplying the CEREBRUM. These diseases often are due to abnormalities or pathological processes in the ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; and POSTERIOR CEREBRAL ARTERY.

Research Excerpts

ExcerptRelevanceReference
" The ratio of cerebral blood volume to cerebral blood flow (CBV/CBF) and vasoreactivity in response to hypercapnia (%CBF(hypercapnia)) and acetazolamide (ACZ) stress (%CBF(ACZ)) were measured to evaluate circulatory reserve."3.73Relationship between cerebral circulatory reserve and oxygen extraction fraction in patients with major cerebral artery occlusive disease: a positron emission tomography study. ( Hatazawa, J; Moroi, J; Nagata, K; Sato, M; Shimosegawa, E; Suzuki, A; Yata, K, 2006)
"Change in acetazolamide reactivity might be a good predictor for brain atrophy in cerebral artery occlusive disease."3.73Changes in brain volume 2 years after extracranial-intracranial bypass surgery: A preliminary subanalysis of the Japanese EC-IC trial. ( Fujimoto, S; Gotoh, S; Ibayashi, S; Iida, M; Inoue, T; Jinnouchi, J; Okada, Y; Toyoda, K; Yasumori, K, 2006)
"Twelve patients with symptomatic MCA stenosis were recruited."1.40Evaluation of cerebrovascular reserve using xenon-enhanced CT scanning in patients with symptomatic middle cerebral artery stenosis. ( Cao, W; Cheng, X; Dong, Q; Li, H; Wang, L; Zhang, X, 2014)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (31.82)18.2507
2000's12 (54.55)29.6817
2010's2 (9.09)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Fujimoto, K1
Uwano, I1
Sasaki, M2
Oshida, S1
Tsutsui, S1
Yanagihara, W1
Fujiwara, S2
Kobayashi, M3
Kubo, Y2
Yoshida, K2
Terasaki, K3
Ogasawara, K3
Cao, W1
Cheng, X1
Li, H1
Wang, L1
Zhang, X1
Dong, Q1
Kuroda, H1
Suzuki, T1
Chida, K1
Aso, K1
Ogawa, A2
Yamauchi, H3
Okazawa, H3
Kishibe, Y1
Sugimoto, K3
Takahashi, M2
Fujimoto, S2
Hasegawa, Y3
Yokota, C2
Tagaya, M1
Hayashida, K2
Yamaguchi, T3
Minematsu, K3
Yukawa, H1
Mikami, C1
Konno, H1
Inoue, T2
Toyoda, H1
Fujibayashi, Y1
Yonekura, Y2
Harada, M1
Uno, M1
Yoneda, K1
Hori, A1
Nishitani, H1
Matsuda, T1
Ito, H1
Inoue, K1
Goto, R1
Kinomura, S1
Sato, T1
Kaneta, T1
Sato, K1
Fukuda, H1
Yata, K1
Suzuki, A1
Hatazawa, J1
Shimosegawa, E1
Nagata, K1
Sato, M1
Moroi, J1
Jinnouchi, J1
Toyoda, K1
Gotoh, S1
Yasumori, K1
Ibayashi, S1
Iida, M1
Okada, Y1
Nemoto, EM1
Yonas, H1
Pindzola, RR1
Kuwabara, H1
Sashin, D1
Chang, Y1
Jovin, T1
Kuwabara, Y1
Ichiya, Y1
Akashi, Y1
Yoshida, T1
Fukumura, T1
Masuda, K1
Fujii, K1
Fukui, M1
Mandai, K2
Sueyoshi, K2
Fukunaga, R2
Nukada, M2
Ohtani, F1
Araki, Y1
Tsukaguchi, I2
Abe, H1
Hirano, T1
Tanaka, Y1
Matsumoto, M1
Kamada, T1
Takeuchi, R1
Matsuda, H1
Sakahara, H1
Konishi, J1
Weller, M1
Dichgans, J1
Klockgether, T1
Detre, JA1
Samuels, OB1
Alsop, DC1
Gonzalez-At, JB1
Kasner, SE1
Raps, EC1
Cao, B1
Arbab, AS1
Aoki, S1
Toyama, K1
Miyazawa, N1
Kumagai, H1
Umeda, T1
Arai, T1
Araki, T1
Kabasawa, H1
Takahashi, Y1

Trials

7 trials available for acetazolamide and Cerebral Arterial Diseases

ArticleYear
Reduced blood flow response to acetazolamide reflects pre-existing vasodilation and decreased oxygen metabolism in major cerebral arterial occlusive disease.
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:10

    Topics: Acetazolamide; Arterial Occlusive Diseases; Blood Flow Velocity; Brain; Carotid Artery Thrombosis; C

2002
Differences in vasodilatory capacity and changes in cerebral blood flow induced by acetazolamide in patients with cerebrovascular disease.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:9

    Topics: Acetazolamide; Adult; Aged; Arterial Occlusive Diseases; Blood Flow Velocity; Brain; Cerebral Arteri

2003
Relationship between vasodilatation and cerebral blood flow increase in impaired hemodynamics: a PET study with the acetazolamide test in cerebrovascular disease.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:12

    Topics: Acetazolamide; Aged; Arterial Occlusive Diseases; Brain; Cerebral Arterial Diseases; Cerebrovascular

2003
Correlation between flow-sensitive alternating inversion recovery perfusion imaging with different inversion times and cerebral flow reserve evaluated by single-photon-emission computed tomography.
    Neuroradiology, 2004, Volume: 46, Issue:8

    Topics: Acetazolamide; Aged; Blood Circulation Time; Brain Ischemia; Cerebral Arterial Diseases; Cerebrovasc

2004
Error analysis of measured cerebral vascular response to acetazolamide stress by I-123-IMP autoradiographic method with single photon emission computed tomography: errors due to distribution volume of I-123-IMP.
    Annals of nuclear medicine, 2004, Volume: 18, Issue:3

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Autoradiography; Brain; Cerebral Arterial Diseases; C

2004
[Pre and post operative evaluation of the perfusion reserve by acetazolamide 99mTc-HMPAO SPECT in patients with chronic occlusive cerebral arteries: a comparative study with PET].
    Kaku igaku. The Japanese journal of nuclear medicine, 1994, Volume: 31, Issue:9

    Topics: Acetazolamide; Adult; Aged; Arterial Occlusive Diseases; Cerebral Arterial Diseases; Cerebral Revasc

1994
Noninvasive quantitative measurements of regional cerebral blood flow using technetium-99m-L,L-ECD SPECT activated with acetazolamide: quantification analysis by equal-volume-split 99mTc-ECD consecutive SPECT method.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:10

    Topics: Acetazolamide; Adult; Aged; Arterial Occlusive Diseases; Carotid Stenosis; Cerebral Arterial Disease

1997

Other Studies

15 other studies available for acetazolamide and Cerebral Arterial Diseases

ArticleYear
Acetazolamide-Loaded Dynamic 7T MR Quantitative Susceptibility Mapping in Major Cerebral Artery Steno-Occlusive Disease: Comparison with PET.
    AJNR. American journal of neuroradiology, 2020, Volume: 41, Issue:5

    Topics: Acetazolamide; Adult; Aged; Brain; Cerebral Arterial Diseases; Cerebrovascular Circulation; Female;

2020
Evaluation of cerebrovascular reserve using xenon-enhanced CT scanning in patients with symptomatic middle cerebral artery stenosis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:2

    Topics: Acetazolamide; Cardiovascular Agents; Cerebral Arterial Diseases; Cerebral Cortex; Cerebrovascular C

2014
Accuracy of central benzodiazepine receptor binding potential/cerebral blood flow SPECT imaging for detecting misery perfusion in patients with unilateral major cerebral artery occlusive diseases: comparison with cerebrovascular reactivity to acetazolamid
    Clinical nuclear medicine, 2012, Volume: 37, Issue:3

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Area Under Curve; Arterial Occlusive Diseases; Carbon

2012
Acetazolamide challenge test using semiquantitative 123 I-IMP SPECT for detection of cerebral misery perfusion.
    Journal of the neurological sciences, 2002, Dec-15, Volume: 205, Issue:1

    Topics: Acetazolamide; Aged; Arterial Occlusive Diseases; Blood Volume; Carbonic Anhydrase Inhibitors; Cereb

2002
Prediction and monitoring of cerebral hyperperfusion after carotid endarterectomy by using single-photon emission computerized tomography scanning.
    Journal of neurosurgery, 2003, Volume: 99, Issue:3

    Topics: Acetazolamide; Aged; Anticonvulsants; Cerebral Arterial Diseases; Cerebrovascular Circulation; Endar

2003
Relationship between cerebral circulatory reserve and oxygen extraction fraction in patients with major cerebral artery occlusive disease: a positron emission tomography study.
    Stroke, 2006, Volume: 37, Issue:2

    Topics: Acetazolamide; Adult; Aged; Brain; Cerebral Arterial Diseases; Cerebrovascular Circulation; Cerebrov

2006
Changes in brain volume 2 years after extracranial-intracranial bypass surgery: A preliminary subanalysis of the Japanese EC-IC trial.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 22, Issue:2-3

    Topics: Acetazolamide; Aged; Atrophy; Brain; Brain Ischemia; Cerebral Arterial Diseases; Cerebral Revascular

2006
PET OEF reactivity for hemodynamic compromise in occlusive vascular disease.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2007, Volume: 17, Issue:1

    Topics: Acetazolamide; Adult; Aged; Arterial Occlusive Diseases; Brain; Carotid Stenosis; Cerebral Arterial

2007
Acetazolamide challenge for three-dimensional time-of-flight MR angiography of the brain.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:4

    Topics: Acetazolamide; Adult; Aged; Angiography, Digital Subtraction; Arterial Occlusive Diseases; Arteries;

1994
Acetazolamide reactivity on 123I-IMP single photon emission computed tomography in patients with major cerebral artery occlusive disease: correlation with positron emission tomography parameters.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1994, Volume: 14, Issue:5

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amphetamines; Arterial Occlusive Diseases; Cerebral A

1994
Evaluation of cerebral vasoreactivity by three-dimensional time-of-flight magnetic resonance angiography.
    Stroke, 1994, Volume: 25, Issue:9

    Topics: Acetazolamide; Adult; Aged; Arterial Occlusive Diseases; Brain Ischemia; Cerebral Angiography; Cereb

1994
Acetazolamide-responsive migraine in CADASIL.
    Neurology, 1998, Volume: 50, Issue:5

    Topics: Acetazolamide; Cerebral Arterial Diseases; Dementia, Multi-Infarct; Genes, Dominant; Humans; Leukoen

1998
Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis.
    Journal of magnetic resonance imaging : JMRI, 1999, Volume: 10, Issue:5

    Topics: Acetazolamide; Adolescent; Aged; Aged, 80 and over; Carotid Stenosis; Cerebral Arterial Diseases; Ce

1999
Spontaneous improvement in reduced vasodilatory capacity in major cerebral arterial occlusive disease.
    Neuroradiology, 2000, Volume: 42, Issue:1

    Topics: Acetazolamide; Adult; Aged; Anticonvulsants; Arterial Occlusive Diseases; Brain Ischemia; Cerebral A

2000
Quantitative measurement of regional cerebral blood flow with flow-sensitive alternating inversion recovery imaging: comparison with [iodine 123]-iodoamphetamin single photon emission CT.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:3

    Topics: Acetazolamide; Aged; Brain; Cerebral Arterial Diseases; Cerebrovascular Circulation; Exercise Test;

2002